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  1. Article ; Online: Subtractive proteomics to identify targets for vaccine development against vancomycin-resistant

    Imtiaz, Syed Asad / Saeed, Sania / Munir, Samman / Ashfaq, Usman Ali

    Future microbiology

    2021  

    Abstract: Aim: ...

    Abstract Aim:
    Language English
    Publishing date 2021-01-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2254620-0
    ISSN 1746-0921 ; 1746-0913
    ISSN (online) 1746-0921
    ISSN 1746-0913
    DOI 10.2217/fmb-2019-0341
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Exploring the Antimicrobial and Pharmacological Potential of NF22 as a Potent Inhibitor of

    Munir, Samman / Khurshid, Mohsin / Ahmad, Matloob / Ashfaq, Usman Ali / Zaki, Magdi E A

    Pharmaceutics

    2022  Volume 14, Issue 12

    Abstract: Toward the search for novel antimicrobial agents to control ... ...

    Abstract Toward the search for novel antimicrobial agents to control pathogenic
    Language English
    Publishing date 2022-12-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527217-2
    ISSN 1999-4923
    ISSN 1999-4923
    DOI 10.3390/pharmaceutics14122768
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: In Silico Subtractive Proteomics Approach for Identification of Potential Drug Targets in

    Shahid, Farah / Ashfaq, Usman Ali / Saeed, Sania / Munir, Samman / Almatroudi, Ahmad / Khurshid, Mohsin

    International journal of environmental research and public health

    2020  Volume 17, Issue 10

    Abstract: Staphylococcus ... ...

    Abstract Staphylococcus saprophyticus
    MeSH term(s) Aged ; Computational Biology ; Female ; Humans ; Metabolic Networks and Pathways ; Pregnancy ; Proteomics ; Staphylococcal Infections/drug therapy ; Staphylococcus saprophyticus/drug effects ; Staphylococcus saprophyticus/genetics ; Urinary Tract Infections
    Language English
    Publishing date 2020-05-22
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1660-4601
    ISSN (online) 1660-4601
    DOI 10.3390/ijerph17103644
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Nanozymes for medical biotechnology and its potential applications in biosensing and nanotherapeutics

    Munir, Samman / Bilal, Muhammad / Khan, Abdul Arif / Khurshid, Mohsin / Rahman, Hazir / Rajoka, Muhammad Shahid Riaz / Shah, Asad Ali

    Biotechnology letters. 2020 Mar., v. 42, no. 3

    2020  

    Abstract: Recent past years have witnessed the development of several artificial enzymes, using different materials to mimic natural enzymes with respect to their structure and functions. The nanozymes are nanomaterials possessing similar characteristics to the ... ...

    Abstract Recent past years have witnessed the development of several artificial enzymes, using different materials to mimic natural enzymes with respect to their structure and functions. The nanozymes are nanomaterials possessing similar characteristics to the natural enzymes and have emerged recently as an innovative class of artificial enzymes. The nanozymes have got remarkable attention from the researchers and notable developments have been achieved owing to their unique properties compared with natural enzymes and classic artificial enzymes. In this regard, several nanomaterials have been scrutinized so far to mimic different natural enzymes for wider applications ranging from imaging, sensing, water treatment, pollutant removal, and therapeutics. The applications of nanozymes in biomedicine research are fast-growing and various nanozymes have been implicated in diagnostic medicine, targeted cancer therapy. Such abilities make them an appropriate alternative for the development of affordable, sustainable and safe diagnostic as well as therapeutic agents.
    Keywords biotechnology ; cancer therapy ; enzymes ; image analysis ; medicine ; nanomaterials ; neoplasms ; pollution control ; water treatment
    Language English
    Dates of publication 2020-03
    Size p. 357-373.
    Publishing place Springer Netherlands
    Document type Article
    Note Review
    ZDB-ID 423853-9
    ISSN 1573-6776 ; 0141-5492
    ISSN (online) 1573-6776
    ISSN 0141-5492
    DOI 10.1007/s10529-020-02795-3
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4564: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Proteome-Wide Mapping and Reverse Vaccinology Approaches to Design a Multi-Epitope Vaccine against

    Aldakheel, Fahad M / Abrar, Amna / Munir, Samman / Aslam, Sehar / Allemailem, Khaled S / Khurshid, Mohsin / Ashfaq, Usman Ali

    Vaccines

    2021  Volume 9, Issue 10

    Abstract: ... C. ... ...

    Abstract C. perfringens
    Language English
    Publishing date 2021-09-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines9101079
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Nanozymes for medical biotechnology and its potential applications in biosensing and nanotherapeutics.

    Munir, Samman / Shah, Asad Ali / Rahman, Hazir / Bilal, Muhammad / Rajoka, Muhammad Shahid Riaz / Khan, Abdul Arif / Khurshid, Mohsin

    Biotechnology letters

    2020  Volume 42, Issue 3, Page(s) 357–373

    Abstract: Recent past years have witnessed the development of several artificial enzymes, using different materials to mimic natural enzymes with respect to their structure and functions. The nanozymes are nanomaterials possessing similar characteristics to the ... ...

    Abstract Recent past years have witnessed the development of several artificial enzymes, using different materials to mimic natural enzymes with respect to their structure and functions. The nanozymes are nanomaterials possessing similar characteristics to the natural enzymes and have emerged recently as an innovative class of artificial enzymes. The nanozymes have got remarkable attention from the researchers and notable developments have been achieved owing to their unique properties compared with natural enzymes and classic artificial enzymes. In this regard, several nanomaterials have been scrutinized so far to mimic different natural enzymes for wider applications ranging from imaging, sensing, water treatment, pollutant removal, and therapeutics. The applications of nanozymes in biomedicine research are fast-growing and various nanozymes have been implicated in diagnostic medicine, targeted cancer therapy. Such abilities make them an appropriate alternative for the development of affordable, sustainable and safe diagnostic as well as therapeutic agents.
    MeSH term(s) Biomimetic Materials/chemistry ; Biosensing Techniques ; Enzymes/chemistry ; Nanostructures/chemistry
    Chemical Substances Enzymes
    Language English
    Publishing date 2020-01-16
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 423853-9
    ISSN 1573-6776 ; 0141-5492
    ISSN (online) 1573-6776
    ISSN 0141-5492
    DOI 10.1007/s10529-020-02795-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4564: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: The Therapeutic Prospects of Naturally Occurring and Synthetic Indole Alkaloids for Depression and Anxiety Disorders.

    Munir, Samman / Shahid, Aqsa / Aslam, Bilal / Ashfaq, Usman Ali / Akash, Muhammad Sajid Hamid / Ali, Muhammad Akhtar / Almatroudi, Ahmad / Allemailem, Khaled S / Rajoka, Muhammad Shahid Riaz / Khurshid, Mohsin

    Evidence-based complementary and alternative medicine : eCAM

    2020  Volume 2020, Page(s) 8836983

    Abstract: Depression and anxiety are the most common disorders among all age groups. Several antidepressant drugs including benzodiazepine, antidepressant tricyclics, azapirone, noradrenaline reuptake inhibitors, serotonin selective reuptake inhibitors, serotonin, ...

    Abstract Depression and anxiety are the most common disorders among all age groups. Several antidepressant drugs including benzodiazepine, antidepressant tricyclics, azapirone, noradrenaline reuptake inhibitors, serotonin selective reuptake inhibitors, serotonin, noradrenaline reuptake inhibitors, and monoamine oxidase inhibitors have been used to treat these psychiatric disorders. However, these antidepressants are generally synthetic agents and can cause a wide range of side effects. The potential efficacy of plant-derived alkaloids has been reviewed against various neurodegenerative diseases including Alzheimer's disease, Huntington disease, Parkinson's disease, schizophrenia, and epilepsy. However, data correlating the indole alkaloids and antidepressant activity are limited. Natural products, especially plants and the marine environment, are rich sources of potential new drugs. Plants possess a variety of indole alkaloids, and compounds that have an indole moiety are related to serotonin, which is a neurotransmitter that regulates brain function and cognition, which in turn alleviates anxiety, and ensures a good mood and happiness. The present review is a summary of the bioactive compounds from plants and marine sources that contain the indole moiety, which can serve as potent antidepressants. The prospects of naturally occurring as well as synthetic indole alkaloids for the amelioration of anxiety and depression-related disorders, structure-activity relationship, and their therapeutic prospects have been discussed.
    Language English
    Publishing date 2020-10-16
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2171158-6
    ISSN 1741-4288 ; 1741-427X
    ISSN (online) 1741-4288
    ISSN 1741-427X
    DOI 10.1155/2020/8836983
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5995: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Anti-angiogenesis Potential of Phytochemicals for the Therapeutic Management of Tumors.

    Munir, Samman / Shah, Asad A / Shahid, Muhammad / Ahmed, Muhammad S / Shahid, Aqsa / Rajoka, Muhammad S R / Akash, Muhammad S H / Akram, Muhammad / Khurshid, Mohsin

    Current pharmaceutical design

    2019  Volume 26, Issue 2, Page(s) 265–278

    Abstract: The role of angiogeneses during the growth and progression of tumors is well documented. Likewise, a balance is generally maintained between the cellular proliferation and the apoptosis, therefore, the tumors can persist for years in a dormant phase. ... ...

    Abstract The role of angiogeneses during the growth and progression of tumors is well documented. Likewise, a balance is generally maintained between the cellular proliferation and the apoptosis, therefore, the tumors can persist for years in a dormant phase. During the past few years, many hypotheses have been proposed relating to the importance of tumor angiogenesis for the development and spread of tumors and preventive or therapeutic capacity of angiogenesis inhibitors as a potential target for controlling the growth of cancerous tissue. The antiangiogenic based therapeutic approaches are considered as the most promising method for the control of tumors, as this therapeutic approach is less likely to attain the drug resistance. Further, the tumor vasculature is an important prognostic marker that can independently predict the pathological stages as well as the metastatic potential of tumors. Various biologically active phytochemicals have been extracted from the dietary sources and the plants that have engaged the scientist and pharmaceutical industries around the globe. The antioxidant, antiinflammatory, anti-proliferative and anti-angiogenic potential of these bioactive phytochemicals is evident from the in vitro studies using cell lines and investigations involving the animal models. The present review is focused on the promising role of anti-angiogenesis-based therapies for the management of tumors and the recent developments relating to the interplay of phytochemicals and angiogenesis for the suppression of tumor cells.
    MeSH term(s) Angiogenesis Inhibitors/pharmacology ; Angiogenesis Inhibitors/therapeutic use ; Animals ; Humans ; Neoplasms/drug therapy ; Neovascularization, Pathologic/drug therapy ; Phytochemicals/pharmacology ; Phytochemicals/therapeutic use
    Chemical Substances Angiogenesis Inhibitors ; Phytochemicals
    Language English
    Publishing date 2019-12-26
    Publishing country United Arab Emirates
    Document type Journal Article ; Review
    ZDB-ID 1304236-1
    ISSN 1873-4286 ; 1381-6128
    ISSN (online) 1873-4286
    ISSN 1381-6128
    DOI 10.2174/1381612826666191230142638
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4714: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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