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  1. AU="Mostafa Ahmed Khairy"
  2. AU=Wilkes M S
  3. AU="Zhong, Baichang"
  4. AU="Kirsch, Harald"
  5. AU=Gibson Spencer J

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  1. Artikel ; Online: Imaging of asbestos-related lung and pleural diseases as an endemic exposure in Egypt

    Marian Fayek Kolta / Mostafa Ahmed Khairy / Yasmine Hamdy El Hinnawy

    The Egyptian Journal of Radiology and Nuclear Medicine, Vol 51, Iss 1, Pp 1-

    2020  Band 7

    Abstract: Abstract Background Asbestos refers to a group of naturally occurring silicate minerals which have been traditionally used in building materials and household products. Inhalation of asbestos fibers, however, has been associated with adverse health ... ...

    Abstract Abstract Background Asbestos refers to a group of naturally occurring silicate minerals which have been traditionally used in building materials and household products. Inhalation of asbestos fibers, however, has been associated with adverse health outcomes, with the disease manifestations principally affecting the thorax. The aim of our study is to detect and evaluate the different radiological patterns of asbestos-related lung and pleural disease and its complications Results MDCT examination was able to assess and distinguish asbestosis as well as asbestos-related lung and pleural disease besides detection of any associated complications. Conclusion This study demonstrates that while reporting of malignant asbestos-related pleural disease is adequate, there is room for improvement in the reporting of more benign disease.
    Schlagwörter Asbestos ; Mesothelioma ; Bronchogenic carcinoma ; Round atelectasis ; Pleural plaques ; MSCT ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2020-03-01T00:00:00Z
    Verlag SpringerOpen
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Artikel ; Online: Role of diffusion MRI in diagnosis of mediastinal lymphoma

    Youssriah Yahia Sabri / Nourhan Mohamed Ewis / Hussam Eldin Hamdy Zawam / Mostafa Ahmed Khairy

    The Egyptian Journal of Radiology and Nuclear Medicine, Vol 52, Iss 1, Pp 1-

    initial assessment and response to therapy

    2021  Band 11

    Abstract: Abstract Background Malignant lymphoma accounts for nearly 20% of all mediastinal neoplasms in adults and 50% in children. Hodgkin’s disease is the most common primary mediastinal lymphoma. In non-Hodgkin’s lymphoma, the two most common forms of primary ... ...

    Abstract Abstract Background Malignant lymphoma accounts for nearly 20% of all mediastinal neoplasms in adults and 50% in children. Hodgkin’s disease is the most common primary mediastinal lymphoma. In non-Hodgkin’s lymphoma, the two most common forms of primary mediastinal lymphoma are lymphoblastic lymphoma and diffuse large B-cell lymphoma. The aim of this study is to implement diffusion MRI in the algorithm of diagnosis of mediastinal lymphoma, differentiating Hodgkin's from non-Hodgkin's lymphoma and assessment of post therapeutic response. Results Using Diffusion weighted magnetic resonance imaging DWI-MRI, there were statistic significant difference between ADC values in lymph nodes and mediastinal masses in Hodgkin and non-Hodgkin lymphomas. ADC range in non-treated Hodgkin lymphoma cases was 0.774 to 1.4, while ADC range in in non-treated non-Hodgkin lymphoma was 0.476 to 0.668. In this study, there was statistically significant difference of ADC values in lymphoma cases presented by mediastinal masses with and without chemotherapy. Conclusions Diffusion weighted magnetic resonance imaging DWI-MRI is a promising functional technique in diagnosis of Hodgkin's and non-Hodgkin's lymphoma and assessment of response to treatment with no need for special preparation, contrast injection or radiation exposure.
    Schlagwörter Mediastinum ; Malignant ; Lymphoma ; Hodgkin ; Non-Hodgkin ; Diffusion ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2021-08-01T00:00:00Z
    Verlag SpringerOpen
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  3. Artikel ; Online: Computed tomographic features of pulmonary pure ground-glass nodule

    Mona Ahmed Fouad Hafez / Arwa Mohammed Abdulbaset Emam Elgaml / Mostafa Ahmed Khairy / Yasmine Hamdy El Hinnawy / Mohammed Raafat Abd-Elmageed

    The Egyptian Journal of Radiology and Nuclear Medicine, Vol 53, Iss 1, Pp 1-

    a comparison between neoplastic and non-neoplastic nodules

    2022  Band 10

    Abstract: Abstract Background Ground-glass nodules (GGNs) are detected more frequently nowadays with the increase in MDCT resolution and applications. On CT GGN is a well circumscribed nodule with mild increase attenuation and not obscuring bronchial and vascular ... ...

    Abstract Abstract Background Ground-glass nodules (GGNs) are detected more frequently nowadays with the increase in MDCT resolution and applications. On CT GGN is a well circumscribed nodule with mild increase attenuation and not obscuring bronchial and vascular markings. This study aimed to discriminate neoplastic from non-neoplastic pure ground-glass nodules (pGGNs) by performing comparative quantitative and qualitative assessment of main features in computed tomography (CT) chest imaging. This prospective study involved 72 patients, who were referred to perform multidetector computed tomography of the chest in the radiology department. Cases with ground-glass pulmonary nodules were included in the study, and each nodule was assessed and followed for 2 years by a radiomics software for density and histogram analysis and then classified to neoplastic and non-neoplastic nodules. Neoplastic and non-neoplastic nodules morphology and radiomics were compared, and statistical analysis was done. Results After histopathology, positron emission tomography and computed tomography, or close follow-up, pGGNs were classified to neoplastic and non-neoplastic nodules. There was statistically significant difference regarding the mean size, where in cases of neoplastic nodules it was 6.66 mm and the mean size of benign nodules was 11.25 mm. Moreover, irregularity index and histogram peak frequency had a significant correlation with a P value of 0.007 and 0.022, respectively. The cutoff level for peak frequency percentage was 20.5% with 56.3% sensitivity and 79.2% specificity. Conclusions Radiomics had a growing role in pulmonary nodule assessment. Radiomics along with morphologic features assessment improved the detection efficiency of neoplastic versus non-neoplastic ground-glass nodules with histogram peak frequency, nodule size, and irregularity index as the main differentiating factors in this study.
    Schlagwörter Ground glass ; Pulmonary nodules ; CT chest ; Histogram ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Sprache Englisch
    Erscheinungsdatum 2022-11-01T00:00:00Z
    Verlag SpringerOpen
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel ; Online: Systemic sclerosis

    Iman Mohamed Hamdy Ibrahim / Sherif Mohamed Gamal / Adham Mamdouh Salama / Mostafa Ahmed Khairy

    The Egyptian Journal of Radiology and Nuclear Medicine, Vol 51, Iss 1, Pp 1-

    correlation between lung abnormalities on high-resolution computed tomography (HRCT) and pulmonary function tests (PFTs)

    2020  Band 13

    Abstract: Abstract Background Systemic sclerosis is a connective tissue disease that affects multiple systems and causes fibrosis of the skin and internal organs. There are two ways in which the lungs can be involved in patients with systemic sclerosis, either ... ...

    Abstract Abstract Background Systemic sclerosis is a connective tissue disease that affects multiple systems and causes fibrosis of the skin and internal organs. There are two ways in which the lungs can be involved in patients with systemic sclerosis, either isolated pulmonary hypertension or interstitial lung fibrosis. The purpose of this study is to correlate the high resolution CT findings with pulmonary function tests in patients with systemic sclerosis to evaluate the severity of lung changes. Results Significant inverse correlations were found between the maximal extent radiological score, maximal severity radiological score as well as total (global) radiological score on one hand and the pulmonary function tests on the other hand Conclusion The combination of high resolution CT and pulmonary function tests are recommended for better assessment of the extent and severity of systemic sclerosis associated interstitial lung disease.
    Schlagwörter Systemic sclerosis ; High-resolution CT ; Pulmonary function tests ; Interstitial lung disease ; Pulmonary hypertension ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2020-06-01T00:00:00Z
    Verlag SpringerOpen
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  5. Artikel ; Online: Mediastinal lymphadenopathy in sarcoidosis

    Youssriah Yahia Sabri / Naglaa Mahmoud Mohamed Mahmoud / Mohammed Raafat Abd El–Mageed / Marwa Mohammed Mohammed Onsy / Sabah Ahmed Mohamed / Mahmoud Mohamed Mohamed Onsy / Mostafa Ahmed Khairy

    The Egyptian Journal of Radiology and Nuclear Medicine, Vol 54, Iss 1, Pp 1-

    Can diffusion MRI play a role in its evaluation?

    2023  Band 9

    Abstract: Abstract Background Sarcoidosis is a multisystem disease defined by non-caseous epithelioid cell granulomas that can affect virtually all organs. Lung, mediastinal and hilar lymph node involvement is prevalent, occurring in around 90% of the patients, ... ...

    Abstract Abstract Background Sarcoidosis is a multisystem disease defined by non-caseous epithelioid cell granulomas that can affect virtually all organs. Lung, mediastinal and hilar lymph node involvement is prevalent, occurring in around 90% of the patients, and is responsible for the majority of the morbidity and mortality related to the disorder. Sarcoidosis is one of the differential diagnoses of the benign mediastinal lymphadenopathy. This research aimed to detect the diagnostic value of magnetic resonance imaging (MRI) diffusion in evaluation of mediastinal lymphadenopathy in sarcoid patients. Results This cross study involved a total of 30 patients known to have sarcoidosis: 6 males and 24 females aged between 18 and 50 years (with a mean age 38.97 ± 8.67); all of them presented with mediastinal lymphadenopathy. For all patients, each lymph node group was evaluated for the average size and average ADC value. The mean ADC measured was (1.76 ± 0.28) × 10−3 mm2/s. Eight patients showed concurrent activity with poor response to the treatment, and they showed different ADC values with one of them showing low ADC with pattern of diffusion restriction displaying mean ADC value of 1.28 × 10−3 mm2/s. Conclusions Diffusion-weighted MRI is an established imaging technique that could be utilized to evaluate mediastinal lymphadenopathy in sarcoidosis as the benign counterpart of mediastinal lymphadenopathy.
    Schlagwörter Sarcoidosis ; Mediastinal lymphadenopathy ; MRI diffusion ; ADC value ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2023-03-01T00:00:00Z
    Verlag SpringerOpen
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Artikel ; Online: MR diffusion imaging in mediastinal masses the differentiation between benign and malignant lesions

    Youssriah Yahia Sabri / Marian Fayek Farid Kolta / Mostafa Ahmed Khairy

    The Egyptian Journal of Radiology and Nuclear Medicine, Vol 48, Iss 3, Pp 569-

    2017  Band 580

    Abstract: Background: Diffusion-weighted imaging is a fundamental tool integrated in MR protocols useful in differentiating benign from malignant mediastinal masses, assessing mediastinal lymphadenopathy and investigating central bronchogenic carcinoma. This ... ...

    Abstract Background: Diffusion-weighted imaging is a fundamental tool integrated in MR protocols useful in differentiating benign from malignant mediastinal masses, assessing mediastinal lymphadenopathy and investigating central bronchogenic carcinoma. This method is an excellent alternative to CT or PET/CT in the investigation of mediastinal masses. Current applications of diffusion MRI in malignancies include monitoring the treatment response and detecting recurrent cancer. Aim of the work: This study aims to assess the value of using MRI diffusion in differentiating benign and malignant mediastinal masses, differentiating central masses from post obstructive collapse and differentiating lymphoma versus sarcoidosis. Patients and methods: This study included 30 patients; 16 males and 14 females in the period from June 2013 to July 2014. The mean age was 49.3 ± 16.85 (range: 22â82 years).Cases were referred for MRI assessment and were approved by the ethical committee in our department.The complaints varied between dyspnea, chest pain, cough, hemoptysis, fatigue and loss of weight. A superconducting 1.5 T MRI machine with a four-channel body phased-array coil was used for the examination. Biopsy and histopathological assessment was done after that. Results: MRI examination with diffusion imaging was able to differentiate between benign and malignant mediastinal and hilar lesion confirmed by the biopsy and histopathology. Conclusion: MRI with diffusion weighted images can detect and stage lung cancer, differentiate benign from malignant mediastinal masses and differentiate lymphoma from sarcoidosis in mediastinal/hilar lymphadenopathy. Keywords: Magnetic resonance imaging, Diffusion, Sarcoidosis, Lymphoma, Bronchogenic carcinoma
    Schlagwörter Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2017-09-01T00:00:00Z
    Verlag SpringerOpen
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  7. Artikel ; Online: CT chest for COVID-19, a multicenter study—experience with 220 Egyptian patients

    Youssriah Yahia Sabri / Amr A. Nassef / Iman Mohamed Hamdy Ibrahim / Mohammed Raafat Abd El Mageed / Mostafa Ahmed Khairy

    The Egyptian Journal of Radiology and Nuclear Medicine, Vol 51, Iss 1, Pp 1-

    2020  Band 15

    Abstract: Abstract Background COVID-19 has become a national and an international pre-occupation to all doctors. Dealing with patients with clinical suspicion of COVID-19 is a daily markedly growing professional issue for radiologists. The number of COVID-19 cases ...

    Abstract Abstract Background COVID-19 has become a national and an international pre-occupation to all doctors. Dealing with patients with clinical suspicion of COVID-19 is a daily markedly growing professional issue for radiologists. The number of COVID-19 cases we deal with is peaking since last March and so is our experience in recognizing the disease patterns and in assessing its severity. The purpose of this study is to assess the role of CT chest in the diagnosis of COVID-19 based on our experience with 220 Egyptian cases. Results A cross-sectional multicenter study involving 220 patients; 68 (30.9%) females and 152 (69.1%) males, their age range was 10-92 years (average 49.198 years). Non-contrast MSCT chest was done to patients with clinically suspected COVID-19. Data assessment and analysis for lesions probability, pattern, localization, and severity were done. Bilateral affection was seen in 168/220 cases (76.36%). Multilobar affection was noted in 186/220 cases (84.54%). Lower lobes affection was noted in 179/220 cases (81.36%). Peripheral/subpleural affection was noted in 203/220 cases (92.27%). The common CT patterns (ground-glass opacities, consolidation, crazy paving, vascular thickening, traction bronchiectasis, vacuolar sign, architectural distortion signs, and reversed halo sign) and the uncommon CT patterns (halo sign, masses, nodules, lobar affection, tree in-bud-pattern and cysts) were discussed. Associated extra-pulmonary lesions described. Temporal changes, severity scoring, reporting, and possible pitfalls were all assessed. Conclusion In our experience, CT plays a basic essential role in diagnosing COVID-19 in the current declared pandemic.
    Schlagwörter CT chest ; COVID-19 ; Common patterns ; Uncommon patterns ; Severity score ; Temporal changes ; Medical physics. Medical radiology. Nuclear medicine ; R895-920 ; covid19
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2020-07-01T00:00:00Z
    Verlag SpringerOpen
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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