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  1. Article ; Online: CTNNB1 somatic mutations drive Wnt pathway activation in a case of incidental intranodal palisaded myofibroblastoma.

    Moreno de Juan, Germán / Montes Moreno, Santiago

    Revista espanola de patologia : publicacion oficial de la Sociedad Espanola de Anatomia Patologica y de la Sociedad Espanola de Citologia

    2023  Volume 56, Issue 4, Page(s) 279–283

    Abstract: Intranodal palisaded myofibroblastoma (IPM) is a rare stroma-derived spindle-cell neoplasm of the lymph node with myofibroblastic differentiation and CTNNB1 (β-catenin gene) somatic mutations. We present a case of IPM found incidentally in the staging of ...

    Abstract Intranodal palisaded myofibroblastoma (IPM) is a rare stroma-derived spindle-cell neoplasm of the lymph node with myofibroblastic differentiation and CTNNB1 (β-catenin gene) somatic mutations. We present a case of IPM found incidentally in the staging of lung adenocarcinoma. We describe the major histopathological and phenotypic features, including a palisaded bland spindle cell proliferation with myofibroblastic differentiation and Wnt pathway activation by immunohistochemistry, including β-catenin expression. Production of osteoid-like collagen directly from tumor cells was observed. We confirmed p.Gly34Arg CTNNB1 mutation by direct sequencing. We also reviewed the literature for similar cases.
    MeSH term(s) Humans ; beta Catenin/genetics ; beta Catenin/metabolism ; Wnt Signaling Pathway/genetics ; Lymph Nodes/pathology ; Neoplasms, Muscle Tissue/genetics ; Neoplasms, Muscle Tissue/metabolism ; Neoplasms, Muscle Tissue/pathology ; Mutation
    Chemical Substances beta Catenin ; CTNNB1 protein, human
    Language English
    Publishing date 2023-05-01
    Publishing country Spain
    Document type Case Reports
    ZDB-ID 2463888-2
    ISSN 1988-561X ; 1988-561X
    ISSN (online) 1988-561X
    ISSN 1988-561X
    DOI 10.1016/j.patol.2023.02.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Kikuchi-Fujimoto disease type lymph node reaction with increased plasmacytoid dendritic cells may appear as a side effect following COVID-19 vaccination: Report of a case and literature review.

    Moreno de Juan, Germán / Pérez Del Barrio, Amaia / Herrera Romero, Eduardo Germán / González Ruiz, Mario / Montes Moreno, Santiago

    Revista espanola de patologia : publicacion oficial de la Sociedad Espanola de Anatomia Patologica y de la Sociedad Espanola de Citologia

    2023  Volume 57, Issue 1, Page(s) 42–47

    Abstract: Subsequent to mass vaccination programs against COVID-19, diverse side effects have been described, both at the injection site, such as pain, redness and swelling, and systemic effects such as fatigue, headache, muscle or joint pain. On rare occasions, a ...

    Abstract Subsequent to mass vaccination programs against COVID-19, diverse side effects have been described, both at the injection site, such as pain, redness and swelling, and systemic effects such as fatigue, headache, muscle or joint pain. On rare occasions, a lymphadenopathic syndrome may develop, raising the clinical suspicion of a lymphoproliferative disorder. We present the case of a 30-year-old woman who developed self-limiting left axillary lymphadenopathy following COVID-19 vaccination. To date, only seven similar cases with a complete clinicopathological description have been published, and fourteen cases have been notified to the European adverse events databases (Eudravigilance) in relationship with vaccination against COVID-19. It is important to be aware of this potential complication when a lymphadenopathic syndrome develops following vaccination, to avoid unnecessary treatment.
    MeSH term(s) Adult ; Female ; Humans ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Dendritic Cells ; Histiocytic Necrotizing Lymphadenitis/etiology ; Lymph Nodes ; Vaccination
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2023-02-28
    Publishing country Spain
    Document type Review ; Case Reports
    ZDB-ID 2463888-2
    ISSN 1988-561X ; 1988-561X
    ISSN (online) 1988-561X
    ISSN 1988-561X
    DOI 10.1016/j.patol.2023.01.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Papillary fibroelastoma in the ligament of Marshall.

    Zubiaur, Jon / García Alcalde, Lucía / Moreno De Juan, German / Rodriguez Canedo, Cesar Augusto / Cuesta Cosgaya, Jose María

    European heart journal. Cardiovascular Imaging

    2023  Volume 25, Issue 2, Page(s) e91

    MeSH term(s) Humans ; Cardiac Papillary Fibroelastoma ; Echocardiography, Transesophageal ; Heart Neoplasms/diagnostic imaging ; Heart Neoplasms/surgery ; Ligaments ; Fibroma/diagnostic imaging ; Fibroma/surgery
    Language English
    Publishing date 2023-09-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2638345-7
    ISSN 2047-2412 ; 2047-2404
    ISSN (online) 2047-2412
    ISSN 2047-2404
    DOI 10.1093/ehjci/jead239
    Database MEDical Literature Analysis and Retrieval System OnLINE

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