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Article ; Online: Brunner's gland hamartomas: Not always benign.

Shmais, Manar / Mousawi, Ahmad / Mourad, Fadi / Sharara, Ala I

Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology

2024  Volume 25, Issue 1, Page(s) 70–73

Abstract: Brunner's gland hamartoma (BGH) is a rare, benign tumor of the duodenum. It is mostly asymptomatic and usually found incidentally on routine esophagogastroduodenoscopy (EGD). However, some BGHs present with major complications including anemia, bleeding, ...

Abstract Brunner's gland hamartoma (BGH) is a rare, benign tumor of the duodenum. It is mostly asymptomatic and usually found incidentally on routine esophagogastroduodenoscopy (EGD). However, some BGHs present with major complications including anemia, bleeding, obstruction, or dysplasia, requiring management and resection of these lesions. Herein, we present two cases of large BGHs of the duodenum, one presenting as severe gastrointestinal bleeding and the other, noted on EGD for iron deficiency anemia, found to have high grade dysplasia. This literature review discusses the rare serious complications of BGH, including iron deficiency anemia, overt gastrointestinal bleeding, and malignant potential.
MeSH term(s) Humans ; Brunner Glands/pathology ; Duodenal Diseases/diagnosis ; Duodenal Diseases/surgery ; Duodenal Diseases/complications ; Anemia, Iron-Deficiency/diagnosis ; Anemia, Iron-Deficiency/etiology ; Hamartoma/diagnosis ; Hamartoma/surgery ; Gastrointestinal Hemorrhage/etiology
Language English
Publishing date 2024-01-30
Publishing country Egypt
Document type Review ; Case Reports
ZDB-ID 2502114-X
ISSN 2090-2387 ; 1687-1979
ISSN (online) 2090-2387
ISSN 1687-1979
DOI 10.1016/j.ajg.2023.12.003
Database MEDical Literature Analysis and Retrieval System OnLINE

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