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Book ; Online: On the open sea propagation of two-dimensional rotational water waves generated by a moving bed

Moscatelli, Frederick

2023

Abstract: We study the propagation of two-dimensional tsunami waves triggered by a seaquake in the open sea in the presence of underlying wind-generated currents, corresponding to background flows of constant vorticity. A suitable scaling of the governing ... ...

Abstract	We study the propagation of two-dimensional tsunami waves triggered by a seaquake in the open sea in the presence of underlying wind-generated currents, corresponding to background flows of constant vorticity. A suitable scaling of the governing equations introduces dimensionless parameters, of particular interest being the setting of linear waves that only depend on the vertical movement of the sea bed. We use Fourier analysis methods to extract formulae for the function $f$ which describes the vertical displacement of the water's free surface. We show that the results are particularly useful in the physically relevant shallow-water regime: in the irrotational case the predictions fit well with the observed behaviour of some historical tsunamis. In other situations, the stationary-phase principle gives insight into the asymptotic behaviour of $f$. Comment: This is an original manuscript of an article published by Taylor & Francis in Applicable Analysis on 09 Feb 2023, available at: http://www.tandfonline.com/10.1080/00036811.2023.2176306
Keywords	Mathematics - Analysis of PDEs ; 45G99 ; 58J32 ; 76B03
Subject code	551
Publishing date	2023-02-14
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: The Role of BIA Analysis in Osteoporosis Risk Development: Hierarchical Clustering Approach.

Sgarro, Giacinto Angelo / Grilli, Luca / Valenzano, Anna Antonia / Moscatelli, Fiorenzo / Monacis, Domenico / Toto, Giusi / De Maria, Antonella / Messina, Giovanni / Polito, Rita

Diagnostics (Basel, Switzerland)

2023 Volume 13, Issue 13

Abstract: Osteoporosis is a common musculoskeletal disorder among the elderly and a chronic condition which, like many other chronic conditions, requires long-term clinical management. It is caused by many factors, including lifestyle and obesity. Bioelectrical ... ...

Abstract	Osteoporosis is a common musculoskeletal disorder among the elderly and a chronic condition which, like many other chronic conditions, requires long-term clinical management. It is caused by many factors, including lifestyle and obesity. Bioelectrical impedance analysis (BIA) is a method to estimate body composition based on a weak electric current flow through the body. The measured voltage is used to calculate body bioelectrical impedance, divided into resistance and reactance, which can be used to estimate body parameters such as total body water (TBW), fat-free mass (FFM), fat mass (FM), and muscle mass (MM). This study aims to find the tendency of osteoporosis in obese subjects, presenting a method based on hierarchical clustering, which, using BIA parameters, can group patients who show homogeneous characteristics. Grouping similar patients into clusters can be helpful in the field of medicine to identify disorders, pathologies, or more generally, characteristics of significant importance. Another added value of the clustering process is the possibility to define cluster prototypes, i.e., imaginary patients who represent models of "states", which can be used together with clustering results to identify subjects with similar characteristics in a classification context. The results show that hierarchical clustering is a method that can be used to provide the detection of states and, consequently, supply a more personalized medicine approach. In addition, this method allowed us to elect BIA as a potential prognostic and diagnostic instrument in osteoporosis risk development.
Language	English
Publishing date	2023-07-06
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662336-5
ISSN	2075-4418
ISSN	2075-4418
DOI	10.3390/diagnostics13132292
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Article: Evaluation of Orexin-A Salivary Levels and its Correlation with Attention After Non-invasive Brain Stimulation in Female Volleyball Players.

Moscatelli, Fiorenzo / Monda, Antonietta / Messina, Antonietta / Monda, Marcellino / Monda, Vincenzo / Villano, Ines / De Maria, Antonella / Nicola, Mancini / Marsala, Gabriella / de Stefano, Maria Ida / Limone, Pierpaolo / Messina, Giovanni / Polito, Rita

Sports medicine - open

2024 Volume 10, Issue 1, Page(s) 32

Abstract: Background: The capacity to change attention from one area to another depending on the many environmental circumstances present is a crucial aspect of selective attention and is strictly correlated to reaction time. The cholinergic system of the basal ... ...

Abstract	Background: The capacity to change attention from one area to another depending on the many environmental circumstances present is a crucial aspect of selective attention and is strictly correlated to reaction time. The cholinergic system of the basal forebrain is crucial for attentive abilities. Several inputs, particularly orexin neurons, whose cell bodies are found in the postero-lateral hypothalamus, can activate the cholinergic system. The aim of this study was to investigate if high frequencies rTMS at dorsolateral prefrontal cortex (DLPFC) in highly trained volleyball players can change Orexin-A levels, attention and reaction time. This study was a double-blinded (participant and evaluator) matched-pair experimental design. Twenty right-handed female volleyball players were recruited for the study (age 24.6 ± 2.7 years; height 177.0 ± 5.5 cm; body mass 67.5 ± 6.5 kg; BMI 21.5 ± 1.2). Results: The main finding of this study was that 10 Hz rTMS to the DLPFC seems to increase Orexin-A salivary levels and the percentage of correct answers, while decreasing RT. After rTMS, the athletes show an increase in the percentage of correct answers immediately after the end of stimulation, and also after 15 and 30 min. Moreover, the athletes show decreases in reaction time after the end of stimulation and after 15 and 30 min to the end of stimulation, while no differences were found at the end of stimulation. Finally, the athletes show significant increases in Orexin-A salivary levels after stimulation with a peak after 30' of the end. Conclusion: The results of our study seem to indicate that there is a relationship between salivary Orexin-A levels and RT. These results could provide useful tools for modulating sports training; in fact, if confirmed, they could lead coaches to offer their athletes rTMS sessions appropriately integrated with training. In fact, alternating attention is a mental flexibility that enables people to change their point of focus and switch between tasks requiring various levels of cognition.
Language	English
Publishing date	2024-04-04
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2809942-4
ISSN	2198-9761 ; 2199-1170
ISSN (online)	2198-9761
ISSN	2199-1170
DOI	10.1186/s40798-024-00698-5
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Article ; Online: Exploring the Interplay between Bone Marrow Stem Cells and Obesity.

Moscatelli, Fiorenzo / Monda, Antonietta / Messina, Giovanni / Picciocchi, Elisabetta / Monda, Marcellino / Di Padova, Marilena / Monda, Vincenzo / Mezzogiorno, Antonio / Dipace, Anna / Limone, Pierpaolo / Messina, Antonietta / Polito, Rita

International journal of molecular sciences

2024 Volume 25, Issue 5

Abstract: Obesity, a complex disorder with rising global prevalence, is a chronic, inflammatory, and multifactorial disease and it is characterized by excessive adipose tissue accumulation and associated comorbidities. Adipose tissue (AT) is an extremely diverse ... ...

Abstract	Obesity, a complex disorder with rising global prevalence, is a chronic, inflammatory, and multifactorial disease and it is characterized by excessive adipose tissue accumulation and associated comorbidities. Adipose tissue (AT) is an extremely diverse organ. The composition, structure, and functionality of AT are significantly influenced by characteristics specific to everyone, in addition to the variability connected to various tissue types and its location-related heterogeneity. Recent investigation has shed light on the intricate relationship between bone marrow stem cells and obesity, revealing potential mechanisms that contribute to the development and consequences of this condition. Mesenchymal stem cells within the bone marrow, known for their multipotent differentiation capabilities, play a pivotal role in adipogenesis, the process of fat cell formation. In the context of obesity, alterations in the bone marrow microenvironment may influence the differentiation of mesenchymal stem cells towards adipocytes, impacting overall fat storage and metabolic balance. Moreover, bone marrow's role as a crucial component of the immune system adds another layer of complexity to the obesity-bone marrow interplay. This narrative review summarizes the current research findings on the connection between bone marrow stem cells and obesity, highlighting the multifaceted roles of bone marrow in adipogenesis and inflammation.
MeSH term(s)	Humans ; Adipose Tissue/metabolism ; Cell Differentiation ; Adipocytes/metabolism ; Adipogenesis ; Obesity/metabolism ; Inflammation/metabolism ; Bone Marrow Cells
Language	English
Publishing date	2024-02-27
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms25052715
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Article ; Online: Performance of 3D diamond detectors in small field dosimetry: The impact of pixel size.

Kanxheri, Keida / Talamonti, Cinzia / Sciortino, Silvio / Lagomarsino, Stefano / Ionica, Maria / Caprai, Mirco / Moscatelli, Francesco / Servoli, Leonello

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)

2022 Volume 102, Page(s) 73–78

Abstract: Purpose: Small photon beams used in radiotherapy techniques have inherent characteristics of charge particle disequilibrium and high-dose gradient making accurate dosimetry for such fields very challenging. By means of a 3D manufacturing technique, it ... ...

Abstract	Purpose: Small photon beams used in radiotherapy techniques have inherent characteristics of charge particle disequilibrium and high-dose gradient making accurate dosimetry for such fields very challenging. By means of a 3D manufacturing technique, it is possible to create arrays of pixels with a very small sensitive volume for radiotherapy dosimetry. We investigate the impact of 3D pixels size on absorbed dose sensitivity, linearity of response with dose rate, reproducibility and beam profile measurements. Methods: Diamond detectors with different pixel sizes have been produced in the 3DOSE experiment framework. To investigate the pixels size impact, they were tested using an Elekta Synergy LINAC. Dose rate dependence, absorbed dose sensitivity, reproducibility and beam profile measurement accuracy have been investigated and compared with PTW 60019 and IBA SFD reference dosimeters. Results: All of the 3D pixels had a linear and reproducible response to the dose rate. The sensitivity of a pixel decreases with its size, although even the smallest pixel has a high absorbed dose sensitivity (15 nC/Gy). The penumbra width measured with the smallest pixel size was consistent with the PTW microDiamond and differed by 0.2 mm from the IBA SFD diode. Conclusions: The study demonstrates that variation in pixel size do not affect the linearity of response with dose rate and the reproducibility of response. Due to the 3D geometry, the absorbed dose sensitivity of the detector remains high even for the smallest pixel, furthermore the pixel size was demonstrated to be of fundamental importance in the measurement of beam profiles.
MeSH term(s)	Diamond ; Particle Accelerators ; Photons/therapeutic use ; Radiation Dosimeters ; Radiometry/methods ; Reproducibility of Results
Chemical Substances	Diamond (7782-40-3)
Language	English
Publishing date	2022-09-18
Publishing country	Italy
Document type	Journal Article
ZDB-ID	1122650-x
ISSN	1724-191X ; 1120-1797
ISSN (online)	1724-191X
ISSN	1120-1797
DOI	10.1016/j.ejmp.2022.09.006
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Article ; Online: High frequencies (HF) repetitive transcranial magnetic stimulation (rTMS) increase motor coordination performances in volleyball players.

Moscatelli, Fiorenzo / Toto, Giusi Antonia / Valenzano, Anna / Cibelli, Giuseppe / Monda, Vincenzo / Limone, Pierpaolo / Mancini, Nicola / Messina, Antonietta / Marsala, Gabriella / Messina, Giovanni / Polito, Rita

BMC neuroscience

2023 Volume 24, Issue 1, Page(s) 30

Abstract: Introduction: It is widely demonstrated that high frequency (HF) repetitive transcranial magnetic stimulation (rTMS) has facilitative effects and is therefore capable to inducing changes in motor responses. One of the most investigated areas is the ... ...

Abstract	Introduction: It is widely demonstrated that high frequency (HF) repetitive transcranial magnetic stimulation (rTMS) has facilitative effects and is therefore capable to inducing changes in motor responses. One of the most investigated areas is the dorsolateral prefrontal cortex (DLPFC) as it plays a special executive attention role in actively preserving access to stimulus representations and objectives in environments with plenty of distraction such as those of team sports. Volleyball is a team sport in which the attention and coordination components are essential for achieving performance. Thus, the aim of this study was to investigate if HF rTMS at DLPFC in volleyball players can improve homolateral motor coordination and cortical excitability. Results: This study was a double-blinded (participant and evaluator) matched-pair experimental design. Twenty right-handed female volleyball players were recruited for the study and were randomly assigned either the active rTMS (n = 10) or the sham stimulation group (n = 10). The stimulation was performed in one session with 10 Hz, 80% of the resting motor threshold (RMT) of the right first dorsal interosseous muscle, 5 s of stimulation, and 15 s of rest, for a total of 1500 pulses. Before and after stimulation, the coordination and the cortical excitability were evaluated. The significant finding of this paper was that HF-rTMS of the DLPFC improved performance in terms of the homolateral interlimb coordination, with a significantly decreased in resting motor threshold and MEP latency of the ipsilateral motor cortex. It seem that HF-rTMS could increase coordination performances when the velocity of the execution is higher (120 bpm and 180 bpm). Conclusion: Moreover, in active rTMS group significant differences emerged after stimulation in RMT and in MEP latency, while no differences emerged after stimulation in MEP amplitude. In conclusion we believe that these results may be of great interest to the scientific community and may also have practical implications in the future.
MeSH term(s)	Humans ; Female ; Transcranial Magnetic Stimulation ; Volleyball ; Hand ; Motor Cortex ; Muscles
Language	English
Publishing date	2023-05-09
Publishing country	England
Document type	Journal Article
ZDB-ID	2041344-0
ISSN	1471-2202 ; 1471-2202
ISSN (online)	1471-2202
ISSN	1471-2202
DOI	10.1186/s12868-023-00796-2
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Article ; Online: Assessment of Lifestyle, Eating Habits and the Effect of Nutritional Education among Undergraduate Students in Southern Italy.

Moscatelli, Fiorenzo / De Maria, Antonella / Marinaccio, Luigi Antonio / Monda, Vincenzo / Messina, Antonietta / Monacis, Domenico / Toto, Giusi / Limone, Pierpaolo / Monda, Marcellino / Messina, Giovanni / Monda, Antonietta / Polito, Rita

Nutrients

2023 Volume 15, Issue 13

Abstract: Background: The years spent at university represent a critical period that can influence both the quality of lifestyle and the eating habits of subsequent adulthood, and also, in the long term, the health of the individual. The aim of this study was to ... ...

Abstract	Background: The years spent at university represent a critical period that can influence both the quality of lifestyle and the eating habits of subsequent adulthood, and also, in the long term, the health of the individual. The aim of this study was to investigate the lifestyle of university students living away from home. Methods: Each subject recruited for the study was given a questionnaire to obtain general information, eating habits and physical activity levels before (T0) and after six month of training seminars (T1). Blood pressure, body composition and questionnaire responses were investigated. Results: The main findings of this study are a significant decrement in blood pressure; an increment in physical activity practice; an increased number of subjects who pay attention to the calorific value of food and also an improvement in BIA parameters. Conclusions: In conclusion, this study demonstrated the challenges that university students face in leading a healthy lifestyle and caring for their nutritional needs, particularly when they are away from their families. No intervention specifically targets young adults, even though much emphasis is placed on the promotion of a healthy lifestyle based on a varied and balanced diet and sufficient exercise. Our study showed that it is possible to improve lifestyle through educational events aimed at making students aware of the health risks deriving from unhealthy lifestyles.
MeSH term(s)	Young Adult ; Humans ; Adult ; Life Style ; Health Education ; Students ; Educational Status ; Feeding Behavior ; Universities
Language	English
Publishing date	2023-06-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu15132894
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Article ; Online: Acute non invasive brain stimulation improves performances in volleyball players.

Moscatelli, Fiorenzo / Monda, Vincenzo / Limone, Pierpaolo / Marsala, Gabriella / Mancini, Nicola / Monda, Marcellino / Messina, Antonietta / De Maria, Antonella / Scarinci, Alessia / Monda, Antonietta / Polito, Rita / Messina, Giovanni

Physiology & behavior

2023 Volume 271, Page(s) 114356

Abstract: Objectives: The ability to redirect one's attention in response to various environmental situations is a crucial aspect of selective attention in team sports. Thus, the aim of this study was to investigate whether repetitive transcranial magnetic ... ...

Abstract	Objectives: The ability to redirect one's attention in response to various environmental situations is a crucial aspect of selective attention in team sports. Thus, the aim of this study was to investigate whether repetitive transcranial magnetic stimulation (rTMS) in volleyball players can improve Posner test response and cortical excitability. This study had a double-blinded (participant and evaluator) matched-pair experimental design. Methods: Twenty right-handed female volleyball players were recruited for the study and randomly assigned to either the active rTMS group (n = 10) or the sham stimulation group (n = 10). The stimulation was performed in one session with 10 Hz, 80% of the resting motor threshold (RMT), 5 s of stimulation, and 15 s of rest, for a total of 1,500 pulses. Before and after stimulation, the Posner test and cortical excitability were evaluated. Results: The significant finding of this paper was that 10 Hz rTMS to the DLPFC seemed to improve Posner test response, and also resulted in a significantly decreased RMT and MEP latency of the ipsilateral motor cortex. After stimulation, the active group showed a significant decrease in the percentage of errors in the Posner test. Moreover, active group showed faster RT after rTMS, suggesting that HF stimulation could enhance performance. Additionally, significant differences in RMT emerged in the active rTMS group after stimulation, while no differences were observed in MEP latency and MEP amplitude. Conclusion: In conclusion, we believe that these results may be of great interest to the scientific community and could have practical implications in the future.
MeSH term(s)	Humans ; Female ; Volleyball ; Transcranial Magnetic Stimulation/methods ; Brain ; Evoked Potentials, Motor
Language	English
Publishing date	2023-09-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	3907-x
ISSN	1873-507X ; 0031-9384
ISSN (online)	1873-507X
ISSN	0031-9384
DOI	10.1016/j.physbeh.2023.114356
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Article ; Online: The Ketogenic Diet and Neuroinflammation: The Action of Beta-Hydroxybutyrate in a Microglial Cell Line.

Polito, Rita / La Torre, Maria Ester / Moscatelli, Fiorenzo / Cibelli, Giuseppe / Valenzano, Anna / Panaro, Maria Antonietta / Monda, Marcellino / Messina, Antonietta / Monda, Vincenzo / Pisanelli, Daniela / Sessa, Francesco / Messina, Giovanni / Porro, Chiara

International journal of molecular sciences

2023 Volume 24, Issue 4

Abstract: The ketogenic diet (KD), a diet high in fat and protein but low in carbohydrates, is gaining much interest due to its positive effects, especially in neurodegenerative diseases. Beta-hydroxybutyrate (BHB), the major ketone body produced during the ... ...

Abstract	The ketogenic diet (KD), a diet high in fat and protein but low in carbohydrates, is gaining much interest due to its positive effects, especially in neurodegenerative diseases. Beta-hydroxybutyrate (BHB), the major ketone body produced during the carbohydrate deprivation that occurs in KD, is assumed to have neuroprotective effects, although the molecular mechanisms responsible for these effects are still unclear. Microglial cell activation plays a key role in the development of neurodegenerative diseases, resulting in the production of several proinflammatory secondary metabolites. The following study aimed to investigate the mechanisms by which BHB determines the activation processes of BV2 microglial cells, such as polarization, cell migration and expression of pro- and anti-inflammatory cytokines, in the absence or in the presence of lipopolysaccharide (LPS) as a proinflammatory stimulus. The results showed that BHB has a neuroprotective effect in BV2 cells, inducing both microglial polarization towards an M2 anti-inflammatory phenotype and reducing migratory capacity following LPS stimulation. Furthermore, BHB significantly reduced expression levels of the proinflammatory cytokine IL-17 and increased levels of the anti-inflammatory cytokine IL-10. From this study, it can be concluded that BHB, and consequently the KD, has a fundamental role in neuroprotection and prevention in neurodegenerative diseases, presenting new therapeutic targets.
MeSH term(s)	Humans ; 3-Hydroxybutyric Acid/pharmacology ; Microglia/metabolism ; Neuroinflammatory Diseases ; Diet, Ketogenic ; Lipopolysaccharides/pharmacology ; Anti-Inflammatory Agents/pharmacology ; Cytokines/metabolism ; Neuroprotective Agents/pharmacology
Chemical Substances	3-Hydroxybutyric Acid (TZP1275679) ; Lipopolysaccharides ; Anti-Inflammatory Agents ; Cytokines ; Neuroprotective Agents
Language	English
Publishing date	2023-02-04
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms24043102
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Article ; Online: Investigation of physical fitness profiles of undergraduate university students in Italy: a pilot study.

Moscatelli, Fiorenzo / Polito, Rita / LA Torre, Maria E / Vasco, Paride / Valenzano, Anna / Monda, Vincenzo / Cibelli, Giuseppe / DE Maria, Antonella / Scarinci, Alessia / Messina, Giovanni

The Journal of sports medicine and physical fitness

2023 Volume 63, Issue 12, Page(s) 1369–1370

MeSH term(s)	Humans ; Pilot Projects ; Universities ; Physical Fitness ; Students ; Italy
Language	English
Publishing date	2023-08-01
Publishing country	Italy
Document type	Journal Article
ZDB-ID	410823-1
ISSN	1827-1928 ; 0022-4707
ISSN (online)	1827-1928
ISSN	0022-4707
DOI	10.23736/S0022-4707.23.15392-8
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