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  1. AU="Mouna Esmaeilzadeh"
  2. AU=Congreve Miles
  3. AU="Li, Yunfeng" AU="Li, Yunfeng"
  4. AU="Shankar, Ganesh"
  5. AU="Ruginsk, Silvia G"
  6. AU="Aquilante, Francesco"
  7. AU="Dillon, Robert C"
  8. AU="Yuan Qu"
  9. AU="Dufour, A"
  10. AU="Hannus, Jill"
  11. AU="Rieber, Julia"
  12. AU="Gulmuradov, Tashpulat"
  13. AU="Romeu Fontanillas, Teresa"
  14. AU="Fleming, Renée"
  15. AU="Cao, Fang"
  16. AU="Sally J L Moore"
  17. AU="Moreno, Yolanda"
  18. AU="Vasiliy Ya. Kolyuchkin"

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  1. Artikel ; Online: Evaluation of a COVID-19 IgM and IgG rapid test; an efficient tool for assessment of past exposure to SARS-CoV-2

    Tove Hoffman / Karolina Nissen / Janina Krambrich / Bengt Rönnberg / Dario Akaberi / Mouna Esmaeilzadeh / Erik Salaneck / Johanna Lindahl / Åke Lundkvist

    Infection Ecology & Epidemiology, Vol 10, Iss

    2020  Band 1

    Abstract: COVID-19 is the most rapidly growing pandemic in modern time, and the need for serological testing is most urgent. Although the diagnostics of acute patients by RT-PCR is both efficient and specific, we are also crucially in need of serological tools for ...

    Abstract COVID-19 is the most rapidly growing pandemic in modern time, and the need for serological testing is most urgent. Although the diagnostics of acute patients by RT-PCR is both efficient and specific, we are also crucially in need of serological tools for investigating antibody responses and assessing individual and potential herd immunity. We evaluated a commercially available test developed for rapid (within 15 minutes) detection of SARS-CoV-2-specific IgM and IgG by 29 PCR-confirmed COVID-19 cases and 124 negative controls. The results revealed a sensitivity of 69% and 93.1% for IgM and IgG, respectively, based solely on PCR-positivity due to the absence of a serological gold standard. The assay specificities were shown to be 100% for IgM and 99.2% for IgG. This indicates that the test is suitable for assessing previous virus exposure, although negative results may be unreliable during the first weeks after infection. More detailed studies on antibody responses during and post infection are urgently needed.
    Schlagwörter covid-19 ; sars-cov-2 ; rapid test ; igm ; igg ; diagnostics ; Infectious and parasitic diseases ; RC109-216 ; covid19
    Sprache Englisch
    Erscheinungsdatum 2020-01-01T00:00:00Z
    Verlag Taylor & Francis Group
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Artikel ; Online: High seroprevalence of SARS-CoV-2 in elderly care employees in Sweden

    Johanna F. Lindahl / Tove Hoffman / Mouna Esmaeilzadeh / Björn Olsen / Reidar Winter / Stefan Amer / Christian Molnár / Ann Svalberg / Åke Lundkvist

    Infection Ecology & Epidemiology, Vol 10, Iss

    2020  Band 1

    Abstract: The COVID-19 pandemic is growing and spread in the Swedish elderly care system during April 2020. The increasing number of employees on sick-leave due to COVID-19 created severe logistic problems. Some elderly care homes therefore started to screen their ...

    Abstract The COVID-19 pandemic is growing and spread in the Swedish elderly care system during April 2020. The increasing number of employees on sick-leave due to COVID-19 created severe logistic problems. Some elderly care homes therefore started to screen their personnel to secure the safety of the elderly and to avoid unnecessary quarantine of potentially immune employees. Secondary data from a screening with a COVID-19 rapid test for detection of SARS-CoV-2-specific IgM and IgG of 1,005 employees in 22 elderly care homes in Stockholm, Sweden, were analyzed. Seropositive employees were found in 21 out of the 22 care homes. In total, 23% (231/1,005) of the employees tested positive for antibodies against SARS-CoV-2, and 14.3% (144/1,005) were found positive for IgM (either alone or combined with IgG), indicating recent or present infection. Of those that tested seropositive, 46.5% did not report any clinical symptoms, indicating pre- or asymptomatic infections. Reported symptoms with the highest correlation with seropositivity were fever and loss of smell and taste. These results suggest that antibody testing of employees in elderly care homes is valuable for surveillance of disease development and a crucial screening tool in the effort to decrease the death toll in this pandemic.
    Schlagwörter covid-19 ; sars-cov-2 ; rapid test ; igm ; igg ; employees ; elderly care homes ; Infectious and parasitic diseases ; RC109-216 ; covid19
    Thema/Rubrik (Code) 650
    Sprache Englisch
    Erscheinungsdatum 2020-01-01T00:00:00Z
    Verlag Taylor & Francis Group
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

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    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

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