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Article: Application of Ultrasound in Detecting and Removing Migrating Grass Awns in Dogs and Cats: A Systematic Review.

Caivano, Domenico / Corda, Francesca / Corda, Andrea / Moretti, Giulia / Bufalari, Antonello

Animals : an open access journal from MDPI

2023 Volume 13, Issue 13

Abstract: Migrating grass awns are an important cause of disease in dogs and cats. Plant awns can migrate into several body tissues and cavities because of their fusiform shape and backward-pointing barbs. Their migration causes inflammatory tissue reaction and ... ...

Abstract	Migrating grass awns are an important cause of disease in dogs and cats. Plant awns can migrate into several body tissues and cavities because of their fusiform shape and backward-pointing barbs. Their migration causes inflammatory tissue reaction and clinical signs depend upon their localization. Ultrasound has been described as a useful, noninvasive, and readily available tool to identify and guide vegetal foreign bodies removal in animals. The aim of this systematic review was to summarize current knowledge on the application of ultrasonography in the identification and removal of grass awns from various anatomic locations in dogs and cats. We selected and analyzed 46 papers on the application of ultrasonography in dogs and cats affected by migrating grass awns. The ultrasonographic appearance of grass awns is characteristic, although their size and location can influence the visualization and the attempt of removal. In some cases, migrating grass awns are not directly visualized by ultrasonography, but the lesions caused by their migration can be easily seen. Ultrasonography can be considered a useful diagnostic tool to localize and remove migrating grass awns; however, when the migration occurs in less accessible locations or discrete foreign bodies are present, this diagnostic tool should be considered as a part of a multidisciplinary approach with advanced diagnostic imaging modalities.
Language	English
Publishing date	2023-06-22
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2606558-7
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani13132071
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Application of Ultrasound in Detecting and Removing Migrating Grass Awns in Dogs and Cats: A Systematic Review

Caivano, Domenico / Corda, Francesca / Corda, Andrea / Moretti, Giulia / Bufalari, Antonello

Animals. 2023 June 22, v. 13, no. 13

2023

Abstract	Migrating grass awns are an important cause of disease in dogs and cats. Plant awns can migrate into several body tissues and cavities because of their fusiform shape and backward-pointing barbs. Their migration causes inflammatory tissue reaction and clinical signs depend upon their localization. Ultrasound has been described as a useful, noninvasive, and readily available tool to identify and guide vegetal foreign bodies removal in animals. The aim of this systematic review was to summarize current knowledge on the application of ultrasonography in the identification and removal of grass awns from various anatomic locations in dogs and cats. We selected and analyzed 46 papers on the application of ultrasonography in dogs and cats affected by migrating grass awns. The ultrasonographic appearance of grass awns is characteristic, although their size and location can influence the visualization and the attempt of removal. In some cases, migrating grass awns are not directly visualized by ultrasonography, but the lesions caused by their migration can be easily seen. Ultrasonography can be considered a useful diagnostic tool to localize and remove migrating grass awns; however, when the migration occurs in less accessible locations or discrete foreign bodies are present, this diagnostic tool should be considered as a part of a multidisciplinary approach with advanced diagnostic imaging modalities.
Keywords	diagnostic techniques ; grasses ; systematic review ; ultrasonics ; ultrasonography
Language	English
Dates of publication	2023-0622
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article ; Online
ZDB-ID	2606558-7
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani13132071
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Article ; Online: Recidivism risk in male adult sex offenders with psychopathic traits assessed by PCL-R: A systematic review.

Moretti, Giulia / Flutti, Emma / Colanino, Miriana / Ferlito, Danila / Amoresano, Livio / Travaini, Guido

Medicine, science, and the law

2023 Volume 64, Issue 1, Page(s) 41–51

Abstract: Psychopathy has been empirically associated with various forms of antisocial behavior including sexual assault. In fact, the lack of empathy characterizing psychopathic offenders may facilitate the perpetration of more extreme violence. This systematic ... ...

Abstract	Psychopathy has been empirically associated with various forms of antisocial behavior including sexual assault. In fact, the lack of empathy characterizing psychopathic offenders may facilitate the perpetration of more extreme violence. This systematic review aims to explore the relationship between psychopathy traits in male adult sex offenders and the increase in recidivism risk for any type of reoffence, with a special focus on sexual recidivism. From an initial sample of 757 articles related to the topic, only 14 were selected from the current literature at the end of the inclusion process. Each of these assessed the relation between psychopathy traits (measured by PCL-R) and recidivism risk in male sex offenders (age > 18), providing an effect size (quantitative findings). The results of their analysis agree with the currently available literature: the presence of psychopathic traits in sex offenders would seem to correlate with an increased risk of recidivism of general but non-sexual. Furthermore, almost half of the included works highlighted a positive relationship between psychopathy and violent reoffences. However, the limited availability of studies and the unevenness in their results indicate the need to expand future research in this direction.
MeSH term(s)	Adult ; Humans ; Male ; Middle Aged ; Criminals ; Recidivism ; Sex Offenses ; Violence ; Antisocial Personality Disorder
Language	English
Publishing date	2023-07-24
Publishing country	England
Document type	Systematic Review ; Journal Article ; Review
ZDB-ID	301137-9
ISSN	2042-1818 ; 0025-8024
ISSN (online)	2042-1818
ISSN	0025-8024
DOI	10.1177/00258024231187186
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Article ; Online: Mind the past: A systematic review on psychological autopsy.

Pacchioni, Federico / Bosia, Marta / Moretti, Giulia / Barbieri, Cristiano / Bellumore, Silvia / Travaini, Guido

Behavioral sciences & the law

2023 Volume 41, Issue 5, Page(s) 343–372

Abstract: Psychological Autopsy (PA) has become widespread to the point of being applied in many diverse fields. However, it is difficult to identify a standard model. In this systematic review, we focused on PA studies assessing mental illness as a major risk ... ...

Abstract	Psychological Autopsy (PA) has become widespread to the point of being applied in many diverse fields. However, it is difficult to identify a standard model. In this systematic review, we focused on PA studies assessing mental illness as a major risk factor for suicide. The research, performed on Scopus, Embase, and Pubmed to cover the last 20 years led to 321 reports of which 15 met the inclusion criteria. Results confirmed mental illness as the main risk factor for suicide, followed by specific socio-demographic factors and life events. The analysis of methodologies depicted a still highly heterogeneous scenario, especially regarding data collection and variables included. However, concerning psychiatric evaluations, an initial standardization process of PA models emerged. In conclusion, the approach is in evolution, and novel guidelines are needed to promote the application of PA as a fundamental tool to inform suicide prevention efforts and to assist forensic examiners in court.
MeSH term(s)	Humans ; Autopsy ; Suicide/psychology ; Mental Disorders/diagnosis ; Suicide Prevention ; Risk Factors
Language	English
Publishing date	2023-03-20
Publishing country	United States
Document type	Systematic Review ; Journal Article
ZDB-ID	232671-1
ISSN	1099-0798 ; 0735-3936
ISSN (online)	1099-0798
ISSN	0735-3936
DOI	10.1002/bsl.2619
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Article: Sedation quality of alfaxalone associated with butorphanol, methadone or pethidine in cats injected into the supraspinatus or the quadriceps muscle

Giannettoni, Giacomo / Moretti, Giulia / Menchetti, Laura / Pepe, Arianna / Bellocchi, Federica / Bufalari, Antonello / Nannarone, Sara

Journal of feline medicine and surgery. 2022 Aug., v. 24, no. 8

2022

Abstract: The aim of this study was to compare the quality of sedation with three different anaesthetic protocols (alfaxalone combined with butorphanol, methadone or pethidine) administered intramuscularly in cats, and to evaluate the influence of the injection ... ...

Abstract	The aim of this study was to compare the quality of sedation with three different anaesthetic protocols (alfaxalone combined with butorphanol, methadone or pethidine) administered intramuscularly in cats, and to evaluate the influence of the injection site (between supraspinatus and quadriceps muscles) on the onset and quality of sedation. A total of 151 cats were selected for this study. Cats were sedated with alfaxalone (3 mg/kg) combined with either butorphanol (0.3 mg/kg; n = 50), methadone (0.3 mg/kg; n = 53) or pethidine (5 mg/kg; n = 48). The combination was injected intramuscularly into the supraspinatus (n = 79) or quadriceps muscle (n = 72). The data included a scoring system for the quality of sedation and physiological parameters, such as heart rate (HR), respiratory rate, body temperature and occurrence of mydriasis, monitored during the first 30 mins of anaesthesia. The opioid associated with alfaxalone influenced the overall sedation score, the degree of myorelaxation, the occurrence of mydriasis and HR. The overall sedation score was poorer with butorphanol than with methadone (P = 0.008), and butorphanol induced a lower degree of myorelaxation than methadone (P = 0.013). The injection into the supraspinatus showed better qualitative results for sedation and a faster onset time (in about 3 mins) than that into the quadriceps (P <0.001). HR decreased from baseline (P <0.001) and over time (P <0.001), mainly in cats of the butorphanol–supraspinatus and pethidine–quadriceps groups (P = 0.004). The occurrence of mydriasis was lower after butorphanol than after methadone and pethidine (P = 0.025), while the incidence of side effects did not differ among groups. All three protocols provided a good quality of sedation and allowed performing the scheduled procedure. Moreover, the injection into the supraspinatus muscle showed superior results in all the qualitative scores of sedation and quicker onset time than that into the quadriceps muscle.
Keywords	alfaxalone ; anesthesia ; body temperature ; butorphanol ; cats ; heart rate ; injection site ; medicine ; methadone ; muscles ; pethidine ; respiratory rate ; sedation ; surgery
Language	English
Dates of publication	2022-08
Size	p. e269-e280.
Publishing place	SAGE Publications
Document type	Article
ZDB-ID	2049047-1
ISSN	1532-2750 ; 1098-612X
ISSN (online)	1532-2750
ISSN	1098-612X
DOI	10.1177/1098612X221104747
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Article: Methadone or Butorphanol as Pre-Anaesthetic Agents Combined with Romifidine in Horses Undergoing Elective Surgery: Qualitative Assessment of Sedation and Induction.

Nannarone, Sara / Giannettoni, Giacomo / Laurenza, Chiara / Giontella, Andrea / Moretti, Giulia

Animals : an open access journal from MDPI

2021 Volume 11, Issue 9

Abstract: While butorphanol is the most commonly used opioid in horses, methadone is not licensed in most countries. Our aim was to compare the effects of both drugs, combined with romifidine, regarding the quality of sedation and induction in horses undergoing ... ...

Abstract	While butorphanol is the most commonly used opioid in horses, methadone is not licensed in most countries. Our aim was to compare the effects of both drugs, combined with romifidine, regarding the quality of sedation and induction in horses undergoing elective surgery. Results indicate the suitability of both methadone and butorphanol in this patient population. Animals were scored 10 min after intravenous injection of sedatives. Despite lower overall sedation (OS) score in horses receiving methadone (
Language	English
Publishing date	2021-08-31
Publishing country	Switzerland
Document type	Journal Article
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani11092572
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Article ; Online: Sedation quality of alfaxalone associated with butorphanol, methadone or pethidine in cats injected into the supraspinatus or the quadriceps muscle.

Giannettoni, Giacomo / Moretti, Giulia / Menchetti, Laura / Pepe, Arianna / Bellocchi, Federica / Bufalari, Antonello / Nannarone, Sara

Journal of feline medicine and surgery

2022 Volume 24, Issue 8, Page(s) e269–e280

Abstract: Objectives: The aim of this study was to compare the quality of sedation with three different anaesthetic protocols (alfaxalone combined with butorphanol, methadone or pethidine) administered intramuscularly in cats, and to evaluate the influence of the ...

Abstract	Objectives: The aim of this study was to compare the quality of sedation with three different anaesthetic protocols (alfaxalone combined with butorphanol, methadone or pethidine) administered intramuscularly in cats, and to evaluate the influence of the injection site (between supraspinatus and quadriceps muscles) on the onset and quality of sedation. Methods: A total of 151 cats were selected for this study. Cats were sedated with alfaxalone (3 mg/kg) combined with either butorphanol (0.3 mg/kg; n = 50), methadone (0.3 mg/kg; n = 53) or pethidine (5 mg/kg; n = 48). The combination was injected intramuscularly into the supraspinatus (n = 79) or quadriceps muscle (n = 72). The data included a scoring system for the quality of sedation and physiological parameters, such as heart rate (HR), respiratory rate, body temperature and occurrence of mydriasis, monitored during the first 30 mins of anaesthesia. Results: The opioid associated with alfaxalone influenced the overall sedation score, the degree of myorelaxation, the occurrence of mydriasis and HR. The overall sedation score was poorer with butorphanol than with methadone ( Conclusions and relevance: All three protocols provided a good quality of sedation and allowed performing the scheduled procedure. Moreover, the injection into the supraspinatus muscle showed superior results in all the qualitative scores of sedation and quicker onset time than that into the quadriceps muscle.
MeSH term(s)	Anesthesia/veterinary ; Animals ; Butorphanol/pharmacology ; Butorphanol/therapeutic use ; Cat Diseases ; Cats ; Hypnotics and Sedatives ; Injections, Intramuscular/veterinary ; Meperidine ; Methadone/therapeutic use ; Mydriasis/veterinary ; Pregnanediones/pharmacology ; Quadriceps Muscle ; Rotator Cuff
Chemical Substances	Hypnotics and Sedatives ; Pregnanediones ; Meperidine (9E338QE28F) ; alphaxalone (BD07M97B2A) ; Butorphanol (QV897JC36D) ; Methadone (UC6VBE7V1Z)
Language	English
Publishing date	2022-06-28
Publishing country	England
Document type	Journal Article
ZDB-ID	2049047-1
ISSN	1532-2750 ; 1098-612X
ISSN (online)	1532-2750
ISSN	1098-612X
DOI	10.1177/1098612X221104747
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Article: Characterization of Primary Cultures of Normal and Neoplastic Canine Melanocytes

Sforna, Monica / Chiaradia, Elisabetta / Porcellato, Ilaria / Silvestri, Serenella / Moretti, Giulia / Mechelli, Luca / Brachelente, Chiara

Animals. 2021 Mar. 10, v. 11, no. 3

2021

Abstract: Although numerous animal models, especially mouse models, have been established for the study of melanoma, they often fail to accurately describe the mechanisms of human disease because of their anatomic, physiological, and immune differences. The dog, ... ...

Abstract	Although numerous animal models, especially mouse models, have been established for the study of melanoma, they often fail to accurately describe the mechanisms of human disease because of their anatomic, physiological, and immune differences. The dog, as a spontaneous model of melanoma, is nowadays considered one of the most valid alternatives due to the heterogeneity of clinical presentations and of histological and genetic similarities of canine melanoma with the human counterpart. The aim of the study was to optimize a protocol for the isolation and cultivation of healthy and neoplastic canine melanocytes derived from the same animal and obtained from cutaneous and mucosal (oral) sites. We obtained five primary tumor cell cultures (from 2 cutaneous melanoma, 2 mucosal melanoma and 1 lymph node metastasis) and primary normal melanocyte cell cultures (from normal skin and mucosa) from the same dogs. Immunocytochemical characterization with Melan A, PNL2 and S100 antibodies confirmed the melanocytic origin of the cells. This work contributes to expanding the case record of studies on canine melanoma cell cultures as suitable model to study human and canine melanoma. To the authors’ knowledge, this is the first report of isolation of normal skin and mucosal canine melanocytes.
Keywords	dogs ; histology ; human diseases ; humans ; lymph nodes ; melanocytes ; melanoma ; metastasis ; mucosa ; neoplasm cells
Language	English
Dates of publication	2021-0310
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
Note	NAL-light
ISSN	2076-2615
DOI	10.3390/ani11030768
Database	NAL-Catalogue (AGRICOLA)

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Article: Methadone or Butorphanol as Pre-Anaesthetic Agents Combined with Romifidine in Horses Undergoing Elective Surgery: Qualitative Assessment of Sedation and Induction

Nannarone, Sara / Giannettoni, Giacomo / Laurenza, Chiara / Giontella, Andrea / Moretti, Giulia

Animals. 2021 Aug. 31, v. 11, no. 9

2021

Abstract	While butorphanol is the most commonly used opioid in horses, methadone is not licensed in most countries. Our aim was to compare the effects of both drugs, combined with romifidine, regarding the quality of sedation and induction in horses undergoing elective surgery. Results indicate the suitability of both methadone and butorphanol in this patient population. Animals were scored 10 min after intravenous injection of sedatives. Despite lower overall sedation (OS) score in horses receiving methadone (p = 0.002), the quality and time of induction and intubation remained unchanged. None of the horses had the lowest OS score (no sedation), nor the highest score for ataxia (horse falling). Methadone induced a tendency for minor noise reaction yet minor head lowering scores, the latter being probably the most influencing parameter when scoring OS. Measured physiological parameters decreased in both groups, with greater bradycardia recorded after methadone (p = 0.017), including a higher incidence of atrioventricular blocks that resolved during general anaesthesia. The quality of induction was good–excellent in most of the animals. While comparisons between the degree of antinociception were beyond the scope of this study, analgesic potency might influence the choice when considering opioids as pre-anaesthetic drugs in combination with romifidine before surgery in equines.
Keywords	anesthesia ; butorphanol ; head ; horses ; intravenous injection ; methadone ; patients ; romifidine ; sedation ; surgery
Language	English
Dates of publication	2021-0831
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2606558-7
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani11092572
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Article: A Comparative Study of Intramuscular Alfaxalone- or Ketamine-Based Anesthetic Mixtures in Gray Squirrels Undergoing Gonadectomy: Clinical and Physiologic Findings.

Nannarone, Sara / Moretti, Giulia / Bellocchi, Federica / Menchetti, Laura / Bufalari, Antonello

Animals : an open access journal from MDPI

2020 Volume 10, Issue 8

Abstract: The gray squirrel is one of the most common invasive species in Europe, whose presence is dangerous for the survival of the European red squirrel. To cope with this biological invasion and to safeguard biodiversity, the LIFE+U-SAVEREDS project aims to ... ...

Abstract	The gray squirrel is one of the most common invasive species in Europe, whose presence is dangerous for the survival of the European red squirrel. To cope with this biological invasion and to safeguard biodiversity, the LIFE+U-SAVEREDS project aims to protect the red squirrel, by limiting the growth of the current population of gray squirrels and simultaneously promoting their eradication with surgical sterilization. This study compares two different anesthetic protocols, including dexmedetomidine (40 µg/kg) and midazolam (0.3 mg/kg) associated with ketamine (15 mg/kg;
Keywords	covid19
Language	English
Publishing date	2020-08-12
Publishing country	Switzerland
Document type	Journal Article
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani10081402
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