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  1. Article ; Online: On predatory fungi feeding on free-living amoebae harbouring yeast-like endoparasites.

    Corsaro, Daniele / Müller, Karl-Dieter / Mosel, Frank / Jastrow, Holger / Walochnik, Julia / Michel, Rolf

    Parasitology research

    2023  Volume 122, Issue 10, Page(s) 2385–2392

    Abstract: Amoebae of the genus Vannella isolated from an ornamental fish aquarium were found to be infected with fungi. Upon plate culture, amoeba-trapping hyphal filaments were developed, and the amoeba trophozoites were found to harbour yeast-like parasites in ... ...

    Abstract Amoebae of the genus Vannella isolated from an ornamental fish aquarium were found to be infected with fungi. Upon plate culture, amoeba-trapping hyphal filaments were developed, and the amoeba trophozoites were found to harbour yeast-like parasites in their cytoplasm. Transfection of hyphae to a laboratory strain of Vannella resulted in the formation of conidia indicating the possible presence of zygomycetes of the genus Acaulopage, while efforts to culture the endoparasite remained unsuccessful. Biomolecular analysis based on rDNA revealed the presence of two distinct types of fungi, confirming the filamentous form as Acaulopage sp. (Zoopagomycota, Zoopagales) and identifying the yeast-like endoparasite as Cladosporium sp. (Ascomycota, Cladosporiales). To our knowledge, this is the first report of amoebae infected with Cladosporium.
    MeSH term(s) Animals ; Amoeba/microbiology ; Saccharomyces cerevisiae ; Fungi ; Spores, Fungal
    Language English
    Publishing date 2023-08-10
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 284966-5
    ISSN 1432-1955 ; 0932-0113 ; 0044-3255
    ISSN (online) 1432-1955
    ISSN 0932-0113 ; 0044-3255
    DOI 10.1007/s00436-023-07940-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Book ; Online: Verbundvorhaben: "Spitzencluster Solarvalley: FzSil Phase II - Optimierung des Float Zone-Verfahrens zur Herstellung von monokristallinen Siliziumkristallen für Solarzellen mit höherer Effizienz und geringeren Kosten"

    Becker, Frank / Mosel, Frank

    Teilvorhaben: "Konzeption, Bau und Test einer an den Solarmarkt angepassten Float Zone Kristallzuchtanlage" ; Verbundvorhaben im Teilbereich "Kristallisation & Wafering" des Spitzenclusters "Solar Valley Mitteldeutschland" im Spitzencluster-Wettbewerb des Bundesministeriums für Bildung und Forschung (BMBF) ; Abschlussbericht FzSil Phase II ; Laufzeit des Vorhabens und Berichtszeitraum: 01.06.2011 - 31.12.2013

    2014  

    Author's details Autoren: Frank Mosel; Frank Becker
    Language German
    Size Online-Ressource (26 S., 2,35 MB), Ill., graph. Darst.
    Publisher Technische Informationsbibliothek u. Universitätsbibliothek ; PVA TePla AG
    Publishing place Hannover ; Wettenberg
    Document type Book ; Online
    Note Förderkennzeichen BMBF 03SF0410A. - Verbund-Nr. 01094045 ; Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource können nicht ausgeschlossen werden
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  3. Article: Influence of the Single Nucleotide Polymorphisms rs12252 and rs34481144 in

    Čiučiulkaitė, Ieva / Siffert, Winfried / Elsner, Carina / Dittmer, Ulf / Wichert, Marc / Wagner, Bernd / Volbracht, Lothar / Mosel, Frank / Möhlendick, Birte

    Vaccines

    2023  Volume 11, Issue 7

    Abstract: The COVID-19 mRNA vaccine is the first mRNA vaccine approved for human administration by both the U.S. Food and Drug Administration and the European Medicines Agency. Studies have shown that the immune response and the decay of immunity after vaccination ...

    Abstract The COVID-19 mRNA vaccine is the first mRNA vaccine approved for human administration by both the U.S. Food and Drug Administration and the European Medicines Agency. Studies have shown that the immune response and the decay of immunity after vaccination with the COVID-19 vaccines are variable within a population. Host genetic factors probably contribute to this variability. In this study, we investigated the effect of the single-nucleotide polymorphisms rs12252 and rs34481144 in the
    Language English
    Publishing date 2023-07-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines11071257
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Principal component analysis of MALDI TOF MS mass spectra separates M. abscessus (sensu stricto) from M. massiliense isolates.

    Kehrmann, Jan / Wessel, Sarah / Murali, Roshni / Hampel, Annegret / Bange, Franz-Christoph / Buer, Jan / Mosel, Frank

    BMC microbiology

    2016  Volume 16, Page(s) 24

    Abstract: Background: The discrimination of the members of the Mycobacterium abscessus complex is of clinical interest because one of the subspecies, M. massiliense, exhibits higher rates of response to antibiotic treatment for lung infection than do the other ... ...

    Abstract Background: The discrimination of the members of the Mycobacterium abscessus complex is of clinical interest because one of the subspecies, M. massiliense, exhibits higher rates of response to antibiotic treatment for lung infection than do the other members of that complex. M. abscessus complex contains three subspecies that are laborious to identify; therefore, a routine diagnostic tool would be worthwhile.
    Results: We used principal component analysis, hierarchical cluster analysis, and single-peak analysis to examine peak lists derived from matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI TOF MS) mass spectra of 50 clinical M. abscessus complex isolates, including 28 M. abscessus (sensu stricto), 19 M. massiliense, and 3 M. bolletii isolates grown in mycobacterium growth indicator tube liquid medium and prepared with a bead-based protocol. Principal component analysis but not hierarchical cluster analysis separated M. abscessus (sensu stricto) isolates and M. massiliense isolates into two clusters. Furthermore, single-peak analysis displayed 4 discriminating peaks that separated M. abscessus (sensu stricto) from M. massiliense isolates. M. bolletii isolates did not exhibit specific peaks but resembled the M. abscessus (sensu stricto) peak profile and also grouped within this principal component analysis cluster. Principal component analysis of all peak lists with the exclusion of the four discriminating peaks again separated M. abscessus (sensu stricto) from M. massiliense isolates, thus relativizing the importance of these peaks for subspecies identification.
    Conclusions: Principal component analysis of peak lists derived from MALDI TOF mass spectra is a robust and convenient method of discriminating M. massiliense isolates from the other members of the M. abscessus complex.
    MeSH term(s) Bacterial Typing Techniques/methods ; Humans ; Mycobacterium/chemistry ; Mycobacterium/classification ; Mycobacterium/isolation & purification ; Mycobacterium Infections/microbiology ; Phylogeny ; Principal Component Analysis ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods
    Language English
    Publishing date 2016-03-01
    Publishing country England
    Document type Evaluation Studies ; Journal Article
    ISSN 1471-2180
    ISSN (online) 1471-2180
    DOI 10.1186/s12866-016-0636-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Performance of Vitek MS in identifying nontuberculous mycobacteria from MGIT liquid medium and Lowenstein-Jensen solid medium.

    Kehrmann, Jan / Schoerding, Ann-Kathrin / Murali, Roshni / Wessel, Sarah / Koehling, Hedda Luise / Mosel, Frank / Buer, Jan

    Diagnostic microbiology and infectious disease

    2016  Volume 84, Issue 1, Page(s) 43–47

    Abstract: Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry is a fast and inexpensive method for bacterial identification. The aim of this study was to analyze the performance of Vitek MS in identifying 160 nontuberculous mycobacterial ... ...

    Abstract Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry is a fast and inexpensive method for bacterial identification. The aim of this study was to analyze the performance of Vitek MS in identifying 160 nontuberculous mycobacterial isolates of 24 species from Lowenstein-Jensen solid medium and BACTEC MGIT 960 liquid medium using a bead-based method. The system correctly identified 76.9% of the isolates (123 of 160) cultivated on solid medium and 76.9% (123 of 160) of positive liquid cultures. None of the isolates included in the study was misidentified. Although the overall performance of Vitek MS with the SARAMIS 4.12 database was comparable in identifying mycobacterial species grown on solid medium and in liquid medium, the identification rate varied notably between the various species analyzed, which currently limits the utility for identification in routine diagnostics for some species.
    MeSH term(s) Bacteriological Techniques/methods ; Culture Media/chemistry ; Humans ; Mycobacterium Infections, Nontuberculous/diagnosis ; Nontuberculous Mycobacteria/chemistry ; Nontuberculous Mycobacteria/classification ; Nontuberculous Mycobacteria/isolation & purification ; Sensitivity and Specificity ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods
    Chemical Substances Culture Media
    Language English
    Publishing date 2016-01
    Publishing country United States
    Document type Evaluation Studies ; Journal Article
    ZDB-ID 604920-5
    ISSN 1879-0070 ; 0732-8893
    ISSN (online) 1879-0070
    ISSN 0732-8893
    DOI 10.1016/j.diagmicrobio.2015.10.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1845: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  6. Book ; Thesis: Ein internes Wasserstofftarget für Speicherringexperimente

    Mosel, Frank

    1994  

    Author's details von Frank Mosel
    Language German
    Size 59 S, graph. Darst
    Edition [Mikrofiche-Ausg.]
    Document type Book ; Thesis
    Thesis / German Habilitation thesis @Bonn, Univ., Diss. : 1994
    Note Mikrofiche-Ausg.: 1994. 1 Mikrofiche : 24x
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  7. Book ; Thesis: Ein internes Wasserstofftarget für Speicherringexperimente

    Mosel, Frank

    1994  

    Author's details von Frank Mosel
    Language German
    Size 59 S, graph. Darst
    Edition [Mikrofiche-Ausg.]
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., Diss.--Bonn, 1994
    Note Mikrofiche-Ausg.: 1994. 1 Mikrofiche : 24x
    Database Former special subject collection: coastal and deep sea fishing

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  8. Book ; Thesis: Kristallzüchtung von semiisolierenden Fe-dotierten InP-Kristallen mit dem Czochralski-Verfahren (LEC)

    Mosel, Frank

    1993  

    Author's details von Frank Mosel
    Language Undetermined
    Size 138 S, Ill., graph. Darst
    Document type Book ; Thesis
    Thesis / German Habilitation thesis @Erlangen, Nürnberg, Univ., Diss. : 1993
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  9. Article ; Online: Delineation of Stenotrophomonas maltophilia isolates from cystic fibrosis patients by fatty acid methyl ester profiles and matrix-assisted laser desorption/ionization time-of-flight mass spectra using hierarchical cluster analysis and principal component analysis.

    Vidigal, Pedrina Gonçalves / Mosel, Frank / Koehling, Hedda Luise / Mueller, Karl Dieter / Buer, Jan / Rath, Peter Michael / Steinmann, Joerg

    Journal of medical microbiology

    2014  Volume 63, Issue Pt 12, Page(s) 1615–1620

    Abstract: Stenotrophomonas maltophilia is an opportunist multidrug-resistant pathogen that causes a wide range of nosocomial infections. Various cystic fibrosis (CF) centres have reported an increasing prevalence of S. maltophilia colonization/infection among ... ...

    Abstract Stenotrophomonas maltophilia is an opportunist multidrug-resistant pathogen that causes a wide range of nosocomial infections. Various cystic fibrosis (CF) centres have reported an increasing prevalence of S. maltophilia colonization/infection among patients with this disease. The purpose of this study was to assess specific fingerprints of S. maltophilia isolates from CF patients (n = 71) by investigating fatty acid methyl esters (FAMEs) through gas chromatography (GC) and highly abundant proteins by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), and to compare them with isolates obtained from intensive care unit (ICU) patients (n = 20) and the environment (n = 11). Principal component analysis (PCA) of GC-FAME patterns did not reveal a clustering corresponding to distinct CF, ICU or environmental types. Based on the peak area index, it was observed that S. maltophilia isolates from CF patients produced significantly higher amounts of fatty acids in comparison with ICU patients and the environmental isolates. Hierarchical cluster analysis (HCA) based on the MALDI-TOF MS peak profiles of S. maltophilia revealed the presence of five large clusters, suggesting a high phenotypic diversity. Although HCA of MALDI-TOF mass spectra did not result in distinct clusters predominantly composed of CF isolates, PCA revealed the presence of a distinct cluster composed of S. maltophilia isolates from CF patients. Our data suggest that S. maltophilia colonizing CF patients tend to modify not only their fatty acid patterns but also their protein patterns as a response to adaptation in the unfavourable environment of the CF lung.
    MeSH term(s) Adolescent ; Adult ; Bacterial Proteins/analysis ; Bacteriological Techniques/methods ; Child ; Chromatography, Gas/methods ; Cluster Analysis ; Cystic Fibrosis/complications ; Environmental Microbiology ; Fatty Acids/analysis ; Female ; Gram-Negative Bacterial Infections/diagnosis ; Gram-Negative Bacterial Infections/microbiology ; Humans ; Intensive Care Units ; Male ; Middle Aged ; Principal Component Analysis ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods ; Stenotrophomonas maltophilia/chemistry ; Stenotrophomonas maltophilia/isolation & purification ; Time Factors ; Young Adult
    Chemical Substances Bacterial Proteins ; Fatty Acids
    Language English
    Publishing date 2014-09-29
    Publishing country England
    Document type Evaluation Study ; Journal Article
    ZDB-ID 218356-0
    ISSN 1473-5644 ; 0022-2615
    ISSN (online) 1473-5644
    ISSN 0022-2615
    DOI 10.1099/jmm.0.076950-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 634: Show issues Location:
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  10. Article: Monitoring of endoscope reprocessing with an adenosine triphosphate (ATP) bioluminescence method.

    Parohl, Nina / Stiefenhöfer, Doris / Heiligtag, Sabine / Reuter, Henning / Dopadlik, Dana / Mosel, Frank / Gerken, Guido / Dechêne, Alexander / Heintschel von Heinegg, Evelyn / Jochum, Christoph / Buer, Jan / Popp, Walter

    GMS hygiene and infection control

    2017  Volume 12, Page(s) Doc04

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2017-03-27
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2717852-3
    ISSN 2196-5226
    ISSN 2196-5226
    DOI 10.3205/dgkh000289
    Database MEDical Literature Analysis and Retrieval System OnLINE

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