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  1. Article ; Online: Onset of nephrotic syndrome concomitant to SARS-CoV-2 infection in a 3-year-old child.

    Morreale, Alessia / Casciana, Maria Luisa

    Pediatric nephrology (Berlin, Germany)

    2021  Volume 37, Issue 1, Page(s) 225

    MeSH term(s) COVID-19 ; Child, Preschool ; Humans ; Nephrotic Syndrome/diagnosis ; SARS-CoV-2
    Language English
    Publishing date 2021-10-14
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 631932-4
    ISSN 1432-198X ; 0931-041X
    ISSN (online) 1432-198X
    ISSN 0931-041X
    DOI 10.1007/s00467-021-05307-1
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    Zs.A 2196: Show issues Location:
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  2. Article: L’intoxication chronique au paracétamol : cause iatrogène sous-diagnostiquée d’acidose métabolique à trou anionique augmenté.

    Morreale, A / Canivet, J L / Charlier, C / Misset, B

    Revue medicale de Liege

    2021  Volume 76, Issue 7-8, Page(s) 620–624

    Abstract: The occurrence of metabolic acidosis with increased anion gap in the context of chronic paracetamol intoxication is an easily treatable clinical situation. Its rapid recognition is essential given its complete reversibility in the event of adequate ... ...

    Title translation Chronic paracetamol intoxication : under-diagnosed iatrogenic cause of metabolic acidosis with increased anion gap.
    Abstract The occurrence of metabolic acidosis with increased anion gap in the context of chronic paracetamol intoxication is an easily treatable clinical situation. Its rapid recognition is essential given its complete reversibility in the event of adequate management by eviction of the toxic agent, in this case paracetamol. It has an unknown cause and therefore potentially under-diagnosed, to be considered in the same way as the other more frequent etiologies. Because of this lack of knowledge, its frequency is probably underestimated considering the widespread consumption of paracetamol in the population.
    MeSH term(s) Acetaminophen ; Acid-Base Equilibrium ; Acidosis/chemically induced ; Humans ; Iatrogenic Disease ; Pyrrolidonecarboxylic Acid/metabolism
    Chemical Substances Acetaminophen (362O9ITL9D) ; Pyrrolidonecarboxylic Acid (SZB83O1W42)
    Language French
    Publishing date 2021-08-06
    Publishing country Belgium
    Document type Case Reports
    ZDB-ID 414001-1
    ISSN 0370-629X ; 0035-3663
    ISSN 0370-629X ; 0035-3663
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    Zs.A 597: Show issues Location:
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  3. Article ; Online: Ignorance is bliss? Information and risk on crowdfunding platforms.

    D'Arcangelo, Chiara / Morreale, Azzurra / Mittone, Luigi / Collan, Mikael

    PloS one

    2023  Volume 18, Issue 6, Page(s) e0286876

    Abstract: This research examines the determinants of project success on crowdfunding platforms within a competitive context. We focus on the specific horizontal attributes of the project-attributes that do not affect the project returns but over which investors ... ...

    Abstract This research examines the determinants of project success on crowdfunding platforms within a competitive context. We focus on the specific horizontal attributes of the project-attributes that do not affect the project returns but over which investors may have heterogeneous preferences-and on the project returns' risk level. We run a laboratory experiment with several set-ups, where multiple projects compete for funding simultaneously and where potential investors operate in a quasi-continuous time. We find the horizontal attributes' information affects project selection, while the risk level of the project returns affects the amount of collected funding.
    MeSH term(s) Fund Raising ; Laboratories ; Crowdsourcing
    Language English
    Publishing date 2023-06-16
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0286876
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  4. Article: The treatment of gastroesophageal reflux disease with proton-pump inhibitors and its implications on managed care--pharmacoeconomics and its application to antisecretory drugs: a case study.

    Morreale, A

    Managed care interface

    2001  Volume Suppl B, Page(s) 28–30; discussion 31–3

    MeSH term(s) 2-Pyridinylmethylsulfinylbenzimidazoles ; Anti-Ulcer Agents/economics ; Anti-Ulcer Agents/therapeutic use ; California ; Clinical Trials as Topic ; Enzyme Inhibitors/economics ; Enzyme Inhibitors/therapeutic use ; Gastroesophageal Reflux/drug therapy ; Humans ; Lansoprazole ; Managed Care Programs ; Omeprazole/analogs & derivatives ; Omeprazole/economics ; Omeprazole/therapeutic use ; Organizational Case Studies ; Patient Satisfaction ; Proton Pump Inhibitors ; Quality of Life ; Randomized Controlled Trials as Topic ; United States ; United States Department of Veterans Affairs
    Chemical Substances 2-Pyridinylmethylsulfinylbenzimidazoles ; Anti-Ulcer Agents ; Enzyme Inhibitors ; Proton Pump Inhibitors ; Lansoprazole (0K5C5T2QPG) ; Omeprazole (KG60484QX9)
    Language English
    Publishing date 2001
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2086819-4
    ISSN 1096-5645
    ISSN 1096-5645
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5709: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  5. Article ; Online: Increasing access to care using clinical pharmacy specialist providers in outpatient mental health: Successful practice integration within the Department of Veterans Affairs.

    Moore, Tera / Groppi, Julie / Ourth, Heather / Morreale, Anthony / Torrise, Virginia

    Journal of the American Pharmacists Association : JAPhA

    2020  Volume 60, Issue 5S, Page(s) S107–S112

    Abstract: Background: To highlight the role and impact of the mental health (MH) clinical pharmacist provider in outpatient MH through successful practice integration into team-based care.: Objective: The MH clinical pharmacy specialist (CPS) provider serves ... ...

    Abstract Background: To highlight the role and impact of the mental health (MH) clinical pharmacist provider in outpatient MH through successful practice integration into team-based care.
    Objective: The MH clinical pharmacy specialist (CPS) provider serves in many key roles to improve patient-centered care and medication outcomes by supporting the needs of the MH team, patients, and caregivers in areas of comprehensive medication management. MH CPS providers are integrated as MH providers in general and specialty MH clinics, behavioral health clinics embedded in primary care, residential rehabilitation facilities, specialty MH programs, and in inpatient MH units to improve access, quality, and safety.
    Practice description: There is a shortage of psychiatrists across the United States, which affects the ability to provide MH care to patients.
    Practice innovation: There is a need to transform the MH team to include clinicians focused on providing services to the growing population with MH conditions; hence, the expertise of the MH CPS is an asset to increase access to comprehensive medication management services.
    Evaluation: The MH CPS provider serves patients with a variety of MH conditions, managing medication-related adverse events, performing ongoing and acute medication monitoring, and collaborating with other health care providers for management of new diagnoses.
    Results: The MH CPS provider improves access to care, clinical outcomes, and safety when deployed as direct patient care providers on Veterans Affairs (VA) interprofessional care teams. VA MH clinical pharmacy practice continues to demonstrate what the MH CPS provider, practicing at the top of their license, can achieve as a core member in MH team-based care.
    Conclusion: These foundational concepts can be applied to further expand MH clinical pharmacy practice into non-VA settings through the use collaborative practice agreements and integration into interprofessional care teams, providing access to patients in need of MH care.
    MeSH term(s) Health Services Accessibility ; Humans ; Mental Health ; Outpatients ; Pharmacy ; United States ; United States Department of Veterans Affairs ; Veterans
    Language English
    Publishing date 2020-04-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2118585-2
    ISSN 1544-3450 ; 1544-3191 ; 1086-5802
    ISSN (online) 1544-3450
    ISSN 1544-3191 ; 1086-5802
    DOI 10.1016/j.japh.2020.03.011
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    Zs.A 1042: Show issues Location:
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  6. Article ; Online: Perceptions of clinical pharmacy specialists' contributions in mental health clinical teams.

    Gillespie, Chris / Kleinberg, Felicia / Zogas, Anna / Morreale, Anthony / Ourth, Heather / Tran, Michael / Moore, Tera / Miller, Donald / McCullough, Megan

    The mental health clinician

    2022  Volume 12, Issue 1, Page(s) 15–22

    Abstract: Introduction: Mental health (MH) clinical pharmacy specialists (CPS) are increasingly functioning as integral providers in MH care teams. MH providers may delegate many medication management tasks to the CPS. As there is a shortage of primary care and ... ...

    Abstract Introduction: Mental health (MH) clinical pharmacy specialists (CPS) are increasingly functioning as integral providers in MH care teams. MH providers may delegate many medication management tasks to the CPS. As there is a shortage of primary care and specialist MH providers, CPS are increasingly being utilized in MH care clinics. We assess provider and CPS perceptions of the contributions of CPS to MH clinical teams in the Veterans Health Administration.
    Methods: We examined the roles and functions of CPS in MH clinics through surveys (n = 374) and semistructured interviews (n = 16) with MH CPS and other members of MH clinical teams (psychiatrists, nurse practitioners, registered nurses, social workers) to gain insight into how CPS were integrated in these settings. We assessed perceptions of CPS contributions to MH teams, interactions between CPS and other providers, and challenges of integrating CPS into MH clinical teams.
    Results: Contributions of CPS in MH were received positively by clinical team members. Clinical pharmacy specialists providing comprehensive medication management were especially valuable in the management of clozapine. The knowledge and training of CPS reassured providers who frequently referred to them with questions about medication and medication therapy management. MH CPS were also perceived to be received well by patients.
    Discussion: The integration of MH CPS into MH teams was well received by team members and patients alike. The MH CPS have become important members of the MH team and are widely viewed as being able to improve access, quality, and workflow.
    Language English
    Publishing date 2022-01-21
    Publishing country United States
    Document type Journal Article
    ISSN 2168-9709
    ISSN (online) 2168-9709
    DOI 10.9740/mhc.2022.01.015
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  7. Article ; Online: Distinct binding of cetirizine enantiomers to human serum albumin and the human histamine receptor H

    Perona, Almudena / Ros, M Piedad / Mills, Alberto / Morreale, Antonio / Gago, Federico

    Journal of computer-aided molecular design

    2020  Volume 34, Issue 10, Page(s) 1045–1062

    Abstract: Cetirizine, a major metabolite of hydroxyzine, became a marketed second-generation ... ...

    Abstract Cetirizine, a major metabolite of hydroxyzine, became a marketed second-generation H
    MeSH term(s) Animals ; Binding Sites ; Cetirizine/chemistry ; Cetirizine/metabolism ; Histamine H1 Antagonists, Non-Sedating/chemistry ; Histamine H1 Antagonists, Non-Sedating/metabolism ; Horses ; Humans ; Protein Binding ; Receptors, Histamine/metabolism ; Serum Albumin/metabolism ; Serum Albumin, Human/metabolism ; Stereoisomerism
    Chemical Substances Histamine H1 Antagonists, Non-Sedating ; Receptors, Histamine ; Serum Albumin ; Cetirizine (YO7261ME24) ; Serum Albumin, Human (ZIF514RVZR)
    Language English
    Publishing date 2020-06-23
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 808166-9
    ISSN 1573-4951 ; 0920-654X
    ISSN (online) 1573-4951
    ISSN 0920-654X
    DOI 10.1007/s10822-020-00328-8
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    Zs.A 2625: Show issues Location:
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  8. Article ; Online: Clinical pharmacy practitioners' semi-visible labor: building referral relationships in interprofessional collaborative care.

    Zogas, Anna / Gillespie, Chris / Kleinberg, Felicia / Reisman, Joel / Ndiwane, Ndindam / Tran, Michael / Ourth, Heather / Morreale, Anthony / Miller, Donald / McCullough, Megan

    Journal of interprofessional care

    2023  Volume 37, Issue 5, Page(s) 698–705

    Abstract: Clinical pharmacy practitioners (CPP) in the Veterans Health Administration (VHA) prescribe medications and help manage chronic conditions such as diabetes, and they are increasingly working as part of interprofessional clinical teams. The challenges of ... ...

    Abstract Clinical pharmacy practitioners (CPP) in the Veterans Health Administration (VHA) prescribe medications and help manage chronic conditions such as diabetes, and they are increasingly working as part of interprofessional clinical teams. The challenges of integrating a new role in a clinical team are documented, but we know less about strategies new healthcare providers use to overcome these challenges. We studied how clinical pharmacy practitioners integrated into clinical teams. We conducted telephone interviews with clinical pharmacy practitioners (
    MeSH term(s) Humans ; Patient Care Team ; Attitude of Health Personnel ; Interprofessional Relations ; Referral and Consultation ; Pharmacy
    Language English
    Publishing date 2023-01-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 1099758-1
    ISSN 1469-9567 ; 0884-3988 ; 1356-1820
    ISSN (online) 1469-9567
    ISSN 0884-3988 ; 1356-1820
    DOI 10.1080/13561820.2023.2169665
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  9. Article: Binding of non-canonical peptidoglycan controls

    Espaillat, Akbar / Carrasco-López, Cesar / Bernardo-García, Noelia / Rojas-Altuve, Alzoray / Klett, Javier / Morreale, Antonio / Hermoso, Juan A / Cava, Felipe

    Computational and structural biotechnology journal

    2021  Volume 19, Page(s) 1119–1126

    Abstract: Broad-spectrum amino acid racemases (Bsrs) enable bacteria to generate non-canonical D-amino acids (NCDAAs), whose roles and impact on microbial physiology, including modulation of cell wall structure and dissolution of biofilms, are just beginning to be ...

    Abstract Broad-spectrum amino acid racemases (Bsrs) enable bacteria to generate non-canonical D-amino acids (NCDAAs), whose roles and impact on microbial physiology, including modulation of cell wall structure and dissolution of biofilms, are just beginning to be appreciated. Here we used a diverse array of structural, biochemical and molecular simulation studies to define and characterize how BsrV is post-translationally regulated. We discovered that contrary to
    Language English
    Publishing date 2021-01-26
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2001-0370
    ISSN 2001-0370
    DOI 10.1016/j.csbj.2021.01.031
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  10. Article ; Online: When a Nontuberculous Mycobacterial Infection Reveals an Error of Immunity: A Single Center's Experience.

    Morreale, Alessia / Dotta, Laura / Vairo, Donatella / Bazzana, Tullia / Lougaris, Vassilios / Soresina, Annarosa / Plebani, Alessandro / Giliani, Silvia Clara / Porta, Fulvio / Matteelli, Alberto / Redaelli De Zinis, Luca Oscar / Badolato, Raffaele

    The Pediatric infectious disease journal

    2022  Volume 41, Issue 5, Page(s) 427–429

    Abstract: We present an algorithm that may be applied in case of a diagnosis of pediatric nontuberculous mycobacterial disease to identify the patients who may require an immunologic assessment to discover a possible underlying immune system defect predisposing to ...

    Abstract We present an algorithm that may be applied in case of a diagnosis of pediatric nontuberculous mycobacterial disease to identify the patients who may require an immunologic assessment to discover a possible underlying immune system defect predisposing to their nontuberculous mycobacterial infections.
    MeSH term(s) Child ; Humans ; Mycobacterium Infections, Nontuberculous/diagnosis ; Mycobacterium Infections, Nontuberculous/microbiology ; Nontuberculous Mycobacteria
    Language English
    Publishing date 2022-01-27
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/INF.0000000000003461
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