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Article ; Online: Corrigendum to "Adelmidrol, a palmitoylethanolamide analogue, as a new pharmacological treatment for the management of acute and chronic inflammation" [Biochem. Pharmacol. 119 (2016) 27-41].

Impellizzeri, Daniela / Di Paola, Rosanna / Cordaro, Marika / Gugliandolo, Enrico / Casili, Giovanna / Morittu, Valeria Maria / Britti, Domenico / Esposito, Emanuela / Cuzzocrea, Salvatore

Biochemical pharmacology

2024 Volume 223, Page(s) 116105

Language	English
Publishing date	2024-03-20
Publishing country	England
Document type	Published Erratum
ZDB-ID	208787-x
ISSN	1873-2968 ; 0006-2952
ISSN (online)	1873-2968
ISSN	0006-2952
DOI	10.1016/j.bcp.2024.116105
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Recent Advances in the Determination of Milk Adulterants and Contaminants by Mid-Infrared Spectroscopy

Ceniti, Carlotta / Spina, Anna Antonella / Piras, Cristian / Oppedisano, Francesca / Tilocca, Bruno / Roncada, Paola / Britti, Domenico / Morittu, Valeria Maria

Foods. 2023 July 31, v. 12, no. 15

2023

Abstract: The presence of chemical contaminants, toxins, or veterinary drugs in milk, as well as the adulteration of milk from different species, has driven the development of new tools to ensure safety and quality. Several analytical procedures have been proposed ...

Abstract	The presence of chemical contaminants, toxins, or veterinary drugs in milk, as well as the adulteration of milk from different species, has driven the development of new tools to ensure safety and quality. Several analytical procedures have been proposed for the rapid screening of hazardous substances or the selective confirmation of the authenticity of milk. Mid-infrared spectroscopy and Fourier-transform infrared have been two of the most relevant technologies conventionally employed in the dairy industry. These fingerprint methodologies can be very powerful in determining the trait of raw material without knowing the identity of each constituent, and several aspects suggest their potential as a screening method to detect adulteration. This paper reviews the latest advances in applying mid-infrared spectroscopy for the detection and quantification of adulterants, milk dilution, the presence of pathogenic bacteria, veterinary drugs, and hazardous substances in milk.
Keywords	adulterated products ; chemical pollutants ; dairy industry ; milk ; raw materials ; spectroscopy
Language	English
Dates of publication	2023-0731
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article ; Online
ZDB-ID	2704223-6
ISSN	2304-8158
ISSN	2304-8158
DOI	10.3390/foods12152917
Database	NAL-Catalogue (AGRICOLA)

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Article: Mid-infrared (MIR) spectroscopy for the detection of cow's milk in buffalo milk.

Spina, Anna Antonella / Ceniti, Carlotta / Piras, Cristian / Tilocca, Bruno / Britti, Domenico / Morittu, Valeria Maria

Journal of animal science and technology

2022 Volume 64, Issue 3, Page(s) 531–538

Abstract: In Italy, buffalo mozzarella is a largely sold and consumed dairy product. The fraudulent adulteration of buffalo milk with cheaper and more available milk of other species is very frequent. In the present study, Fourier transform infrared spectroscopy ( ... ...

Abstract	In Italy, buffalo mozzarella is a largely sold and consumed dairy product. The fraudulent adulteration of buffalo milk with cheaper and more available milk of other species is very frequent. In the present study, Fourier transform infrared spectroscopy (FTIR), in combination with multivariate analysis by partial least square (PLS) regression, was applied to quantitatively detect the adulteration of buffalo milk with cow milk by using a fully automatic equipment dedicated to the routine analysis of the milk composition. To enhance the heterogeneity, cow and buffalo bulk milk was collected for a period of over three years from different dairy farms. A total of 119 samples were used for the analysis to generate 17 different concentrations of buffalo-cow milk mixtures. This procedure was used to enhance variability and to properly randomize the trials. The obtained calibration model showed an
Language	English
Publishing date	2022-05-31
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2775231-8
ISSN	2055-0391
ISSN	2055-0391
DOI	10.5187/jast.2022.e22
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: The Effect of Feeding a Total Mixed Ration with an

Spina, Anna Antonella / Lopreiato, Vincenzo / Britti, Domenico / Minuti, Andrea / Trevisi, Erminio / Tilocca, Bruno / Perri, Alessia / Morittu, Valeria Maria

Animals : an open access journal from MDPI

2023 Volume 14, Issue 1

Abstract: The aim of the current study was to evaluate the effect of the starter restriction and of ... ...

Abstract	The aim of the current study was to evaluate the effect of the starter restriction and of the
Language	English
Publishing date	2023-12-25
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2606558-7
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani14010081
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Recent Advances in the Determination of Milk Adulterants and Contaminants by Mid-Infrared Spectroscopy.

Ceniti, Carlotta / Spina, Anna Antonella / Piras, Cristian / Oppedisano, Francesca / Tilocca, Bruno / Roncada, Paola / Britti, Domenico / Morittu, Valeria Maria

Foods (Basel, Switzerland)

2023 Volume 12, Issue 15

Abstract	The presence of chemical contaminants, toxins, or veterinary drugs in milk, as well as the adulteration of milk from different species, has driven the development of new tools to ensure safety and quality. Several analytical procedures have been proposed for the rapid screening of hazardous substances or the selective confirmation of the authenticity of milk. Mid-infrared spectroscopy and Fourier-transform infrared have been two of the most relevant technologies conventionally employed in the dairy industry. These fingerprint methodologies can be very powerful in determining the trait of raw material without knowing the identity of each constituent, and several aspects suggest their potential as a screening method to detect adulteration. This paper reviews the latest advances in applying mid-infrared spectroscopy for the detection and quantification of adulterants, milk dilution, the presence of pathogenic bacteria, veterinary drugs, and hazardous substances in milk.
Language	English
Publishing date	2023-07-31
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2704223-6
ISSN	2304-8158
ISSN	2304-8158
DOI	10.3390/foods12152917
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Utilization of Dairy By-Products as a Source of Functional and Health Compounds-The Role of Ovine Colostrum and Milk Whey on Chronic Myeloid Leukemia Cells.

Ceniti, Carlotta / Ambrosio, Rosa Luisa / Bria, Jessica / Di Vito, Anna / Tilocca, Bruno / Anastasio, Aniello / Britti, Domenico / Morittu, Valeria Maria / Chiarella, Emanuela

Foods (Basel, Switzerland)

2023 Volume 12, Issue 9

Abstract: Nowadays, the search for food products that promote consumers' health has gained interest, and dairy by-products, due to their biological quality, could have a prominent position among products with health benefits. However, little is known about their ... ...

Abstract	Nowadays, the search for food products that promote consumers' health has gained interest, and dairy by-products, due to their biological quality, could have a prominent position among products with health benefits. However, little is known about their activity on cancer cells. This study aimed to provide evidence about the effect of ovine colostrum and milk whey on K562 cells, a model of the human chronic myeloid leukemia cell line. The exposure of K562 cells to a single administration of sheep by-products at different concentrations for three days and three treatments for three days was carried out. Using a flow cytometric approach, we found that CD235a expression remained stable in the cells exposed to ovine whey (milk and colostrum) at concentrations ranging from 1 ng/mL to 100 μg/mL, after three days from one or three administrations, respectively. A significant reduction in fluorescent cells was observed in the populations exposed to 1 mg/mL of both milk and colostrum at the same time points. In these conditions, the size and granularity of the leukemic cells also changed, with a substantial reduction in the number of actively dividing cells in the S phase of the cell cycle. This phenomenon was highlighted by the Annexin V/PI cytofluorimetric test, which is able to provide quantitative results regarding the population of cells in early or late apoptosis or necrotic cells after exposure to a single dose or three doses of colostrum or sheep whey for three days, respectively. This report showed that both colostrum and milk whey were able to modify the phenotypic profile and cell cycle of the K562 cell line, inducing apoptosis at the highest concentration.
Language	English
Publishing date	2023-04-23
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2704223-6
ISSN	2304-8158
ISSN	2304-8158
DOI	10.3390/foods12091752
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The Bee Gut Microbiota: Bridging Infective Agents Potential in the One Health Context.

Tilocca, Bruno / Greco, Viviana / Piras, Cristian / Ceniti, Carlotta / Paonessa, Mariachiara / Musella, Vincenzo / Bava, Roberto / Palma, Ernesto / Morittu, Valeria Maria / Spina, Anna Antonella / Castagna, Fabio / Urbani, Andrea / Britti, Domenico / Roncada, Paola

International journal of molecular sciences

2024 Volume 25, Issue 7

Abstract: The bee gut microbiota plays an important role in the services the bees pay to the environment, humans and animals. Alongside, gut-associated microorganisms are vehiculated between apparently remote habitats, promoting microbial heterogeneity of the ... ...

Abstract	The bee gut microbiota plays an important role in the services the bees pay to the environment, humans and animals. Alongside, gut-associated microorganisms are vehiculated between apparently remote habitats, promoting microbial heterogeneity of the visited microcosms and the transfer of the microbial genetic elements. To date, no metaproteomics studies dealing with the functional bee microbiota are available. Here, we employ a metaproteomics approach to explore a fraction of the bacterial, fungal, and unicellular parasites inhabiting the bee gut. The bacterial community portrays a dynamic composition, accounting for specimens of human and animal concern. Their functional features highlight the vehiculation of virulence and antimicrobial resistance traits. The fungal and unicellular parasite fractions include environment- and animal-related specimens, whose metabolic activities support the spatial spreading of functional features. Host proteome depicts the major bee physiological activities, supporting the metaproteomics strategy for the simultaneous study of multiple microbial specimens and their host-crosstalks. Altogether, the present study provides a better definition of the structure and function of the bee gut microbiota, highlighting its impact in a variety of strategies aimed at improving/overcoming several current hot topic issues such as antimicrobial resistance, environmental pollution and the promotion of environmental health.
MeSH term(s)	Humans ; Bees ; Animals ; Gastrointestinal Microbiome ; One Health ; Microbiota ; Cross Reactions ; Anti-Infective Agents
Chemical Substances	Anti-Infective Agents
Language	English
Publishing date	2024-03-27
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms25073739
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Utilization of Dairy By-Products as a Source of Functional and Health Compounds—The Role of Ovine Colostrum and Milk Whey on Chronic Myeloid Leukemia Cells

Ceniti, Carlotta / Ambrosio, Rosa Luisa / Bria, Jessica / Di Vito, Anna / Tilocca, Bruno / Anastasio, Aniello / Britti, Domenico / Morittu, Valeria Maria / Chiarella, Emanuela

Foods. 2023 Apr. 23, v. 12, no. 9

2023

Abstract: Nowadays, the search for food products that promote consumers’ health has gained interest, and dairy by-products, due to their biological quality, could have a prominent position among products with health benefits. However, little is known about their ... ...

Abstract	Nowadays, the search for food products that promote consumers’ health has gained interest, and dairy by-products, due to their biological quality, could have a prominent position among products with health benefits. However, little is known about their activity on cancer cells. This study aimed to provide evidence about the effect of ovine colostrum and milk whey on K562 cells, a model of the human chronic myeloid leukemia cell line. The exposure of K562 cells to a single administration of sheep by-products at different concentrations for three days and three treatments for three days was carried out. Using a flow cytometric approach, we found that CD235a expression remained stable in the cells exposed to ovine whey (milk and colostrum) at concentrations ranging from 1 ng/mL to 100 μg/mL, after three days from one or three administrations, respectively. A significant reduction in fluorescent cells was observed in the populations exposed to 1 mg/mL of both milk and colostrum at the same time points. In these conditions, the size and granularity of the leukemic cells also changed, with a substantial reduction in the number of actively dividing cells in the S phase of the cell cycle. This phenomenon was highlighted by the Annexin V/PI cytofluorimetric test, which is able to provide quantitative results regarding the population of cells in early or late apoptosis or necrotic cells after exposure to a single dose or three doses of colostrum or sheep whey for three days, respectively. This report showed that both colostrum and milk whey were able to modify the phenotypic profile and cell cycle of the K562 cell line, inducing apoptosis at the highest concentration.
Keywords	apoptosis ; cell lines ; colostrum ; flow cytometry ; fluorescence ; humans ; interphase ; milk ; models ; myeloid leukemia ; neoplasm cells ; phenotype ; sheep ; whey
Language	English
Dates of publication	2023-0423
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article ; Online
ZDB-ID	2704223-6
ISSN	2304-8158
ISSN	2304-8158
DOI	10.3390/foods12091752
Database	NAL-Catalogue (AGRICOLA)

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Article: Effect of Integration of Linseed and Vitamin E in Charolaise × Podolica Bulls’ Diet on Fatty Acids Profile, Beef Color and Lipid Stability

Morittu, Valeria Maria / Spina, Anna Antonella / Iommelli, Piera / Poerio, Anselmo / Oliverio, Francesco Vincenzo / Britti, Domenico / Tudisco, Raffaella

Agriculture (Basel). 2021 Oct. 21, v. 11, no. 11

2021

Abstract: Dietary supplementation with oilseeds improves the fatty acid profiles of meat, but results are often inconsistent. This study aimed to assess the effects of dietary linseed and vitamin E supplementation on fatty acid profile, cholesterol content and ... ...

Abstract	Dietary supplementation with oilseeds improves the fatty acid profiles of meat, but results are often inconsistent. This study aimed to assess the effects of dietary linseed and vitamin E supplementation on fatty acid profile, cholesterol content and color stability of beef samples. Dorsal subcutaneous fat samples were subjected to lipid stability assessment. Eighteen young bulls (385 ± 15 kg BW, age 8–9 months) were allocated into three homogeneous groups, each receiving ad libitum wheat straw and concentrate only (CON = 5.5 kg/day), concentrate with linseed (LIN = 80 g/kg, i.e., 440 g/head/day), and concentrate with linseed plus vitamin E (L + E = 80 g/kg, i.e., 440 g/head/day + 2500 IU/head/day of Vitamin E). Group L+E showed significantly lower cholesterol content, lower n-6/n-3 ratio and a higher PUFA percentage compared to the CON group. Meat color was affected by feeding LIN with a decrease in a, b, and C* compared to the CON group. The experimental diets increased H° values compared to the CON group. A positive effect of vitamin E in protecting lipids of dorsal subcutaneous depots from oxidation was detected in group L+E compared to group LIN. The supplementation with extruded linseeds in the diet had positive effects on the nutritional profile of the meat. When vitamin E was included, linseed did not alter the color of meat, and the lipid stability of the subcutaneous fat improved.
Keywords	agriculture ; beef ; cholesterol ; color ; dietary supplements ; fatty acid composition ; linseed ; nutrient content ; oxidation ; subcutaneous fat ; vitamin E ; wheat straw
Language	English
Dates of publication	2021-1021
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2651678-0
ISSN	2077-0472
ISSN	2077-0472
DOI	10.3390/agriculture11111032
Database	NAL-Catalogue (AGRICOLA)

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Article: Evaluation of freezing point in milk from buffalos reared in Calabria, Italy

Ceniti, Carlotta / Britti, Domenico / Trimboli, Francesca / Morittu, Valeria Maria / Lopreiato, Vincenzo / Costanzo, Nicola

Italian journal of food safety. 2019 May 23, v. 8, no. 2

2019

Abstract: Evaluation of freezing point is one of the most common technique used to detect milk adulteration such as addition of external water to increase volume. The aim of this study was to evaluate the freezing point of buffalo milk using infrared spectroscopy ... ...

Abstract	Evaluation of freezing point is one of the most common technique used to detect milk adulteration such as addition of external water to increase volume. The aim of this study was to evaluate the freezing point of buffalo milk using infrared spectroscopy and to assess how it is influenced by other milk components. A total of 361 individual buffalo milk samples were collected monthly from March to August of 2017 in a dairy farm in Catanzaro district, Italy. Samples were tested for freezing point, urea, acetone and beta-hydroxybutyrate, percent of fat, protein, lactose, casein, by Fourier Transformed Spectroscopy. The pH and daily milk production were also recorded. Freezing point ranged from -0.574°C to - 0.512°C and the mean values was -0.545°C ±0.010. According to lactation stage, freezing point decreased until 210 days post-partum reaching the minimum value of −0.550°C, then it slightly increased during lactation; according to sampling month the highest and lowest values were recorded in August and June, respectively. A positive correlation between freezing point and lactose content were evidenced (r=0.1806, P<0.05). Moreover, a faintly positive correlation was also found between freezing point and beta-idroxibutirrate (r=0.0869, P<0.05) and acetone (r=0.0096, P<0.05), whereas a negative correlation with fat (r=−0.2356, P<0.05), protein (r=-0.1855, P<0.05), casein (r=-0.2127, P<0.05) and urea (r=-0.1229, P<0.05) was evidenced.
Keywords	3-hydroxybutyric acid ; acetone ; adulterated products ; buffalo milk ; buffaloes ; casein ; dairy farming ; freezing point ; infrared spectroscopy ; lactation stage ; lactose ; milk ; milk production ; pH ; rearing ; urea ; Italy
Language	English
Dates of publication	2019-0523
Publishing place	PAGEPress Publications
Document type	Article
ZDB-ID	2717104-8
ISSN	2239-7132
ISSN	2239-7132
DOI	10.4081/ijfs.2019.7895
Database	NAL-Catalogue (AGRICOLA)

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