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  1. Article ; Online: COMMONLY ISOLATED ORGANISM IN DIABETIC FOOT AND ITS ANTIBIOTIC SENSITIVITY, AN EXPERIENCE AT TERTIARY CARE HOSPITAL

    Muhammad Iqbal Khan / Riffat Arbab.

    Journal of University Medical & Dental College, Vol 11, Iss 1, Pp 23-

    2020  Volume 30

    Abstract: BACKGROUND & OBJECTIVE: To determine the commonly isolated organism in ulcers of diabetic foot and its sensitivity to antibiotics. METHODOLOGY: A total of 167 patients of diabetic foot were included in this descriptive Crosssectional study. All the ... ...

    Abstract BACKGROUND & OBJECTIVE: To determine the commonly isolated organism in ulcers of diabetic foot and its sensitivity to antibiotics. METHODOLOGY: A total of 167 patients of diabetic foot were included in this descriptive Crosssectional study. All the patients were informed and consent was obtained according to ethical criteria approved by the ethical committee. The use of antibiotics in last 72 hours was strictly observed. The samples were obtained under aseptic conditions by applying the swap slightly to the exudate or base of the ulcer and were then carefully transferred in to the container and were then sent to the laboratory on the same date. The culture sensitivity was performed. Data was analyzed using SPSS. 20. RESULTS: A total of 140 samples were positive for 8 types of bacteria out of 167. 94 samples were monomicrobial were as 46 were polymicrobial. Over all Staphylococcus aureus 63(40.3%) was the most commonly isolated bacteria followed by Pseudomonas aeruginosa 40 (25.6%). S. aureus was most sensitive to imipenem/ meropenem (79.3%) followed by vancomycin (71%), linezolid (69.8%) and moxifloxacin (69.8%). P. aeruginosa was sensitive to impenem/ meropeneum (90%) followed by Ticarcilline/ clavulante (92.5%), amikacin (87.5%) and pipracilline / tazobactom (80%). Most of the gram positive and negative bacteria were resistant to commonly available antibiotic like ampiciline/ cloxacillin, amoxicilline/ clavulante and cephradine. CONCLUSION: Most of the commonly used antibiotics had developed resistance. was S. aureus most common bacteria from the isolates and was sensitive to impenem/meropenem, vancomycin and linezolid. Gram-negative bacteria showed sensitivity to impenem/meropeneum, pipracilline/ tazobactom, Ticarcilline/ clavulante and amikacin.
    Keywords diabetic foot ; diabetes mellitus ; antibiotic sensitivity ; Medicine ; R
    Subject code 540
    Language English
    Publishing date 2020-03-01T00:00:00Z
    Publisher University of Faisalabad
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: STRATEGY FOR RESUMING ELECTIVE SURGICAL PROCEDURES DURING & AFTER COVID-19 PANDEMIC

    Muhammad Iqbal Khan / Shabir Ahmed Lehri / Riffat Arbab

    Journal of University Medical & Dental College, Vol 12, Iss

    2021  Volume 2

    Abstract: ABSTRACT COVID-19 pandemic has afflicted the individuals, national economies, and healthcare system worldwide. It has badly struck the ongoing and planned surgical procedures in nearly all healthcare centers which has led the surgical procedures to come ... ...

    Abstract ABSTRACT COVID-19 pandemic has afflicted the individuals, national economies, and healthcare system worldwide. It has badly struck the ongoing and planned surgical procedures in nearly all healthcare centers which has led the surgical procedures to come to a grinding halt. This serious issue invites comments from surgical experts throughout the world.
    Keywords Elective Surgeries ; COVID-19 ; Operating room (OR) ; Medicine ; R
    Language English
    Publishing date 2021-05-01T00:00:00Z
    Publisher University of Faisalabad
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Duodenal ulcer perforation and its consequences

    Mariam Malik / Abdul Malik Magsi / Sughra Parveen / Muhammad Iqbal Khan / Mazhar Iqbal

    Journal of the Pakistan Medical Association, Vol 73, Iss

    2023  Volume 7

    Abstract: Duodenal ulcer perforation, a frequent surgical emergency, needs simple closure with indirect Graham’s Omentopexy which is effective with excellent results in majority of cases despite patients’ late presentation. The objective of the study was to ... ...

    Abstract Duodenal ulcer perforation, a frequent surgical emergency, needs simple closure with indirect Graham’s Omentopexy which is effective with excellent results in majority of cases despite patients’ late presentation. The objective of the study was to determine the frequency of postoperative complications of perforated duodenal ulcer, conducted in the Surgery Department, Jinnah Postgraduate Medical Centre, Karachi, from March 20, 2018 to September 20, 2018. The study was a descriptive case series of 108 patients of both genders with perforated duodenal ulcer > 1 week old with ASA score I & II. Patients with trauma and co-morbidities were excluded. The patients underwent laparotomy and peritoneal toilet, and after noting the site of perforation indirect Graham’s Omentopexy was performed. Complications like duodenal fistula, peritonitis, and paralytic ileus, and patient’s death within 10 days of surgery were noted. ---Continue
    Keywords Medicine ; R
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher Pakistan Medical Association
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Management of Fournier’s Gangrene at postgraduate medical institute Sandeman provincial Hospital Quetta

    Anwar Lehri / Muhammad Iqbal Khan Khan / Riffat Arbab / Lailama Shah / Shabir Ahmed Lehri / Hafsa Jaffar

    Journal of University Medical & Dental College, Vol 13, Iss

    2022  Volume 2

    Abstract: BACKGROUND & OBJECTIVE: Fournier's Gangrene is a quick development of necrotizing, fulminant infection of the scrotum, perineum, and lower abdominal wall and can involve the groin. Synergic aerobic and anaerobic organisms can cause this disease. The aim ... ...

    Abstract BACKGROUND & OBJECTIVE: Fournier's Gangrene is a quick development of necrotizing, fulminant infection of the scrotum, perineum, and lower abdominal wall and can involve the groin. Synergic aerobic and anaerobic organisms can cause this disease. The aim of this study is to evaluate the causes, complications and optimal treatment of Fournier’s Gangrene. METHODOLOGY: A total of 150 patients were included. Fournier’s Gangrene was diagnosed clinically. Detailed clinical examination was performed, and the complications and modes of treatment were recorded. Calculation of descriptive statistics was done by the stratification and application of independent T-test and Chi-square test wherever applicable for post-stratification, considering p-value ≤0.05 as significant. RESULTS: The mean age was 31.74±6.24 years. The most common presenting complaint was the dusky appearance of the overlying skin. In the diabetic group, (66)44% had intense genital pain and tenderness, while in the non-diabetic group (72)48% observed a dusky appearance of the overlying skin and (37)24.7% had morbid obesity. No significant association was found between mortality of study groups, their age groups and their duration of hospital stay. CONCLUSION: Most common presenting complaint was the dusky appearance of the overlying skin. The anal abscess was the most common etiology, followed by a strangulated inguinal hernia. The mortality rate was 24%.
    Keywords Fournier’s Gangrene ; Causes ; Complications ; Mode of ; Medicine ; R
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher University of Faisalabad
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: PREOPERATIVE ASSESSMENT OF SCORING SYSTEM DESIGNED FOR PREDICTION OF DIFFICULT CHOLECYSTECTOMY IN PATIENTS WITH SYMPTOMATIC GALL STONES

    Abdullah Iqbal / Sughra Perveen / Imran Khan / Tanweer Ahmed / Muhammad Iqbal Khan / Mehwish Tunio

    Pakistan Armed Forces Medical Journal, Vol 70, Iss 2, Pp 610-

    2020  Volume 616

    Abstract: Objective: To carry out preoperative assessment of scoring system designed for prediction of difficult cholecystectomy in patients with symptomatic gall stones. Study Design: Prospective observational study. Place and Duration of Study: The study was ... ...

    Abstract Objective: To carry out preoperative assessment of scoring system designed for prediction of difficult cholecystectomy in patients with symptomatic gall stones. Study Design: Prospective observational study. Place and Duration of Study: The study was conducted in General Surgery Unit 1, ward 3, JPMC, from Jun 2017 to Aug 2018. Methodology: During the study, 208 patients were enrolled who presented for the elective cholecystectomy. Personal data, comorbid illness, sonographic, clinical and biochemical parameters were assessed. Based on the preoperative scoring, outcome measure was easy, difficult or very difficult cholecystectomy. Results: On the basis of preoperative assessment and scoring, 157 (75.5%) patients were preoperatively predicted for easy cholecystectomy whereas 51 (24.5%) patients were predicted for difficult cholecystectomy. Sensitivity and specificity of this scoring method were 96.5% and 68.5% respectively. Positive predictive value of this scoring method was 89.1% and 72.5% for easy and difficult cases, respectively. Conclusion: The scoring system proposed in our study incorporating all the known factors for difficult cholecystectomy does provide a definite, objective and reliable prediction of difficult case pre operatively.
    Keywords difficult cholecystectomy ; laparoscopic cholecystectomy ; Medicine ; R ; Medicine (General) ; R5-920
    Language English
    Publishing date 2020-04-01T00:00:00Z
    Publisher Army Medical College Rawalpindi
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: FREQUENCY OF SUBCLINICAL HYPOTHYROIDISM AMONG DIAGNOSED CASES OF CHOLELITHIASIS.

    Riffat Arbab / Muhammad iqbal Khan / Abdullah Khan / Maria Mehmood / Aisha Arshad / Hafsa Qazi

    Journal of University Medical & Dental College, Vol 11, Iss

    2020  Volume 3

    Abstract: Abstract BACKGROUND & OBJECTIVE: Thyroid hormones act as foundation for the normal functioning of all the body hormones and body metabolism. The abnormality of thyroid hormones may lead to deranged lipid metabolism with abnormal relaxation of sphincter ... ...

    Abstract Abstract BACKGROUND & OBJECTIVE: Thyroid hormones act as foundation for the normal functioning of all the body hormones and body metabolism. The abnormality of thyroid hormones may lead to deranged lipid metabolism with abnormal relaxation of sphincter of oddi. This will cause stasis of bile in gallbladder and biliary channels leading to stone formation. The objective of the study is to determine the frequency of subclinical hypothyroidism among diagnosed cases of Cholelithiasis. METHODOLOGY: This study was conducted in Surgical Department, Sandman Provincial Hospital Quetta, from January to December 2018. The study has been approved by the ethical review committee of Post Graduate Medical Institute Quetta. It is a cross-sectional study. A total of 193 patients with Cholelithiasis were included in the study. After informed written consent, blood was sent to laboratory for testing the levels of serum TSH, T3 and T4. Samples having TSH values more than 6.0mU/L and serum thyroxin within the normal range 9.0-19.0pmole/L, were labeled as subclinical hypothyroidism. RESULTS: The data of all the patients between 35 to 62 years of age with Cholelithiasis during the study period was taken and analysis was performed. The inclusion and exclusion criteria were strictly considered. Mean ± SD of age was 47.03±5.401 with C.I (46.26-47.80) years. Out of 193 patients 25 (13%) were male and 168(87%) were female. Subclinical hypothyroidism was found to be in 16 (8.16%) patients and remaining 177(91.70%) patients were found normal. CONCLUSION: It was concluded that the incidence of subclinical hypothyroidism in Cholelithiasis patients is low.
    Keywords Cholelithiasis ; subclinical hypothyroidism ; Disease Management ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2020-10-01T00:00:00Z
    Publisher University of Faisalabad
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Clinical Course of Colorectal Carcinoma in a Developing Country

    Muhammad Iqbal Khan

    Journal of Rawalpindi Medical College, Vol 13, Iss

    2009  Volume 1

    Abstract: Background: To study the clinical presentation of colo-rectal carcinoma in a developing country. Methods: In this non- interventional descriptive study, 75 patients were diagnosed to have color-rectal carcinoma in the eight years between November 1997 ... ...

    Abstract Background: To study the clinical presentation of colo-rectal carcinoma in a developing country. Methods: In this non- interventional descriptive study, 75 patients were diagnosed to have color-rectal carcinoma in the eight years between November 1997 and December 2005. All the presenting features were recorded in a proforma. Detailed family history of gastro-intestinal or extra gastro-intestinal malignancy was obtained. Enquiry was made about the known risk factors of colo-rectal carcinoma. The information was analyzed to identify the common presenting features and role of known risk factors in the pathogenesis of disease. Results: Bleeding per rectum was the commonest presentation. However, surgical emergency was the second most common presentation in our study. The disease was found to be most common below fifty years of age. Rectosigmoid region (57%) was the commonest site. Histologically fifty perent of cases revealed well – differentiated morphology. Known environmental factors had no significant role in pathogenesis of the disease. Conclusion: Colorectal carcinoma is a disease of younger age in our society. Screening programs should include patients below 50 years of age.
    Keywords Colorectal carcinoma ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2009-06-01T00:00:00Z
    Publisher Rawalpindi Medical University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Nutritional and fatty acid profile of human milk samples from district Malakand, Pakistan

    Muhammad Adil / Kashmala Majid / Kashif Gul / Zawar Hussain / Inayatur Rahman / Muhammad Iqbal Khan / Murad Ali Khan

    Pakistan Journal of Analytical & Environmental Chemistry, Vol 21, Iss 2, Pp 263-

    2020  Volume 270

    Abstract: Generally, breast milk is the first and complete diet for an infant. It has a pivotal role in determining the growth pattern of the kids. Breast milk has various nutritional ingredients and is a source of energy for the infants. It has a vital role in ... ...

    Abstract Generally, breast milk is the first and complete diet for an infant. It has a pivotal role in determining the growth pattern of the kids. Breast milk has various nutritional ingredients and is a source of energy for the infants. It has a vital role in the development of the immune system. The composition of milk varies with the diet of the mother, environment, and time of feeding. The fatty acid profile and nutritional value of the breast milk of the Malakand district were determined. The fats and protein were determined using the recommended methods by the Association of Official Analytical Chemists (AOAC) and Ward method, respectively while the fatty acid profile was determined through GC-MS. Milk samples were analyzed for proximate composition and from the results the moisture content was 87.69%, ash 0.29%, fats 3.63%, protein 0.94%, and carbohydrate content ware 7.45%. The average fatty acid profiles of milk showed that it is composed of saturated (SFA), monounsaturated (MUFA) and polyunsaturated fatty acid (PUFA) with a concentration of 38.41%, 29.59%, and 14.70%, respectively. In general, both proximate and fatty acid profiles were found slightly different compared to the contents of breast milk in developed countries which may be due to the difference in diet, environment, and socioeconomic status of women in Pakistan.
    Keywords human milk ; proximate composition ; fatty acids profile ; Environmental sciences ; GE1-350 ; Analytical chemistry ; QD71-142
    Subject code 571
    Language English
    Publishing date 2020-12-01T00:00:00Z
    Publisher National Centre of Excellence in Analytical Chemsitry
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Comparison of the Restoration of Breast Feeding after Percutaneous Aspiration vs Incision and Drainage for Management of Breast Abscess

    Noor Hussain / Imran Khan / Tanweer Ahmed / Sughra Parveen / Mariam Malik / Muhammad Iqbal Khan

    JLUMHS, Vol 17, Iss 01, Pp 47-

    2018  Volume 51

    Abstract: BACKGROUND: Mastitis is not uncommon among lactating woman. This is caused by local inflammation and/or infection of terminal lactiferous ducts. Incision and drainage followed by postoperative antibiotics is the treatment of choice for such abscesses ... ...

    Abstract BACKGROUND: Mastitis is not uncommon among lactating woman. This is caused by local inflammation and/or infection of terminal lactiferous ducts. Incision and drainage followed by postoperative antibiotics is the treatment of choice for such abscesses depending on culture and sensitivity. Ultrasound guided needle aspiration is also effective for breast abscesses. OBJECTIVE: To compare the outcome of percutaneous aspiration with incision drainage for management of breast abscess among lactating mothers. METHODOLOGY: This comparative study was carried out at Jinnah Postgraduate Medical Centre, Karachi, Pakistan from August 2015 to August 2016. A total of 90 women with breast abscess were included according to inclusion and exclusion criteria. These women were randomly allocated into two groups. Forty-five in group A, treated with percutaneous aspiration, and 45 patients in group B treated with incision and drainage for breast abscess. Percutaneous aspiration was done after radiological estimation of size, site and shape. After the intervention, all the patients were observed for the outcome parameter i.e. early restoration of breast feeding, as if the mother starts feeding the baby within 24 hours after the procedure All the information was collected on a specially designed Performa. RESULTS: Rate of early restoration of breast feeding was significantly high in group A (percutaneous aspiration) as compared to group B (drainage for breast abscess) [82.2% vs. 57.8%); 0.011]. CONCLUSION: We conclude that percutaneous aspiration of breast abscess is a minimally invasive, simple outpatient procedure without the need of general anesthesia with superior cosmetic results and high satisfaction rate.
    Keywords mastitis ; percutaneous aspiration ; lactating mothers ; breast abscess ; Medicine ; R
    Subject code 616
    Language English
    Publishing date 2018-01-01T00:00:00Z
    Publisher Liaquat University of Medical and Health Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Causes of Acute Peritonitis and its Outcome in Tertiary Medical Centre

    Mariam Malik / Mazhar Iqbal / Abdul Malik Magsi / Sughra Parveen / Muhammad Iqbal Khan / Munazza Shamim / Shoaib Malik

    JLUMHS, Vol 18, Iss 03, Pp 193-

    2019  Volume 196

    Abstract: OBJECTIVE: To determine the factors causing peritonitis and deaths at Jinnah Hospital Karachi. METHODOLOGY: The study included 216 patients with acute peritonitis who underwent exploratory laparotomy from 2016 to 2018. Surgical treatment according to ... ...

    Abstract OBJECTIVE: To determine the factors causing peritonitis and deaths at Jinnah Hospital Karachi. METHODOLOGY: The study included 216 patients with acute peritonitis who underwent exploratory laparotomy from 2016 to 2018. Surgical treatment according to cause and post-operative treatment of disease carried out. Histopathological report and other diagnostic test like typhoid dot test and blood culture results were recorded and resultwas analyzed by SPSS version 24. RESULTS: Frequent causes of acute peritonitis were typhoid intestinal perforation 62(28.70%),Peptic ulcer perforation 54 (25%), rupture appendix 38 (17.59%), tuberculous intestine perforation 26 (12.05%), gangrene gut 14 (6.48%), large gut tumor perforation 10 (4.62%), ruptured liver abscess 4 (1.85%), ruptured gall balder 4 (1.85%) and acute pancreatitis 4 (1.85%). Complications were septic shock 30 (13.88%), paralytic ileus 16 (7.40%), burst abdomen 12 (5.5%) and mortality was 8 (3.70%.) CONCLUSION: Infectious diseases like typhoid, H-pylori PUD, ruptured appendix, ruptured liver abscess, and TB intestine are common causes of peritonitis.
    Keywords perforation peritonitis ; typhoid ileal perforation ; duodenal ulcer perforation ; Medicine ; R
    Language English
    Publishing date 2019-09-01T00:00:00Z
    Publisher Liaquat University of Medical and Health Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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