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  1. Article: The prenatal assessment of fetal health.

    Parboosingh, J / Mousseau, J / Deacon, J

    Canadian family physician Medecin de famille canadien

    2011  Volume 25, Page(s) 725–730

    Abstract: This article reviews the objectives, indications and methods currently used to assess fetal health in pregnancies at risk of fetoplacental dysfunction. The graphic display of clinical data encourages the physician to recognize deviations from the norm ... ...

    Abstract This article reviews the objectives, indications and methods currently used to assess fetal health in pregnancies at risk of fetoplacental dysfunction. The graphic display of clinical data encourages the physician to recognize deviations from the norm and assists in the selection of patients for assessment by the more sophisticated tests of fetoplacental function.
    Language English
    Publishing date 2011-02-07
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 603565-6
    ISSN 0008-350X
    ISSN 0008-350X
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  2. Article: Home healthcare.

    Mousseau, J

    Infection control and hospital epidemiology

    1992  Volume 13, Issue 3, Page(s) 135–136

    MeSH term(s) Epidemiologic Methods ; Home Care Services ; Humans ; Infection Control/statistics & numerical data
    Language English
    Publishing date 1992-03
    Publishing country United States
    Document type Comment ; Comparative Study ; Letter
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0899-823X ; 0195-9417
    ISSN (online) 1559-6834
    ISSN 0899-823X ; 0195-9417
    DOI 10.1086/646492
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  3. Article: Review: evidence does not support the effectiveness of over the counter preparations for acute cough.

    Mousseau, Johanne

    Evidence-based nursing

    2002  Volume 5, Issue 3, Page(s) 78

    Language English
    Publishing date 2002-07-16
    Publishing country England
    Document type Comment ; Journal Article
    ZDB-ID 1425988-6
    ISSN 1367-6539
    ISSN 1367-6539
    DOI 10.1136/ebn.5.3.78
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  4. Article: The family, prison of love

    Mousseau, J

    Readings in adult psychology : contemporary perspectives / edited by Lawrence R. Allman, Dennis T. Jaffe.

    1982  

    Keywords families ; psychology ; interpersonal relationships
    Language English
    Size p. 209-215., ill.
    Publisher Harper & Row, c1982.
    Publishing place New York
    Document type Article
    Note MAPP Empty nest/launching families.
    ISBN 0060402342 ; 9780060402341
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: Assessing the impacts of total liquid ventilation on left ventricular diastolic function in a model of neonatal respiratory distress syndrome.

    Sage, Michaël / Nadeau, Mathieu / Forand-Choinière, Claudia / Mousseau, Julien / Vandamme, Jonathan / Berger, Claire / Tremblay-Roy, Jean-Sébastien / Tissier, Renaud / Micheau, Philippe / Fortin-Pellerin, Étienne

    PloS one

    2018  Volume 13, Issue 1, Page(s) e0191885

    Abstract: Background: Filling the lung with dense liquid perfluorocarbons during total liquid ventilation (TLV) might compress the myocardium, a plausible explanation for the instability occasionally reported with this technique. Our objective is to assess the ... ...

    Abstract Background: Filling the lung with dense liquid perfluorocarbons during total liquid ventilation (TLV) might compress the myocardium, a plausible explanation for the instability occasionally reported with this technique. Our objective is to assess the impacts of TLV on the cardiovascular system, particularly left ventricular diastolic function, in an ovine model of neonatal respiratory distress syndrome.
    Method: Eight newborns lambs, 3.0 ± 0.4 days (3.2 ± 0.3kg) were used in this crossover experimental study. Animals were intubated, anesthetized and paralyzed. Catheters were inserted in the femoral and pulmonary arteries. A high-fidelity pressure catheter was inserted into the left ventricle. Surfactant deficiency was induced by repeated lung lavages with normal saline. TLV was then conducted for 2 hours using a liquid ventilator prototype. Thoracic echocardiography and cardiac output assessment by thermodilution were performed before and during TLV.
    Results: Left ventricular end diastolic pressure (LVEDP) (9.3 ± 2.1 vs. 9.2 ± 2.4mmHg, p = 0.89) and dimension (1.90 ± 0.09 vs. 1.86 ± 0.12cm, p = 0.72), negative dP/dt (-2589 ± 691 vs. -3115 ± 866mmHg/s, p = 0.50) and cardiac output (436 ± 28 vs. 481 ± 59ml/kg/min, p = 0.26) were not affected by TLV initiation. Left ventricular relaxation time constant (tau) slightly increased from 21.5 ± 3.3 to 24.9 ± 3.7ms (p = 0.03). Mean arterial systemic (48 ± 6 vs. 53 ± 7mmHg, p = 0.38) and pulmonary pressures (31.3 ± 2.5 vs. 30.4 ± 2.3mmHg, p = 0.61) were stable. As expected, the inspiratory phase of liquid cycling exhibited a small but significant effect on most variables (i.e. central venous pressure +2.6 ± 0.5mmHg, p = 0.001; LVEDP +1.18 ± 0.12mmHg, p<0.001).
    Conclusions: TLV was well tolerated in our neonatal lamb model of severe respiratory distress syndrome and had limited impact on left ventricle diastolic function when compared to conventional mechanical ventilation.
    MeSH term(s) Animals ; Animals, Newborn ; Diastole ; Disease Models, Animal ; Fluorocarbons/pharmacokinetics ; Liquid Ventilation/methods ; Respiratory Distress Syndrome, Newborn/physiopathology ; Respiratory Distress Syndrome, Newborn/therapy ; Sheep ; Ventricular Function, Left
    Chemical Substances Fluorocarbons ; perflubron (Q1D0Q7R4D9)
    Language English
    Publishing date 2018
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0191885
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  6. Article: Sur les variations de fréquence de conversion au niveau de divers sites d'un même locus.

    Mousseau, J

    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles

    1966  Volume 262, Issue 11, Page(s) 1254–1257

    Title translation On the variations of conversion frequency at the level of different sites of the same locus.
    MeSH term(s) Ascomycota ; Chromosome Mapping ; Chromosomes ; In Vitro Techniques
    Language French
    Publishing date 1966-03-14
    Publishing country France
    Document type Journal Article
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  7. Article: Effets de rayonnements gamma appliques en fractionnant la dose sur les organes de Nicotiana tabacum et Nicotiana sylvestris

    Mousseau, J

    Acta horticulturae. Dec 1977, 78

    1977  

    Title translation Effects of gamma irradiation in split doses on the organs of tobacco and Nicotiana sylvestris.
    Keywords plant physiology ; plant biochemistry ; field crops
    Language French
    Size p. 103-107.
    Document type Article
    ISSN 0567-7572
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Optimal Control of Inspired Perfluorocarbon Temperature for Ultrafast Hypothermia Induction by Total Liquid Ventilation in Adult Patient Model.

    Nadeau, Mathieu / Sage, Michael / Kohlhauer, Matthias / Mousseau, Julien / Vandamme, Jonathan / Fortin-Pellerin, Etienne / Praud, Jean-Paul / Tissier, Renaud / Walti, Herve / Micheau, Philippe

    IEEE transactions on bio-medical engineering

    2017  

    Abstract: Objective: Recent preclinical studies have shown that therapeutic hypothermia induced in less than 30 min by total liquid ventilation (TLV) strongly improves the survival rate after cardiac arrest. When the lung is ventilated with a breathable ... ...

    Abstract Objective: Recent preclinical studies have shown that therapeutic hypothermia induced in less than 30 min by total liquid ventilation (TLV) strongly improves the survival rate after cardiac arrest. When the lung is ventilated with a breathable perfluorocarbon liquid, the inspired perfluorocarbon allows to control efficiently the cooling process of the organs. While TLV can rapidly cool animals, the cooling speed in humans remains unknown. The objective is to predict the efficiency and safety of ultrafast cooling by TLV in adult humans.
    Methods: It is based on a previously published thermal model of ovines in TLV and the design of a direct optimal controller to compute the inspired perfluorocarbon temperature profile. The experimental results in an adult sheep are presented. The thermal model of sheep is subsequently projected to a human model to simulate the optimal hypothermia induction and its sensitivity to physiological parameter uncertainties.
    Results: The results in the sheep showed that the computed inspired perfluorocarbon temperature command can avoid arterial temperature undershoot. The projection to humans revealed that mild hypothermia should be ultrafast (reached in fewer than 3 min ( - 72
    Conclusion: The projection to human model allows concluding that therapeutic hypothermia induction by TLV can be ultrafast and safe.
    Significance: This study is the first to simulate ultrafast cooling by TLV in a human model and is a strong motivation to translate TLV to humans to improve the quality of life of post-cardiac arrest patients.
    Language English
    Publishing date 2017-02-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 160429-6
    ISSN 1558-2531 ; 0018-9294
    ISSN (online) 1558-2531
    ISSN 0018-9294
    DOI 10.1109/TBME.2017.2671741
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  9. Article: Introducing quality management in the community: the VON experience.

    Green, E / Hobbs, L / Mousseau, J

    Canadian journal of nursing administration

    1994  Volume 7, Issue 1, Page(s) 62–75

    Abstract: How does a national, non-profit, community health organization introduce and implement quality management (QM) throughout its branches? This article traces VON's move from a traditional quality assurance model to a systematic QM approach, focused on ... ...

    Abstract How does a national, non-profit, community health organization introduce and implement quality management (QM) throughout its branches? This article traces VON's move from a traditional quality assurance model to a systematic QM approach, focused on customers and on outcomes. Implementing Quality Management in a three-tiered organization (national, provincial and local levels), with boards and staff, is not an easy challenge but is feasible. Effective and creative strategic planning is a necessity. Educational strategies and ideas for implementation are included.
    MeSH term(s) Community Health Nursing ; Humans ; Total Quality Management ; Victoria
    Language English
    Publishing date 1994-01
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 1172132-7
    ISSN 0838-2948
    ISSN 0838-2948
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    Zs.A 3860: Show issues Location:
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  10. Article ; Online: Liquid ventilator for ultrafast hypothermia induction in juvenile lambs: Preliminary results.

    Nadeau, Mathieu / Sage, Michaël / Kohlhauer, Matthias / Robert, Raymond / Vandamne, Jonathan / Mousseau, Julien / Tissier, Renaud / Praud, Jean-Paul / Walti, Hervé / Micheau, Philippe

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

    2016  Volume 2015, Page(s) 1695–1698

    Abstract: Total liquid ventilation (TLV) is an emerging mechanical ventilation technique. In this technique, the lungs are filled with liquid perfluorocarbons (PFC) and a liquid ventilator assures ventilation by periodically renewing a volume of oxygenated, CO2 ... ...

    Abstract Total liquid ventilation (TLV) is an emerging mechanical ventilation technique. In this technique, the lungs are filled with liquid perfluorocarbons (PFC) and a liquid ventilator assures ventilation by periodically renewing a volume of oxygenated, CO2 freed and temperature controlled PFC. A huge difference between conventional mechanical ventilation and TLV relates to the fact that PFCs are about 1500 times denser than air. Thus, the PFCs filled lungs turn into an efficient heat exchanger with the circulating blood. One of the most appealing utilization of the lungs as a heat exchanger in TLV is for ultrafast induction of mild therapeutic hypothermia (MTH) for neuroprotection and cardioprotection after ischemia-reperfusion injuries. This study aimed to perform ultrafast MTH induction by TLV in animals up to 25 kg, then perform a fast post-hypothermic rewarming while maintaining proper ventilation. A thermal model of the lamb and liquid ventilator was developed to predict the dynamic and the control strategy to adopt for MTH induction. Two juvenile lambs were instrumented with temperature sensors in the femoral artery, pulmonary artery, oesophagus, right eardrum and rectum. After stabilization in conventional mechanical ventilation, TLV was initiated with ultrafast MTH induction, followed by posthypothermic rewarming. Preliminary results in the two juvenile lambs reveal that the liquid ventilator Inolivent-6.0 can induce MTH by TLV in less than 2.5 min for systemic arterial blood and in less than 10 min for venous return, esophagus and eardrum. Rectal temperature reached MTH in respectively 19.4 and 17.0 min for both lambs. Experimental results were consistent with the model predictions. Moreover, blood gas analysis exhibited that the gas exchange in the lungs was maintained adequately for the entire experiments.
    MeSH term(s) Animals ; Body Temperature ; Fluorocarbons ; Hypothermia, Induced/instrumentation ; Hypothermia, Induced/methods ; Liquid Ventilation ; Male ; Monitoring, Physiologic ; Respiration, Artificial/instrumentation ; Respiration, Artificial/methods ; Sheep, Domestic ; Ventilators, Mechanical
    Chemical Substances Fluorocarbons
    Language English
    Publishing date 2016-01-12
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2694-0604
    ISSN (online) 2694-0604
    DOI 10.1109/EMBC.2015.7318703
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