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Article: Discursos interpretativos y prácticas deliberativas: Propuesta metodológica para formulación de políticas públicas sanitarias en Colombia.

Ortega-Bolaños, Jesús A / Alba-Muñoz, Margarita I

Revista de salud publica (Bogota, Colombia)

2018 Volume 19, Issue 3, Page(s) 386–392

Abstract: Objective: To propose public health policies in local governance scenarios through community participation; this requires recognizing the interaction of all social actors through argumentative approaches.: Methods: Considering a critical hermeneutic ... ...

Title translation	Interpretative speeches and deliberative practices: a methodological proposal for the formulation of public health policies in Colombia.
Abstract	Objective: To propose public health policies in local governance scenarios through community participation; this requires recognizing the interaction of all social actors through argumentative approaches. Methods: Considering a critical hermeneutic approach, an argumentative rhetorical method was used to conduct a political formulation from a socio-centric scenario, based on a dialogue of knowledge between the community and local institutions, which allowed to identify and understand relevant social problems in health, related with early childhood and family. Results: A comprehensive public policy was built in accordance with existing social health programs to intervene aspects referring to early childhood, childhood, adolescence and family. Solutions and their implementation arise from a participatory nucleus that reconciles institutional political interests and social needs of the local community. Conclusions: The argumentative approach in public policies recognizes the dialectical nucleus of politics by bringing the community closer to government entities through active citizen participation in processes of identification, implementation and execution of social policies.
MeSH term(s)	Adolescent ; Adolescent Health ; Child ; Child Health ; Colombia ; Community Participation ; Health Policy ; Humans ; Policy Making ; Politics ; Social Determinants of Health ; Speech
Language	Spanish
Publishing date	2018-08-13
Publishing country	Colombia
Document type	Journal Article
ZDB-ID	2060572-9
ISSN	0124-0064
ISSN	0124-0064
DOI	10.15446/rsap.v19n3.67269
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Endoscopic retrieval of multiple large sharp foreign bodies from the stomach. Testing the limits of endoscopy.

Ariza-Fernández, José Luis / Úbeda-Muñoz, Margarita / Redondo-Cerezo, Eduardo

Gastroenterologia y hepatologia

2017 Volume 40, Issue 2, Page(s) 95–96

Title translation	Extracción endoscópica de cuerpos extraños múltiples, grandes y cortantes. Transitando los límites de la endoscopia.
Language	Spanish
Publishing date	2017-02
Publishing country	Spain
Document type	Journal Article
ZDB-ID	632502-6
ISSN	0210-5705
ISSN	0210-5705
DOI	10.1016/j.gastrohep.2015.12.011
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Article: Ferric Carboxymaltose Improves the Quality of Life of Patients with Inflammatory Bowel Disease and Iron Deficiency without Anaemia.

Huguet, Jose María / Cortés, Xavier / Boscá-Watts, Marta Maia / Muñoz, Margarita / Maroto, Nuria / Iborra, Marisa / Hinojosa, Esther / Capilla, María / Asencio, Carmina / Amoros, Cirilo / Paredes, Jose María

Journal of clinical medicine

2022 Volume 11, Issue 10

Abstract: Background: Iron deficiency (ID) without anaemia is a common comorbidity associated with inflammatory bowel disease (IBD) that has a negative impact on health-related quality of life (HRQoL). Methods: This multicentre, prospective, observational study ... ...

Abstract	Background: Iron deficiency (ID) without anaemia is a common comorbidity associated with inflammatory bowel disease (IBD) that has a negative impact on health-related quality of life (HRQoL). Methods: This multicentre, prospective, observational study examined the response to, safety of and impact on HRQoL of a single 500 mg dose of intravenous ferric carboxymaltose (FCM) in patients with IBD and ID without anaemia. The diagnostic criteria for ID were low serum ferritin (<30 µg/L in the absence of inflammatory activity or <100 µg/L with inflammation) and transferrin saturation index (TSAT) < 16%. The effect on iron levels and HRQoL, according to the health status questionnaires SF-12v2 and EQ-5D, was evaluated 1 month after FCM infusion in an outpatient setting. Results: Of the 105 patients who received FCM, 98 patients completed the study. After 1 month, a single dose of FCM significantly increased serum ferritin, serum iron and TSAT. Importantly, patients reported fewer ID symptoms and problems on all EQ-5D dimensions. They also had higher EQ-5D visual analogue scale and SF-12v2 scores after treatment. FCM had similar clinical effects on men and women and on patients with Crohn’s disease (n = 66) and ulcerative colitis (n = 32). Conclusion: A single dose of FCM rapidly restored iron parameters and significantly improved patients’ symptoms and HRQoL at 1 month after treatment.
Language	English
Publishing date	2022-05-15
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm11102786
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Article: Expansion of endogenous T cells in CSF of pediatric CNS tumor patients undergoing locoregional delivery of IL13R〿2-targeting CAR T cells: an interim analysis.

Wang, Leo / Oill, Angela Taravella / Blanchard, M / Wu, Melody / Hibbard, Jonathan / Sepulveda, Sean / Peter, Lance / Kilpatrick, Julie / Munoz, Margarita / Stiller, Tracey / Shulkin, Noah / Wagner, Jamie / Dolatabadi, Ally / Nisis, Monica / Shepphird, Jennifer / Sanchez, Gabriela / Lingaraju, Chetan / Manchanda, Mishika / Natri, Heini /

Kouakanou, Léonce / Sun, Grace / Oliver-Cervantes, Cheryl / Georges, Joseph / Aftabizadeh, Maryam / Forman, Stephen / Priceman, Saul / Ressler, Julie / Arvanitis, Leonidas / Cotter, Jennifer / D'Apuzzo, Massimo / Tamrazi, Benita / Badie, Behnam / Davidson, Tom / Banovich, Nicholas / Brown, Christine

Research square

2023

Abstract: Outcomes for pediatric brain tumor patients remain poor, and there is optimism that chimeric antigen receptor (CAR) T cell therapy can improve prognosis. Here, we present interim results from the first six pediatric patients treated on an ongoing phase I ...

Abstract	Outcomes for pediatric brain tumor patients remain poor, and there is optimism that chimeric antigen receptor (CAR) T cell therapy can improve prognosis. Here, we present interim results from the first six pediatric patients treated on an ongoing phase I clinical trial (NCT04510051) of IL13BBζ-CAR T cells delivered weekly into the lateral cerebral ventricles, identifying clonal expansion of endogenous CAR-negative CD8
Language	English
Publishing date	2023-10-23
Publishing country	United States
Document type	Preprint
DOI	10.21203/rs.3.rs-3454977/v1
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Article: Underwater hybrid endoscopic submucosal dissection in a rectal polyp: a case report of a new application of "underwater endoscopy".

Rodríguez Sánchez, Joaquín / Úbeda Muñoz, Margarita / de la Santa Belda, Eva / Olivencia Palomar, Pilar / Olmedo Camacho, José

Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva

2017 Volume 110, Issue 1, Page(s) 62–64

Abstract: Background: Hybrid endoscopic submucosal dissection (ESD) has been described as an alternative to traditional ESD. This technique is less time consuming, but the en bloc resection rate is lower than in ESD. Similar to endoscopic mucosal resection, the ... ...

Abstract	Background: Hybrid endoscopic submucosal dissection (ESD) has been described as an alternative to traditional ESD. This technique is less time consuming, but the en bloc resection rate is lower than in ESD. Similar to endoscopic mucosal resection, the underwater technique could improve preliminary disadvantages of hybrid ESD. Case report: We attempted a mixture resection technique of Hybrid ESD with underwater endoscopic mucosal resection (EMR). Using this approach, an underwater hybrid ESD was successfully performed without adverse events on a 71 year old woman with a 20 mm adenoma. The histologic analysis identified a tubulovillious adenoma with high grade dysplasia and tumor free margins. Discussion: Underwater hybrid ESD could be an alternative to ESD. Moreover the modification of the "underwater method" provides a suitable way to overcome the technical drawbacks of the hybrid ESD.
MeSH term(s)	Adenoma/pathology ; Adenoma/surgery ; Aged ; Endoscopic Mucosal Resection/methods ; Female ; Humans ; Intestinal Polyps/pathology ; Intestinal Polyps/surgery ; Rectal Neoplasms/pathology ; Rectal Neoplasms/surgery ; Treatment Outcome
Language	English
Publishing date	2017-11-22
Publishing country	Spain
Document type	Case Reports ; Journal Article
ZDB-ID	1070381-0
ISSN	1130-0108 ; 0212-7512
ISSN	1130-0108 ; 0212-7512
DOI	10.17235/reed.2017.5181/2017
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Article ; Online: Multiband mucosectomy for the treatment of challenging non-pedunculated colorectal polyps.

Rodríguez-Sánchez, Joaquín / De la Santa Belda, Eva / Olivencia Palomar, Pilar / Úbeda Muñoz, Margarita / Olmedo Camacho, José

Endoscopy

2017 Volume 50, Issue 3, Page(s) 253–258

Abstract: Background and study aims: Endoscopic mucosal resection is the gold standard treatment for non-pedunculated colorectal polyps; however, some specific situations (location behind folds, scarred or flat morphology) can make this technique challenging. We ... ...

Abstract	Background and study aims: Endoscopic mucosal resection is the gold standard treatment for non-pedunculated colorectal polyps; however, some specific situations (location behind folds, scarred or flat morphology) can make this technique challenging. We aimed to assess the efficacy and safety of multiband mucosectomy (MBM) for resection of non-pedunculated colorectal polyps. Patients and methods: This was a retrospective study of patients in whom MBM was performed to resect large non-pedunculated colorectal polyps. All procedures were carried out using the Shooter multiband ligator kit (Cook Medical, Limerick, Ireland). A 3-month follow-up colonoscopy was performed in all patients. Results: 10 patients underwent MBM for resection of 10 large (median 33.5 mm) non-pedunculated polyps. A total of 45 MBM sessions were carried out to resect all of the lesions using on average one rubber band per 1.5 cm Conclusions: In this small series of patients, MBM proved to be a safe and effective endoscopic resection technique for challenging non-pedunculated colorectal polyps.
MeSH term(s)	Aftercare/methods ; Aged ; Colon/pathology ; Colon/surgery ; Colonic Polyps/pathology ; Colonic Polyps/surgery ; Colonoscopy/methods ; Colonoscopy/statistics & numerical data ; Endoscopic Mucosal Resection/adverse effects ; Endoscopic Mucosal Resection/instrumentation ; Endoscopic Mucosal Resection/methods ; Female ; Humans ; Male ; Middle Aged ; Rectum/pathology ; Rectum/surgery ; Retrospective Studies ; Rubber Dams ; Spain ; Treatment Outcome
Language	English
Publishing date	2017-12-14
Publishing country	Germany
Document type	Journal Article
ZDB-ID	80120-3
ISSN	1438-8812 ; 0013-726X
ISSN (online)	1438-8812
ISSN	0013-726X
DOI	10.1055/s-0043-122387
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Article ; Online: BISAP, RANSON, lactate and others biomarkers in prediction of severe acute pancreatitis in a European cohort.

Valverde-López, Francisco / Matas-Cobos, Ana M / Alegría-Motte, Carlos / Jiménez-Rosales, Rita / Úbeda-Muñoz, Margarita / Redondo-Cerezo, Eduardo

Journal of gastroenterology and hepatology

2017 Volume 32, Issue 9, Page(s) 1649–1656

Abstract: Background and aim: The study aims to assess and compare the predicting ability of some scores and biomarkers in acute pancreatitis.: Methods: We prospectively collected data from 269 patients diagnosed of acute pancreatitis, admitted to Virgen de ... ...

Abstract	Background and aim: The study aims to assess and compare the predicting ability of some scores and biomarkers in acute pancreatitis. Methods: We prospectively collected data from 269 patients diagnosed of acute pancreatitis, admitted to Virgen de las Nieves University Hospital between June 2010 and June 2012. Blood urea nitrogen (BUN), C-reactive protein, and creatinine were measured on admission and after 48 h, lactate and bedside index for severity acute pancreatitis (BISAP) only on admission and RANSON within the first 48 h. Definitions from 2012 Atlanta Classification were used. Area under the curve (AUC) was calculated for each scoring system for predicting severe acute pancreatitis (SAP), mortality, and intensive care unit (ICU) admission, obtaining optimal cut-off values from the receiver operating characteristic curves. Results: Eight (3%) patients died, 17 (6.3%) were classified as SAP, and 10 (3.7%) were admitted in ICU. BISAP was the best predictor on admission for SAP, mortality, and ICU admission with an AUC of 0.9 (95% CI 0.83-0.97); 0.97 (95% CI 0.95-0.99); and 0.89 (95% CI 0.79-0.99), respectively. After 48 h, BUN 48 h was the best predictor of SAP (AUC = 0.96 CI: 0.92-0.99); BUN 48 h and BISAP were the best predictors for mortality (AUC = 0.97 CI: 0.95-0.99) and creatinine 48 h for ICU admission (AUC = 0.96 CI: 0.92-0.99). Lactate showed an AUC of 0.79 (CI: 0.71-0.88), 0.87 (CI: 0.78-0.96), and 0.77 (CI: 0.67-0.87) for SAP, mortality, and ICU admission, respectively. All parameters were predictors for SAP, mortality, and ICU admission, but C-reactive protein on admission was only a significant predictor of SAP. Conclusion: Bedside index for severity acute pancreatitis is a good predictive system for SAP, mortality, and ICU admission, being useful for triaging patients for ICU management. Lactate could be useful for developing new scores.
Language	English
Publishing date	2017-09
Publishing country	Australia
Document type	Journal Article
ZDB-ID	632882-9
ISSN	1440-1746 ; 0815-9319
ISSN (online)	1440-1746
ISSN	0815-9319
DOI	10.1111/jgh.13763
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Article ; Online: Quantitative PCR and Digital PCR for Detection of

Acosta Soto, Lucrecia / Santísima-Trinidad, Ana Belén / Bornay-Llinares, Fernando Jorge / Martín González, Marcos / Pascual Valero, José Antonio / Ros Muñoz, Margarita

BioMed research international

2017 Volume 2017, Page(s) 7515409

Abstract: The reuse of reclaimed water from wastewater depuration is a widespread and necessary practice in many areas around the world and must be accompanied by adequate and continuous quality control. ...

Abstract	The reuse of reclaimed water from wastewater depuration is a widespread and necessary practice in many areas around the world and must be accompanied by adequate and continuous quality control.
MeSH term(s)	Animals ; Ascariasis/parasitology ; Ascaris lumbricoides/isolation & purification ; Ascaris lumbricoides/pathogenicity ; Eggs/parasitology ; Helminths/isolation & purification ; Helminths/parasitology ; Humans ; Parasite Egg Count ; Real-Time Polymerase Chain Reaction ; Wastewater/parasitology
Chemical Substances	Waste Water
Language	English
Publishing date	2017-03-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	2698540-8
ISSN	2314-6141 ; 2314-6133
ISSN (online)	2314-6141
ISSN	2314-6133
DOI	10.1155/2017/7515409
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Book: La Iglesia española contra Napoleón

Martínez Ruíz, Enrique / Gil Muñoz, Margarita

la guerra ideológica

2010

Institution	Catholic Church
Author's details	Enrique Martínez Ruiz y Margarita Gil Muñoz
Language	Spanish
Size	313 p, 23 cm
Publisher	Actas
Publishing place	San Sebastián de los Reyes
Document type	Book
ISBN	9788497391078 ; 8497391071
Database	Former special subject collection: coastal and deep sea fishing

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Article: Comparison of AIMS65, Glasgow-Blatchford score, and Rockall score in a European series of patients with upper gastrointestinal bleeding: performance when predicting in-hospital and delayed mortality.

Martínez-Cara, Juan G / Jiménez-Rosales, Rita / Úbeda-Muñoz, Margarita / de Hierro, Mercedes López / de Teresa, Javier / Redondo-Cerezo, Eduardo

United European gastroenterology journal

2016 Volume 4, Issue 3, Page(s) 371–379

Abstract: Objective: AIMS65 is a score designed to predict in-hospital mortality, length of stay, and costs of gastrointestinal bleeding. Our aims were to revalidate AIMS65 as predictor of inpatient mortality and to compare AIMS65's performance with that of ... ...

Abstract	Objective: AIMS65 is a score designed to predict in-hospital mortality, length of stay, and costs of gastrointestinal bleeding. Our aims were to revalidate AIMS65 as predictor of inpatient mortality and to compare AIMS65's performance with that of Glasgow-Blatchford (GBS) and Rockall scores (RS) with regard to mortality, and the secondary outcomes of a composite endpoint of severity, transfusion requirements, rebleeding, delayed (6-month) mortality, and length of stay. Methods: The study included 309 patients. Clinical and biochemical data, transfusion requirements, endoscopic, surgical, or radiological treatments, and outcomes for 6 months after admission were collected. Clinical outcomes were in-hospital mortality, delayed mortality, rebleeding, composite endpoint, blood transfusions, and length of stay. Results: In receiver-operating characteristic curve analyses, AIMS65, GBS, and RS were similar when predicting inpatient mortality (0.76 vs. 0.78 vs. 0.78). Regarding endoscopic intervention, AIMS65 and GBS were identical (0.62 vs. 0.62). AIMS65 was useless when predicting rebleeding compared to GBS or RS (0.56 vs. 0.70 vs. 0.71). GBS was better at predicting the need for transfusions. No patient with AIMS65 = 0, GBS ≤ 6, or RS ≤ 4 died. Considering the composite endpoint, an AIMS65 of 0 did not exclude high risk patients, but a GBS ≤ 1 or RS ≤ 2 did. The three scores were similar in predicting prolonged in-hospital stay. Delayed mortality was better predicted by AIMS65. Conclusion: AIMS65 is comparable to GBS and RS in essential endpoints such as inpatient mortality, the need for endoscopic intervention and length of stay. GBS is a better score predicting rebleeding and the need for transfusion, but AIMS65 shows a better performance predicting delayed mortality.
Language	English
Publishing date	2016-06
Publishing country	England
Document type	Journal Article
ISSN	2050-6406
ISSN	2050-6406
DOI	10.1177/2050640615604779
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