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  1. Article: The Buzz Surrounding Precision Medicine: The Imperative of Incorporating It into Evidence-Based Medical Practice.

    Muharremi, Guido / Meçani, Renald / Muka, Taulant

    Journal of personalized medicine

    2023  Volume 14, Issue 1

    Abstract: Precision medicine (PM), through the integration of omics and environmental data, aims to provide a more precise prevention, diagnosis, and treatment of disease. Currently, PM is one of the emerging approaches in modern healthcare and public health, with ...

    Abstract Precision medicine (PM), through the integration of omics and environmental data, aims to provide a more precise prevention, diagnosis, and treatment of disease. Currently, PM is one of the emerging approaches in modern healthcare and public health, with wide implications for health care delivery, public health policy making formulation, and entrepreneurial endeavors. In spite of its growing popularity and the buzz surrounding it, PM is still in its nascent phase, facing considerable challenges that need to be addressed and resolved for it to attain the acclaim for which it strives. In this article, we discuss some of the current methodological pitfalls of PM, including the use of big data, and provide a perspective on how these challenges can be overcome by bringing PM closer to evidence-based medicine (EBM). Furthermore, to maximize the potential of PM, we present real-world illustrations of how EBM principles can be integrated into a PM approach.
    Language English
    Publishing date 2023-12-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662248-8
    ISSN 2075-4426
    ISSN 2075-4426
    DOI 10.3390/jpm14010053
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The Use of Psychoactive Substances and Illegal Drugs in the Albanian Society.

    Matua, Linda / Muharremi, Guido / Petrela, Elizana / Koçibelli, Mirnela / Vyshka, Gentian / Xhemali, Bledar

    Current drug research reviews

    2018  Volume 11, Issue 1, Page(s) 73–79

    Abstract: Background: To create a representative picture of the prevalence and the total number of drug users in Albania from 2012 to 2016, and compare those numbers to previous years with other available data.: Methods: The required data for the conductance ... ...

    Abstract Background: To create a representative picture of the prevalence and the total number of drug users in Albania from 2012 to 2016, and compare those numbers to previous years with other available data.
    Methods: The required data for the conductance of this study was collected from three different fronts, namely The Institute of Forensic Medicine (IFM), Clinical Toxicology and Addictions Service, University Hospital "Mother Theresa" Tirana (CTS) and Methadone Maintenance Treatment Centers. The study targets all individuals who have consumed at least once abusive drugs and psychotropic substances during the period 2012-2016 in the Republic of Albania. A total of 7050 reported cases over the given period were reviewed.
    Results: Overall, Cannabis Sativa was the highest consumed drug, present in 62.58% of the cases. Other substances with a noticeable prevalence of use were heroin (15.02%) and cocaine (5.1%). It was found out that there were 36 drug-related deaths from 2012 to 2016. During this period of time, only 9 individuals resulted positive for Sexually Transmitted Infections (STI), of which, one positive for Hepatitis C and the remaining 8 positives for HIV. About 25% of drug users in Albania belong to the young subgroup of the population (13-32 years old).
    Conclusion: Overall, taking into consideration all three databases, the number of drug users has significantly increased. There are more officially reported drug users today compared to 2012, however, different trends are observed during different periods. Youngsters are more eager and tempted to use and experiment more with safer and less harmful drugs like cannabis, meanwhile, as age increases, there is a tendency to shift towards more potent and dangerous drugs. Prevention and reducing the prevalence of use of psychoactive drugs is one of the main goals of public health.
    MeSH term(s) Adolescent ; Adult ; Albania/epidemiology ; Drug Users/statistics & numerical data ; Female ; Health Surveys ; Humans ; Male ; Middle Aged ; Prevalence ; Psychotropic Drugs ; Street Drugs ; Substance-Related Disorders/epidemiology ; Young Adult
    Chemical Substances Psychotropic Drugs ; Street Drugs
    Language English
    Publishing date 2018-09-19
    Publishing country United Arab Emirates
    Document type Journal Article
    ISSN 2589-9783
    ISSN (online) 2589-9783
    DOI 10.2174/1874473711666180719141731
    Database MEDical Literature Analysis and Retrieval System OnLINE

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