LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 85

Search options

  1. Book: Elementary Bayesian biostatistics

    Moyé, Lemuel A.

    (Chapman & Hall CRC biostatistics series ; 21)

    2008  

    Author's details Lemuel A. Moyé
    Series title Chapman & Hall CRC biostatistics series ; 21
    Chapman & Hall, CRC biostatistics series
    Collection Chapman & Hall, CRC biostatistics series
    Keywords Biometry / methods ; Bayes Theorem
    Language English
    Size XXI, 377 S. : graph. Darst.
    Publisher Chapman & Hall/CRC
    Publishing place Boca Raton u.a.
    Publishing country United States
    Document type Book
    Accompanying material 1 CD-ROM (12cm)
    HBZ-ID HT015537337
    ISBN 978-1-58488-724-9 ; 1-58488-724-9
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2007 MO 1118 <<[Begleitmaterial]>> order for loan Magazin
    2008 A 3211 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Book: Multiple analyses in clinical trials

    Moyé, Lemuel A.

    fundamentals for investigators

    (Statistics for biology and health)

    2003  

    Author's details Lemuel A. Moyé
    Series title Statistics for biology and health
    Keywords Research Design ; Multivariate Analysis ; Clinical Trials / methods ; Klinisches Experiment ; Multivariate Analyse
    Subject Mehrdimensionale Analyse ; Mehrvariablenanalyse ; Multivariate Statistik ; Multivariates Verfahren ; Therapiestudie ; Klinische Studie ; Klinischer Versuch ; Klinische Forschung
    Language English
    Size XXIII, 436 S. : graph. Darst.
    Publisher Springer
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT013825188
    ISBN 0-387-00727-X ; 978-0-387-00727-4
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2004 A 1153 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: Applications of Covariate Adjusted Nonparametric Methods to CCTRN Clinical Trials.

    Ye, Jiabu / Lai, Dejian / Moye, Lemuel A / Davis, Barry R

    Communications in statistics. Case studies, data analysis and applications

    2022  Volume 8, Issue 4, Page(s) 728–737

    Abstract: CCTRN is a Cardiovascular Cell Therapy Research Network. There were three randomized double blinded controlled stem cell clinical trials conducted in its first phase. The main results of these three clinical trials were published with conventional ... ...

    Abstract CCTRN is a Cardiovascular Cell Therapy Research Network. There were three randomized double blinded controlled stem cell clinical trials conducted in its first phase. The main results of these three clinical trials were published with conventional parametric models such as T test and nonparametric test such as Wilcoxon rank sum test without adjusting covariates. In this article, we conducted further analysis of the primary outcomes of these studies using a class of covariate adjusted nonparametric methods.
    Language English
    Publishing date 2022-09-22
    Publishing country United States
    Document type Journal Article
    ISSN 2373-7484
    ISSN 2373-7484
    DOI 10.1080/23737484.2022.2126414
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Book: Statistical reasoning in medicine

    Moyé, Lemuel A.

    the intuitive P-value primer

    2000  

    Author's details Lemuel A. Moyé
    Keywords Medizinische Statistik ; p-Wert
    Subject p-value
    Language English
    Size XXI, 281 S. : graph. Darst.
    Publisher Springer
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT012885844
    ISBN 0-387-98933-1 ; 978-0-387-98933-4
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2001 A 596 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Rudiments of subgroup analyses.

    Moyé, Lemuel A

    Progress in cardiovascular diseases

    2012  Volume 54, Issue 4, Page(s) 338–342

    Abstract: Subgroup analysis in a clinical trial is the evaluation of the effect of a randomly allocated intervention within only a fraction of the patients in the entire research cohort. This article provides several examples of the use of subgroup analysis, ... ...

    Abstract Subgroup analysis in a clinical trial is the evaluation of the effect of a randomly allocated intervention within only a fraction of the patients in the entire research cohort. This article provides several examples of the use of subgroup analysis, discusses some of the interpretative difficulties that occur during the assessment of the effect of therapy within subgroups, and provides a summary of recent recommendations on reporting subgroup analyses in the literature. Although subgroup analyses can provide new, provocative, and sometimes clinically relevant findings, this group of evaluations must be handled with extreme care.
    MeSH term(s) Cardiovascular Diseases/therapy ; Cohort Studies ; Data Interpretation, Statistical ; Humans ; Practice Guidelines as Topic ; Prospective Studies ; Randomized Controlled Trials as Topic/standards ; Research Design/standards ; Sample Size
    Language English
    Publishing date 2012-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209312-1
    ISSN 1873-1740 ; 1532-8643 ; 0033-0620
    ISSN (online) 1873-1740 ; 1532-8643
    ISSN 0033-0620
    DOI 10.1016/j.pcad.2011.07.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 229: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Book: Difference equations with public health applications

    Moyé, Lemuel A. / Kapadia, Asha Seth

    (Biostatistics ; 6)

    2000  

    Author's details Lemuel A. Moyé ; Asha Seth Kapadia
    Series title Biostatistics ; 6
    Collection
    Language English
    Size XIV, 392 S. : graph. Darst.
    Publisher Dekker
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT012869734
    ISBN 0-8247-0447-9 ; 978-0-8247-0447-6
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2000 A 5311 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article: Disciplined analyses in clinical trials: the dark heart of the matter.

    Moyé, Lemuel A

    Statistical methods in medical research

    2008  Volume 17, Issue 3, Page(s) 253–264

    Abstract: Clinical research analyses must balance the desire to ;learn all that is learnable' from the database with the observation that sample-based data commonly lead to conclusions that are perfectly correct for the sample, but wholly incorrect for the ... ...

    Abstract Clinical research analyses must balance the desire to ;learn all that is learnable' from the database with the observation that sample-based data commonly lead to conclusions that are perfectly correct for the sample, but wholly incorrect for the population from which the data were based. Investigators who defend exploratory analyses as reliable, misuse important tools that have taken over three hundred years to develop. Statistical estimators in clinical trials function appropriately when they incorporate random data that is gathered in response to a fixed research question. Their prediction ability degrades rapidly when the selection of the research question is itself random, that is, left to the data. Operating like blind guides, these estimators mislead the medical community about what it would see in the population, based on sample observations. The result is a wavering research focus, leaping from one provocative but misleading finding to the next on the powerful waves of sampling error. Therefore, a primary purpose of the prospective design is to fix the research questions prospectively, thereby anchoring the analysis plan. Prospective statements of the research questions and rejection of tempting databased changes to the protocol preserve the best estimates of effect sizes, standard errors, confidence intervals and p-values. Embracing these principles promotes the prosecution of a successful research program, that is, the construction and protection of a research environment that permits an objective assessment of the therapy or exposure being studied. If there is any fixed star in the research constellation, it is that sample-based research must be hypothesis-driven and concordantly executed to have real meaning for both the scientific community and the patient populations that we serve.
    MeSH term(s) Controlled Clinical Trials as Topic/economics ; Controlled Clinical Trials as Topic/standards ; Controlled Clinical Trials as Topic/statistics & numerical data ; Controlled Clinical Trials as Topic/trends ; Humans ; Prospective Studies ; Research Design/standards ; Research Design/statistics & numerical data ; Research Design/trends ; Sample Size ; United States
    Language English
    Publishing date 2008-06
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1136948-6
    ISSN 1477-0334 ; 0962-2802
    ISSN (online) 1477-0334
    ISSN 0962-2802
    DOI 10.1177/0962280207080641
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 3564: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article: Bayesians in clinical trials: asleep at the switch.

    Moyé, Lemuel A

    Statistics in medicine

    2008  Volume 27, Issue 4, Page(s) 469–82; discussion 483–9

    Abstract: The refreshing Bayes perspective has much to offer biostatistics. Yet, from its 225-year-old roots sprung difficulties that blocked its growth at the beginning of the 20th century. Computational obstacles in concert with an inability to identify the best ...

    Abstract The refreshing Bayes perspective has much to offer biostatistics. Yet, from its 225-year-old roots sprung difficulties that blocked its growth at the beginning of the 20th century. Computational obstacles in concert with an inability to identify the best indifferent prior revealed a weakness on which frequentists capitalized. It took Bayesians 40 years to recover, allowing the infant field of biostatistics to fall firmly in the hands of the frequentists. Recent disillusionment with the frequentist perspective, and its hegemony of p-values, has produced a second opportunity for the Bayesian philosophy to make solid contributions to clinical trials.However, difficulty with the applicability of the likelihood principle, problems with prevalent prior 'disinformation' in clinical medicine, in concert with the complexity of truly representative loss functions threaten again to thwart the Bayesian march into biostatistics. Seven suggestions are offered to the Bayesians to help them adapt to the rigors of clinical research.
    MeSH term(s) Bayes Theorem ; Biometry/methods ; Clinical Trials as Topic/statistics & numerical data ; Reproducibility of Results
    Language English
    Publishing date 2008-02-20
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 843037-8
    ISSN 1097-0258 ; 0277-6715
    ISSN (online) 1097-0258
    ISSN 0277-6715
    DOI 10.1002/sim.2928
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1756: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Meta-Analyses of Human Cell-Based Cardiac Regeneration Therapies: Controversies in Meta-Analyses Results on Cardiac Cell-Based Regenerative Studies.

    Gyöngyösi, Mariann / Wojakowski, Wojciech / Navarese, Eliano P / Moye, Lemuel À

    Circulation research

    2016  Volume 118, Issue 8, Page(s) 1254–1263

    Abstract: In contrast to multiple publication-based meta-analyses involving clinical cardiac regeneration therapy in patients with recent myocardial infarction, a recently published meta-analysis based on individual patient data reported no effect of cell therapy ... ...

    Abstract In contrast to multiple publication-based meta-analyses involving clinical cardiac regeneration therapy in patients with recent myocardial infarction, a recently published meta-analysis based on individual patient data reported no effect of cell therapy on left ventricular function or clinical outcome. A comprehensive review of the data collection, statistics, and the overall principles of meta-analyses provides further clarification and explanation for this controversy. The advantages and pitfalls of different types of meta-analyses are reviewed here. Each meta-analysis approach has a place when pivotal clinical trials are lacking and sheds light on the magnitude of the treatment in a complex healthcare field.
    MeSH term(s) Cell- and Tissue-Based Therapy/methods ; Cell- and Tissue-Based Therapy/mortality ; Cell- and Tissue-Based Therapy/trends ; Humans ; Mortality/trends ; Myocardial Ischemia/mortality ; Myocardial Ischemia/therapy ; Randomized Controlled Trials as Topic/methods ; Regeneration/physiology ; Stem Cell Transplantation/methods ; Stem Cell Transplantation/mortality ; Stem Cell Transplantation/trends ; Ventricular Function, Left/physiology
    Language English
    Publishing date 2016-04-15
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 80100-8
    ISSN 1524-4571 ; 0009-7330 ; 0931-6876
    ISSN (online) 1524-4571
    ISSN 0009-7330 ; 0931-6876
    DOI 10.1161/CIRCRESAHA.115.307347
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ui IV Zs.70: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Ui IV Zs.60: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Book: Elementary Bayesian biostatistics

    Moyé, Lemuel A

    (Chapman & Hall/CRC biostatistics series ; 21)

    2008  

    Author's details Lemuel A. Moyé
    Series title Chapman & Hall/CRC biostatistics series ; 21
    MeSH term(s) Biometry/methods ; Bayes Theorem
    Language English
    Size xxi, 377 p. :, ill., port. +
    Publisher Chapman & Hall/CRC
    Publishing place Boca Raton
    Document type Book
    Accompanying material 1 CD-ROM (4 3/4 in.).
    ISBN 9781584887249 ; 1584887249
    Database Catalogue of the US National Library of Medicine (NLM)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top