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  1. Book ; Conference proceedings: XIth European Meeting on Complement in Human Disease

    Morgan, B. P.

    [Cardiff, 8th - 11th September 2007]

    (Molecular immunology ; 44,16 = Special issue)

    2007  

    Event/congress European Meeting on Complement in Human Disease (11, 2007, Cardiff)
    Author's details guest ed.: B. Paul Morgan
    Series title Molecular immunology ; 44,16 = Special issue
    Collection
    Keywords Receptors, Complement ; Complement Activation ; Complement
    Language English
    Size XVII S., S. 3809 - 3994 : Ill., graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book ; Conference proceedings
    Note Enth. auch: Abstracts
    HBZ-ID HT015280643
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Psychometric properties of the Burnout Assessment Tool across four countries.

    Redelinghuys, Kleinjan / Morgan, Brandon

    BMC public health

    2023  Volume 23, Issue 1, Page(s) 824

    Abstract: Background: The Burnout Assessment Tool (BAT) is a new burnout measure developed to replace the Maslach Burnout Inventory (MBI). Studies have supported the psychometric properties and cross-cultural measurement invariance of the BAT. However, some ... ...

    Abstract Background: The Burnout Assessment Tool (BAT) is a new burnout measure developed to replace the Maslach Burnout Inventory (MBI). Studies have supported the psychometric properties and cross-cultural measurement invariance of the BAT. However, some unresolved questions remain. These questions are the appropriate level of score interpretation, convergent validity with the MBI, and measurement invariance using sample groups from countries outside of Europe.
    Methods: We used a cross-sectional survey approach to obtain 794 participants from Australia (n = 200), the Netherlands (n = 199), South Africa (n = 197), and the United States (n = 198). In brief, we used bifactor modelling to investigate the appropriate score interpretation and convergent validity with the MBI. Hereafter, we used the Rasch model and ordinal logistic regression to investigate differential item functioning.
    Results: The bifactor model showed a large general factor and four small group factors, which suggests calculating and interpreting a general burnout score. This model further shows that the BAT and MBI measure the same burnout construct but that the BAT is a more comprehensive burnout measure. Most items fit the Rasch model, and few showed non-negligible differential item functioning.
    Conclusions: Our results support the psychometric properties and cross-cultural measurement invariance of the BAT in Australia, the Netherlands, South Africa, and the United States. Furthermore, we provide some clarity on the three previously mentioned unresolved questions.
    MeSH term(s) Humans ; Psychometrics/methods ; Cross-Sectional Studies ; Reproducibility of Results ; Burnout, Psychological ; Burnout, Professional/diagnosis ; Surveys and Questionnaires
    Language English
    Publishing date 2023-05-04
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2041338-5
    ISSN 1471-2458 ; 1471-2458
    ISSN (online) 1471-2458
    ISSN 1471-2458
    DOI 10.1186/s12889-023-15604-z
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  3. Article ; Online: Perceptions of Professionalism and Preferences on Social Media in 2022.

    Murphrey, Morgan B / Fabi, Sabrina

    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.

    2023  Volume 49, Issue 5, Page(s) 535–537

    MeSH term(s) Humans ; Professionalism ; Social Media
    Language English
    Publishing date 2023-03-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1227586-4
    ISSN 1524-4725 ; 1076-0512
    ISSN (online) 1524-4725
    ISSN 1076-0512
    DOI 10.1097/DSS.0000000000003749
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  4. Article ; Online: Assessing diagnostic certainty for scurvy and rickets in human skeletal remains.

    Brickley, Megan B / Morgan, Brianne

    American journal of biological anthropology

    2023  Volume 181, Issue 4, Page(s) 637–645

    Abstract: Objectives: Identifying scurvy and rickets has important implications for understanding adaptations and variability among past communities, and bioarchaeologists now regularly evaluate these conditions. Due to the increased number of studies, cases with ...

    Abstract Objectives: Identifying scurvy and rickets has important implications for understanding adaptations and variability among past communities, and bioarchaeologists now regularly evaluate these conditions. Due to the increased number of studies, cases with less clear-cut lesions and variable preservation are now frequently reported. Despite an improved understanding of the biological mechanisms for disease expression, there is a lack of consensus on the language used to express diagnostic certainty, limiting comparability. This article aims to address these issues and provide recommendations on more consistent diagnostic terminology using widely accepted diagnostic methodology based on biological mechanisms.
    Materials and methods: We review diagnostic terms used in bioarchaeology by considering published cases of rickets, scurvy and co-occurrence alongside M.B.B.'s past project notes. We also consider differences in the diagnosis of rickets and scurvy in living and archeological individuals.
    Results: We provide recommendations on a framework that can be used to show diagnostic certainty in cases of rickets, scurvy, and co-occurrence. Core lesions of rickets and scurvy are used alongside a limited lexicon of diagnostic terminology based on the Istanbul protocol.
    Discussion: It is not the number of lesions that determines whether an individual is assigned to a particular diagnosis category, but rather the range and expression of lesions present. Avoiding a "tick-list" approach to core lesions of these diseases will be critical to ensure that identifying rickets and scurvy continues to contribute to understanding adaptations and variability among past communities. The framework allows more consistency in diagnostic certainty, facilitating greater comparability in research.
    MeSH term(s) Humans ; Scurvy/diagnosis ; Body Remains ; Rickets/diagnosis ; Archaeology ; Acclimatization
    Language English
    Publishing date 2023-06-19
    Publishing country United States
    Document type Review ; Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2692-7691
    ISSN (online) 2692-7691
    DOI 10.1002/ajpa.24799
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  5. Article ; Online: Sex and Season Affect Cortical Volumes in Free-Living Western Fence Lizards, Sceloporus occidentalis.

    Jude, Morgan B / Strand, Christine R

    Brain, behavior and evolution

    2023  Volume 98, Issue 3, Page(s) 160–170

    Abstract: The hippocampus plays an important role in spatial navigation and spatial learning across a variety of vertebrate species. Sex and seasonal differences in space use and behavior are known to affect hippocampal volume. Similarly, territoriality and ... ...

    Abstract The hippocampus plays an important role in spatial navigation and spatial learning across a variety of vertebrate species. Sex and seasonal differences in space use and behavior are known to affect hippocampal volume. Similarly, territoriality and differences in home range size are known to affect the volume of the reptile hippocampal homologues, the medial and dorsal cortices (MC, DC). However, studies have almost exclusively investigated males and little is known about sex or seasonal differences in MC and/or DC volumes in lizards. Here, we are the first to simultaneously examine sex and seasonal differences in MC and DC volumes in a wild lizard population. In Sceloporus occidentalis, males display territorial behaviors that are more pronounced during the breeding season. Given this sex difference in behavioral ecology, we expected males to have larger MC and/or DC volumes than females and for this difference to be most pronounced during the breeding season when territorial behavior is increased. Male and female S. occidentalis were captured from the wild during the breeding season and the post-breeding season and were sacrificed within 2 days of capture. Brains were collected and processed for histology. Cresyl-violet-stained sections were used to quantify brain region volumes. In these lizards, breeding females had larger DC volumes than breeding males and nonbreeding females. There was no sex or seasonal difference in MC volumes. Differences in spatial navigation in these lizards may involve aspects of spatial memory related to breeding other than territoriality that affect plasticity of the DC. This study highlights the importance of investigating sex differences and including females in studies of spatial ecology and neuroplasticity.
    MeSH term(s) Brain/physiology ; Hippocampus ; Male ; Female ; Animals ; Lizards/physiology ; Seasons ; Territoriality ; Sex Characteristics
    Language English
    Publishing date 2023-02-16
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1199-x
    ISSN 1421-9743 ; 0006-8977
    ISSN (online) 1421-9743
    ISSN 0006-8977
    DOI 10.1159/000529692
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  6. Article ; Online: The Utility of BIS™ Monitoring in Anesthesia for Elderly Patients.

    Temmermand, Rhea / Centimole, Zohn / Morgan, Brett / Greenier, Ewa

    AANA journal

    2024  Volume 92, Issue 3, Page(s) 7–13

    Abstract: Aging leads to anatomic and physiologic changes in the brain, making it more sensitive to the depressant effects of anesthetic medications and increasing the risk of postoperative neurocognitive complications such as postoperative delirium and ... ...

    Abstract Aging leads to anatomic and physiologic changes in the brain, making it more sensitive to the depressant effects of anesthetic medications and increasing the risk of postoperative neurocognitive complications such as postoperative delirium and postoperative cognitive dysfunction. This article explores the implications of anesthesia on elderly patients' brain health, emphasizing the heightened risk of postoperative neurocognitive disorders, and describes the BIS™ Monitoring System as a neuromonitoring tool for anesthesia professionals to assess the depth of anesthesia. The integration of the BIS Monitoring System into clinical practice can contribute to a more tailored and patient-centered approach to anesthesia management, ultimately improving perioperative outcomes and safety.
    MeSH term(s) Humans ; Aged ; Nurse Anesthetists ; Aged, 80 and over ; Anesthesia ; Monitoring, Intraoperative ; Consciousness Monitors
    Language English
    Publishing date 2024-05-17
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 603605-3
    ISSN 2162-5239 ; 0094-6354
    ISSN (online) 2162-5239
    ISSN 0094-6354
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  7. Article ; Online: LDI-MS scanner: Laser desorption ionization mass spectrometry-based biosensor standardization.

    Silina, Y E / Morgan, B

    Talanta

    2020  Volume 223, Issue Pt 1, Page(s) 121688

    Abstract: Amperometric biosensors have been widely utilized for the cost-effective and rapid analysis of various bioanalytes, for example glucose. However, a lack of standardization and validation procedures remains a major limitation in biosensor development. ... ...

    Abstract Amperometric biosensors have been widely utilized for the cost-effective and rapid analysis of various bioanalytes, for example glucose. However, a lack of standardization and validation procedures remains a major limitation in biosensor development. Therefore, despite rapid advances in material science driving the development of amperometric biosensors, to date only a few biosensors, detecting a limited range of analytes, are available on the market. It is believed, once this issue is addressed, it can significantly facilitate the next step in the overall concept "go to the market" production and implementation of amprerometric biosensors for a large industrial scale. Herein, we report on the use of laser desorption ionization mass spectrometry (LDI-MS) for the standardization of amperometric biosensors, based upon a complete and non-destructive characterization and validation of layer-by-layer (LbL) biosensors at each fabrication step. We reveal that specific ionization pathways of mediators, polymers and enzymes from the biosensor surface allows for robust quality control during LbL biosensor manufacture. Furthermore, this LDI-MS approach can also be used to monitor, and therefore ensure, the encapsulation of enzymes in one-step nanobiosensors. Specifically, we show that LDI-MS can be used for the rapid chemical profiling of LbL biosensors and one-step synthesized nanobiosensors, as well as to assess their synthesis quality and to monitor for batch-to-batch and intra- and inter-day changes in their function and behavior. Our novel approach will thus contribute to the future development, improved design and fine tuning of both conventional LbL-fabricated amperometric biosensors and one-step designed nanobiosensors.
    MeSH term(s) Biosensing Techniques ; Lasers ; Light ; Reference Standards ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
    Language English
    Publishing date 2020-09-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1500969-5
    ISSN 1873-3573 ; 0039-9140
    ISSN (online) 1873-3573
    ISSN 0039-9140
    DOI 10.1016/j.talanta.2020.121688
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  8. Article ; Online: Correction to: Complement in the pathogenesis of Alzheimer's disease.

    Paul Morgan, B

    Seminars in immunopathology

    2018  Volume 40, Issue 5, Page(s) 517

    Abstract: The presentation of Fig. 2 was incorrect. ...

    Abstract The presentation of Fig. 2 was incorrect.
    Language English
    Publishing date 2018-09-18
    Publishing country Germany
    Document type Journal Article ; Published Erratum
    ZDB-ID 2316828-6
    ISSN 1863-2300 ; 1863-2297
    ISSN (online) 1863-2300
    ISSN 1863-2297
    DOI 10.1007/s00281-018-0709-6
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  9. Book: Complement methods and protocols

    Morgan, B. P.

    (Methods in molecular biology ; 150)

    2000  

    Author's details ed. by B. Paul Morgan
    Series title Methods in molecular biology ; 150
    Collection
    Keywords Komplement ; Molekularbiologie ; Methode ; Biochemische Analyse
    Subject Bioanalytische Chemie ; Bioanalytik ; Analytische Biochemie ; Complement ; Komplementsystem ; Methodik ; Verfahren ; Technik ; Methoden ; Molekulare Biologie
    Language English
    Size IX, 268 S. : graph. Darst.
    Publisher Humana Press
    Publishing place Totowa, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT012741671
    ISBN 0-89603-654-5 ; 978-0-89603-654-3
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2000 A 2207 order for loan Magazin

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  10. Article ; Online: Opportunities for Poetic Analysis in Qualitative Nursing Research.

    Tarbi, Elise C / Morgan, Brianna

    Nursing research

    2022  Volume 71, Issue 4, Page(s) 322–327

    Abstract: Background: The voices of people living with serious, life-limiting illnesses are often underrepresented in research. Furthermore, a biomedical bias toward treatment and stigma associated with illness prevents healthcare providers from engaging with ... ...

    Abstract Background: The voices of people living with serious, life-limiting illnesses are often underrepresented in research. Furthermore, a biomedical bias toward treatment and stigma associated with illness prevents healthcare providers from engaging with topics critical for people living with serious illness, such as existential communication and inner strength. Poetry is an established method of analysis and dissemination in qualitative research but is underutilized by nursing researchers.
    Objectives: The purpose of this article is to demonstrate the inherent opportunities in using poetry in nursing research to highlight the voices and issues of people whose experiences are outside the assumed norms of the biomedical paradigm.
    Methods: We apply methods of poetic analysis to qualitative data sets that highlight the voice of people living with serious illness-in naturally occurring palliative care conversations and dyadic interviews of people with dementia and their care partners. Methods of poetic analysis include poetic transcription and voice poems.
    Results: Methods of poetic analysis allowed us to engage with the data reflexively to intensify and evoke the deeper meaning of narratives. Poetic analysis served to center the participant's voices by using their own words to demonstrate themes. Poems are a uniquely accessible method of disseminating complex findings, as poems relay layered cognitive and emotional meaning resonant of universal human experiences in a concise and relatable format.
    Discussion: Especially in circumstances where participant's voices are underrepresented, poetic analysis enables nurse researchers to challenge normative assumptions and reimagine a difference-centered society. Our findings offer opportunities to incorporate poetry into clinical and research nursing training to better meet the needs of the populations we serve.
    MeSH term(s) Communication ; Humans ; Narration ; Nursing Research ; Palliative Care ; Qualitative Research
    Language English
    Publishing date 2022-01-24
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 80332-7
    ISSN 1538-9847 ; 0029-6562
    ISSN (online) 1538-9847
    ISSN 0029-6562
    DOI 10.1097/NNR.0000000000000580
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