Article ; Online: Α case of seronegative autoimmune encephalitis associated with human herpesvirus-7 (HHV-7).
2021 Volume 94, Issue 2, Page(s) 795–798
Abstract: In the last 10 years, an increased number of patients presenting with acute encephalitis is being observed, a finding that is attributed to autoimmune mechanisms. Despite the fact that autoantibodies usually target the neuronal cell surface or synaptic ... ...
Abstract | In the last 10 years, an increased number of patients presenting with acute encephalitis is being observed, a finding that is attributed to autoimmune mechanisms. Despite the fact that autoantibodies usually target the neuronal cell surface or synaptic proteins in the central nervous system (CNS), in many cases these remain undetectable, constituting a future diagnostic and therapeutic challenge. Human herpesvirus-7 (HHV-7) is proven to be a neurotropic virus, causing various neurological complications mostly in the adult population. We present the case of a 10-year-old girl, with confirmed active HHV-7 infection of the CNS, who developed acute seronegative autoimmune encephalitis. To our best knowledge, there is no literature concerning pediatric cases of autoimmune encephalitis following HHV-7 infection. |
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MeSH term(s) | Antibodies, Viral/blood ; Autoantibodies/cerebrospinal fluid ; Autoimmune Diseases of the Nervous System/cerebrospinal fluid ; Brain/pathology ; Child ; Encephalitis/cerebrospinal fluid ; Female ; Herpesvirus 7, Human ; Humans ; Magnetic Resonance Imaging ; Recurrence ; Roseolovirus Infections/cerebrospinal fluid |
Chemical Substances | Antibodies, Viral ; Autoantibodies |
Language | English |
Publishing date | 2021-10-27 |
Publishing country | United States |
Document type | Case Reports ; Journal Article |
ZDB-ID | 752392-0 |
ISSN | 1096-9071 ; 0146-6615 |
ISSN (online) | 1096-9071 |
ISSN | 0146-6615 |
DOI | 10.1002/jmv.27411 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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