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  1. Article ; Online: Iran's experience in controlling and managing COVID-19

    Mina Moeini / Kamal Heidari / Mostafa Rezaee / Asefeh Hadadpour / Zahra Amini

    Journal of Research in Medical Sciences, Vol 26, Iss 1, Pp 100-

    A lesson for developing countries

    2021  Volume 100

    Keywords Medicine ; R
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Clinical symptoms of COVID-19 and their association with disease outcome

    Negah Tavakolifard / Mina Moeini / Asefeh Haddadpoor / Kamal Heidari / Mostafa Rezaee / Zahra Amini

    Advanced Biomedical Research, Vol 11, Iss 1, Pp 2-

    2022  Volume 2

    Abstract: Background: COVID-19 pandemic placed immense pressure on health systems. The current study aimed to evaluate the symptoms of COVID-19 in Isfahan province and their association with disease outcome. Materials and Methods: In this cross-sectional study, ... ...

    Abstract Background: COVID-19 pandemic placed immense pressure on health systems. The current study aimed to evaluate the symptoms of COVID-19 in Isfahan province and their association with disease outcome. Materials and Methods: In this cross-sectional study, which was conducted on patients with a definite diagnosis of COVID-19, as a part of the investigations performed by the Deputy for Public Health of the Isfahan University of Medical Sciences, the frequency of underlying diseases, and general, respiratory, gastrointestinal, neurological, renal, cardiac, dermal, hearing symptoms are assessed using a checklist. The participants were followed up 1 month after definitive diagnosis, and the outcome of the disease (recovery or death) was recorded. Results: Of 300 patients, 143 (47.4%) were male and 157 (52.6%) were female. The mean age of patients was 43 ± 17.84 years. Muscle pain and fatigue were the most common early symptoms (63% and 60.3%, respectively). Age, sex, level of education, and occupation of patients and general, respiratory, and gastrointestinal symptoms and underlying diseases of respiratory disease showed a statistically significant association with the disease outcome (P < 0.05). Conclusion: General, respiratory, and gastrointestinal symptoms were associated with an increased risk of death due to COVID-19. General, visual, and hearing symptoms, and diabetes, cardiovascular diseases, and respiratory disease had a statistically significant association with the hospitalization of patients.
    Keywords signs and symptoms ; covid-19 ; death ; hospitalization ; Medicine ; R ; Biology (General) ; QH301-705.5
    Subject code 610
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Prevalence of Oral and Craniofacial Manifestations of Hematological Dyscrasias at Shiraz Nemazee Hospital

    Janan Ghapanchi / Mostafa Rezaee / Fereshteh Kamali / Fatemeh Lavaee / Eissa Shakib

    Middle East Journal of Cancer , Vol 5, Iss 3, Pp 145-

    2014  Volume 149

    Abstract: Background: Hematological disorders may present with a number of non-specific orofacial manifestations that must be diagnosed and referred to specialists for treatment. Since the orofacial manifestations can be the first clinical presentation which ... ...

    Abstract Background: Hematological disorders may present with a number of non-specific orofacial manifestations that must be diagnosed and referred to specialists for treatment. Since the orofacial manifestations can be the first clinical presentation which indicates the presence of an underlying disease, it is important for dentists to be aware of these manifestations. The present study aims to evaluate the orofacial presentations of some hematological diseases in order to familiarize dentists with these manifestations. Methods: This descriptive cross-sectional study evaluated the oral conditions of patients recently hospitalized with histories of blood dyscrasia and bone marrow transplantation in Shiraz Nemazee Hospital during 2010-2011. From 50 patients, there were 33 (66%) males and 17 (34%) females. The age of participants ranged from 12-77 years of age. Results: Examined patients had the following manifestations: head and neck region lymphadenopathy (42%), hairy tongue, atrophy of the oral mucosa, ulcers, red and white lesions, Candida albicans infection and gingival lesions that included spontaneous gingival bleeding, gingival hypertrophy and ecchymosis, in addition to diffuse herpetic infections on the buccal mucosa and bony lesions. The most common blood dyscrasia in the study patients was acute myeloid leukemia (AML) (48%). Our findings determined that lymphadenopathy (42%) was the most common orofacial manifestation of hematological diseases. Conclusion:On occasion, dentists maybe the first medical professional to encounter hematological diseases. Since early detection of these disorders can increase patient survival, it is necessary for dentists to become completely familiar with these oral manifestations.
    Keywords Oral manifestation ; Leukemia ; Thalassemia ; Hematologic dyscrasias ; Neoplasms. Tumors. Oncology. Including cancer and carcinogens ; RC254-282 ; Internal medicine ; RC31-1245 ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2014-07-01T00:00:00Z
    Publisher Shiraz University of Medical Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Comparison of univariate and multivariate gene set analysis in acute lymphoblastic leukemia.

    Soheila, Khodakarim / Hamid, Alavimajd / Farid, Zayeri / Mostafa, Rezaee-Tavirani / Nasrin, Dehghan-Nayeri / Syyed-Mohammad, Tabatabaee / Vahide, Tajalli

    Asian Pacific journal of cancer prevention : APJCP

    2013  Volume 14, Issue 3, Page(s) 1629–1633

    Abstract: Background: Gene set analysis (GSA) incorporates biological with statistical knowledge to identify gene sets which are differentially expressed that between two or more phenotypes.: Materials and methods: In this paper gene sets differentially ... ...

    Abstract Background: Gene set analysis (GSA) incorporates biological with statistical knowledge to identify gene sets which are differentially expressed that between two or more phenotypes.
    Materials and methods: In this paper gene sets differentially expressed between acute lymphoblastic leukaemia (ALL) with BCR-ABL and those with no observed cytogenetic abnormalities were determined by GSA methods. The BCR-ABL is an abnormal gene found in some people with ALL.
    Results: The results of two GSAs showed that the Category test identified 30 gene sets differentially expressed between two phenotypes, while the Hotelling's T2 could discover just 19 gene sets. On the other hand, assessment of common genes among significant gene sets showed that there were high agreement between the results of GSA and the findings of biologists. In addition, the performance of these methods was compared by simulated and ALL data.
    Conclusions: The results on simulated data indicated decrease in the type I error rate and increase the power in multivariate (Hotelling's T2) test as increasing the correlation between gene pairs in contrast to the univariate (Category) test.
    MeSH term(s) Biomarkers, Tumor/genetics ; Follow-Up Studies ; Fusion Proteins, bcr-abl/genetics ; Gene Expression Profiling ; Humans ; Oligonucleotide Array Sequence Analysis ; Phenotype ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/metabolism ; Prognosis
    Chemical Substances Biomarkers, Tumor ; Fusion Proteins, bcr-abl (EC 2.7.10.2)
    Language English
    Publishing date 2013-05-15
    Publishing country Thailand
    Document type Comparative Study ; Journal Article
    ZDB-ID 2218955-5
    ISSN 2476-762X ; 1513-7368
    ISSN (online) 2476-762X
    ISSN 1513-7368
    DOI 10.7314/apjcp.2013.14.3.1629
    Database MEDical Literature Analysis and Retrieval System OnLINE

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