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  1. Article ; Online: Intranational differences in the case fatality rates for COVID-19 among Peruvian physicians.

    Valenzuela-Rodriguez, German / Zambrano, Lysien I / Muñoz-Lara, Fausto / Pecho-Silva, Samuel / Arteaga-Livias, Kovy / Rodriguez-Morales, Alfonso J

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2020  Volume 101, Page(s) 226–227

    Keywords covid19
    Language English
    Publishing date 2020-09-13
    Publishing country Canada
    Document type Letter
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2020.09.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: SARS-CoV-2 natural infection in animals: a systematic review of studies and case reports and series.

    Bonilla-Aldana, D Katterine / García-Barco, Alejandra / Jimenez-Diaz, S Daniela / Bonilla-Aldana, Jorge Luis / Cardona-Trujillo, Maria C / Muñoz-Lara, Fausto / Zambrano, Lysien I / Salas-Matta, Luis A / Rodriguez-Morales, Alfonso J

    The veterinary quarterly

    2021  Volume 41, Issue 1, Page(s) 250–267

    Abstract: COVID-19 pandemic is essentially a zoonotic disease. In this context, early in 2020, transmission from humans to certain animals began reporting; the number of studies has grown since. To estimate the pooled prevalence of SARS-CoV-2 natural infection in ... ...

    Abstract COVID-19 pandemic is essentially a zoonotic disease. In this context, early in 2020, transmission from humans to certain animals began reporting; the number of studies has grown since. To estimate the pooled prevalence of SARS-CoV-2 natural infection in animals and to determine differences in prevalence between countries, years, animal types and diagnostic methods (RT-PCR or serological tests). A systematic literature review with meta-analysis using eight databases. Observational studies were included but analyzed separately. We performed a random-effects model meta-analysis to calculate the pooled prevalence and 95% confidence interval (95% CI) for prevalence studies and case series. After the screening, 65 reports were selected for full-text assessment and included for qualitative and quantitative analyses. A total of 24 reports assessed SARS-CoV-2 infection by RT-PCR, combining a total of 321,785 animals, yielding a pooled prevalence of 12.3% (95% CI 11.6%-13.0%). Also, a total of 17 studies additionally assessed serological response against SARS-CoV-2, including nine by ELISA, four by PRTN, one by MIA, one by immunochromatography (rest, two studies, the method was not specified), combining a total of 5319 animals, yielding a pooled prevalence of 29.4% (95% CI 22.9%-35.9%). A considerable proportion of animals resulted infected by SARS-CoV-2, ranking minks among the highest value, followed by dogs and cats. Further studies in other animals are required to define the extent and importance of natural infection due to SARS-CoV-2. These findings have multiple implications for public human and animal health. One Health approach in this context is critical for prevention and control.
    MeSH term(s) Animals ; COVID-19/diagnosis ; COVID-19/epidemiology ; COVID-19/veterinary ; COVID-19 Testing/methods ; COVID-19 Testing/veterinary ; Prevalence ; SARS-CoV-2 ; Viral Zoonoses/diagnosis ; Viral Zoonoses/epidemiology
    Language English
    Publishing date 2021-09-10
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 754161-2
    ISSN 1875-5941 ; 0165-2176
    ISSN (online) 1875-5941
    ISSN 0165-2176
    DOI 10.1080/01652176.2021.1970280
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Assessment of Post-Dengue Rheumatic Symptoms Using the WOMAC and DAS-28 Questionnaires in a Honduran Population after a Four-Month Follow-Up.

    Zambrano, Lysien I / Fuentes-Barahona, Itzel Carolina / Portillo-Pineda, Ricardo / Aguilar-Ponce, Melissa / Murillo-Padilla, José Carlos / Suazo-Menocal, Marlen / Antunez-Salgado, Cesar / Medina-Bassilet, Edissa / Muñoz-Lara, Fausto / Bonilla-Aldana, D Katterine / Montenegro-Idrogo, Juan J / Rodríguez-Morales, Alfonso J

    Tropical medicine and infectious disease

    2022  Volume 7, Issue 12

    Abstract: Introduction: Alphaviruses may cause arthritis, but there is a lack of studies assessing it in flaviviruses such as dengue. Through the 28 Joint Disease Activity Score (DAS-28), incorporating swollen joint counts, and through the Arthritis Index from ... ...

    Abstract Introduction: Alphaviruses may cause arthritis, but there is a lack of studies assessing it in flaviviruses such as dengue. Through the 28 Joint Disease Activity Score (DAS-28), incorporating swollen joint counts, and through the Arthritis Index from Western Ontario and McMaster Universities (WOMAC), we assessed pain, stiffness, and dimensions of arthritic function in post-DENV patients. Methods: Prospective study of a cohort of participants who were diagnosed with dengue in centres in Honduras from December 2019 to February 2020, with a follow-up period of 4 months to evaluate post-dengue rheumatological disease through the WOMAC and DAS-28 questionnaires. Results: After a four-month follow-up phase with 281 participants, the final cohort comprised 58.8% women and 41.20% men. After the follow-up, 63.02% persisted with the clinical findings. According to WOMAC, joint involvement was higher in women with (58.76%) (p < 0.0001) these symptoms or functional limitations when performing daily activities were limited to pain when walking (34.81% vs. 5.51%), climbing or descending stairs (36.46% vs. 8.66%), and at night at bedtime (28.73% vs. 7.08%). With the DAS-28, we found at least one alteration with inflammation or pain in 14.91% of the participants, primarily women (p < 0.01). Discussion: Joint involvement was high during the dengue epidemic in 2019. We observed a significant proportion of women with inflammation and joint pain, showing that dengue may lead to the development of chronic rheumatological findings, although lower than in CHIKV, still affecting everyday life and, consequently, their quality of life. Additional long-term evaluation studies after dengue are required.
    Language English
    Publishing date 2022-11-23
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2414-6366
    ISSN (online) 2414-6366
    DOI 10.3390/tropicalmed7120394
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: COVID-19 and Hurricanes: The Impact of Natural Disasters during a Pandemic in Honduras, Central America.

    Zambrano, Lysien I / Fuentes-Barahona, Itzel Carolina / Henriquez-Marquez, Karla Iveth / Vasquez-Bonilla, Walter O / Sierra, Manuel / Muñoz-Lara, Fausto / Luna, Camila / Bonilla-Aldana, D Katterine / Rodriguez-Morales, Alfonso J

    Prehospital and disaster medicine

    2021  Volume 36, Issue 2, Page(s) 246–248

    MeSH term(s) COVID-19/epidemiology ; Cyclonic Storms ; Honduras/epidemiology ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/virology ; SARS-CoV-2
    Language English
    Publishing date 2021-02-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1025975-2
    ISSN 1945-1938 ; 1049-023X
    ISSN (online) 1945-1938
    ISSN 1049-023X
    DOI 10.1017/S1049023X21000182
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: A systematic review and meta-analysis of bovine brucellosis seroprevalence in Latin America and the Caribbean.

    Bonilla-Aldana, D Katterine / Trejos-Mendoza, Adrián Esteban / Pérez-Vargas, Soffia / Rivera-Casas, Estefany / Muñoz-Lara, Fausto / Zambrano, Lysien I / Arteaga-Livias, Kovy / Ulloque-Badaracco, Juan R / Alarcon-Braga, Esteban A / Hernandez-Bustamante, Enrique A / Al-Kassab-Córdova, Ali / Benites-Zapata, Vicente A / Rodriguez-Morales, Alfonso J

    New microbes and new infections

    2023  Volume 54, Page(s) 101168

    Abstract: Introduction: Bovine brucellosis is a significant public health problem in countries with economic and zoonotic implications. Although relevant, there are no previous systematic reviews about bovine brucellosis in Latin America.: Methods: We ... ...

    Abstract Introduction: Bovine brucellosis is a significant public health problem in countries with economic and zoonotic implications. Although relevant, there are no previous systematic reviews about bovine brucellosis in Latin America.
    Methods: We performed a systematic literature review in five data-bases to assess the seroprevalence of Brucella in cattle. A meta-analysis with a random-effects model was performed to calculate the pooled prevalence and 95% confidence intervals (95%CI). In addition, measures of heterogeneity (Cochran's Q statistic and I
    Results: The literature search yielded 3,403 articles, of which 65 studies were fully valid for analysis. The pooled seroprevalence for Brucella in bovine (n ​= ​46,883,177) was 4.0% (95%CI: 3.0%-5.0%; p ​< ​0.001), and Venezuela was the country with the highest prevalence (16.0%). By regions, the highest seroprevalence is in Central America and the Caribbean islands (8.0%,95%CI: 3.0%-15.0%; p ​< ​0.001, I
    Conclusions: Some countries reported still relevant seroprevalences of bovine brucellosis, especially at the Central America and Caribbean islands. Multiple factors may influence the survival and spread of pathogens in the environment; farms located in regions bordering forest areas, in areas of difficult access to the veterinary service; extensive beef herds raised at pastures with different age and productive groups inter-mingled, and minimal concerns regarding hygiene practices and disease prevention measures. Bovine brucellosis has not been eliminated and needs to be considered with new tools for prevention and control, especially being a zoonosis.
    Language English
    Publishing date 2023-08-24
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2750179-6
    ISSN 2052-2975
    ISSN 2052-2975
    DOI 10.1016/j.nmni.2023.101168
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: SARS-CoV-2 natural infection in animals: a systematic review of studies and case reports and series

    Bonilla-Aldana, D. Katterine / García-Barco, Alejandra / Jimenez-Diaz, S. Daniela / Bonilla-Aldana, Jorge Luis / Cardona-Trujillo, Maria C. / Muñoz-Lara, Fausto / Zambrano, Lysien I. / Salas-Matta, Luis A. / Rodriguez-Morales, Alfonso J.

    Veterinary quarterly. 2021 Dec. 15, v. 41, no. 1

    2021  

    Abstract: COVID-19 pandemic is essentially a zoonotic disease. In this context, early in 2020, transmission from humans to certain animals began reporting; the number of studies has grown since. To estimate the pooled prevalence of SARS-CoV-2 natural infection in ... ...

    Abstract COVID-19 pandemic is essentially a zoonotic disease. In this context, early in 2020, transmission from humans to certain animals began reporting; the number of studies has grown since. To estimate the pooled prevalence of SARS-CoV-2 natural infection in animals and to determine differences in prevalence between countries, years, animal types and diagnostic methods (RT-PCR or serological tests). A systematic literature review with meta-analysis using eight databases. Observational studies were included but analyzed separately. We performed a random-effects model meta-analysis to calculate the pooled prevalence and 95% confidence interval (95% CI) for prevalence studies and case series. After the screening, 65 reports were selected for full-text assessment and included for qualitative and quantitative analyses. A total of 24 reports assessed SARS-CoV-2 infection by RT-PCR, combining a total of 321,785 animals, yielding a pooled prevalence of 12.3% (95% CI 11.6%–13.0%). Also, a total of 17 studies additionally assessed serological response against SARS-CoV-2, including nine by ELISA, four by PRTN, one by MIA, one by immunochromatography (rest, two studies, the method was not specified), combining a total of 5319 animals, yielding a pooled prevalence of 29.4% (95% CI 22.9%–35.9%). A considerable proportion of animals resulted infected by SARS-CoV-2, ranking minks among the highest value, followed by dogs and cats. Further studies in other animals are required to define the extent and importance of natural infection due to SARS-CoV-2. These findings have multiple implications for public human and animal health. One Health approach in this context is critical for prevention and control.
    Keywords COVID-19 infection ; One Health initiative ; Severe acute respiratory syndrome coronavirus 2 ; confidence interval ; immunoaffinity chromatography ; meta-analysis ; statistical models ; systematic review ; zoonoses
    Language English
    Dates of publication 2021-1215
    Size p. 250-267.
    Publishing place Taylor & Francis
    Document type Article
    ZDB-ID 754161-2
    ISSN 1875-5941 ; 0165-2176
    ISSN (online) 1875-5941
    ISSN 0165-2176
    DOI 10.1080/01652176.2021.1970280
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: High impact of SARS-CoV-2 or COVID-19 in the Honduran health personnel.

    Henriquez-Marquez, Karla Iveth / Lainez-Murillo, Doris Carolina / Sierra, Manuel / Muñoz-Lara, Fausto / Valenzuela-Rodriguez, German / Pecho-Silva, Samuel / Arteaga-Livias, Kovy / Zambrano, Lysien I / Rodriguez-Morales, Alfonso J

    Journal of medical virology

    2020  Volume 93, Issue 4, Page(s) 1885–1887

    MeSH term(s) Adult ; COVID-19/epidemiology ; Health Personnel/statistics & numerical data ; Honduras/epidemiology ; Humans ; Prevalence ; Young Adult
    Language English
    Publishing date 2020-12-17
    Publishing country United States
    Document type Letter
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.26702
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A review of the main histopathological findings in coronavirus disease 2019.

    Vasquez-Bonilla, Walter O / Orozco, Roberto / Argueta, Víctor / Sierra, Manuel / Zambrano, Lysien I / Muñoz-Lara, Fausto / López-Molina, Dennis Salomón / Arteaga-Livias, Kovy / Grimes, Zachary / Bryce, Clare / Paniz-Mondolfi, Alberto / Rodríguez-Morales, Alfonso J

    Human pathology

    2020  Volume 105, Page(s) 74–83

    Abstract: Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, has been declared by the World Health Organization as an emerging public health problem of global importance and classified as a ... ...

    Abstract Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, has been declared by the World Health Organization as an emerging public health problem of global importance and classified as a pandemic. SARS-CoV-2 infection can result in diverse, multiorgan pathology, the most significant being in the lungs (diffuse alveolar damage in its different phases, microthrombi, bronchopneumonia, necrotizing bronchiolitis, viral pneumonia), heart (lymphocytic myocarditis), kidney (acute tubular injury), central nervous system (microthrombi, ischemic necrosis, acute hemorrhagic infarction, congestion, and vascular edema), lymph nodes (hemophagocytosis and histiocytosis), bone marrow (hemophagocytosis), and vasculature (deep vein thrombosis). An understanding of the spectrum and frequency of histologic findings in COVID-19 is essential for gaining a better understanding of disease pathophysiology and its ongoing impact on public health. To this end, we conducted a systematic meta-analysis of histopathologic observations to date and review the reported findings.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Autopsy ; Biopsy ; Blood Vessels/pathology ; COVID-19/pathology ; Central Nervous System/pathology ; Female ; Humans ; Kidney/pathology ; Lung/pathology ; Lymph Nodes/pathology ; Male ; Middle Aged ; Myocardium/pathology ; SARS-CoV-2 ; Thromboembolism/pathology
    Keywords covid19
    Language English
    Publishing date 2020-08-02
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 207657-3
    ISSN 1532-8392 ; 0046-8177
    ISSN (online) 1532-8392
    ISSN 0046-8177
    DOI 10.1016/j.humpath.2020.07.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Intranational differences in the case fatality rates for COVID-19 among Peruvian physicians

    Valenzuela-Rodriguez, German / Zambrano, Lysien I / Muñoz-Lara, Fausto / Pecho-Silva, Samuel / Arteaga-Livias, Kovy / Rodriguez-Morales, Alfonso J

    Int J Infect Dis

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #753453
    Database COVID19

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  10. Article ; Online: Intranational differences in the case fatality rates for COVID-19 among Peruvian physicians

    Valenzuela-Rodriguez, German / Zambrano, Lysien I. / Muñoz-Lara, Fausto / Pecho-Silva, Samuel / Arteaga-Livias, Kovy / Rodriguez-Morales, Alfonso J.

    International Journal of Infectious Diseases

    2020  Volume 101, Page(s) 226–227

    Keywords Microbiology (medical) ; Infectious Diseases ; General Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2020.09.018
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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