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Artikel ; Online: Insight into the Molecular Mechanism of Diabetic Kidney Disease and the Role of Metformin in Its Pathogenesis.

Kleibert, Marcin / Zygmunciak, Przemysław / Łakomska, Klaudia / Mila, Klaudia / Zgliczyński, Wojciech / Mrozikiewicz-Rakowska, Beata

International journal of molecular sciences

2023 Band 24, Heft 17

Abstract: Diabetic kidney disease (DKD) is one of the leading causes of death among patients diagnosed with diabetes mellitus. Despite the growing knowledge about the pathogenesis of DKD, we still do not have effective direct pharmacotherapy. Accurate blood sugar ... ...

Abstract	Diabetic kidney disease (DKD) is one of the leading causes of death among patients diagnosed with diabetes mellitus. Despite the growing knowledge about the pathogenesis of DKD, we still do not have effective direct pharmacotherapy. Accurate blood sugar control is essential in slowing down DKD. It seems that metformin has a positive impact on kidneys and this effect is not only mediated by its hypoglycemic action, but also by direct molecular regulation of pathways involved in DKD. The molecular mechanism of DKD is complex and we can distinguish polyol, hexosamine, PKC, and AGE pathways which play key roles in the development and progression of this disease. Each of these pathways is overactivated in a hyperglycemic environment and it seems that most of them may be regulated by metformin. In this article, we summarize the knowledge about DKD pathogenesis and the potential mechanism of the nephroprotective effect of metformin. Additionally, we describe the impact of metformin on glomerular endothelial cells and podocytes, which are harmed in DKD.
Mesh-Begriff(e)	Humans ; Diabetic Nephropathies/drug therapy ; Diabetic Nephropathies/etiology ; Metformin/pharmacology ; Metformin/therapeutic use ; Endothelial Cells ; Kidney ; Hypoglycemic Agents/pharmacology ; Hypoglycemic Agents/therapeutic use ; Diabetes Mellitus/drug therapy
Chemische Substanzen	Metformin (9100L32L2N) ; Hypoglycemic Agents
Sprache	Englisch
Erscheinungsdatum	2023-08-22
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article ; Review
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms241713038
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: The Problem of Wound Healing in Diabetes-From Molecular Pathways to the Design of an Animal Model.

Mieczkowski, Mateusz / Mrozikiewicz-Rakowska, Beata / Kowara, Michał / Kleibert, Marcin / Czupryniak, Leszek

International journal of molecular sciences

2022 Band 23, Heft 14

Abstract: Chronic wounds are becoming an increasingly common clinical problem due to an aging population and an increased incidence of diabetes, atherosclerosis, and venous insufficiency, which are the conditions that impair and delay the healing process. Patients ...

Abstract	Chronic wounds are becoming an increasingly common clinical problem due to an aging population and an increased incidence of diabetes, atherosclerosis, and venous insufficiency, which are the conditions that impair and delay the healing process. Patients with diabetes constitute a group of subjects in whom the healing process is particularly prolonged regardless of its initial etiology. Circulatory dysfunction, both at the microvascular and macrovascular levels, is a leading factor in delaying or precluding wound healing in diabetes. The prolonged period of wound healing increases the risk of complications such as the development of infection, including sepsis and even amputation. Currently, many substances applied topically or systemically are supposed to accelerate the process of wound regeneration and finally wound closure. The role of clinical trials and preclinical studies, including research based on animal models, is to create safe medicinal products and ensure the fastest possible healing. To achieve this goal and minimize the wide-ranging burdens associated with conducting clinical trials, a correct animal model is needed to replicate the wound conditions in patients with diabetes as closely as possible. The aim of the paper is to summarize the most important molecular pathways which are impaired in the hyperglycemic state in the context of designing an animal model of diabetic chronic wounds. The authors focus on research optimization, including economic aspects and model reproducibility, as well as the ethical dimension of minimizing the suffering of research subjects according to the 3 Rs principle (Replacement, Reduction, Refinement).
Mesh-Begriff(e)	Amputation ; Animals ; Diabetes Mellitus ; Diabetic Foot/drug therapy ; Disease Models, Animal ; Humans ; Reproducibility of Results ; Wound Healing
Sprache	Englisch
Erscheinungsdatum	2022-07-19
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article ; Review
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms23147930
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Czy autoimmunizacja tarczycy jest związana z subkliniczną miażdżycą u młodych kobiet z cukrzycą typu 1?

Łukawska-Tatarczuk, Magdalena Maria / Zieliński, Jakub / Franek, Edward / Czupryniak, Leszek / Mrozikiewicz-Rakowska, Beata

Endokrynologia Polska

2022 Band 73, Heft 2, Seite(n) 301–308

Abstract: Introduction: It has been hypothesized that autoimmunity may contribute to cardiovascular complications and may be an important trigger for processes leading to atherosclerosis, especially in type 1 diabetes mellitus (T1DM). This pilot study aimed to ... ...

Titelübersetzung	Is thyroid autoimmunity associated with subclinical atherosclerosis in young women with type 1 diabetes mellitus?
Abstract	Introduction: It has been hypothesized that autoimmunity may contribute to cardiovascular complications and may be an important trigger for processes leading to atherosclerosis, especially in type 1 diabetes mellitus (T1DM). This pilot study aimed to answer the question of whether markers of thyroid autoimmunity are associated with increased carotid intima-media thickness (cIMT) in young, asymptomatic T1DM women. Material and methods: The study population consisted of 102 women, including 72 with T1DM and 30 healthy controls. All patients had thyroid hormones within the normal range. According to the antiperoxidase antibodies (aTPO) titre, the T1DM women were divided into an aTPO-positive (T1DM aTPO+) (n = 41) and an aTPO-negative (T1DM aTPO-) (n = 31) group. In all patients, aTPO, thyroglobulin antibody (aTG) titres, thyroid-stimulating hormone (TSH), free thyroxine (FT3), free triiodothyronine (FT4), lipid parameters, glycated haemoglobin, thyroid ultrasonography, and cIMT assessment were evaluated. The association of cIMT with different risk factors related to thyroid autoimmunity was determined. Results: Carotid intima-media thickness was significantly greater in T1DM aTPO+ females (0.66 ± 0.10 mm) than in T1DM aTPO- (0.59 ± 0.11 mm) and healthy controls (0.58 ± 0.10 mm) (p = 0.007, p = 0.001, respectively). In all women cIMT was significantly, positively correlated with aTPO (p = 0.005, r = 0.273), Hashimoto's thyroiditis (HT) duration (p = 0.00015, r = 0.367), levothyroxine dose per week (p = 0.006, r = 0.269), and ultrasound features of HT (p = 0.004, r = 0.281) and inversely with fT3 concentration (p = 0.014, r = -0.243) and FT3/FT4 ratio (p = 0.042, r = -0.201). A logistic regression analysis showed that HT duration (OR: 1.102, 95% CI: 1.008-1.206, p = 0.032) and a positive history family of HT (OR: 3.909, 95%CI: 1.014-15.071, p = 0.045) were risk factors for increased cIMT. However, multivariate regression analysis showed that the studied parameters related to thyroid autoimmunity are not independent risk factors for increased cIMT. Conclusions: We expanded the data on cIMT in young women with T1DM and showed that thyroid autoimmunity, and in particular the duration of exposure to anti-thyroid antibodies, despite adequate levothyroxine substitution, is associated with subclinical atherosclerosis in young women with T1DM. However, thyroid-related parameters are not independent risk factors for increased cIMT in euthyroid women.
Mesh-Begriff(e)	Atherosclerosis/complications ; Autoimmunity ; Carotid Intima-Media Thickness ; Diabetes Mellitus, Type 1/complications ; Female ; Hashimoto Disease/complications ; Humans ; Pilot Projects ; Thyroid Hormones ; Thyroxine
Chemische Substanzen	Thyroid Hormones ; Thyroxine (Q51BO43MG4)
Sprache	Englisch
Erscheinungsdatum	2022-04-05
Erscheinungsland	Poland
Dokumenttyp	Journal Article
ZDB-ID	419270-9
ISSN	2299-8306 ; 0423-104X
ISSN (online)	2299-8306
ISSN	0423-104X
DOI	10.5603/EP.a2022.0018
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Breakdown of Diabetic Foot Ulcer Care during the First Year of the Pandemic in Poland: A Retrospective National Cohort Study.

Kleibert, Marcin / Mrozikiewicz-Rakowska, Beata / Bąk, Patrycja Małgorzata / Bałut, Daniel / Zieliński, Jakub / Czupryniak, Leszek

International journal of environmental research and public health

2022 Band 19, Heft 7

Abstract: The COVID-19 pandemic revealed a breakdown of the system of DFU patient care. This retrospective national cohort study analyses the epidemiological status of DFU patients in relation to urgent and elective hospitalizations, amputation rates, and deaths ... ...

Abstract	The COVID-19 pandemic revealed a breakdown of the system of DFU patient care. This retrospective national cohort study analyses the epidemiological status of DFU patients in relation to urgent and elective hospitalizations, amputation rates, and deaths in Poland from 2017 to 2019, and during 2020 when the COVID-19 pandemic began. The data were obtained from national medical records gathered by the National Health Fund (NHF). Discharge diagnoses were categorized according to ICD-10 and ICD-9 codes. Analysis of the data showed a statistically significant decrease in elective hospital admissions (from 29.6% to 26.3%,
Mesh-Begriff(e)	COVID-19/epidemiology ; Cohort Studies ; Diabetes Mellitus ; Diabetic Foot/epidemiology ; Diabetic Foot/therapy ; Humans ; Pandemics ; Poland/epidemiology ; Retrospective Studies
Sprache	Englisch
Erscheinungsdatum	2022-03-23
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph19073827
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: A new algorithm for the management of diabetic foot ulcer: recommendations from Central and Eastern Europe.

Bem, Robert / Chadwick, Paul / Cvjetko, Ivan / Koliba, Miroslav / Kokeny, Zoltan / Lipinski, Przemyslaw / Mrozikiewicz-Rakowska, Beata / Rozsos, Istvan / Wegrzynowski, Adam

Journal of wound care

2023 Band 32, Heft 5, Seite(n) 264–272

Abstract: There is wide regional variation in clinical practice and access to treatment for patients with diabetic foot ulcer (DFU) from countries in Central and Eastern Europe (CEE). A treatment algorithm that reflects current treatment practices while providing ... ...

Abstract	There is wide regional variation in clinical practice and access to treatment for patients with diabetic foot ulcer (DFU) from countries in Central and Eastern Europe (CEE). A treatment algorithm that reflects current treatment practices while providing a common framework may facilitate best practice in DFU management and improve outcomes across the CEE region. Following a series of regional advisory board meetings with experts from Poland, the Czech Republic, Hungary and Croatia, we present consensus recommendations for the management of DFU and outline the key features of a unified algorithm for dissemination and use as a quick tool in clinical practice in CEE. The algorithm should be accessible to specialists as well as non-specialist clinicians and should incorporate: patient screening; checkpoints for assessment and referral; triggers of treatment change; and strategies for infection control, wound bed preparation and offloading. Among adjunctive treatments in DFU, there is a clear role for topical oxygen therapy, which can be used concomitantly with most existing treatment regimens in hard-to-heal wounds following standard of care. Countries from CEE face a number of challenges in the management of DFU. It is hoped that such an algorithm will help standardise the approach to DFU management and overcome some of these challenges. Ultimately, a regionwide treatment algorithm in CEE has the potential to improve clinical outcomes and save limbs.
Mesh-Begriff(e)	Humans ; Diabetic Foot/therapy ; Europe ; Wound Healing ; Europe, Eastern ; Algorithms ; Diabetes Mellitus
Sprache	Englisch
Erscheinungsdatum	2023-03-16
Erscheinungsland	England
Dokumenttyp	Journal Article
ZDB-ID	1353951-6
ISSN	0969-0700
ISSN	0969-0700
DOI	10.12968/jowc.2023.32.5.264
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Związek przeciwciał przeciwko peroksydazie tarczycowej z funkcją serca u kobiet w stanie eutyreozy z cukrzycą typu 1 - ocena za pomocą dwuwymiarowej echokardiografii przy użyciu metody śledzenia markerów akustycznych.

Łukawska-Tatarczuk, Magdalena Maria / Pawlak, Agnieszka / Zieliński, Jakub / Franek, Edward / Czupryniak, Leszek / Mrozikiewicz-Rakowska, Beata

Endokrynologia Polska

2022 Band 73, Heft 5, Seite(n) 812–822

Abstract: Introduction: The presence of diabetes is associated with loss of cardioprotection in premenopausal women; however, the mechanisms involved remain unknown. Autoimmune factors are suspected to play a role in cardiovascular complications, especially in ... ...

Titelübersetzung	Association of antithyroid peroxidase antibodies with cardiac function in euthyroid women with type 1 diabetes mellitus - assessment with two-dimensional speckle‑tracking echocardiography.
Abstract	Introduction: The presence of diabetes is associated with loss of cardioprotection in premenopausal women; however, the mechanisms involved remain unknown. Autoimmune factors are suspected to play a role in cardiovascular complications, especially in type 1 diabetes (T1DM). The aim of this pilot study was to explore whether antithyroid peroxidase antibody (aTPO) as a marker of increased immune activity is related to cardiac dysfunction in young, asymptomatic women with T1DM. Material and methods: Eighty-eight euthyroid women (59 with T1DM and 29 healthy controls) underwent physical examination, laboratory tests, thyroid ultrasound, and two-dimensional speckle-tracking echocardiography. According to the antiperoxidase antibodies (aTPO) titre, the T1DM women were divided into an aTPO positive (T1DM aTPO+) (n = 34) and an aTPO negative (T1DM aTPO-) (n = 25) group. The relationship between thyroid autoimmunity parameters and echocardiographic parameters was evaluated. Results: Global longitudinal strain (GLS) was slightly reduced in the T1DM aTPO+ group compared to T1DM aTPO- and significantly compared to controls (p = 0.051 and p = 0.015, respectively). Although, the lower values of longitudinal strain of left ventricular were found in the majority of segments in the T1DM aTPO+ group in comparison to T1DM aTPO- and controls, significant differences were only found in the two-chamber view (specifically in the anterior segments) between the T1DM aTPO+ and T1DM aTPO- groups (p = 0.030) and in the four-chamber view (specifically in the anterolateral segments) between the T1DM aTPO+ group and controls (p = 0.021). Echocardiographic parameters of diastolic and systolic function of both ventricles were significantly correlated with parameters of thyroid autoimmunity. A logistic regression analysis showed that Hashimoto's thyroiditis (HT) duration [odds ratio (OR): 0.997, 95% confidence interval (CI): 0.995-0.999, p = 0.008), the dose of levothyroxine (OR: 0.814, 95% CI: 0.689-0.960, p = 0.013), and reduced echogenicity on thyroid ultrasound (OR: 0.309, 95% CI: 0.120-0.793, p = 0.013) had a significant influence on reduced GLS. Conclusions: Our results suggest that coexistence of aTPO with T1DM was associated with poorer myocardial function, particularly in the anterior and anterolateral segments, which may be related to an autoimmune factor. The impaired function of these segments is probably the first sign of myocardial systolic dysfunction in women with T1DM, which needs to be confirmed in further studies.
Mesh-Begriff(e)	Humans ; Female ; Diabetes Mellitus, Type 1/complications ; Pilot Projects ; Echocardiography/methods ; Hashimoto Disease/complications ; Heart Diseases/complications ; Peroxidases ; Ventricular Dysfunction, Left
Chemische Substanzen	Peroxidases (EC 1.11.1.-)
Sprache	Englisch
Erscheinungsdatum	2022-08-16
Erscheinungsland	Poland
Dokumenttyp	English Abstract ; Journal Article
ZDB-ID	419270-9
ISSN	2299-8306 ; 0423-104X
ISSN (online)	2299-8306
ISSN	0423-104X
DOI	10.5603/EP.a2022.0041
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: The Use of Glucocorticoids for Better Control of Diabetes Mellitus: The Paradox of Sclerosing Mesenteritis (The Rare Could Become Common).

Mrozikiewicz-Rakowska, Beata / Zygmunciak, Mateusz / Głażewski, Tomasz / Mieczkowski, Mateusz / Podgórska, Joanna / Rowiński, Olgierd / Czupryniak, Leszek

The American journal of case reports

2021 Band 22, Seite(n) e930453

Abstract: BACKGROUND Sclerosing mesenteritis is a rare disease characterized by chronic inflammation of mesenteric adipose tissue. To our knowledge, this is the first case report that presents the effects of glucocorticoid therapy on metabolic control in diabetes ... ...

Abstract	BACKGROUND Sclerosing mesenteritis is a rare disease characterized by chronic inflammation of mesenteric adipose tissue. To our knowledge, this is the first case report that presents the effects of glucocorticoid therapy on metabolic control in diabetes mellitus, aggravated by sclerosing mesenteritis. We want to show the significance of this rare disease, which could be underestimated as a cause of decompensation of diabetes mellitus. CASE REPORT A 57-year-old man with diabetes type 2 was admitted to the hospital to obtain better metabolic control of this disease. In addition, he reported persistent pain in the left side of his abdomen. Sclerosing mesenteritis was diagnosed based on the CT and MRI images. Prednisone was administered. The treatment resulted in better glycemic control and abdominal pain reduction. On follow-up after 1 year, the patient reported a decrease in the abdominal pain and an MRI showed a significant reduction of abnormalities in the mesentery. CONCLUSIONS It is known that glucocorticoids exacerbate hyperglycemia, particularly in patients with diabetes mellitus. However, we noticed contrary effects in the case of our patient. We suggest that the inflammatory process occurring in sclerosing mesenteritis was one of the main causes of metabolic decompensation in our patient. The effect of reduction of inflammation with glucocorticoids was stronger than the hyperglycemic effect of this treatment. That is why, in the presence of this autoimmune disease, the use of glucocorticoids can paradoxically lead to better glycemic control.
Mesh-Begriff(e)	Diabetes Mellitus ; Diagnosis, Differential ; Glucocorticoids/therapeutic use ; Humans ; Magnetic Resonance Imaging ; Male ; Mesentery ; Middle Aged ; Panniculitis, Peritoneal/drug therapy
Chemische Substanzen	Glucocorticoids
Sprache	Englisch
Erscheinungsdatum	2021-05-31
Erscheinungsland	United States
Dokumenttyp	Case Reports ; Journal Article
ZDB-ID	2517183-5
ISSN	1941-5923 ; 1941-5923
ISSN (online)	1941-5923
ISSN	1941-5923
DOI	10.12659/AJCR.930453
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Radionuclide imaging and therapy in a patient with coexistent diabetic foot syndrome and psoriatic arthritis.

Chojnowski, Marek Marcin / Mrozikiewicz-Rakowska, Beata / Kobylecka, Małgorzata / Czupryniak, Leszek / Królicki, Leszek

Nuclear medicine review. Central & Eastern Europe

2019 Band 20, Heft 2, Seite(n) 101–102

Abstract: We report a case of 67-year-old man suffering from psoriatic arthritis, type 2 diabetes and diabetic foot syndrome. The patient presented symptoms of inflammation of the right ankle joint. Scintigraphic imaging with radiolabeled white blood cells was ... ...

Abstract	We report a case of 67-year-old man suffering from psoriatic arthritis, type 2 diabetes and diabetic foot syndrome. The patient presented symptoms of inflammation of the right ankle joint. Scintigraphic imaging with radiolabeled white blood cells was performed to differentiate whether the inflammation was related to psoriatic arthritis or diabetic foot syndrome. After revealing that, the inflammatory process was restricted only to the articular space of subtalar joint, the patient was diagnosed with exacerbation of psoriatic arthritis and qualified for radionuclide synovectomy. In patients with coexistent diabetic foot syndrome and inflammatory arthritis of the foot it is of vital importance to accurately differentiate these two conditions. We conclude that this can be potentially achieved with radiolabeled white blood cells scintigraphic imaging.
Sprache	Englisch
Erscheinungsdatum	2019-03-21
Erscheinungsland	Poland
Dokumenttyp	Journal Article
ZDB-ID	1467537-7
ISSN	1644-4345 ; 1506-9680
ISSN (online)	1644-4345
ISSN	1506-9680
DOI	10.5603/NMR.2017.0016
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Allogenic Adipose-Derived Stem Cells in Diabetic Foot Ulcer Treatment: Clinical Effectiveness, Safety, Survival in the Wound Site, and Proteomic Impact.

Mrozikiewicz-Rakowska, Beata / Szabłowska-Gadomska, Ilona / Cysewski, Dominik / Rudziński, Stefan / Płoski, Rafał / Gasperowicz, Piotr / Konarzewska, Magdalena / Zieliński, Jakub / Mieczkowski, Mateusz / Sieńko, Damian / Grzela, Tomasz / Noszczyk, Maria / Paleska, Barbara / Czupryniak, Leszek / Lewandowska-Szumiel, Malgorzata

International journal of molecular sciences

2023 Band 24, Heft 2

Abstract: Although encouraging results of adipose-derived stem cell (ADSC) use in wound healing are available, the mechanism of action has been studied mainly in vitro and in animals. This work aimed to examine the safety and efficacy of allogenic ADSCs in human ... ...

Abstract	Although encouraging results of adipose-derived stem cell (ADSC) use in wound healing are available, the mechanism of action has been studied mainly in vitro and in animals. This work aimed to examine the safety and efficacy of allogenic ADSCs in human diabetic foot ulcer treatment, in combination with the analyses of the wound. Equal groups of 23 participants each received fibrin gel with ADSCs or fibrin gel alone. The clinical effects were assessed at four time points: days 7, 14, 21 and 49. Material collected during debridement from a subset of each group was analyzed for the presence of ADSC donor DNA and proteomic changes. The reduction in wound size was greater at all subsequent visits, significantly on day 21 and 49, and the time to 50% reduction in the wound size was significantly shorter in patients who received ADSCs. Complete healing was achieved at the end of the study in seven patients treated with ADSCs vs. one treated without ADSCs. One week after ADSC application, 34 proteins significantly differentiated the material from both groups, seven of which, i.e., GAPDH, CAT, ACTN1, KRT1, KRT9, SCL4A1, and TPI, positively correlated with the healing rate. We detected ADSC donor DNA up to 21 days after administration. We confirmed ADSC-related improvement in wound healing that correlated with the molecular background, which provides insights into the role of ADSCs in wound healing-a step toward the development of cell-based therapies.
Mesh-Begriff(e)	Animals ; Humans ; Diabetic Foot/therapy ; Diabetic Foot/metabolism ; Proteomics ; Stem Cells ; Adipocytes ; Treatment Outcome ; Adipose Tissue/metabolism ; Diabetes Mellitus/metabolism
Sprache	Englisch
Erscheinungsdatum	2023-01-12
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms24021472
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Embedding Wound Hygiene into a proactive wound healing strategy.

Murphy, Chris / Atkin, Leanne / Vega de Ceniga, Melina / Weir, Dot / Swanson, Terry / Walker, Angela / Mrozikiewicz-Rakowska, Beata / Ciprandi, Guido / Lázaro-Martínez, José Luis / Černohorská, Júlia

Journal of wound care

2022 Band 31, Heft Sup4a, Seite(n) S1–S19

Abstract: Foreword. wound hygiene: the next stage: Since a panel published the first consensus document on Wound Hygiene in March 2020, there has been a flurry of activity in support of this newly established concept in proactive wound healing. ...

Abstract	Foreword. wound hygiene: the next stage: Since a panel published the first consensus document on Wound Hygiene in March 2020, there has been a flurry of activity in support of this newly established concept in proactive wound healing.
Mesh-Begriff(e)	Consensus ; Humans ; Hygiene ; Referral and Consultation ; Surveys and Questionnaires ; Wound Healing
Sprache	Englisch
Erscheinungsdatum	2022-04-11
Erscheinungsland	England
Dokumenttyp	Journal Article
ZDB-ID	1353951-6
ISSN	0969-0700
ISSN	0969-0700
DOI	10.12968/jowc.2022.31.Sup4a.S1
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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