LIVIVO - Search results -

Search results

Result 1 - 10 of total 23

Search options

Article: Antibody Therapeutics as Interfering Agents in Flow Cytometry Crossmatch for Organ Transplantation.

Kueht, Michael L / Dongur, Laxmi Priya / Mujtaba, Muhammad A / Cusick, Matthew F

2023 Volume 13, Issue 6

Abstract: Donor-recipient matching is a highly individualized and complex component of solid organ transplantation. Flowcytometry crossmatching (FC-XM) is an integral step in the matching process that is used to detect pre-formed deleterious anti-donor ... ...

Abstract	Donor-recipient matching is a highly individualized and complex component of solid organ transplantation. Flowcytometry crossmatching (FC-XM) is an integral step in the matching process that is used to detect pre-formed deleterious anti-donor immunoglobulin. Despite high sensitivity in detecting cell-bound immunoglobulin, FC-XM is not able to determine the source or function of immunoglobulins detected. Monoclonal antibody therapeutic agents used in a clinic can interfere with the interpretation of FC-XM. We combined data from the prospectively maintained Antibody Society database and Human Protein Atlas with a comprehensive literature review of PubMed to summarize known FC-XM-interfering antibody therapeutics and identify potential interferers. We identified eight unique FC-XM-interfering antibody therapeutics. Rituximab (anti-CD20) was the most-cited agent. Daratumuab (anti-CD38) was the newest reported agent. We identified 43 unreported antibody therapeutics that may interfere with FC-XM. As antibody therapeutic agents become more common, identifying and mitigating FC-XM interference will likely become an increased focus for transplant centers.
Language	English
Publishing date	2023-06-16
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662248-8
ISSN	2075-4426
ISSN	2075-4426
DOI	10.3390/jpm13061005
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article: Kidney Allograft Monitoring by Combining Donor-Derived Cell-Free DNA and Molecular Gene Expression: A Clinical Management Perspective.

Rizvi, Asim / Faiz, Sara / Thakkar, Parin H / Hussain, Syed / Gamilla-Crudo, Ann N / Kueht, Michael / Mujtaba, Muhammad A

Journal of personalized medicine

2023 Volume 13, Issue 8

Abstract: Donor-derived cell-free DNA (dd-cfDNA) may safely assess kidney allograft rejection. Molecular Microscope ( ... ...

Abstract	Donor-derived cell-free DNA (dd-cfDNA) may safely assess kidney allograft rejection. Molecular Microscope (MMDx
Language	English
Publishing date	2023-07-29
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662248-8
ISSN	2075-4426
ISSN	2075-4426
DOI	10.3390/jpm13081205
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: A case series of perioperative anaphylaxis to cefazolin during kidney transplant and review of literature.

Salehin, Salman / Kumar, Anand / Harsell, Nantian / Salim, Hamza / Hussain, Syed A / Kueht, Michael / Mujtaba, Muhammad A

Transplant immunology

2022 Volume 75, Page(s) 101720

Abstract: Background: Intraoperative anaphylaxis is a life threatening and multiorgan system hypersensitivity reaction that frequently leads to cessation of operations. Despite the incidence of Cefazolin allergy being on the rise, the cases of anaphylaxis to ... ...

Abstract	Background: Intraoperative anaphylaxis is a life threatening and multiorgan system hypersensitivity reaction that frequently leads to cessation of operations. Despite the incidence of Cefazolin allergy being on the rise, the cases of anaphylaxis to Cefazolin during surgeries and its management are seldom reported. Case presentation: We present two patients with no known beta-lactam allergy and end stage kidney disease who received perioperative intravenous Cefazolin for planned deceased kidney transplant surgery at our academic medical center. Both patients developed anaphylaxes approximately three minutes following the administration of the antibiotic and experienced severe, refractory hypotension that required the use of vasopressors. The severity of the anaphylactic reactions resulted in the cessation of the transplant operation and multiple days of intensive care unit admission. Conclusion: Peri-or intraoperative anaphylaxis to Cefazolin is on the rise and its consequences in transplant candidates are even more dire given the pre-existing end organ failure, financial burden for health care system, potential loss of donor organs, and emotional burden for recipients and their families. These are the first two cases of reported Cefazolin-induced anaphylaxis that actually resulted in aborting the kidney transplant operation. In addition, cases of previously reported Type 1 hypersensitivity to Cefazolin as prophylaxis for operations were reviewed and the allergy workups were discussed.
MeSH term(s)	Humans ; Cefazolin/adverse effects ; Anaphylaxis/chemically induced ; Anaphylaxis/complications ; Kidney Transplantation/adverse effects ; Skin Tests/adverse effects ; Drug Hypersensitivity/drug therapy ; Drug Hypersensitivity/etiology
Chemical Substances	Cefazolin (IHS69L0Y4T)
Language	English
Publishing date	2022-09-17
Publishing country	Netherlands
Document type	Review ; Case Reports
ZDB-ID	1160846-8
ISSN	1878-5492 ; 0966-3274
ISSN (online)	1878-5492
ISSN	0966-3274
DOI	10.1016/j.trim.2022.101720
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 3784: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article: Terlipressin in combination with albumin as a therapy for hepatorenal syndrome in patients aged 65 years or older.

Mujtaba, Muhammad A / Gamilla-Crudo, Ann Kathleen / Merwat, Shehzad N / Hussain, Syed A / Kueht, Michael / Karim, Aftab / Khattak, Muhammad W / Rooney, Peggy J / Jamil, Khurram

Annals of hepatology

2023 Volume 28, Issue 5, Page(s) 101126

Abstract: Introduction and objectives: Clinical data for older patients with advanced liver disease are limited. This post hoc analysis evaluated the efficacy and safety of terlipressin in patients aged ≥65 years with hepatorenal syndrome using data from 3 Phase ... ...

Abstract	Introduction and objectives: Clinical data for older patients with advanced liver disease are limited. This post hoc analysis evaluated the efficacy and safety of terlipressin in patients aged ≥65 years with hepatorenal syndrome using data from 3 Phase III, randomized, placebo-controlled studies (OT-0401, REVERSE, CONFIRM). Patients and methods: The pooled population of patients aged ≥65 years (terlipressin, n = 54; placebo, n = 36) was evaluated for hepatorenal syndrome reversal-defined as a serum creatinine level ≤1.5 mg/dL (≤132.6 μmol/L) while receiving terlipressin or placebo, without renal replacement therapy, liver transplantation, or death-and the incidence of renal replacement therapy (RRT). Safety analyses included an assessment of adverse events. Results: Hepatorenal syndrome reversal was almost 2-times higher in terlipressin-treated patients compared with patients who received placebo (31.5% vs 16.7%; P = 0.143). Among surviving patients, the need for RRT was significantly reduced in the terlipressin group, with an almost 3-times lower incidence of RRT versus the placebo group (Day 90: 25.0% vs 70.6%; P = 0.005). Among 23 liver-transplant-listed patients, significantly fewer patients in the terlipressin versus placebo group needed RRT by Days 30 and 60 (P = 0.027 each). Fewer patients in the terlipressin group needed RRT post-transplant (P = 0.011). More terlipressin-treated patients who were listed for and received a liver transplant were alive and RRT-free by Day 90. No new safety signals were revealed in the older subpopulation compared with previously published data. Conclusions: Terlipressin therapy may lead to clinical improvements in highly vulnerable patients aged ≥65 years with hepatorenal syndrome. Clinical trial numbers: OT-0401, NCT00089570; REVERSE, NCT01143246; CONFIRM, NCT02770716.
MeSH term(s)	Humans ; Terlipressin/adverse effects ; Vasoconstrictor Agents/adverse effects ; Hepatorenal Syndrome/diagnosis ; Hepatorenal Syndrome/drug therapy ; Lypressin/adverse effects ; Albumins/adverse effects ; Treatment Outcome
Chemical Substances	Terlipressin (7Z5X49W53P) ; Vasoconstrictor Agents ; Lypressin (50-57-7) ; Albumins
Language	English
Publishing date	2023-06-10
Publishing country	Mexico
Document type	Journal Article
ZDB-ID	2188733-0
ISSN	1665-2681
ISSN	1665-2681
DOI	10.1016/j.aohep.2023.101126
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6221: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Existing Transplant Nephrology Compensation Models and Opportunities for Equitable Pay.

Josephson, Michelle A / Wiseman, Alexander C / Tucker, J Kevin / Segal, Mark S / Schmidt, Rebecca J / Mujtaba, Muhammad A / Gurley, Susan B / Gaston, Robert S / Doshi, Mona D / Brennan, Daniel C / Moe, Sharon M

Clinical journal of the American Society of Nephrology : CJASN

2022 Volume 17, Issue 9, Page(s) 1407–1409

MeSH term(s)	Humans ; Nephrology ; Kidney Failure, Chronic/surgery ; Kidney Transplantation ; Nephrectomy
Language	English
Publishing date	2022-08-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	2226665-3
ISSN	1555-905X ; 1555-9041
ISSN (online)	1555-905X
ISSN	1555-9041
DOI	10.2215/CJN.02010222
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6584: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: The Importance of Transplant Nephrology to a Successful Kidney Transplant Program.

Moe, Sharon M / Brennan, Daniel C / Doshi, Mona D / Gaston, Robert S / Gurley, Susan B / Mujtaba, Muhammad A / Schmidt, Rebecca J / Segal, Mark S / Tucker, J Kevin / Wiseman, Alexander C / Josephson, Michelle A

Clinical journal of the American Society of Nephrology : CJASN

2022 Volume 17, Issue 9, Page(s) 1403–1406

MeSH term(s)	Humans ; Kidney Transplantation/adverse effects ; Nephrology ; Kidney Failure, Chronic/surgery ; Nephrectomy
Language	English
Publishing date	2022-08-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	2226665-3
ISSN	1555-905X ; 1555-9041
ISSN (online)	1555-905X
ISSN	1555-9041
DOI	10.2215/CJN.02000222
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6584: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: A National Survey of Practice Patterns for Accepting Living Kidney Donors With Prior COVID-19.

Jan, Muhammad Y / Jawed, Areeba T / Barros, Nicolas / Adebiyi, Oluwafisayo / Diez, Alejandro / Fridell, Jonathan A / Goggins, William C / Yaqub, Muhammad S / Anderson, Melissa D / Mujtaba, Muhammad A / Taber, Tim E / Mishler, Dennis P / Kumar, Vineeta / Lentine, Krista L / Sharfuddin, Asif A

Kidney international reports

2021 Volume 6, Issue 8, Page(s) 2066–2074

Abstract: Introduction: A critical question facing transplant programs is whether, when, and how to safely accept living kidney donors (LKDs) who have recovered from COVID-19 infection. The purpose of the study is to understand current practices related to ... ...

Abstract	Introduction: A critical question facing transplant programs is whether, when, and how to safely accept living kidney donors (LKDs) who have recovered from COVID-19 infection. The purpose of the study is to understand current practices related to accepting these LKDs. Methods: We surveyed US transplant programs from 3 September through 3 November 2020. Center level and participant level responses were analyzed. Results: A total of 174 respondents from 115 unique centers responded, representing 59% of US LKD programs and 72.4% of 2019 and 72.5% of 2020 LKD volume (Organ Procurement and Transplantation Network-OPTN 2021). In all, 48.6% of responding centers had received inquiries from such LKDs, whereas 44.3% were currently evaluating. A total of 98 donors were in the evaluation phase, whereas 27.8% centers had approved 42 such donors to proceed with donation. A total of 50.8% of participants preferred to wait >3 months, and 91% would wait at least 1 month from onset of infection to LD surgery. The most common reason to exclude LDs was evidence of COVID-19-related AKI (59.8%) even if resolved, followed by COVID-19-related pneumonia (28.7%) and hospitalization (21.3%). The most common concern in accepting such donors was kidney health postdonation (59.2%), followed by risk of transmission to the recipient (55.7%), donor perioperative pulmonary risk (41.4%), and donor pulmonary risk in the future (29.9%). Conclusion: Practice patterns for acceptance of COVID-19-recovered LKDs showed considerable variability. Ongoing research and consensus building are needed to guide optimal practices to ensure safety of accepting such donors. Long-term close follow-up of such donors is warranted.
Language	English
Publishing date	2021-05-15
Publishing country	United States
Document type	Journal Article
ISSN	2468-0249
ISSN (online)	2468-0249
DOI	10.1016/j.ekir.2021.05.003
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Early Fatal Cutaneous Lower Extremity Angiosarcoma Associated with Deep Venous Thrombosis in a Renal Transplant Recipient.

Sher, Syed J / Mujtaba, Muhammad A / Yaqub, Muhammad S / Taber, Tim E / Mishler, Dennis P / Sharfuddin, Asif A

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation

2017 Volume 15, Issue 4, Page(s) 463–466

Abstract: Angiosarcomas are extremely rare malignant tumors of vascular origin. We describe a 63-year-old recipient after a kidney transplant who had an angiosarcoma in the lower extremity that presented after new-onset deep venous thrombosis and was not ... ...

Abstract	Angiosarcomas are extremely rare malignant tumors of vascular origin. We describe a 63-year-old recipient after a kidney transplant who had an angiosarcoma in the lower extremity that presented after new-onset deep venous thrombosis and was not associated with any fistula. There was rapid progression to metastasis and death. We reviewed the literature of this rare malignant tumor in kidney transplant patients.
Language	English
Publishing date	2017-08
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	2396778-X
ISSN	2146-8427 ; 1304-0855
ISSN (online)	2146-8427
ISSN	1304-0855
DOI	10.6002/ect.2014.0289
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6632: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Deceased donor organ procurement injuries in the United States.

Taber, Tim E / Neidlinger, Nikole A / Mujtaba, Muhammad A / Eidbo, Elling E / Cauwels, Roxane L / Hannan, Elizabeth M / Miller, Jennifer R / Paramesh, Anil S

World journal of transplantation

2016 Volume 6, Issue 2, Page(s) 423–428

Abstract: Aim: To determine the incidence of surgical injury during deceased donor organ procurements.: Methods: Organ damage was classified into three tiers, from 1-3, with the latter rendering the organ non-transplantable. For 12 consecutive months starting ... ...

Abstract	Aim: To determine the incidence of surgical injury during deceased donor organ procurements. Methods: Organ damage was classified into three tiers, from 1-3, with the latter rendering the organ non-transplantable. For 12 consecutive months starting in January of 2014, 36 of 58 organ procurement organization's (OPO)'s prospectively submitted quality data regarding organ damage (as reported by the transplanting surgeon and confirmed by the OPO medical director) seen on the procured organ. Results: These 36 OPOs recovered 5401 of the nations's 8504 deceased donors for calendar year 2014. A total of 19043 organs procured were prospectively analyzed. Of this total, 59 organs sustained damage making them non-transplantable (0 intestines; 4 pancreata; 5 lungs; 6 livers; 43 kidneys). The class 3 damage was spread over 22 (of 36) reporting OPO's. Conclusion: While damage to the procured organ is rare with organ loss being approximately 0.3% of procured organs, loss of potential transplantable organs does occur during procurement.
Language	English
Publishing date	2016-05-27
Publishing country	United States
Document type	Journal Article
ISSN	2220-3230
ISSN	2220-3230
DOI	10.5500/wjt.v6.i2.423
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Trends and outcomes in right vs. left living donor nephrectomy: an analysis of the OPTN/UNOS database of donor and recipient outcomes--should we be doing more right-sided nephrectomies?

Khalil, Ali / Mujtaba, Muhammad A / Taber, Tim E / Yaqub, Muhammad S / Goggins, William / Powelson, John / Sundaram, Chandru / Sharfuddin, Asif A

Clinical transplantation

2016 Volume 30, Issue 2, Page(s) 145–153

Abstract: Background: Discussion continues about right vs. left donor nephrectomy (LDN). Left side is preferred due to longer renal vein while right side has been associated with renal vein thrombosis and shorter vessels.: Methods: A retrospective analysis of ... ...

Abstract	Background: Discussion continues about right vs. left donor nephrectomy (LDN). Left side is preferred due to longer renal vein while right side has been associated with renal vein thrombosis and shorter vessels. Methods: A retrospective analysis of UNOS database for adult living donor transplants between 1 January 2000 and 31 December 2009. Results: We identified 58 599 living donor transplants, of which 86.1% were LDN. There were no significant differences between the recipients or donors demographics. There were higher rates of delayed graft function in right donor nephrectomy (RDN) recipients with a hazard risk of 1.38 (95% CI 1.24-1.53; p < 0.0001). Primary failure rates were similar. In the RDN group, graft thrombosis as cause of graft failure was statistically higher with a hazard ratio of 1.48 (95% CI 1.18-1.86, p = 0.0004), and graft survival was significantly inferior (p = 0.006 log-rank test). For living donors outcomes, the conversion from laparoscopic to open was higher in the RDN group with an odds ratio of 2.02 (95% CI 1.61-2.52; p < 0.00001). There was no significant difference in vascular complications or re-operation required due to bleeding. Re-operations and re-admissions were higher in the LDN group. Conclusion: There are statistical differences between left and right kidney donor nephrectomies on recipient outcomes, but the difference is extremely small. The choice and laterality should be based on center and surgeon preference and experience.
MeSH term(s)	Adult ; Delayed Graft Function/epidemiology ; Donor Selection ; Female ; Follow-Up Studies ; Glomerular Filtration Rate ; Graft Rejection/epidemiology ; Graft Survival ; Humans ; Incidence ; Indiana/epidemiology ; Kidney/blood supply ; Kidney/physiopathology ; Kidney Failure, Chronic/surgery ; Kidney Function Tests ; Kidney Transplantation/mortality ; Living Donors ; Male ; Nephrectomy/mortality ; Postoperative Complications ; Prognosis ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Survival Rate ; Tissue and Organ Harvesting/methods ; Transplant Donor Site/surgery
Language	English
Publishing date	2016-02
Publishing country	Denmark
Document type	Comparative Study ; Journal Article
ZDB-ID	639001-8
ISSN	1399-0012 ; 0902-0063
ISSN (online)	1399-0012
ISSN	0902-0063
DOI	10.1111/ctr.12668
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 2204: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

To top

Your last searches

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito