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  1. Article ; Online: Optical coherence tomography imaging of coronary thrombosis developed after rotational atherectomy despite appropriate antithrombotic therapy.

    Komaki, Soichi / Moribayashi, Kohei / Matsuura, Yunosuke / Tanaka, Hiroki / Kaikita, Koichi

    Cardiovascular intervention and therapeutics

    2024  

    Language English
    Publishing date 2024-05-01
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2581654-8
    ISSN 1868-4297 ; 1868-4300
    ISSN (online) 1868-4297
    ISSN 1868-4300
    DOI 10.1007/s12928-024-01009-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4771: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Optimal Antithrombotic Therapy in Patients Undergoing Percutaneous Coronary Intervention: A Focused Review on High Bleeding Risk.

    Matsuura, Yunosuke / Moribayashi, Kohei / Kaikita, Koichi

    Journal of atherosclerosis and thrombosis

    2022  Volume 29, Issue 10, Page(s) 1409–1420

    Abstract: Dual antiplatelet therapy (DAPT) is a therapeutic cornerstone to prevent stent thrombosis following percutaneous coronary intervention (PCI) for coronary artery disease (CAD). However, the longer the DAPT duration, the higher the incidence of bleeding ... ...

    Abstract Dual antiplatelet therapy (DAPT) is a therapeutic cornerstone to prevent stent thrombosis following percutaneous coronary intervention (PCI) for coronary artery disease (CAD). However, the longer the DAPT duration, the higher the incidence of bleeding and mortality. Since the advent of second-generation drug-eluting stents (DES), the continuous evolution of DES has reduced the thrombotic risk and allowed for a shorter DAPT duration. On the other hand, concerns on the elevated risk of bleeding during antithrombotic therapy have been further raised due to the growing number of elderly CAD patients with multiple comorbidities. The consequent debate topic over post-PCI antithrombotic therapy has shifted from simply reducing thrombotic risk to safely minimizing bleeding risk. Due to the significant impact of bleeding on clinical outcomes, including prognosis, current guidelines on antithrombotic therapy for CAD prioritize stratification of patients at a high bleeding risk (HBR) as the top consideration in determining post-PCI antithrombotic therapy. Achieving optimal antithrombotic therapy for each patient undergoing PCI requires a better understanding of the clinical variables constituting the balance of bleeding and thrombotic risk. This review highlights relevant evidence required to optimize antithrombotic therapy for HBR patients undergoing PCI.
    MeSH term(s) Aged ; Coronary Artery Disease/drug therapy ; Coronary Artery Disease/surgery ; Drug Therapy, Combination ; Fibrinolytic Agents/adverse effects ; Hemorrhage/chemically induced ; Hemorrhage/prevention & control ; Humans ; Percutaneous Coronary Intervention/adverse effects ; Platelet Aggregation Inhibitors/adverse effects ; Thrombosis/epidemiology ; Thrombosis/etiology ; Thrombosis/prevention & control ; Treatment Outcome
    Chemical Substances Fibrinolytic Agents ; Platelet Aggregation Inhibitors
    Language English
    Publishing date 2022-08-06
    Publishing country Japan
    Document type Journal Article ; Review
    ZDB-ID 2011474-6
    ISSN 1880-3873 ; 1340-3478
    ISSN (online) 1880-3873
    ISSN 1340-3478
    DOI 10.5551/jat.RV17066
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5192: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Stratifying Bleeding Risk and Beyond　- Predicting Where Bleeding Will Occur.

    Moribayashi, Kohei / Matsuura, Yunosuke / Kaikita, Koichi

    Circulation journal : official journal of the Japanese Circulation Society

    2022  Volume 86, Issue 5, Page(s) 784–786

    MeSH term(s) Hemorrhage/etiology ; Humans ; Platelet Aggregation Inhibitors ; Risk Assessment ; Risk Factors
    Chemical Substances Platelet Aggregation Inhibitors
    Language English
    Publishing date 2022-03-12
    Publishing country Japan
    Document type Editorial ; Comment
    ZDB-ID 2068090-9
    ISSN 1347-4820 ; 1346-9843
    ISSN (online) 1347-4820
    ISSN 1346-9843
    DOI 10.1253/circj.CJ-22-0091
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui IV Zs.74: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Very Late Stent Thrombosis Complicating Immune Thrombocytopenia: Insights From Optical Coherence Tomography and Thrombopathology.

    Shimazu, Hisanobu / Matsuura, Yunosuke / Moribayashi, Kohei / Gi, Toshihiro / Suiko, Yosuke / Tanaka, Hiroki / Komaki, Soichi / Ishikawa, Tetsunori / Yamashita, Atsushi / Kaikita, Koichi

    JACC. Case reports

    2023  Volume 24, Page(s) 102017

    Abstract: Immune thrombocytopenia (ITP) carries bleeding and thrombotic risks; however, thromboses associated with ITP have not been histologically examined. This report presents optical coherence tomography images of the culprit lesion and histology of coronary ... ...

    Abstract Immune thrombocytopenia (ITP) carries bleeding and thrombotic risks; however, thromboses associated with ITP have not been histologically examined. This report presents optical coherence tomography images of the culprit lesion and histology of coronary aspirates in very late stent thrombosis complicating severe ITP, providing evidence of platelet-rich thrombus formation. (
    Language English
    Publishing date 2023-09-12
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2666-0849
    ISSN (online) 2666-0849
    DOI 10.1016/j.jaccas.2023.102017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Nitroglycerin use and adverse clinical outcomes in elderly patients with acute coronary syndrome.

    Komaki, Soichi / Matsuura, Yunosuke / Tanaka, Hiroki / Moribayashi, Kohei / Yamamura, Yoshimasa / Kurogi, Kazumasa / Ideguchi, Takeshi / Yamamoto, Nobuyasu / Nakai, Michikazu / Tsuruda, Toshihiro / Kaikita, Koichi

    Open heart

    2024  Volume 11, Issue 1

    Abstract: Objective: The primary care for acute coronary syndrome (ACS) includes the administration of nitroglycerin (GTN). This study aimed to investigate the association between the use of GTN before percutaneous coronary intervention (PCI) for ACS and clinical ...

    Abstract Objective: The primary care for acute coronary syndrome (ACS) includes the administration of nitroglycerin (GTN). This study aimed to investigate the association between the use of GTN before percutaneous coronary intervention (PCI) for ACS and clinical outcomes.
    Methods: Nine-hundred and forty-seven patients who underwent PCI for ACS were examined and classified into two groups: those who were treated with GTN before PCI (GTN group) and those who were not (non-GTN group). The incidence of major adverse cardiovascular events (MACE), which consist of all-cause mortality, non-fatal myocardial infarction, stroke and rehospitalisation for heart failure at 1 year, was compared between the two groups.
    Results: This study identified 289 patients with ACS who used GTN preceding PCI. Pre-PCI systolic blood pressure was significantly lower in the GTN group than in the non-GTN group (median (IQR); 132.0 (110.0-143.5) mm Hg vs 134.0 (112.0-157.0) mm Hg, respectively, p=0.03). Multivariate Cox regression analysis indicated that GTN use preceding PCI showed an independent association with the incidence of MACE (HR 1.57; 95% CI 1.09-2.28; p=0.016). Overall, the incidence of MACE 1 year after PCI for ACS was significantly higher in the GTN group than in the non-GTN group (log-rank test, p=0.024); however, this trend was consistently found in elderly patients aged ≥75 years (p=0.002) but not in non-elderly patients aged <75 years (p=0.773).
    Conclusions: GTN use preceding PCI for ACS is associated with lower blood pressure and adverse clinical outcomes in elderly patients.
    MeSH term(s) Aged ; Humans ; Middle Aged ; Acute Coronary Syndrome/diagnosis ; Acute Coronary Syndrome/therapy ; Nitroglycerin/adverse effects ; Percutaneous Coronary Intervention/adverse effects ; Treatment Outcome ; Myocardial Infarction/epidemiology
    Chemical Substances Nitroglycerin (G59M7S0WS3)
    Language English
    Publishing date 2024-01-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2747269-3
    ISSN 2053-3624
    ISSN 2053-3624
    DOI 10.1136/openhrt-2023-002494
    Database MEDical Literature Analysis and Retrieval System OnLINE

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