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  1. Article: Evaluation of Incise Drape Lift Using 2% Chlorhexidine Gluconate/70% Isopropyl Alcohol Preoperative Skin Preparations in a Human Volunteer Knee Model.

    Olson, Linda K / Morse, Dan J / Paulson, Joan E / Bernatchez, Stéphanie F

    Arthroplasty today

    2022  Volume 15, Page(s) 24–28

    Abstract: Background: Before surgery, skin is prepped with antiseptics to reduce risk of surgical site infections. An incise drape can be used as an additional modality to immobilize any remaining bacteria. Good adhesion of this drape is critical for infection ... ...

    Abstract Background: Before surgery, skin is prepped with antiseptics to reduce risk of surgical site infections. An incise drape can be used as an additional modality to immobilize any remaining bacteria. Good adhesion of this drape is critical for infection prevention.
    Methods: This is a randomized controlled study using a human volunteer knee model (n = 30) to evaluate the adhesion performance of an incise drape comparing 2 skin preparations. A new investigational 2% chlorhexidine gluconate/70% isopropyl alcohol skin prep (prep A) was compared with an existing skin prep containing the same active agents (prep B). Two samples of an iodine-impregnated incise drape were placed on each knee after prepping. Knees were flexed in dry conditions, under a saline-soaked gauze, and after saline lavage. The frequency of drape lift was recorded after each challenge.
    Results: After dry flex, 4 of 60 samples (6.7%) had lifted on prep A and 0 on prep B (
    Conclusions: Prep A resulted in reduced frequency of incise drape lift from skin under wet conditions in this model compared with prep B.
    Language English
    Publishing date 2022-03-27
    Publishing country United States
    Document type Journal Article
    ISSN 2352-3441
    ISSN 2352-3441
    DOI 10.1016/j.artd.2022.02.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A Comparison of Electronic and Traditional Stethoscopes in the Heart Auscultation of Obese Patients

    Kalinauskienė, Eglė / Razvadauskas, Haroldas / Morse, Dan J / Maxey, Gail E / Naudžiūnas, Albinas

    Medicina (Kaunas, Lithuania)

    2019  Volume 55, Issue 4

    Abstract: Background and objectives: ...

    Abstract Background and objectives:
    MeSH term(s) Age Factors ; Aged ; Aged, 80 and over ; Body Mass Index ; Cardiologists ; Echocardiography ; Female ; Hearing Loss, High-Frequency ; Heart Auscultation/instrumentation ; Heart Murmurs/complications ; Heart Murmurs/diagnosis ; Humans ; Male ; Middle Aged ; Obesity/complications ; Obesity/physiopathology ; Sensitivity and Specificity ; Stethoscopes
    Language English
    Publishing date 2019-04-05
    Publishing country Switzerland
    Document type Comparative Study ; Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina55040094
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6270: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: How to better monitor and clean irregular surfaces in operating rooms: Insights gained by using both ATP luminescence and RODAC assays.

    Ellis, Olivia / Godwin, Hilary / David, Maren / Morse, Dan J / Humphries, Romney / Uslan, Daniel Z

    American journal of infection control

    2018  Volume 46, Issue 8, Page(s) 906–912

    Abstract: Background: A major limitation to developing evidence-based approaches to infection prevention is the paucity of real-time, quantitative methods for monitoring the cleanliness of environmental surfaces in clinical settings. One solution that has been ... ...

    Abstract Background: A major limitation to developing evidence-based approaches to infection prevention is the paucity of real-time, quantitative methods for monitoring the cleanliness of environmental surfaces in clinical settings. One solution that has been proposed is adenosine triphosphate (ATP) bioluminescence assays, but this method does not provide information about the source of the ATP.
    Materials/methods: To address this gap, we conducted a study in which ATP bioluminescence was coupled with traditional RODAC sampling and matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry to assess which organisms were viable and present. Using this mixed assessment approach, we evaluated cleaning of 5 different types of high-touch surfaces (overhead lights, door handles, anesthesia keyboards, mattresses, and side tables) in operating rooms.
    Results: Whether surfaces tested cleaner after turnaround than they did before turnaround depended on the surface type. Before and after cleaning, flat, covered surfaces (mattresses and side tables) were more likely to pass as "clean" by ATP assay than uncovered, irregularly shaped surfaces (overhead lights, door handles, and anesthesia keyboards). Irregularly shaped surfaces were more likely to pass by RODAC assay than by ATP assay after cleaning.
    Conclusion: Our results suggest that irregularly shaped surfaces in operating rooms may require enhanced covering, cleaning, and monitoring protocols compared to more regularly shaped surfaces.
    MeSH term(s) Adenosine Triphosphate/analysis ; Decontamination/methods ; Disinfection/methods ; Environmental Microbiology ; Environmental Monitoring/methods ; Humans ; Luminescent Measurements/methods ; Microbiological Techniques/methods ; Operating Rooms ; Quality Assurance, Health Care/methods ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
    Chemical Substances Adenosine Triphosphate (8L70Q75FXE)
    Language English
    Publishing date 2018-05-18
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 392362-9
    ISSN 1527-3296 ; 0196-6553
    ISSN (online) 1527-3296
    ISSN 0196-6553
    DOI 10.1016/j.ajic.2018.03.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1773: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Effect of preoperative warming on intraoperative hypothermia: a randomized-controlled trial.

    Lau, Aaron / Lowlaavar, Nasim / Cooke, Erin M / West, Nicholas / German, Alexandra / Morse, Dan J / Görges, Matthias / Merchant, Richard N

    Canadian journal of anaesthesia = Journal canadien d'anesthesie

    2018  Volume 65, Issue 9, Page(s) 1029–1040

    Abstract: Purpose: The purpose of this study was to evaluate the effects of preoperative forced-air warming on intraoperative hypothermia.: Methods: In this randomized-controlled trial, adult patients scheduled for elective, non-cardiac surgery under general ... ...

    Title translation Effet du réchauffement préopératoire sur l’hypothermie peropératoire: essai randomisé contrôlé.
    Abstract Purpose: The purpose of this study was to evaluate the effects of preoperative forced-air warming on intraoperative hypothermia.
    Methods: In this randomized-controlled trial, adult patients scheduled for elective, non-cardiac surgery under general anesthesia were stratified by scheduled surgical duration (< 2.5 hr or ≥ 2.5 hr) and then randomized to a pre-warming group using a BairPaws™ forced-air warming system for at least 30 min preoperatively or to a control group with warmed blankets on request. All patients were warmed intraoperatively via convective forced-air warming blankets. Perioperative temperature was measured using the SpotOn™ temperature system consisting of a single-use disposable sensor applied to the participant's forehead. The primary outcome was the magnitude of intraoperative hypothermia calculated as the area under the time-temperature curve for core temperatures < 36°C between induction of general anesthesia and leaving the operating room. Secondary outcomes included surgical site infections, packed red blood cell requirements, and 24 hr postoperative opioid consumption.
    Results: Two hundred participants were analyzed (101 control; 99 pre-warmed). Pre-warmed participants had a lower median [interquartile range] magnitude of hypothermia than controls (0.00 [0.00-0.12] °C·hr
    Conclusion: A minimum of 30 min of preoperative forced-air convective warming decreased the overall intraoperative hypothermic exposure. While redistribution hypothermia still occurs despite pre- and intraoperative forced-air warming, their combined application results in greater preservation of intraoperative normothermia compared with intraoperative forced-air warming alone.
    Trial registration: www.clinicaltrials.gov (NCT02177903). Registered 25 June 2014.
    MeSH term(s) Aged ; Female ; Hot Temperature ; Humans ; Hypothermia/prevention & control ; Intraoperative Complications/prevention & control ; Male ; Middle Aged ; Outcome Assessment (Health Care) ; Preoperative Care
    Language English
    Publishing date 2018-06-05
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 91002-8
    ISSN 1496-8975 ; 0832-610X
    ISSN (online) 1496-8975
    ISSN 0832-610X
    DOI 10.1007/s12630-018-1161-8
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 109: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Prospective, randomized in vivo comparison of a dual-active waterless antiseptic versus two alcohol-only waterless antiseptics for surgical hand antisepsis.

    Olson, Linda K M / Morse, Dan J / Duley, Collette / Savell, Brenon K

    American journal of infection control

    2012  Volume 40, Issue 2, Page(s) 155–159

    Abstract: Background: This study aimed to demonstrate the value of adding an active level of a persistent antimicrobial agent, such as chlorhexidine gluconate (CHG), to an alcohol-based surgical hand antiseptic.: Methods: The persistence of 3 waterless, ... ...

    Abstract Background: This study aimed to demonstrate the value of adding an active level of a persistent antimicrobial agent, such as chlorhexidine gluconate (CHG), to an alcohol-based surgical hand antiseptic.
    Methods: The persistence of 3 waterless, brushless alcohol-based surgical hand antiseptics, including one product containing CHG, was compared. The test products were applied a total of 12 times over 5 days. Samples of aerobic bacteria were collected on days 1 and 5, on both days immediately after drying and 6 hours later, using the glove juice technique. Relative suppression of regrowth was compared using t tests.
    Results: Using an equivalence margin of 20%, the alcohol plus CHG product showed noninferiority to the alcohol-only products at all sampling points and, based on significantly lower bacterial regrowth (P = .026), superior persistence to the alcohol-only products after 6 hours of glove wear.
    Conclusions: Given the primary objective of surgical hand antisepsis of reducing resident skin flora for the duration of the surgical procedure, using an alcohol-based hand antiseptic containing CHG appears to be the most appropriate choice for maintaining microbial levels as low as possible for as long as possible.
    MeSH term(s) Adolescent ; Adult ; Alcohols/pharmacology ; Anti-Infective Agents, Local/pharmacology ; Antisepsis/methods ; Bacteria, Aerobic/drug effects ; Chlorhexidine/analogs & derivatives ; Chlorhexidine/pharmacology ; Colony Count, Microbial ; Female ; Gloves, Surgical/microbiology ; Hand/microbiology ; Hand Disinfection/methods ; Humans ; Male ; Middle Aged ; Prospective Studies ; Skin/microbiology
    Chemical Substances Alcohols ; Anti-Infective Agents, Local ; chlorhexidine gluconate (MOR84MUD8E) ; Chlorhexidine (R4KO0DY52L)
    Language English
    Publishing date 2012-03
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 392362-9
    ISSN 1527-3296 ; 0196-6553
    ISSN (online) 1527-3296
    ISSN 0196-6553
    DOI 10.1016/j.ajic.2011.10.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1773: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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