LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 87

Search options

  1. Article: Technical Innovations to Reduce Complication Rates in Esophageal Atresia with Particular Reference to Long-term Outcomes: A Single Surgeon's Experience of 22 Years.

    Morsi, Ahmed / Misra, Devesh

    Journal of Indian Association of Pediatric Surgeons

    2022  Volume 27, Issue 6, Page(s) 728–734

    Abstract: Background: Following esophageal atresia/tracheoesophageal fistula (EA/TEF) repair, the standard leak rate reported in the literature is 5%-10%, and stricture rate is 40%-72%. There is a global quest for surgical innovations to drive down these ... ...

    Abstract Background: Following esophageal atresia/tracheoesophageal fistula (EA/TEF) repair, the standard leak rate reported in the literature is 5%-10%, and stricture rate is 40%-72%. There is a global quest for surgical innovations to drive down these complication rates which can cause considerable morbidity.
    Methods: A prospectively maintained database of the senior author's patients who had esophageal atresia repair from 1995 to 2016 was reviewed. Two distinct innovations were implemented: (1) adequate or generous mobilization of the lower esophageal pouch and (2) a 2-5 mm slit in distal esophagus to widen its circumference.
    Results: Forty-three patients with EA/TEF were reviewed. Of those, 40 underwent primary repair. The median follow-up was 12.5 years (range 4-26 years). There were no anastomotic leaks and only 8 (20%) patients developed anastomotic strictures requiring dilations (1-5 dilations/patients). One patient (2.5%) had a recurrent fistula. One early mortality was recorded. At the latest follow-up, 35 (87.5%) patients had normal oral feeding, while 1 (2.5%) patient had occasional food sticking episodes. Four syndromic patients (10%) were on jejunal or gastrostomy feeding.
    Conclusion: An adequate or generous mobilization of the distal esophageal pouch, together with a 2-5 mm slit in the distal esophagus, achieves a tension-free and wide anastomosis. All anastomoses eventually narrow, sometimes just a little, and starting on a higher scale with a small slit, helps. These seemingly minor innovations, when used together, contributed to a substantially lower complication rate sustained over a 22-year period - no leaks and only 20% stricture rate.
    Language English
    Publishing date 2022-11-14
    Publishing country India
    Document type Journal Article
    ZDB-ID 2164528-0
    ISSN 1998-3891 ; 0971-9261
    ISSN (online) 1998-3891
    ISSN 0971-9261
    DOI 10.4103/jiaps.jiaps_61_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article: Morphological Parameters of the Maghreb Bleak Tropidophoxinellus callensis (Leuciscidae) in an Algerian Mediterranean Stream

    Morsi, A. / Nouidjem, Y. / Mimeche, F.

    Journal of ichthyology. 2021 Nov., v. 61, no. 6

    2021  

    Abstract: Mediterranean streams and their specialised ichthyofauna are amongst the most threatened ecosystems and biota worldwide. The Maghreb bleak, Tropidophoxinellus callensis (Guichenot, 1850), is endemic to the Maghreb region and currently listed as Data ... ...

    Abstract Mediterranean streams and their specialised ichthyofauna are amongst the most threatened ecosystems and biota worldwide. The Maghreb bleak, Tropidophoxinellus callensis (Guichenot, 1850), is endemic to the Maghreb region and currently listed as Data Deficient in the IUCN Red List of Threatened Species. This study aims to provide the first detailed morphometry and growth parameters for this species. Our results reveal that there no significant (p > 0.05) difference between morphometric characters of male and female individuals. The linear regression analysisand the correlation coefficients suggested a significant relation (p < 0.01) between the length−length and length−weight relationship of the fish. This study provides novel and important data for fisheries and resource managers, and should be considered in terms of the species’ sustainability.
    Keywords Tropidophoxinellus ; females ; fish ; ichthyology ; males ; morphometry ; regression analysis ; streams ; threatened species ; Maghreb
    Language English
    Dates of publication 2021-11
    Size p. 818-824.
    Publishing place Pleiades Publishing
    Document type Article
    ZDB-ID 2227615-4
    ISSN 1555-6425 ; 0032-9452
    ISSN (online) 1555-6425
    ISSN 0032-9452
    DOI 10.1134/S0032945222010076
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  3. Article ; Online: Development and Validation of Green Chromatographic Approaches for Simultaneous Determination of Aspirin, Rosuvastatin and Clopidogrel in their Tertiary Mixture.

    Youssrey, Aya / Hegazy, Maha A / Morsi, Amani / Essam, Hebatallah M

    Journal of chromatographic science

    2022  Volume 61, Issue 10, Page(s) 930–942

    Abstract: Reduction of environmental pollution sources is the main target of green chemistry; it is applied across the life cycle of a chemical product. Scientists try to switch to eco-friendly practices to diminish the negative impact of chemicals and solvents on ...

    Abstract Reduction of environmental pollution sources is the main target of green chemistry; it is applied across the life cycle of a chemical product. Scientists try to switch to eco-friendly practices to diminish the negative impact of chemicals and solvents on the environment. Analytical chemistry is one of the main fields that mounted green chemistry approach. In this work, sensitive and selective green chromatographic methods with UV detection are described for the simultaneous determination of aspirin, rosuvastatin and clopidogrel. The first proposed method is an RP-HPLC one, which was described and successfully validated for the simultaneous separation and determination of the three components on Prontosil Hyperchom C18 (250 × 4.6 mm, 5 μm) column using an isocratic elution. The second method was a TLC spectrodensitometry in which the three components were separated, identified and quantified. The drugs were applied on silica gel plates, and developed using n-heptane: acetone: glacial acetic acid (60:40:0.4, by volume). The three drugs resolved bands were quantified by spectrodensitometric scanning at 240 nm. Both methods were validated according to ICH, statistically compared to the official methods with full greenness investigation to confirm that the proposed methods are viable alternatives for quality assessment of this combination.
    MeSH term(s) Chromatography, Thin Layer/methods ; Clopidogrel ; Rosuvastatin Calcium ; Aspirin ; Reproducibility of Results ; Chromatography, High Pressure Liquid/methods
    Chemical Substances Clopidogrel (A74586SNO7) ; Rosuvastatin Calcium (83MVU38M7Q) ; Aspirin (R16CO5Y76E)
    Language English
    Publishing date 2022-07-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80141-0
    ISSN 1945-239X ; 0021-9665
    ISSN (online) 1945-239X
    ISSN 0021-9665
    DOI 10.1093/chromsci/bmac058
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Reconstructing complex peripatellar defects using the descending genicular artery perforator flap.

    Hsieh, Yun-Huan / Kalmin, Doran / Motoroko, Maitumelo Imeldah / Morsi, Mohammed / Morsi, Adel

    ANZ journal of surgery

    2023  Volume 93, Issue 7-8, Page(s) 1950–1956

    Abstract: Background: Complex peripatellar defects are commonly reconstructed with free flaps or pedicled muscle flaps, whereas pedicled fasciocutaneous perforator flaps are commonly overlooked. The descending genicular artery perforator (DGAP) flap is a ... ...

    Abstract Background: Complex peripatellar defects are commonly reconstructed with free flaps or pedicled muscle flaps, whereas pedicled fasciocutaneous perforator flaps are commonly overlooked. The descending genicular artery perforator (DGAP) flap is a versatile flap that offers thin and pliable tissue that provides ideal 'like with like' peripatellar soft tissue defect reconstruction. This paper aims to demonstrate the safe use of a pedicled fasciocutaneous DGAP flap for extensive traumatic peripatellar defect reconstructions and to exhibit the surgical pearls via a case series.
    Methods: A retrospective cohort study of consecutive complex peripatellar reconstructions with DGAP flaps was conducted from January 2011 to December 2018. Patient demographics, medical comorbidities, aetiology/size/and location of the defects were reviewed. Flap, donor site, and overall surgical outcomes were clinically assessed and documented. Descriptive statistics were conducted and analysed by IBM SPSS Statistics 23.
    Results: Five consecutive cases with complex peripatellar defects (5 × 8 to 8 × 10 cm) were recruited. Two were males, and three were females, with a mean age of 38.4 years. Four were trauma, and one was an oncological case. Descending genicular artery (DGA) perforators and DGA terminal branches were consistent. One patient needed a split-thickness skin graft to reconstruct the secondary defects. All the flaps survived with an average follow-up of 24 months.
    Conclusion: The DGAP flap provides a reliable alternative to free flap for the large, complex peripatellar defect. With the inclusion of the proximal long saphenous vein and judicious selection of DGA perforators and its terminal branches, the DGAP flap can be harvested and used safely in the high-velocity impacted knee.
    MeSH term(s) Male ; Female ; Humans ; Adult ; Perforator Flap/blood supply ; Plastic Surgery Procedures ; Retrospective Studies ; Treatment Outcome ; Soft Tissue Injuries/surgery ; Arteries/surgery
    Chemical Substances N-(deoxyguanosin-8-yl)-2-aminopyrene (134249-04-0)
    Language English
    Publishing date 2023-06-19
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2050749-5
    ISSN 1445-2197 ; 1445-1433 ; 0004-8682
    ISSN (online) 1445-2197
    ISSN 1445-1433 ; 0004-8682
    DOI 10.1111/ans.18560
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article: Grape Seed Extract Alleviates Dexamethasone-Induced Hyperlipidemia, Lipid Peroxidation, and Hematological Alteration in Rats.

    Hasona, Nabil / Morsi, Abdullah

    Indian journal of clinical biochemistry : IJCB

    2018  Volume 34, Issue 2, Page(s) 213–218

    Abstract: The ameliorative effects of dietary natural compounds have drawn increasing attention. Dietary antioxidant is considered a common practice adopted in traditional and alternative medicine. The current study was considered to assess the ameliorative effect ...

    Abstract The ameliorative effects of dietary natural compounds have drawn increasing attention. Dietary antioxidant is considered a common practice adopted in traditional and alternative medicine. The current study was considered to assess the ameliorative effect of grape seed extract on dexamethasone-induced hepatotoxicity in rats. Rats were injected with dexamethasone, (0.1 mg/kg; i.m.), three times per week, for 30 days. The other groups; dexamethasone (0.1 mg/kg) and grape seed extract at a dose of 200 and 400 mg/kg were given orally to rats, respectively. Dexamethasone treatment resulted in a significant elevation in liver function markers activities, lipid profile, and hematological alterations; also, a remarkable increase in hepatic lipid peroxidation marker whereas decreased antioxidant activities in rats. However, administration of grape seed extract resulted in a reversal of dexamethasone-induced lipid peroxidation, antioxidant enzyme activities, liver function markers and lipid profile, and hematological alterations. Moreover, grape seed extract demonstrated preventive action against dexamethasone-induced histopathological changes in rat liver tissues. In conclusion, grape seed extract exhibited a protective effect in rats against oxidative stress, hyperlipidemia and hematological alterations induced by dexamethasone.
    Language English
    Publishing date 2018-02-07
    Publishing country India
    Document type Journal Article
    ZDB-ID 1033583-3
    ISSN 0974-0422 ; 0970-1915
    ISSN (online) 0974-0422
    ISSN 0970-1915
    DOI 10.1007/s12291-018-0736-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: The inverted love-heart flap: a new island flap design.

    Sreedharan, Sadhishaan / Zhou, Jieyun / Morsi, Adel

    Journal of plastic surgery and hand surgery

    2019  Volume 54, Issue 1, Page(s) 55–58

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Skin Neoplasms/surgery ; Surgical Flaps
    Language English
    Publishing date 2019-11-09
    Publishing country Sweden
    Document type Journal Article
    ZDB-ID 2551921-9
    ISSN 2000-6764 ; 2000-656X
    ISSN (online) 2000-6764
    ISSN 2000-656X
    DOI 10.1080/2000656X.2019.1688164
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Book ; Thesis: Solving MINLPs on loosely-coupled networks with applications in water and gas network optimization

    Morsi, Antonio

    Lösungsansätze für MINLPs auf schwach-gekoppelten Netzwerken mit Anwendungen in der Optimierung von Wasser- und Gasnetzen

    2013  

    Author's details von Antonio Morsi
    Language English ; German
    Size X, 186 S., graph. Darst., 210 mm x 148 mm, 303 g
    Publisher Verl. Dr. Hut
    Publishing place München
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., Diss.--Erlangen-Nürnberg, 2013
    Note Zsfassung in dt. Sprache
    ISBN 9783843911764 ; 3843911762
    Database Former special subject collection: coastal and deep sea fishing

    More links

    Kategorien

  8. Book ; Thesis: Solving MINLPs on loosely-coupled networks with applications in water and gas network optimization

    Morsi, Antonio

    Lösungsansätze für MINLPs auf schwach-gekoppelten Netzwerken mit Anwendungen in der Optimierung von Wasser- und Gasnetzen

    2013  

    Author's details von Antonio Morsi
    Language English ; German
    Size X, 186 S., graph. Darst., 210 mm x 148 mm, 303 g
    Publisher Verl. Dr. Hut
    Publishing place München
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., Diss.--Erlangen-Nürnberg, 2013
    Note Zsfassung in dt. Sprache
    ISBN 9783843911764 ; 3843911762
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

    More links

    Kategorien

  9. Book ; Online ; Thesis: Solving MINLPs on Loosely-Coupled Networks with Applications in Water and Gas Network Optimization

    Morsi, Antonio

    2013  

    Author's details Antonio Morsi
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Verlag Dr. Hut
    Publishing place München
    Document type Book ; Online ; Thesis
    ISBN 978-3-8439-1176-4 ; 3-8439-1176-2
    Database Digital theses on the web

    More links

    Kategorien

  10. Article ; Online: The potential gonadoprotective effects of grape seed extract against the histopathological alterations elicited in an animal model of cadmium-induced testicular toxicity.

    Morsi, A A / Shawky, L M / El Bana, E A

    Folia morphologica

    2020  Volume 79, Issue 4, Page(s) 767–776

    Abstract: Background: Grape seed extract (GSE) is a powerful antioxidant containing high levels of bioflavonoids, vitamin C and vitamin E. The aim of the work is to study the possible protective and ameliorative effects of grape seed extract in an animal model of ...

    Abstract Background: Grape seed extract (GSE) is a powerful antioxidant containing high levels of bioflavonoids, vitamin C and vitamin E. The aim of the work is to study the possible protective and ameliorative effects of grape seed extract in an animal model of cadmium (Cd)-induced testicular toxicity in rats.
    Materials and methods: A thirty-day oral gavage study in adult male albino rats was performed using 32 animals, randomly divided into four equal groups; negative control, Cd (5 mg/k/day), GSE (100 mg/k/day), and Cd + GSE. Testicular weights were measured. Haematoxylin and eosin (H&E) staining and proliferating nuclear cell antigen (PCNA) immunohistochemistry, as a marker for proliferation were done. Morphometric parameters were assessed and subjected to statistical analysis.
    Results: The H&E results showed atrophy and distortion of the seminiferous tubules (STs) with sloughing of the spermatogenic epithelium in cadmium group. The interstitial spaces were widened and showed oedema and mononuclear cell infiltrations. No remarkable changes were observed in the GSE-only group when compared to the control group. In Cd + GSE group, maintaining of the STs and their lining cells was evident. The immunohistochemical results showed marked positive PCNA immunoreactivity in both control and GSE groups, while negative immunoreaction was noticed in Cd group. Limited positive PCNA immunoreactivity was ameliorated in Cd + GSE group.
    Conclusions: Grape seed extract protected against cadmium-induced testicular toxicity in rats, reducing induced histopathological changes, and maintaining testicular histoarchitecture.
    MeSH term(s) Animals ; Antioxidants/pharmacology ; Cadmium/toxicity ; Disease Models, Animal ; Grape Seed Extract/pharmacology ; Male ; Rats ; Testis
    Chemical Substances Antioxidants ; Grape Seed Extract ; Cadmium (00BH33GNGH)
    Language English
    Publishing date 2020-01-13
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 419361-1
    ISSN 1644-3284 ; 0015-5659
    ISSN (online) 1644-3284
    ISSN 0015-5659
    DOI 10.5603/FM.a2020.0003
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top