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  1. Article ; Online: Autoimmune autonomic neuropathies: time to look beyond autoimmune autonomic ganglionopathy.

    Muppidi, Srikanth

    Clinical autonomic research : official journal of the Clinical Autonomic Research Society

    2018  Volume 28, Issue 1, Page(s) 7–8

    MeSH term(s) Autonomic Nervous System ; Ganglia, Autonomic ; Humans
    Language English
    Publishing date 2018-01-05
    Publishing country Germany
    Document type Editorial ; Comment
    ZDB-ID 1080007-4
    ISSN 1619-1560 ; 0959-9851
    ISSN (online) 1619-1560
    ISSN 0959-9851
    DOI 10.1007/s10286-017-0496-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3270: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Autonomic function testing in multiple system atrophy: a prognostic biomarker? and other updates on recent autonomic research.

    Miglis, Mitchell G / Muppidi, Srikanth

    Clinical autonomic research : official journal of the Clinical Autonomic Research Society

    2022  Volume 32, Issue 4, Page(s) 219–221

    MeSH term(s) Autonomic Nervous System ; Autonomic Nervous System Diseases/diagnosis ; Biomarkers ; Humans ; Multiple System Atrophy/diagnosis ; Prognosis
    Chemical Substances Biomarkers
    Language English
    Publishing date 2022-07-30
    Publishing country Germany
    Document type Editorial ; Comment
    ZDB-ID 1080007-4
    ISSN 1619-1560 ; 0959-9851
    ISSN (online) 1619-1560
    ISSN 0959-9851
    DOI 10.1007/s10286-022-00883-0
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3270: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Outcome Measures in Myasthenia Gravis: Incorporation Into Clinical Practice.

    Muppidi, Srikanth

    Journal of clinical neuromuscular disease

    2017  Volume 18, Issue 3, Page(s) 135–146

    Abstract: The development of validated assessment tools for evaluating disease status and response to interventions in patients with myasthenia gravis (MG) has been driven by clinical studies of emerging MG therapies. However, only a small proportion of MG-focused ...

    Abstract The development of validated assessment tools for evaluating disease status and response to interventions in patients with myasthenia gravis (MG) has been driven by clinical studies of emerging MG therapies. However, only a small proportion of MG-focused neurology practices have adopted these assessment tools for routine clinical use. This article reviews the suitability of 5 assessment instruments for incorporation into clinical practice, which should be driven by their ability to contribute to improved patient outcomes, and to be implemented within practice personnel and resource constraints. It is recommended that assessments based on both physician-evaluated and patient-reported outcomes be selected, to adequately evaluate both point-in-time symptom load and functional impact of MG symptoms over time. Provider resource allocation and reimbursement issues may be the most significant roadblocks to successful ongoing use of these tools; to that end, the addition of regular assessments to MG standards of care is recommended.
    MeSH term(s) Activities of Daily Living ; Autoantibodies/blood ; Humans ; Myasthenia Gravis/blood ; Myasthenia Gravis/drug therapy ; Myasthenia Gravis/immunology ; Outcome Assessment (Health Care)/methods ; Quality of Life ; Surveys and Questionnaires ; Symptom Assessment
    Chemical Substances Autoantibodies
    Language English
    Publishing date 2017-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1454947-5
    ISSN 1537-1611 ; 1522-0443
    ISSN (online) 1537-1611
    ISSN 1522-0443
    DOI 10.1097/CND.0000000000000156
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    Zs.A 5293: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Towards more evidenced-based therapies for postural tachycardia syndrome and other updates on recent autonomic research.

    Miglis, Mitchell G / Muppidi, Srikanth

    Clinical autonomic research : official journal of the Clinical Autonomic Research Society

    2021  Volume 31, Issue 2, Page(s) 145–147

    MeSH term(s) Autonomic Nervous System ; Heart Rate ; Humans ; Postural Orthostatic Tachycardia Syndrome/drug therapy
    Language English
    Publishing date 2021-03-11
    Publishing country Germany
    Document type Editorial ; Comment
    ZDB-ID 1080007-4
    ISSN 1619-1560 ; 0959-9851
    ISSN (online) 1619-1560
    ISSN 0959-9851
    DOI 10.1007/s10286-021-00795-5
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    Zs.A 3270: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Utilization of APE2 and RITE2 scores in autoimmune encephalitis patients with seizures.

    Rafferty, Trevor / Koeppen-Babcock, Anna / Muppidi, Srikanth / Li, Yi / Le, Scheherazade

    Epilepsy & behavior : E&B

    2024  Volume 154, Page(s) 109737

    Abstract: Purpose: Immune-mediated seizures are rare but are increasingly recognized as an etiology of seizures resistant to anti-seizure medications (ASMs). Antibody Prevalence in Epilepsy 2 (APE2) and Response to Immunotherapy in Epilepsy 2 (RITE2) scores were ... ...

    Abstract Purpose: Immune-mediated seizures are rare but are increasingly recognized as an etiology of seizures resistant to anti-seizure medications (ASMs). Antibody Prevalence in Epilepsy 2 (APE2) and Response to Immunotherapy in Epilepsy 2 (RITE2) scores were developed recently to identify patients who may be seropositive for serum central nervous system (CNS) specific antibodies (Ab) and may benefit from immunotherapy (Dubey et al. 2018). The goal of this study was to apply APE2 and RITE2 scores to an independent cohort of patients with seizures secondary to autoimmune encephalitis (AE) and to further verify the sensitivity and specificity of the scores.
    Principal results: We conducted a retrospective study at Stanford University Hospital between 2008 and 2021 and included patients who had acute seizures and AE using diagnostic criteria from Graus (n = 34 definite AE, 10 probable AE, and 12 possible AE) (Graus et al. 2016). Patients were excluded if they did not have a serum Ab panel investigated or had alternate diagnoses (n = 55). APE2 and RITE2 scores were calculated based on clinical and diagnostic data (n = 56). Serum Ab were positive in 73 % of patients, in which 63 % cases carried CNS specific Ab. An APE2 score ≥ 4 had a sensitivity of 97 % and specificity of 14 % to predict a positive serum CNS specific Ab. A RITE2 score ≥ 7 had a sensitivity of 93 % and specificity of 60 % to predict seizure responsiveness to immunotherapy.
    Conclusion: APE2 and RITE2 scores had high sensitivities but low specificities to predict seropositivity and seizure responsiveness to immunotherapy in patients with autoimmune encephalitis with seizures.
    MeSH term(s) Humans ; Female ; Male ; Adult ; Seizures/blood ; Seizures/etiology ; Seizures/diagnosis ; Middle Aged ; Retrospective Studies ; Encephalitis/complications ; Encephalitis/blood ; Encephalitis/immunology ; Encephalitis/diagnosis ; Hashimoto Disease/complications ; Hashimoto Disease/blood ; Aged ; Sensitivity and Specificity ; Autoantibodies/blood ; Young Adult ; Immunotherapy/methods ; Adolescent
    Chemical Substances Autoantibodies
    Language English
    Publishing date 2024-03-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2010587-3
    ISSN 1525-5069 ; 1525-5050
    ISSN (online) 1525-5069
    ISSN 1525-5050
    DOI 10.1016/j.yebeh.2024.109737
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    Zs.A 5289: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Neonatal Fc receptor blockade as emerging therapy in diseases with plasma exchange indications.

    Yunce, Muharrem / Katyal, Nakul / Monis, Grace Fortes / Muppidi, Srikanth

    Journal of clinical apheresis

    2023  Volume 38, Issue 5, Page(s) 632–640

    Abstract: Neonatal Fc receptor (FcRn) blockade may represent a mechanism similar to plasma exchange (PLEX) in reducing immunoglobulin levels and thus have a broad implication for apheresis practitioners. Although only efgartigimod received FDA approval for ... ...

    Abstract Neonatal Fc receptor (FcRn) blockade may represent a mechanism similar to plasma exchange (PLEX) in reducing immunoglobulin levels and thus have a broad implication for apheresis practitioners. Although only efgartigimod received FDA approval for myasthenia gravis in December 2021, multiple trials are currently underway with different FcRn therapies in a varied group of IgG antibody-mediated neurological and hematological disorders which are outlined in this review. In this review we discuss FcRn's mechanism of action, and its potential use in various neurological and non-neurological diseases. In addition, we further compare the kinetics and adverse events of PLEX and FcRn blockade. We encourage apheresis practitioners to be familiar with this class of drugs in order to better understand how these two therapies can be used either standalone, or in combination with other therapies as both FcRn antagonism and PLEX improve clinical state by reducing IgG levels and pathogenic antibodies.
    Language English
    Publishing date 2023-05-15
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 604912-6
    ISSN 1098-1101 ; 0733-2459
    ISSN (online) 1098-1101
    ISSN 0733-2459
    DOI 10.1002/jca.22055
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    Zs.A 1831: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Inappropriate sinus tachycardia in long-COVID and other updates on recent autonomic research.

    Miglis, Mitchell G / Larsen, Nicholas / Muppidi, Srikanth

    Clinical autonomic research : official journal of the Clinical Autonomic Research Society

    2022  Volume 32, Issue 2, Page(s) 91–94

    MeSH term(s) Autonomic Nervous System ; COVID-19/complications ; Humans ; Tachycardia, Sinus/diagnosis
    Language English
    Publishing date 2022-02-07
    Publishing country Germany
    Document type Editorial ; Comment
    ZDB-ID 1080007-4
    ISSN 1619-1560 ; 0959-9851
    ISSN (online) 1619-1560
    ISSN 0959-9851
    DOI 10.1007/s10286-022-00854-5
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3270: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Implantable neurostimulators for neurogenic orthostatic hypotension: the wave of the future? and other updates on recent autonomic research.

    Miglis, Mitchell G / Larsen, Nicholas / Muppidi, Srikanth

    Clinical autonomic research : official journal of the Clinical Autonomic Research Society

    2022  Volume 32, Issue 3, Page(s) 159–161

    MeSH term(s) Autonomic Nervous System ; Baroreflex ; Humans ; Hypotension, Orthostatic/diagnosis ; Implantable Neurostimulators
    Language English
    Publishing date 2022-06-03
    Publishing country Germany
    Document type Editorial ; Comment
    ZDB-ID 1080007-4
    ISSN 1619-1560 ; 0959-9851
    ISSN (online) 1619-1560
    ISSN 0959-9851
    DOI 10.1007/s10286-022-00871-4
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3270: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Mechanisms of post-prandial symptoms in postural tachycardia syndrome and other updates on recent autonomic research.

    Miglis, Mitchell G / Larsen, Nicholas / Muppidi, Srikanth

    Clinical autonomic research : official journal of the Clinical Autonomic Research Society

    2022  Volume 32, Issue 2, Page(s) 87–89

    MeSH term(s) Autonomic Nervous System ; Heart Rate ; Humans ; Postprandial Period ; Postural Orthostatic Tachycardia Syndrome/diagnosis
    Language English
    Publishing date 2022-03-22
    Publishing country Germany
    Document type Editorial
    ZDB-ID 1080007-4
    ISSN 1619-1560 ; 0959-9851
    ISSN (online) 1619-1560
    ISSN 0959-9851
    DOI 10.1007/s10286-022-00863-4
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3270: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  10. Article ; Online: Imaging in autonomic failure: a window into real-time physiological mechanisms and other updates on recent autonomic research.

    Miglis, Mitchell G / Larsen, Nicholas / Muppidi, Srikanth

    Clinical autonomic research : official journal of the Clinical Autonomic Research Society

    2022  Volume 32, Issue 6, Page(s) 405–407

    MeSH term(s) Humans ; Pure Autonomic Failure ; Autonomic Nervous System/diagnostic imaging
    Language English
    Publishing date 2022-11-21
    Publishing country Germany
    Document type Editorial
    ZDB-ID 1080007-4
    ISSN 1619-1560 ; 0959-9851
    ISSN (online) 1619-1560
    ISSN 0959-9851
    DOI 10.1007/s10286-022-00910-0
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    Zs.A 3270: Show issues Location:
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