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  1. Article ; Online: Objective assessment of intraoperative skills for robot-assisted partial nephrectomy (RAPN).

    Farinha, Rui / Breda, Alberto / Porter, James / Mottrie, Alexandre / Van Cleynenbreugel, Ben / Vander Sloten, Jozef / Mottaran, Angelo / Gallagher, Anthony G

    Journal of robotic surgery

    2023  Volume 17, Issue 4, Page(s) 1401–1409

    Abstract: RAPN training usually takes place in-vivo and methods vary across countries/institutions. No common system exists to objectively assess trainee capacity to perform RAPN at predetermined performance levels prior to in-vivo practice. The identification of ... ...

    Abstract RAPN training usually takes place in-vivo and methods vary across countries/institutions. No common system exists to objectively assess trainee capacity to perform RAPN at predetermined performance levels prior to in-vivo practice. The identification of objective performance metrics for RAPN training is a crucial starting point to improve training and surgical outcomes. The authors sought to examine the reliability, construct and discriminative validity of objective intraoperative performance metrics which best characterize the optimal and suboptimal performance of a reference approach for training novice RAPN surgeons. Seven Novice and 9 Experienced RAPN surgeons video recorded one or two independently performed RAPN procedures in the human. The videos were anonymized and two experienced urology surgeons were trained to reliably score RAPN performance, using previously developed metrics. The assessors were blinded to the performing surgeon, hospital and surgeon group. They independently scored surgeon RAPN performance. Novice and Experienced group performance scores were compared for procedure steps completed and errors made. Each group was divided at the median for Total Errors score, and subgroup scores (i.e., Novice HiErrs and LoErrs, Experienced HiErrs and LoErrs) were compared. The mean inter-rater reliability (IRR) for scoring was 0.95 (range 0.84-1). Compared with Novices, Experienced RAPN surgeons made 69% fewer procedural Total Errors. This difference was accentuated when the LoErr Expert RAPN surgeon's performance was compared with the HiErrs Novice RAPN surgeon's performance with an observed 170% fewer Total Errors. GEARS showed poor reliability (Mean IRR = 0.44; range 0.0-0.8), for scoring RAPN surgical performance. The RAPN procedure metrics reliably distinguish Novice and Experienced surgeon performances. They further differentiated performance levels within a group with similar experiences. Reliable and valid metrics will underpin quality-assured novice RAPN surgical training.
    MeSH term(s) Humans ; Robotic Surgical Procedures/methods ; Robotics ; Reproducibility of Results ; Surgeons ; Clinical Competence ; Nephrectomy/education
    Language English
    Publishing date 2023-01-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2268283-1
    ISSN 1863-2491 ; 1863-2483
    ISSN (online) 1863-2491
    ISSN 1863-2483
    DOI 10.1007/s11701-023-01521-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Development and validation of metrics for a new RAPN training model.

    Dos Santos Almeida Farinha, Rui Jorge / Piro, Adele / Mottaran, Angelo / Paciotti, Marco / Puliatti, Stefano / Breda, Alberto / Porter, James / Van Cleynenbreugel, Ben / Vander Sloten, Jos / Mottrie, Alexandre / Gallagher, Anthony G

    Journal of robotic surgery

    2024  Volume 18, Issue 1, Page(s) 153

    Abstract: Robot-assisted partial nephrectomy (RAPN) is a complex and index procedure that urologists need to learn how to perform safely. No validated performance metrics specifically developed for a RAPN training model (TM) exist. A Core Metrics Group ... ...

    Abstract Robot-assisted partial nephrectomy (RAPN) is a complex and index procedure that urologists need to learn how to perform safely. No validated performance metrics specifically developed for a RAPN training model (TM) exist. A Core Metrics Group specifically adapted human RAPN metrics to be used in a newly developed RAPN TM, explicitly defining phases, steps, errors, and critical errors. A modified Delphi meeting concurred on the face and content validation of the new metrics. One hundred percent consensus was achieved by the Delphi panel on 8 Phases, 32 Steps, 136 Errors and 64 Critical Errors. Two trained assessors evaluated recorded video performances of novice and expert RAPN surgeons executing an emulated RAPN in the newly developed TM. There were no differences in procedure Steps completed by the two groups. Experienced RAPN surgeons made 34% fewer Total Errors than the Novice group. Performance score for both groups was divided at the median score using Total Error scores, into HiError and LoError subgroups. The LowErrs Expert RAPN surgeons group made 118% fewer Total Errors than the Novice HiErrs group. Furthermore, the LowErrs Expert RAPN surgeons made 77% fewer Total Errors than the HiErrs Expert RAPN surgeons. These results established construct and discriminative validity of the metrics. The authors described a novel RAPN TM and its associated performance metrics with evidence supporting their face, content, construct, and discriminative validation. This report and evidence support the implementation of a simulation-based proficiency-based progression (PBP) training program for RAPN.
    MeSH term(s) Humans ; Robotic Surgical Procedures/methods ; Learning ; Benchmarking ; Blood Transfusion ; Nephrectomy
    Language English
    Publishing date 2024-04-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2268283-1
    ISSN 1863-2491 ; 1863-2483
    ISSN (online) 1863-2491
    ISSN 1863-2483
    DOI 10.1007/s11701-024-01911-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: International Expert Consensus on Metric-based Characterization of Robot-assisted Partial Nephrectomy.

    Farinha, Rui / Breda, Alberto / Porter, James / Mottrie, Alexandre / Van Cleynenbreugel, Ben / Vander Sloten, Jozef / Mottaran, Angelo / Gallagher, Anthony G

    European urology focus

    2022  Volume 9, Issue 2, Page(s) 388–395

    Abstract: Background: Robot-assisted partial nephrectomy (RAPN) training usually takes place in vivo, and methods vary across countries/institutions. No common system exists to objectively assess trainee ability to perform RAPN at predetermined performance levels ...

    Abstract Background: Robot-assisted partial nephrectomy (RAPN) training usually takes place in vivo, and methods vary across countries/institutions. No common system exists to objectively assess trainee ability to perform RAPN at predetermined performance levels prior to in vivo practice. The identification of objective performance metrics for RAPN training is a crucial starting point to improve training and surgical outcomes.
    Objective: We sought to identify objective performance metrics that best characterize a reference approach to RAPN, and obtain face and content validity from procedure experts through a modified Delphi meeting.
    Design, setting, and participants: During a series of online meetings, a core metrics team of three RAPN experts and a senior behavioral scientist performed a detailed task deconstruction of a transperitoneal left-sided RAPN procedure.
    Outcome measurements and statistical analysis: Based on published guidelines, manufacturers' instructions, and unedited videos of RAPN, the team identified performance metrics that constitute an optimal approach for training purposes. The metrics were then subjected to an in-person modified international Delphi panel meeting with 19 expert surgeons.
    Results and limitations: Eleven procedure phases, with 64 procedure steps, 43 errors, and 39 critical errors, were identified. After the modified Delphi process, the international expert panel added 13 metrics (two steps), six were deleted, and three were modified; 100% panel consensus on the resulting metrics was obtained. Limitations are that the metrics are applicable only to left-sided RAPN cases and some might have been excluded.
    Conclusions: Performance metrics that accurately characterize RAPN procedure were developed by a core group of experts. The metrics were then presented to and endorsed by an international panel of very experienced peers. Reliable and valid metrics underpin effective, quality-assured, structured surgical training for RAPN.
    Patient summary: We organize a meeting among robot-assisted partial nephrectomy (RAPN) experts to identify and reach consensus on objective performance metrics for RAPN training. The metrics are a crucial starting point to improve and quality assure surgical training and patients' clinical outcomes.
    MeSH term(s) Humans ; Robotics ; Consensus ; Robotic Surgical Procedures/methods ; Nephrectomy/methods ; Laparoscopy
    Language English
    Publishing date 2022-10-10
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2405-4569
    ISSN (online) 2405-4569
    DOI 10.1016/j.euf.2022.09.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Urological surgery with the Hugo RAS™ System: insights into system adaptability.

    Paciotti, Marco / Bravi, Carlo A / Piramide, Federico / Mottaran, Angelo / Sarchi, Luca / Dell'oglio, Paolo / Turri, Filippo / DI Maida, Fabrizio / Liakos, Nikolaos / Andras, Iulia / Covas Moschovas, Marcio / Wenzel, Mike / Sorce, Gabriele / Wurnschimmel, Christoph / Lambert, Edward / DE Groote, Ruben / Larcher, Alessandro

    Minerva urology and nephrology

    2024  Volume 76, Issue 2, Page(s) 267–270

    MeSH term(s) Humans ; Urologic Surgical Procedures/instrumentation
    Language English
    Publishing date 2024-05-06
    Publishing country Italy
    Document type Letter ; Journal Article
    ZDB-ID 3062840-4
    ISSN 2724-6442
    ISSN (online) 2724-6442
    DOI 10.23736/S2724-6051.24.05879-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Twenty Years' Experience in Retroperitoneal Lymph Node Dissection for Testicular Cancer in a Tertiary Referral Center.

    Mottaran, Angelo / Ercolino, Amelio / Bianchi, Lorenzo / Piazza, Pietro / Manes, Francesco / Amirhassankhani, Sasan / Salvador, Marco / Chessa, Francesco / Corcioni, Beniamino / Bertaccini, Alessandro / Schiavina, Riccardo / Brunocilla, Eugenio

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 1

    Abstract: Background and ... ...

    Abstract Background and Objectives
    MeSH term(s) Male ; Humans ; Testicular Neoplasms ; Tertiary Care Centers ; Retroperitoneal Space/surgery ; Retroperitoneal Space/pathology ; Retrospective Studies ; Lymph Node Excision/methods ; Neoplasm Staging ; Treatment Outcome
    Language English
    Publishing date 2023-01-10
    Publishing country Switzerland
    Document type Review ; Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59010133
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  6. Article ; Online: A Novel Three-dimensional Planning Tool for Selective Clamping During Partial Nephrectomy: Validation of a Perfusion Zone Algorithm.

    De Backer, Pieter / Vermijs, Saar / Van Praet, Charles / De Visschere, Pieter / Vandenbulcke, Sarah / Mottaran, Angelo / Bravi, Carlo A / Berquin, Camille / Lambert, Edward / Dautricourt, Stéphanie / Goedertier, Wouter / Mottrie, Alexandre / Debbaut, Charlotte / Decaestecker, Karel

    European urology

    2023  Volume 83, Issue 5, Page(s) 413–421

    Abstract: Background: Selective clamping during robot-assisted partial nephrectomy (RAPN) requires extensive knowledge on patient-specific renal vasculature, obtained through imaging.: Objective: To validate an in-house developed perfusion zone algorithm that ... ...

    Abstract Background: Selective clamping during robot-assisted partial nephrectomy (RAPN) requires extensive knowledge on patient-specific renal vasculature, obtained through imaging.
    Objective: To validate an in-house developed perfusion zone algorithm that provides patient-specific three-dimensional (3D) renal perfusion information.
    Design, setting, and participants: Between October 2020 and June 2022, 25 patients undergoing RAPN at Ghent University Hospital were included. Three-dimensional models, based on preoperative computed tomography (CT) scans, showed the clamped artery's ischemic zone, as calculated by the algorithm.
    Surgical procedure: All patients underwent selective clamping during RAPN. Indocyanine green (ICG) was administered to visualize the true ischemic zone perioperatively. Surgery was recorded for a postoperative analysis.
    Measurements: The true ischemic zone of the clamped artery was compared with the ischemic zone predicted by the algorithm through two metrics: (1) total ischemic zone overlap and (2) tumor ischemic zone overlap. Six urologists assessed metric 1; metric 2 was assessed objectively by the authors.
    Results and limitations: In 92% of the cases, the algorithm was sufficiently accurate to plan a selective clamping strategy. Metric 1 showed an average score of 4.28 out of 5. Metric 2 showed an average score of 4.14 out of 5. A first limitation is that ICG can be evaluated only at the kidney surface. A second limitation is that mainly patients with impaired renal function are expected to benefit from this technology, but contrast-enhanced CT is required at present.
    Conclusions: The proposed new tool demonstrated high accuracy when planning selective clamping for RAPN. A follow-up prospective study is needed to determine the tool's clinical added value.
    Patient summary: In partial nephrectomy, the surgeon has no information on which specific arterial branches perfuse the kidney tumor. We developed a surgeon support system that visualizes the perfusion zones of all arteries on a three-dimensional model and indicates the correct arteries to clamp. In this study, we validate this tool.
    MeSH term(s) Humans ; Constriction ; Nephrectomy/methods ; Kidney/diagnostic imaging ; Kidney/surgery ; Kidney Neoplasms/diagnostic imaging ; Kidney Neoplasms/surgery ; Kidney Neoplasms/blood supply ; Robotic Surgical Procedures/methods ; Perfusion ; Indocyanine Green ; Algorithms ; Treatment Outcome ; Retrospective Studies
    Chemical Substances Indocyanine Green (IX6J1063HV)
    Language English
    Publishing date 2023-02-01
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2023.01.003
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  7. Article ; Online: Techniques and outcomes of robot-assisted partial nephrectomy for the treatment of multiple ipsilateral renal masses.

    Buffi, Nicolomaria / Uleri, Alessandro / Paciotti, Marco / Lughezzani, Giovanni / Casale, Paolo / Diana, Pietro / DE Groote, Ruben / Sarchi, Luca / Mottaran, Angelo / Bravi, Carlo / DE Backer, Pieter / Amparore, Daniele / Fiori, Cristian / Porpiglia, Francesco / Mottrie, Alex

    Minerva urology and nephrology

    2023  Volume 75, Issue 2, Page(s) 223–230

    Abstract: Background: Patients with multiple ipsilateral renal masses have an augmented risk of metachronous contralateral lesions and are likely to undergo repeated surgeries. We report our experience with the technologies currently available and the surgical ... ...

    Abstract Background: Patients with multiple ipsilateral renal masses have an augmented risk of metachronous contralateral lesions and are likely to undergo repeated surgeries. We report our experience with the technologies currently available and the surgical techniques to preserve healthy parenchyma while guaranteeing oncological radicality during robot-assisted partial nephrectomy (RAPN).
    Methods: The data were collected at three tertiary-care centers, where 61 patients with multiple ipsilateral renal masses were treated with RAPN between 2012 and 2021. RAPN was performed with da Vinci Si or Xi surgical system using TilePro (Life360; San Francisco, CA, USA), indocyanine green fluorescence and intraoperative ultrasound. Three-dimensional reconstructions were built in some cases preoperatively. Different techniques were employed for hilum management. The primary endpoint is to report intra- and postoperative complications. Secondary endpoints were the estimated blood loss (EBL), warm ischemia time (WIT) and positive surgical margins (PSM) rate.
    Results: Median preoperative size of the largest mass was 37.5 mm (24-51) with a median PADUA and R.E.N.A.L. score of 8 (7-9) and 7 (6-9). One hundred forty-two tumors were excised, with a mean number of 2.32. The median WIT was 17 (12-24) minutes, and the median EBL was 200 (100-400) mL. Intraoperative ultrasound was employed in 40 (67.8%) patients. The rate of early unclamping, selective clamping and zero-ischemia were respectively 13 (21.3%), 6 (9.8%) and 13 (21.3%). ICG fluorescence was employed in 21 (34.42%) patients and three-dimensional reconstructions were built in 7 (11.47%) patients. Three (4.8%) intraoperative complications occurred, all classified as grade-1 according to EAUiaiC. Postoperative complications were reported in 14 (22.9%) cases with 2 Clavien-Dindo grade >2 complications. Four (6.56%) patients had PSM. Mean period of follow-up was 21 months.
    Conclusions: In experienced hands, with the employment of the currently available technologies and surgical techniques, RAPN can guarantee optimal outcomes in patients with multiple ipsilateral renal masses.
    MeSH term(s) Humans ; Robotics/methods ; Kidney Neoplasms/diagnostic imaging ; Kidney Neoplasms/surgery ; Kidney Neoplasms/pathology ; Treatment Outcome ; Nephrectomy/methods ; Postoperative Complications/etiology
    Language English
    Publishing date 2023-02-27
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 3062840-4
    ISSN 2724-6442
    ISSN (online) 2724-6442
    DOI 10.23736/S2724-6051.23.05161-3
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  8. Article: Robot-assisted adrenalectomy: Step-by-step technique and surgical outcomes at a high-volume robotic center.

    Piramide, Federico / Bravi, Carlo Andrea / Paciotti, Marco / Sarchi, Luca / Nocera, Luigi / Piro, Adele / Lores, Maria Peraire / Balestrazzi, Eleonora / Mottaran, Angelo / Farinha, Rui / Nicolas, Hubert / De Backer, Pieter / D'hondt, Frederiek / Schatteman, Peter / De Groote, Ruben / De Naeyer, Geert / Mottrie, Alexandre

    Asian journal of urology

    2023  Volume 10, Issue 4, Page(s) 475–481

    Abstract: Objective: In the last years, robotic surgery was introduced in several different settings with good perioperative results. However, its role in the management of adrenal masses is still debated. In order to provide a contribution to this field, we ... ...

    Abstract Objective: In the last years, robotic surgery was introduced in several different settings with good perioperative results. However, its role in the management of adrenal masses is still debated. In order to provide a contribution to this field, we described our step-by-step technique for robotic adrenalectomy (RA) and related modifications according to the type of adrenal mass treated.
    Methods: We retrospectively analyzed 27 consecutive patients who underwent RA at Onze-Lieve-Vrouw hospital (Aalst, Belgium) between January 2009 and October 2022. Demographic, intra- and post-operative, and pathological data were retrieved from our prospectively maintained institutional database. Continuous variables are summarized as median and interquartile range (IQR). Categorical variables are reported as frequencies (percentages).
    Results: Twenty-seven patients underwent RA were included in the study. Median age, body mass index, and Charlson's comorbidity index were 61 (IQR: 49-71) years, 26 (IQR: 24-29) kg/m
    Conclusion: We described our step-by-step technique for RA, which can be safely performed even in case of high challenging settings as malignant tumors, pheochromocytoma, and large masses. The standardization of perioperative protocol should be encouraged to maximize the outcomes of this complex surgical procedure.
    Language English
    Publishing date 2023-06-15
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 2831144-9
    ISSN 2214-3882
    ISSN 2214-3882
    DOI 10.1016/j.ajur.2023.04.001
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  9. Article ; Online: Different approaches for bladder neck dissection during robot-assisted radical prostatectomy: the Aalst technique.

    Bravi, Carlo A / Mottaran, Angelo / Sarchi, Luca / Piro, Adele / Paciotti, Marco / Nocera, Luigi / Balestrazzi, Eleonora / Peraire, Maria / Farinha, Rui / Pauwaert, Kim / Van Herwaarden, Manoe / Vinckier, Marie-Hélène / De Backer, Pieter / D'Hondt, Frederiek / De Groote, Ruben / De Naeyer, Geert / Mottrie, Alexandre

    International braz j urol : official journal of the Brazilian Society of Urology

    2023  Volume 49, Issue 4, Page(s) 521–522

    Abstract: Introduction: Bladder neck dissection is one of the most delicate surgical steps of robotic-assisted radical prostatectomy (RARP) [1, 2], and it may affect surgical margins rate and functional outcomes [3, 4]. Given the relationship between outcomes and ...

    Abstract Introduction: Bladder neck dissection is one of the most delicate surgical steps of robotic-assisted radical prostatectomy (RARP) [1, 2], and it may affect surgical margins rate and functional outcomes [3, 4]. Given the relationship between outcomes and surgical experience [5-7], it is crucial to implement a step-by-step approach for each surgical step of the procedure, especially in the most challenging part of the intervention. In this video compilation, we described the techniques for bladder neck dissection utilized at OLV Hospital (Aalst, Belgium).
    Surgical technique: We illustrated five different techniques for bladder neck dissection during RARP. The anterior technique tackles the bladder neck from above until the urethral catheter is visualized, and then the dissection is completed posteriorly. The lateral and postero-lateral approaches involve the identification of a weakness point at the prostate-vesical junction and aim to develop the posterior plane - virtually until the seminal vesicles - prior to the opening of the urethra anteriorly. Finally, we described our techniques for bladder neck dissection in more challenging cases such as in patients with bulky middle lobes and prior surgery for benign prostatic hyperplasia. All approaches follow anatomic landmarks to minimize positive surgical margins and aim to preserve the bladder neck in order to promote optimal functional recovery. All procedures were performed with DaVinci robotic platforms using a 3-instruments configuration (scissors, fenestrated bipolar, and needle driver). As standard protocol at our Institution, urinary catheter was removed on postoperative day two [8].
    Conclusions: Five different approaches for bladder neck dissection during RARP were described in this video compilation. We believe that the technical details provided here might be of help for clinicians who are starting their practice with this surgical intervention.
    MeSH term(s) Male ; Humans ; Urinary Bladder/surgery ; Robotic Surgical Procedures/methods ; Robotics/methods ; Neck Dissection ; Prostate ; Seminal Vesicles ; Prostatectomy/methods ; Prostatic Neoplasms/surgery
    Language English
    Publishing date 2023-05-31
    Publishing country Brazil
    Document type Video-Audio Media ; Journal Article
    ZDB-ID 2206649-4
    ISSN 1677-6119 ; 1677-5538
    ISSN (online) 1677-6119
    ISSN 1677-5538
    DOI 10.1590/S1677-5538.IBJU.2023.0027
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  10. Article ; Online: Transitioning from Da Vinci Si to Xi: assessing surgical outcomes at a high-volume robotic center.

    Bravi, Carlo A / Mottaran, Angelo / Sarchi, Luca / Piro, Adele / Paciotti, Marco / Nocera, Luigi / Piramide, Federico / Balestrazzi, Eleonora / Peraire, Maria / Farinha, Rui / Sorce, Gabriele / Collà-Ruvolo, Claudia / Rebuffo, Silvia / De Backer, Pieter / D'Hondt, Frederiek / De Groote, Ruben / De Naeyer, Geert / Mottrie, Alexandre

    World journal of urology

    2023  Volume 41, Issue 12, Page(s) 3737–3744

    Abstract: Purpose: In the emerging field of robotics, only few studies investigated the transition between different robotic platforms in terms of surgical outcomes. We aimed at assessing surgical outcomes of patients receiving robot-assisted radical ... ...

    Abstract Purpose: In the emerging field of robotics, only few studies investigated the transition between different robotic platforms in terms of surgical outcomes. We aimed at assessing surgical outcomes of patients receiving robot-assisted radical prostatectomy (RARP) and robot-assisted partial nephrectomy (RAPN) at a high-volume robotic center during the transition from Si to Xi Da Vinci surgical systems.
    Methods: We analyzed data of 1884 patients undergoing RARP (n = 1437, 76%) and RAPN (n = 447, 24%) at OLV hospital (Aalst, Belgium) between 2011 and 2021. For both procedures, we assessed operative time, estimated blood loss, length of stay, and positive surgical margins. For RARP, we investigated length of catheterization and PSA persistence after surgery, whereas warm ischemia time, clampless surgery, and acute kidney injury (AKI) were assessed for RAPN. Multivariable analyses (MVA) investigated the association between robotic platform (Si vs. Xi) and surgical outcomes after adjustment for patient- and tumor-related factors.
    Results: A total of 975 (68%) and 462 (32%) patients underwent RARP performed with the Si vs. Xi surgical system, respectively. Baseline characteristics did not differ between the groups. On MVA, we did not find evidence of a difference between the groups with respect to operative time (estimate: 1.07) or estimated blood loss (estimate: 32.39; both p > 0.05). Median (interquartile range [IQR]) length of stay was 6 (3, 6) and 4 (3, 5) days in the Si vs. Xi group, respectively (p < 0.0001). On MVA, men treated with the Xi vs. Si robot had lower odds of PSM (Odds ratio [OR]: 0.58; p = 0.014). A total of 184 (41%) and 263 (59%) patients received RAPN with the Si and Xi robotic system, respectively. Baseline characteristics, including demographics, functional data, and tumor-related features did not differ between the groups. On MVA, operative time was longer in the Xi vs. Si group (estimate: 30.54; p = 0.006). Patients treated with the Xi vs. Si system had higher probability of undergoing a clampless procedure (OR: 2.56; p = 0.001), whereas the risk of AKI did not differ between the groups (OR: 1.25; p = 0.4). On MVA, patients operated with the Xi robot had shorter length of stay as compared to the Si group (estimate: - 0.86; p = 0.003), whereas we did not find evidence of an association between robotic system and PSM (OR: 1.55; p = 0.3).
    Conclusion: We found that the Xi robot allowed for improvements in peri-operative outcomes as compared to the Si platform, with lower rate of positive margins for RARP and higher rate of off-clamp procedures for RAPN. Hospital stay was also shorter for patients operated with the Xi vs. Si robot, especially after robot-assisted partial nephrectomy. Awaiting future investigations-in particular, cost analyses-these results have important implications for patients, surgeons, and healthcare policymakers.
    MeSH term(s) Male ; Humans ; Robotics ; Treatment Outcome ; Robotic Surgical Procedures/methods ; Neoplasms ; Acute Kidney Injury
    Language English
    Publishing date 2023-11-02
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 380333-8
    ISSN 1433-8726 ; 0724-4983
    ISSN (online) 1433-8726
    ISSN 0724-4983
    DOI 10.1007/s00345-023-04665-9
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