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  1. Article ; Online: Response to: cytokine profile of autologous conditioned serum for treatment of osteoarthritis, in vitro effects on cartilage metabolism and intra-articular levels after injection.

    Moser, Carsten

    Arthritis research & therapy

    2010  Volume 12, Issue 6, Page(s) 410; author reply 411

    MeSH term(s) Antirheumatic Agents/pharmacology ; Cartilage, Articular/metabolism ; Culture Media, Conditioned/chemistry ; Culture Media, Conditioned/pharmacology ; Cytokines/metabolism ; Humans ; Osteoarthritis, Knee/drug therapy ; Osteoarthritis, Knee/metabolism ; Research Design ; Synovial Fluid/chemistry
    Chemical Substances Antirheumatic Agents ; Culture Media, Conditioned ; Cytokines
    Language English
    Publishing date 2010-12-17
    Publishing country England
    Document type Comment ; Letter
    ZDB-ID 2107602-9
    ISSN 1478-6362 ; 1478-6354
    ISSN (online) 1478-6362
    ISSN 1478-6354
    DOI 10.1186/ar3146
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: How does surgery compare with advanced intra-articular therapies in knee osteoarthritis: current thoughts.

    Wehling, Peter / Moser, Carsten / Maixner, William

    Therapeutic advances in musculoskeletal disease

    2016  Volume 8, Issue 3, Page(s) 72–85

    Abstract: The objectives of osteoarthritis (OA) management are to reduce pain and inflammation, slow cartilage degradation, improve function and reduce disability. Current strategies for managing knee OA include nonpharmacological interventions, oral ... ...

    Abstract The objectives of osteoarthritis (OA) management are to reduce pain and inflammation, slow cartilage degradation, improve function and reduce disability. Current strategies for managing knee OA include nonpharmacological interventions, oral pharmacological treatments, localized intra-articular injections, and surgery. It has become evident that the inflammatory response is a key contributor to the development and progression of knee OA. Signaling pathways involving growth factors and cytokines are being investigated for the development of new therapies that target the underlying biological processes causing the disease. This concept of 'molecular orthopedics' enables more patient-centered diagnostic and treatment strategies. In contrast to other conservative therapies, which ultimately only address OA symptoms, intra-articular injections, in particular autologous conditioned serum (ACS), provide benefits that have the potential to outweigh those of established pharmacological treatments and surgery. Surgery has historically been considered the final solution for treatment of knee OA, both by treating physicians and by patients; however, there are increasing concerns regarding the lack of randomized clinical trials providing evidence to support this opinion. Intra-articular injection of ACS has demonstrated efficacy as a treatment for knee OA in a number of studies, with a very low rate of adverse events and side effects, compared with surgery. Treatment with ACS utilizes the release of anti-inflammatory cytokines and regenerative growth factors to support the natural healing processes in the knee, and has the potential to provide a valuable alternative to surgical intervention.
    Language English
    Publishing date 2016-04-18
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2516075-8
    ISSN 1759-7218 ; 1759-720X
    ISSN (online) 1759-7218
    ISSN 1759-720X
    DOI 10.1177/1759720X16642405
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Tomographische periradikuläre Mikrotherapie

    Grönemeyer, Dietrich / Thiel, Hans-Joachim / Moser, Carsten

    2013  

    Author's details Dietrich Grönemeyer ; Hans-Joachim Thiel ; Carsten Moser
    Keywords Bandscheibenkrankheit ; Schmerztherapie ; Interventionsradiologie ; Minimal-invasive Chirurgie
    Subject MIC ; Minimal invasive surgery ; Mikro-invasive Chirurgie ; Endoskopische Chirurgie ; Operative Endoskopie ; Chirurgische Endoskopie ; Therapeutische Endoskopie ; Video-assistierte Telechirurgie ; Schlüssellochchirurgie ; Knopflochchirurgie ; Less invasive surgery ; Interventionelle Radiologie ; Interventionelle minimal-invasive Radiologie ; Schmerz ; Bandscheibenleiden
    Subject code 617.5640597
    Language German
    Size V, 186 S., Ill., 25 cm
    Publisher ABW, Wiss.-Verl
    Publishing place Berlin
    Publishing country Germany
    Document type Book
    Note Literaturangaben
    HBZ-ID HT018285964
    ISBN 978-3-940615-39-8 ; 3-940615-39-0
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: Correction to: Intraarticular application of autologous conditioned serum (ACS) reduces bone tunnel widening after ACL reconstructive surgery in a randomized controlled trial.

    Darabos, Nikica / Haspl, Miroslav / Moser, Carsten / Darabos, Anela / Bartolek, Dubravka / Groenemeyer, Dietrich

    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA

    2018  Volume 27, Issue 4, Page(s) 1355

    Abstract: The Orthokine product used in the trial was donated by the manufacturer. ...

    Abstract The Orthokine product used in the trial was donated by the manufacturer.
    Language English
    Publishing date 2018-10-12
    Publishing country Germany
    Document type Published Erratum
    ZDB-ID 1159064-6
    ISSN 1433-7347 ; 0942-2056
    ISSN (online) 1433-7347
    ISSN 0942-2056
    DOI 10.1007/s00167-018-5222-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Conference proceedings: Biotechnologische Konzepte zur konservativen Behandlung von Rückenschmerzen – Alternativen zu Glukokortikoiden

    Moser, Carsten / Grönemeyer, Dietrich

    2014  , Page(s) WI54–384

    Event/congress Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2014); Berlin; ; Berufsverband der Fachärzte für Orthopädie; 2014
    Keywords Medizin, Gesundheit
    Publishing date 2014-10-13
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/14dkou381
    Database German Medical Science

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  6. Book ; Thesis: Die Desorption von Ammoniak aus Wassertropfen im Ultraschall-Stehwellenfeld

    Möser, Carsten

    Experiment und Modellbildung

    (Berichte aus der Verfahrenstechnik)

    2001  

    Author's details Carsten Möser
    Series title Berichte aus der Verfahrenstechnik
    Keywords Binäres Gemisch ; Schweben ; Stehende Welle ; Desorption ; Tropfen ; Wasser ; Ultraschall ; Ammoniak
    Language German
    Size 169 S, Ill, 21 cm
    Publisher Shaker
    Publishing place Aachen
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., Fak. für Verfahrens- und Systemtechnik, Diss.--Magdeburg, 2001
    ISBN 3826587405 ; 9783826587405
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  7. Book ; Online ; Thesis: Wirksamkeit und Sicherheit intraartikulärer Osteoarthritis-Behandlung mit autologem, konditioniertem Serum (Autologous Conditioned Serum - ACS) Akronym: German Orthokine OsteoArthritis Trial - GOAT

    Moser, Carsten [Verfasser] / Baltzer, Axel [Akademischer Betreuer] / Lögters, Tim [Akademischer Betreuer]

    2016  

    Author's details Carsten Moser. Gutachter: Axel Baltzer ; Tim Lögters
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf
    Publishing place Düsseldorf
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  8. Book ; Thesis: Detektion tumor-assoziierter Punktmutationen im Kras-Protoonkogen in Stuhlproben von Patienten mit sporadischen kolorektalen Neoplasien

    Moser, Carsten

    Int. J. Cancer 1996. 66 u.d.T.:Peter Nollau, Carsten Moser [u.a.]: Detection of K-ras mutations in stools of patients with colorectal cancer by mutant-enriched PCR

    1997  

    Title variant Detection of K-ras mutations in stools of patients with colorectal cancer by mutant-enriched PCR
    Author's details vorgelegt von Carsten Moser
    Language English
    Size S.332 - 336, Ill
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., FB Medizin, Diss.--Hamburg, 1998
    Note Text in engl. Sprache
    Database Former special subject collection: coastal and deep sea fishing

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  9. Article ; Online: A novel Laser Navigation System reduces radiation exposure and improves accuracy and workflow of CT-guided spinal interventions: a prospective, randomized, controlled, clinical trial in comparison to conventional freehand puncture.

    Moser, Carsten / Becker, Jan / Deli, Martin / Busch, Martin / Boehme, Marc / Groenemeyer, Dietrich H W

    European journal of radiology

    2013  Volume 82, Issue 4, Page(s) 627–632

    Abstract: Purpose: Phantom model evaluation and prospective randomized clinical trial to assess the clinical feasibility and benefit of using a novel Laser Navigation System (LNS) in CT-guided epidural and perineural injections in comparison to the conventional ... ...

    Abstract Purpose: Phantom model evaluation and prospective randomized clinical trial to assess the clinical feasibility and benefit of using a novel Laser Navigation System (LNS) in CT-guided epidural and perineural injections in comparison to the conventional freehand procedure.
    Methods: The LNS guided puncture technique was compared to the standard CT-guided freehand treatment using a phantom model and a randomized clinical trial. Spinal injections were administered by an experienced interventional team to evaluate needle placement accuracy, treatment time and radiation exposure.
    Results: In the LNS group of the phantom model study, the needle entrance point accuracy of 0.5mm (freehand 3.1mm), needle target point accuracy of 2.0mm (freehand 3.5mm), number of control CT slices of 1.4 (freehand 2.7) and needle placement time of 5min 4s (freehand: 9min 18s) showed significant improvements compared to freehand in 60 punctures. In the clinical trial the LNS group achieved needle entrance point accuracy of 1.3mm (freehand 4.6mm), needle angulation accuracy of 0.4° (freehand 2.3°), number of control CT slices of 1.1 (freehand 1.8) and needle placement time of 6min 54s (freehand 9min 00s), showing significant improvements compared to freehand in a total of 58 CT-guided interventions.
    Conclusion: The LNS group showed significantly improved results in both study designs. Both the phantom model evaluation and the clinical trial of spinal injections showed feasibility and efficacy of using the novel LNS. Even an experienced interventional team worked with it more precise, faster and with reduced radiation exposure.
    MeSH term(s) Adult ; Aged ; Feasibility Studies ; Female ; Humans ; Injections, Spinal ; Lasers ; Low Back Pain/drug therapy ; Male ; Middle Aged ; Needles ; Phantoms, Imaging ; Prospective Studies ; Punctures ; Radiation Dosage ; Radiography, Interventional/instrumentation ; Statistics, Nonparametric ; Steroids/administration & dosage ; Steroids/therapeutic use ; Surgery, Computer-Assisted/instrumentation ; Tomography, X-Ray Computed/instrumentation
    Chemical Substances Steroids
    Language English
    Publishing date 2013-04
    Publishing country Ireland
    Document type Comparative Study ; Journal Article ; Randomized Controlled Trial
    ZDB-ID 138815-0
    ISSN 1872-7727 ; 0720-048X
    ISSN (online) 1872-7727
    ISSN 0720-048X
    DOI 10.1016/j.ejrad.2012.10.028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Conference proceedings: Arthroskopische Behandlung isolierter, vollschichtiger Knorpelschäden bei CAM- Impingement des Hüftgelenkes durch autologe Chondrozytentransplantation (ACT3D) – Klinische und radiologische Verlaufsbeobachtung über 2 Jahre

    Körsmeier, Konrad / Kaminga, Michael / Moser, Carsten / Sobik, Hanna Maria

    2013  , Page(s) WI37–722

    Event/congress Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2013); Berlin; ; Berufsverband der Fachärzte für Orthopädie; 2013
    Keywords Medizin, Gesundheit ; Hüftarthroskopie ; Knorpelzelltransplantation ; Sphäroide ; CAM-Impingement ; Arthrose Hüftgelenk
    Publishing date 2013-10-23
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/13dkou255
    Database German Medical Science

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