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  1. Book: Approaches to quality management and accreditation in a genetic testing laboratory

    Berwouts, Sarah / Morris, Michael A. / Dequeker, Elisabeth

    (European journal of human genetics ; 18, Suppl. 1)

    2010  

    Author's details Sarah Berwouts ; Michael A. Morris and Elisabeth Dequeker
    Series title European journal of human genetics ; 18, Suppl. 1
    Collection
    Language English
    Size S19 S. : Ill.
    Publisher Nature Publ. Group
    Publishing place London
    Publishing country United States
    Document type Book
    HBZ-ID HT016509703
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 3589 -18,Suppl.1- not available for loan Zeitschriften-Lesesaal

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  2. Article: Green Nanofabrication Opportunities in the Semiconductor Industry: A Life Cycle Perspective.

    Mullen, Eleanor / Morris, Michael A

    Nanomaterials (Basel, Switzerland)

    2021  Volume 11, Issue 5

    Abstract: The turn of the 21st century heralded in the semiconductor age alongside the Anthropocene epoch, characterised by the ever-increasing human impact on the environment. The ecological consequences of semiconductor chip manufacturing are the most ... ...

    Abstract The turn of the 21st century heralded in the semiconductor age alongside the Anthropocene epoch, characterised by the ever-increasing human impact on the environment. The ecological consequences of semiconductor chip manufacturing are the most predominant within the electronics industry. This is due to current reliance upon large amounts of solvents, acids and gases that have numerous toxicological impacts. Management and assessment of hazardous chemicals is complicated by trade secrets and continual rapid change in the electronic manufacturing process. Of the many subprocesses involved in chip manufacturing, lithographic processes are of particular concern. Current developments in bottom-up lithography, such as directed self-assembly (DSA) of block copolymers (BCPs), are being considered as a next-generation technology for semiconductor chip production. These nanofabrication techniques present a novel opportunity for improving the sustainability of lithography by reducing the number of processing steps, energy and chemical waste products involved. At present, to the extent of our knowledge, there is no published life cycle assessment (LCA) evaluating the environmental impact of new bottom-up lithography versus conventional lithographic techniques. Quantification of this impact is central to verifying whether these new nanofabrication routes can replace conventional deposition techniques in industry as a more environmentally friendly option.
    Language English
    Publishing date 2021-04-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano11051085
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Synthesis and application of fluorescent teixobactin analogs.

    Morris, Michael A / Jones, Chelsea R / Nowick, James S

    Methods in enzymology

    2022  Volume 665, Page(s) 233–258

    Abstract: Teixobactin is a promising new antibiotic that kills a spectrum of Gram-positive pathogens that are considered to be urgent threats by the CDC and the WHO. Better understanding of the novel mechanism of action of teixobactin may assist in developing new ... ...

    Abstract Teixobactin is a promising new antibiotic that kills a spectrum of Gram-positive pathogens that are considered to be urgent threats by the CDC and the WHO. Better understanding of the novel mechanism of action of teixobactin may assist in developing new antibiotics and furthering our understanding of antibiotic resistance. This chapter describes the synthesis and application of fluorescent teixobactin analogs in fluorescence microscopy to study the mode of action of teixobactin. The first part of this chapter describes the synthesis and purification of fluorescent teixobactin analogs using two synthetic approaches. The second part of this chapter describes the application of the fluorescent teixobactin analogs to visualize their interactions with molecular targets in B. subtilis using fluorescence microscopy. The methods described herein provide synthetic access to chemical probes that may help further the understanding of antibiotic resistance.
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Depsipeptides/chemistry ; Depsipeptides/pharmacology ; Microscopy, Fluorescence
    Chemical Substances Anti-Bacterial Agents ; Depsipeptides ; teixobactin (LC730GUE72)
    Language English
    Publishing date 2022-01-20
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ISSN 1557-7988
    ISSN (online) 1557-7988
    DOI 10.1016/bs.mie.2021.12.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Fabrication of Dimensional and Structural Controlled Open Pore, Mesoporous Silica Topographies on a Substrate.

    Ghoshal, Tandra / Thorat, Atul / Prochukhan, Nadezda / Morris, Michael A

    Nanomaterials (Basel, Switzerland)

    2022  Volume 12, Issue 13

    Abstract: Open pore mesoporous silica (MPS) thin films and channels were prepared on a substrate surface. The pore dimension, thickness and ordering of the MPS thin films were controlled by using different concentrations of the precursor and molecular weight of ... ...

    Abstract Open pore mesoporous silica (MPS) thin films and channels were prepared on a substrate surface. The pore dimension, thickness and ordering of the MPS thin films were controlled by using different concentrations of the precursor and molecular weight of the pluronics. Spectroscopic and microscopic techniques were utilized to determine the alignment and ordering of the pores. Further, MPS channels on a substrate surface were fabricated using commercial available lithographic etch masks followed by an inductively coupled plasma (ICP) etch. Attempts were made to shrink the channel dimension by using a block copolymer (BCP) hard mask methodology. In this regard, polystyrene-
    Language English
    Publishing date 2022-06-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano12132223
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  5. Article ; Online: Sub-25 nm Inorganic and Dielectric Nanopattern Arrays on Substrates: A Block Copolymer-Assisted Lithography.

    Ghoshal, Tandra / Prochukhan, Nadezda / Morris, Michael A

    ACS omega

    2021  Volume 6, Issue 51, Page(s) 35738–35744

    Abstract: A range of well-ordered inorganic (antimony, tin, and tungsten oxide) and dielectric (silica, alumina, and hafnia) nanoparticles and nanowire array patterns are created on substrates by a low-cost block copolymer (BCP) approach. A cylindrical-phase PS- ...

    Abstract A range of well-ordered inorganic (antimony, tin, and tungsten oxide) and dielectric (silica, alumina, and hafnia) nanoparticles and nanowire array patterns are created on substrates by a low-cost block copolymer (BCP) approach. A cylindrical-phase PS-
    Language English
    Publishing date 2021-12-16
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.1c05124
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Direct Laser Writing of Silica Nanoparticle Nanocomposites: Probing Mechanical Reinforcement and Understanding Structural Color from Design Parameters.

    Augustine, Amrutha / Qian, Jing / Faraone, Teodora / Kolagatla, Srikanth / Prochukhan, Nadezda / Morris, Michael A / Bradley, A Louise / Florea, Larisa / Delaney, Colm

    Small (Weinheim an der Bergstrasse, Germany)

    2024  , Page(s) e2310058

    Abstract: Nanocomposite materials have been thoroughly exploited in additive manufacturing, as a means to alter physical, chemical, and optical properties of resulting structures. Herein, nanocomposite materials suitable for direct laser writing (DLW) by two- ... ...

    Abstract Nanocomposite materials have been thoroughly exploited in additive manufacturing, as a means to alter physical, chemical, and optical properties of resulting structures. Herein, nanocomposite materials suitable for direct laser writing (DLW) by two-photon polymerization are presented. These materials, comprising silica nanoparticles, bring significant added value to the technology through physical reinforcement and controllable photonic properties. Incorporation into acrylate photoresists, via a one-step fabrication process, enables the formation of complex structures with large overhangs. The inclusion of 150 nm silica nanoparticles in DLW photoresists at high concentrations, allows for the fabrication of composite microstructures that show reflected color, a product of the relative contributions from the quasi-ordering and random scattering. Using common DLW design parameters, such as slicing distance and structure dimension, a wide gamut of structural color, in solution, using a set concentration of nanoparticles is demonstrated. Numerical modeling is employed to predict the reflected wavelength of the pixel arrays, across the visible spectrum, and this information is used to encode reflected colors into different pixel arrays.
    Language English
    Publishing date 2024-03-05
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2168935-0
    ISSN 1613-6829 ; 1613-6810
    ISSN (online) 1613-6829
    ISSN 1613-6810
    DOI 10.1002/smll.202310058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Development and application of a 3D image analysis strategy for focused ion beam - Scanning electron microscopy tomography of porous soft materials.

    Prochukhan, Nadezda / Rafferty, Aran / Canavan, Megan / Daly, Dermot / Selkirk, Andrew / Rameshkumar, Saranya / Morris, Michael A

    Microscopy research and technique

    2024  Volume 87, Issue 6, Page(s) 1335–1347

    Abstract: In recent years, the potential of porous soft materials in various device technologies has increased in importance due to applications in fields, such as wearable electronics, medicine, and transient devices. However, understanding the 3-dimensional ... ...

    Abstract In recent years, the potential of porous soft materials in various device technologies has increased in importance due to applications in fields, such as wearable electronics, medicine, and transient devices. However, understanding the 3-dimensional architecture of porous soft materials at the microscale remains a challenge. Herein, we present a method to structurally analyze soft materials using Focused Ion Beam - Scanning Electron Microscopy (FIB-SEM) tomography. Two materials, polymethyl methacrylate (PMMA) membrane and pine wood veneer were chosen as test-cases. FIB-SEM was successfully used to reconstruct the true topography of these materials in 3D. Structural and physical properties were subsequently deduced from the rendered 3D models. The methodology used segmentation, coupled with optimized thresholding, image processing, and reconstruction protocols. The 3D models generated pore size distribution, pore inter-connectivity, tortuosity, thickness, and curvature data. It was shown that FIB-SEM tomography provides both an informative and visual depiction of structure. To evaluate and validate the FIB-SEM reconstructions, porous properties were generated from the physical property analysis techniques, gas adsorption analysis using Brunauer-Emmett-Teller (BET) surface area analysis and mercury intrusion porosimetry (MIP) analysis. In general, the data obtained from the FIB-SEM reconstructions was well-matched with the physical data. RESEARCH HIGHLIGHTS: Porous specimens of both synthetic and biological nature, a poly(methyl methacrylate) membrane and a pine veneer respectively, are reconstructed via FIB-SEM tomography without resin-embedding. Different thresholding and reconstruction methods are explored whereby shadowing artifacts are present with the aid of free open-source software. Reconstruction data is compared to physical data: MIP, gas adsorption isotherms which are analyzed via BET and Barrett-Joyner-Halenda (BJH) analysis to yield a full picture of the materials.
    Language English
    Publishing date 2024-02-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1099714-3
    ISSN 1097-0029 ; 1059-910X
    ISSN (online) 1097-0029
    ISSN 1059-910X
    DOI 10.1002/jemt.24514
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2251: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Book: Therapeutic exercise

    Bandy, William D. / Sanders, Barbara / Morris, Michael A.

    techniques for intervention

    2001  

    Author's details William D. Bandy ; Barbara Sanders. Photogr. by Michael A. Morris
    Keywords Musculoskeletal Diseases / therapy ; Exercise Therapy / methods
    Language English
    Size VIII, 386 S. : überw. Ill.
    Publisher Lippincott William & Wilkins
    Publishing place Baltimore, Md. u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT013385305
    ISBN 0-7817-2130-X ; 978-0-7817-2130-1
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2003 A 2401 order for loan Magazin

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  9. Article ; Online: Biocircularity: a Framework to Define Sustainable, Circular Bioeconomy.

    Holden, Nicholas M / Neill, Andrew M / Stout, Jane C / O'Brien, Derek / Morris, Michael A

    Circular economy and sustainability

    2022  Volume 3, Issue 1, Page(s) 77–91

    Abstract: Bioeconomy is proposed as a solution to reduce reliance on fossil resources. However, bioeconomy is not always inherently circular and can mimic the conventional take, make, consume, dispose linear economic model. Agricultural systems will be relied on ... ...

    Abstract Bioeconomy is proposed as a solution to reduce reliance on fossil resources. However, bioeconomy is not always inherently circular and can mimic the conventional take, make, consume, dispose linear economic model. Agricultural systems will be relied on to provide food, materials, and energy, so unless action is taken, demand for land will inevitably exceed supply. Bioeconomy will have to embrace circularity to enable production of renewable feedstocks in terms of both biomass yield and maintaining essential natural capital. The concept of biocircularity is proposed as an integrated systems approach to the sustainable production of renewable biological materials focusing on extended use, maximum reuse, recycling, and design for degradation from polymers to monomers, while avoiding the "failure" of end of life and minimizing energy demand and waste. Challenges are discussed including sustainable production and consumption; quantifying externalities; decoupling economic growth from depletion; valuing natural ecosystems; design across scales; renewable energy provision; barriers to adoption; and integration with food systems. Biocircularity offers a theoretical basis and measures of success, for implementing sustainable circular bioeconomy.
    Language English
    Publishing date 2022-06-08
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2730-5988
    ISSN (online) 2730-5988
    DOI 10.1007/s43615-022-00180-y
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  10. Article: Fabrication and Evaluation of Filtration Membranes from Industrial Polymer Waste.

    Bano, Saleheen / Pednekar, Mukesh / Rameshkumar, Saranya / Borah, Dipu / Morris, Michael A / Padamati, Ramesh Babu / Cronly, Niamh

    Membranes

    2023  Volume 13, Issue 4

    Abstract: Polyvinylidene fluoride (PVDF) polymers are known for their diverse range of industrial applications and are considered important raw materials for membrane manufacturing. In view of circularity and resource efficiency, the present work mainly deals with ...

    Abstract Polyvinylidene fluoride (PVDF) polymers are known for their diverse range of industrial applications and are considered important raw materials for membrane manufacturing. In view of circularity and resource efficiency, the present work mainly deals with the reusability of waste polymer 'gels' produced during the manufacturing of PVDF membranes. Herein, solidified PVDF gels were first prepared from polymer solutions as model waste gels, which were then subsequently used to prepare membranes via the phase inversion process. The structural analysis of fabricated membranes confirmed the retention of molecular integrity even after reprocessing, whereas the morphological analysis showed a symmetric bi-continuous porous structure. The filtration performance of membranes fabricated from waste gels was studied in a crossflow assembly. The results demonstrate the feasibility of gel-derived membranes as potential microfiltration membranes exhibiting a pure water flux of 478 LMH with a mean pore size of ~0.2 µm. To further evaluate industrial applicability, the performance of the membranes was tested in the clarification of industrial wastewater, and the membranes showed good recyclability with about 52% flux recovery. The performance of gel-derived membranes thus demonstrates the recycling of waste polymer gels for improving the sustainability of membrane fabrication processes.
    Language English
    Publishing date 2023-04-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2614641-1
    ISSN 2077-0375
    ISSN 2077-0375
    DOI 10.3390/membranes13040445
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