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  1. Article ; Online: Ventilatory support recommendations in children with Sars-CoV-2.

    Carvalho, Werther Brunow de / Rodriguez, Isadora Souza / Motta, Emiliana Holzhausen Gonçalves da / Delgado, Artur Figueiredo

    Revista da Associacao Medica Brasileira (1992)

    2020  Volume 66, Issue 4, Page(s) 528–533

    MeSH term(s) Airway Management/methods ; Analgesics/administration & dosage ; Betacoronavirus ; COVID-19 ; Child ; Contraindications, Procedure ; Coronavirus Infections/complications ; Coronavirus Infections/diagnostic imaging ; Coronavirus Infections/epidemiology ; Coronavirus Infections/therapy ; Humans ; Hypnotics and Sedatives/administration & dosage ; Hypoxia/therapy ; Lung/diagnostic imaging ; Neuromuscular Blocking Agents/administration & dosage ; Nitric Oxide/therapeutic use ; Noninvasive Ventilation/methods ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnostic imaging ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/therapy ; Prone Position ; Respiration, Artificial/adverse effects ; Respiration, Artificial/methods ; Respiratory Insufficiency/diagnostic imaging ; Respiratory Insufficiency/etiology ; Respiratory Insufficiency/therapy ; SARS-CoV-2 ; Ventilator Weaning
    Chemical Substances Analgesics ; Hypnotics and Sedatives ; Neuromuscular Blocking Agents ; Nitric Oxide (31C4KY9ESH)
    Keywords covid19
    Language English
    Publishing date 2020-06-22
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 731969-1
    ISSN 1806-9282 ; 0104-4230 ; 0004-5241 ; 0102-843X
    ISSN (online) 1806-9282
    ISSN 0104-4230 ; 0004-5241 ; 0102-843X
    DOI 10.1590/1806-9282.66.4.528
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Beyond ventilatory support

    Ferranti, Juliana Ferreira / Rodriguez, Isadora Souza / Motta, Emiliana / Johnston, Cíntia / Carvalho, Werther Brunow de B. / Delgado, Artur Figueiredo

    Revista da Associação Médica Brasileira v.66 n.4 2020

    challenges in general practice and in the treatment of critically Ill children and adolescents with SARS-CoV-2 infection

    2020  

    Abstract: SUMMARY Severe acute respiratory syndrome coronavirus 2 (Sars-CoV-2 infection) is a new challenge for all countries, and children are predisposed to acquire this disease. Some studies have demonstrated more severe diseases in adults, but critically ill ... ...

    Abstract SUMMARY Severe acute respiratory syndrome coronavirus 2 (Sars-CoV-2 infection) is a new challenge for all countries, and children are predisposed to acquire this disease. Some studies have demonstrated more severe diseases in adults, but critically ill pediatric patients have been described in all ages. Pulmonary involvement is the major feature, and ventilatory support is common in critical cases. Nevertheless, other very important therapeutic approaches must be considered. In this article, we reviewed extensively all recent medical literature to point out the main clinical attitudes to support these pediatric patients during their period in respiratory support. Radiologic findings, fluid therapy, hemodynamic support, use of inotropic/vasopressors, nutritional therapy, antiviral therapy, corticosteroids, antithrombotic therapy, and immunoglobulins are analyzed to guide all professionals during hospitalization. We emphasize the importance of a multi-professional approach for adequate recovery.
    Keywords Child ; Coronavirus ; Sars-CoV-2 ; COVID-19 ; covid19
    Subject code 610
    Language English
    Publishing date 2020-04-01
    Publisher Associação Médica Brasileira
    Publishing country br
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Ventilatory support recommendations in children with Sars-CoV-2

    Carvalho, Werther Brunow de / Rodriguez, Isadora Souza / Motta, Emiliana Holzhausen Gonçalves da / Delgado, Artur Figueiredo

    Revista da Associação Médica Brasileira v.66 n.4 2020

    2020  

    Keywords Sars-CoV-2 ; critically ill patients ; mechanical ventilation ; respiratory support ; children ; adolescents ; covid19
    Language English
    Publishing date 2020-04-01
    Publisher Associação Médica Brasileira
    Publishing country br
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Beyond ventilatory support: challenges in general practice and in the treatment of critically Ill children and adolescents with SARS-CoV-2 infection.

    Ferranti, Juliana Ferreira / Rodriguez, Isadora Souza / Motta, Emiliana / Johnston, Cíntia / Carvalho, Werther Brunow de B / Delgado, Artur Figueiredo

    Revista da Associacao Medica Brasileira (1992)

    2020  Volume 66, Issue 4, Page(s) 521–527

    Abstract: Severe acute respiratory syndrome coronavirus 2 (Sars-CoV-2 infection) is a new challenge for all countries, and children are predisposed to acquire this disease. Some studies have demonstrated more severe diseases in adults, but critically ill pediatric ...

    Abstract Severe acute respiratory syndrome coronavirus 2 (Sars-CoV-2 infection) is a new challenge for all countries, and children are predisposed to acquire this disease. Some studies have demonstrated more severe diseases in adults, but critically ill pediatric patients have been described in all ages. Pulmonary involvement is the major feature, and ventilatory support is common in critical cases. Nevertheless, other very important therapeutic approaches must be considered. In this article, we reviewed extensively all recent medical literature to point out the main clinical attitudes to support these pediatric patients during their period in respiratory support. Radiologic findings, fluid therapy, hemodynamic support, use of inotropic/vasopressors, nutritional therapy, antiviral therapy, corticosteroids, antithrombotic therapy, and immunoglobulins are analyzed to guide all professionals during hospitalization. We emphasize the importance of a multi-professional approach for adequate recovery.
    MeSH term(s) Adolescent ; Betacoronavirus ; COVID-19 ; Child ; Coronavirus Infections/therapy ; Critical Illness ; Fluid Therapy/methods ; General Practice/methods ; Hemodynamic Monitoring/methods ; Humans ; Nutrition Therapy/methods ; Pandemics ; Physical Therapy Modalities ; Pneumonia, Viral/therapy ; Respiration, Artificial/methods ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-06-22
    Publishing country Brazil
    Document type Journal Article ; Review
    ZDB-ID 731969-1
    ISSN 1806-9282 ; 0104-4230 ; 0004-5241 ; 0102-843X
    ISSN (online) 1806-9282
    ISSN 0104-4230 ; 0004-5241 ; 0102-843X
    DOI 10.1590/1806-9282.66.4.521
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Importance of the use of protocols for the management of analgesia and sedation in pediatric intensive care unit.

    Motta, Emiliana / Luglio, Michele / Delgado, Artur Figueiredo / Carvalho, Werther Brunow de

    Revista da Associacao Medica Brasileira (1992)

    2016  Volume 62, Issue 6, Page(s) 602–609

    Abstract: Introduction:: Analgesia and sedation are essential elements in patient care in the intensive care unit (ICU), in order to promote the control of pain, anxiety and agitation, prevent the loss of devices, accidental extubation, and improve the synchrony ... ...

    Abstract Introduction:: Analgesia and sedation are essential elements in patient care in the intensive care unit (ICU), in order to promote the control of pain, anxiety and agitation, prevent the loss of devices, accidental extubation, and improve the synchrony of the patient with mechanical ventilation. However, excess of these medications leads to rise in morbidity and mortality. The ideal management will depend on the adoption of clinical and pharmacological measures, guided by scales and protocols.
    Objective:: Literature review on the main aspects of analgesia and sedation, abstinence syndrome, and delirium in the pediatric intensive care unit, in order to show the importance of the use of protocols on the management of critically ill patients.
    Method:: Articles published in the past 16 years on PubMed, Lilacs, and the Cochrane Library, with the terms analgesia, sedation, abstinence syndrome, mild sedation, daily interruption, and intensive care unit.
    Results:: Seventy-six articles considered relevant were selected to describe the importance of using a protocol of sedation and analgesia. They recommended mild sedation and the use of assessment scales, daily interruptions, and spontaneous breathing test. These measures shorten the time of mechanical ventilation, as well as length of hospital stay, and help to control abstinence and delirium, without increasing the risk of morbidity and morbidity.
    Conclusion:: Despite the lack of controlled and randomized clinical trials in the pediatric setting, the use of protocols, optimizing mild sedation, leads to decreased morbidity.
    MeSH term(s) Analgesia/methods ; Analgesics/administration & dosage ; Child ; Clinical Protocols/standards ; Critical Illness ; Delirium/prevention & control ; Humans ; Hypnotics and Sedatives/administration & dosage ; Intensive Care Units, Pediatric ; Male ; Substance Withdrawal Syndrome/prevention & control
    Chemical Substances Analgesics ; Hypnotics and Sedatives
    Language English
    Publishing date 2016-11-16
    Publishing country Brazil
    Document type Journal Article ; Review
    ZDB-ID 731969-1
    ISSN 1806-9282 ; 0104-4230 ; 0004-5241 ; 0102-843X
    ISSN (online) 1806-9282
    ISSN 0104-4230 ; 0004-5241 ; 0102-843X
    DOI 10.1590/1806-9282.62.06.602
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Ventilatory support recommendations in children with Sars-CoV-2

    Carvalho, Werther Brunow de / Rodriguez, Isadora Souza / Motta, Emiliana Holzhausen Goncalves da / Delgado, Artur Figueiredo

    Revista da Associacao Medica Brasileira (1992)

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #613695
    Database COVID19

    Kategorien

  7. Article ; Online: Opioid tapering and weaning protocols in pediatric critical care units: a systematic review.

    Bichaff, Pedro / Setani, Karina T / Motta, Emiliana H G / Delgado, Artur F / Carvalho, Werther B / Luglio, Michele

    Revista da Associacao Medica Brasileira (1992)

    2018  Volume 64, Issue 10, Page(s) 909–915

    Abstract: Objective: Opioid abstinence syndrome is common in the pediatric intensive care environment because sedation is often needed during the children's treatment. There is no specific guideline regarding the management of these patients; and lately, ... ...

    Abstract Objective: Opioid abstinence syndrome is common in the pediatric intensive care environment because sedation is often needed during the children's treatment. There is no specific guideline regarding the management of these patients; and lately, methadone is an important drug for the prevention of abstinence symptoms during the weaning of opioids. This study gathers the available research to establish the initial dose of methadone, the rate of taper and tools to recognize this syndrome and act promptly.
    Methods: A systematic review was made from data of four different databases. Forty-nine articles of observational and experimental studies were selected based on the inclusion criteria (critical pediatric patients in acute use of opioids) and exclusion criteria (previous chronic use of opioids, other medications). The data regarding specific themes were separated in sections: initial dose of methadone, use of protocols in clinical practice, abstinence scales and adjuvant drugs.
    Results: The articles showed a great heterogeneity of ways to calculate the initial dose of methadone. The pediatric intensive care units of the study had different weaning protocols, with a lower incidence of abstinence when a pre-defined sequence of tapering was used. The Withdrawal Assessment Tool - 1 was the most used scale for tapering the opioids, with good sensitivity and specificity for signs and symptoms.
    Conclusion: There is still little evidence of other medications that can help prevent the abstinence syndrome of opioids. This study tries to promote a better practice during opioid weaning.
    MeSH term(s) Analgesics, Opioid/administration & dosage ; Analgesics, Opioid/adverse effects ; Child ; Critical Care/methods ; Humans ; Intensive Care Units, Pediatric ; Methadone/administration & dosage ; Substance Withdrawal Syndrome/therapy
    Chemical Substances Analgesics, Opioid ; Methadone (UC6VBE7V1Z)
    Language English
    Publishing date 2018-12-03
    Publishing country Brazil
    Document type Journal Article ; Systematic Review
    ZDB-ID 2027973-5
    ISSN 1806-9282 ; 0104-4230
    ISSN (online) 1806-9282
    ISSN 0104-4230
    DOI 10.1590/1806-9282.64.10.909
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Beyond ventilatory support: challenges in general practice and in the treatment of critically Ill children and adolescents with SARS-CoV-2 infection

    Ferranti, Juliana Ferreira / Rodriguez, Isadora Souza / Motta, Emiliana / Johnston, Cintia / Carvalho, Werther Brunow de B. / Delgado, Artur Figueiredo

    Revista da Associacao Medica Brasileira (1992)

    Abstract: Severe acute respiratory syndrome coronavirus 2 (Sars-CoV-2 infection) is a new challenge for all countries, and children are predisposed to acquire this disease Some studies have demonstrated more severe diseases in adults, but critically ill pediatric ... ...

    Abstract Severe acute respiratory syndrome coronavirus 2 (Sars-CoV-2 infection) is a new challenge for all countries, and children are predisposed to acquire this disease Some studies have demonstrated more severe diseases in adults, but critically ill pediatric patients have been described in all ages Pulmonary involvement is the major feature, and ventilatory support is common in critical cases Nevertheless, other very important therapeutic approaches must be considered In this article, we reviewed extensively all recent medical literature to point out the main clinical attitudes to support these pediatric patients during their period in respiratory support Radiologic findings, fluid therapy, hemodynamic support, use of inotropic/vasopressors, nutritional therapy, antiviral therapy, corticosteroids, antithrombotic therapy, and immunoglobulins are analyzed to guide all professionals during hospitalization We emphasize the importance of a multi-professional approach for adequate recovery
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #613692
    Database COVID19

    Kategorien

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