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  1. Book ; Online ; E-Book: Biotribology of natural and artificial joints

    Murakami, Teruo

    reducing wear through material selection and geometric design with actual lubrication mode

    (Elsevier Series on Tribology and Surface Engineering)

    2023  

    Author's details Teruo Murakami
    Series title Elsevier Series on Tribology and Surface Engineering
    Keywords Artificial joints
    Subject code 060
    Language English
    Size 1 online resource (310 pages)
    Publisher Elsevier
    Publishing place Amsterdam, Netherlands
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 9780128236703 ; 9780128236697 ; 0128236701 ; 0128236698
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: Impacts and challenges for Japanese nuclear operators as a result of legislative change to extend the legal lifetime of nuclear power plants in Japan.

    Murakami, Tomoko

    Heliyon

    2024  Volume 10, Issue 3, Page(s) e25121

    Abstract: The purpose of nuclear regulation is not to impede the sound development of industry's competitiveness. Therefore, the regulations must be coherent, transparent and most of all, logical. On May 31st, 2023, a bill including rules to change the legal ... ...

    Abstract The purpose of nuclear regulation is not to impede the sound development of industry's competitiveness. Therefore, the regulations must be coherent, transparent and most of all, logical. On May 31st, 2023, a bill including rules to change the legal lifetime of nuclear power plants was approved and endorsed at the 211th ordinary session of the National Diet in Japan. An important characteristic of this legislative change is that it does not simply grant additional operating years to the original lifetime; rather, it considers the length of time that the plant was under shutdown status due to reasons not attributable to the plant owners and excludes this period from the countdown of the predetermined lifetime, thus extending the original legal lifetime. Three major problems could be listed in the procedures for changing the rules and in the new rules themselves. Firstly, the period during which this matter was discussed was too short to discuss issues raised by the change in detail. Secondly, the definitions of the period to be excluded from the predetermined lifetime are neither scientifically logical nor clear and would likely cause a great deal of confusion for both licensees and regulators when the new rule comes into effect. Thirdly, under this rule, the legal lifetime of a plant which performance is worse would be longer than that of the one with better operating performance. In particular, the second and the third problems deviate greatly from the purpose of nuclear regulation, which is not to impede the sound development of industry's competitiveness. The author strongly urges all parties involved to reconsider their decisions even after the bill has got an official approval at the National Diet.
    Language English
    Publishing date 2024-02-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e25121
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Editorial Comment: Hepatic Steatosis-Contrast-Enhanced CT Is a Leading Mark.

    Murakami, Takamichi

    AJR. American journal of roentgenology

    2023  Volume 221, Issue 6, Page(s) 759

    MeSH term(s) Humans ; Artificial Intelligence ; Fatty Liver/diagnostic imaging ; Tomography, X-Ray Computed
    Language English
    Publishing date 2023-07-26
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 82076-3
    ISSN 1546-3141 ; 0361-803X ; 0092-5381
    ISSN (online) 1546-3141
    ISSN 0361-803X ; 0092-5381
    DOI 10.2214/AJR.23.29953
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ue I Zs.57: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Central Blood Pressure Estimation.

    Murakami, Tomoaki

    Journal of atherosclerosis and thrombosis

    2023  Volume 30, Issue 9, Page(s) 1108–1110

    MeSH term(s) Humans ; Blood Pressure/physiology ; Blood Pressure Determination
    Language English
    Publishing date 2023-03-22
    Publishing country Japan
    Document type Editorial ; Comment
    ZDB-ID 2011474-6
    ISSN 1880-3873 ; 1340-3478
    ISSN (online) 1880-3873
    ISSN 1340-3478
    DOI 10.5551/jat.ED229
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5192: Show issues Location:
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  5. Article ; Online: Atherosclerosis and arteriosclerosis.

    Murakami, Tomoaki

    Hypertension research : official journal of the Japanese Society of Hypertension

    2023  Volume 46, Issue 7, Page(s) 1810–1811

    MeSH term(s) Humans ; Child ; Blood Pressure ; Pulse Wave Analysis ; Arteriosclerosis/physiopathology ; Atherosclerosis/physiopathology ; Dyslipidemias
    Language English
    Publishing date 2023-04-18
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 1175297-x
    ISSN 1348-4214 ; 0916-9636
    ISSN (online) 1348-4214
    ISSN 0916-9636
    DOI 10.1038/s41440-023-01284-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3898: Show issues Location:
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  6. Article ; Online: Isometric contraction induces transient increase of REDD1 expression in non-contracted muscles partly through glucocorticoids.

    Murakami, Taro

    Physiological reports

    2023  Volume 11, Issue 11, Page(s) e15745

    Abstract: This study investigated whether muscle contraction induces expression of regulated in development and DNA damage 1 (REDD1), a potent inhibitor of mTORC1, in mice muscle. Gastrocnemius muscle was unilaterally and isometrically contracted with electrical ... ...

    Abstract This study investigated whether muscle contraction induces expression of regulated in development and DNA damage 1 (REDD1), a potent inhibitor of mTORC1, in mice muscle. Gastrocnemius muscle was unilaterally and isometrically contracted with electrical stimulation, and changes in muscle protein synthesis, mTORC1 signaling phosphorylation, and REDD1 protein, and mRNA were measured at time points of 0, 3, 6, 12, and 24 h after the contraction. At time point 0 and 3 h, muscle protein synthesis was blunted by the contraction, accompanied by a decrease in phosphorylation of 4E-BP1 at time point 0 h, suggesting suppression of mTORC1 was involved in blunting of muscle protein synthesis during and shortly after the contraction. REDD1 protein was not increased in the contracted muscle at these time points, but at time point 3 h, both REDD1 protein and mRNA were increased in the contralateral non-contracted muscle. The induction of REDD1 expression in the non-contracted muscle was attenuated by RU-486, an antagonist of the glucocorticoid receptor, suggesting that glucocorticoids are involved in this process. These findings suggest that muscle contraction induces temporal anabolic resistance in non-contracted muscle, potentially increasing the availability of amino acids for contracted muscle, allowing for the synthesis of muscle protein.
    MeSH term(s) Mice ; Animals ; Glucocorticoids/pharmacology ; TOR Serine-Threonine Kinases/metabolism ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Isometric Contraction ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Muscle, Skeletal/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Phosphorylation/physiology ; Muscle Proteins/metabolism
    Chemical Substances Glucocorticoids ; TOR Serine-Threonine Kinases (EC 2.7.11.1) ; Transcription Factors ; Mechanistic Target of Rapamycin Complex 1 (EC 2.7.11.1) ; RNA, Messenger ; Muscle Proteins
    Language English
    Publishing date 2023-06-06
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2724325-4
    ISSN 2051-817X ; 2051-817X
    ISSN (online) 2051-817X
    ISSN 2051-817X
    DOI 10.14814/phy2.15745
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Aging in Patients With Fontan Circulation: Raison d'être of Right Ventricle.

    Murakami, Tomoaki

    Journal of the American College of Cardiology

    2023  Volume 83, Issue 12, Page(s) e117

    MeSH term(s) Humans ; Fontan Procedure/adverse effects ; Heart Ventricles/diagnostic imaging ; Aging
    Language English
    Publishing date 2023-09-27
    Publishing country United States
    Document type Letter
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2023.12.035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1846: Show issues Location:
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    Zs.MO 196: Show issues

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  8. Article: Vascular aging in adult congenital heart disease-a narrative review.

    Murakami, Tomoaki

    Cardiovascular diagnosis and therapy

    2022  Volume 12, Issue 4, Page(s) 521–530

    Abstract: Background and objective: Many studies about the high prevalence of cardiovascular disease in adults with congenital heart disease (CHD) have been published in response to the growing number of adult patients with CHD. The aging process leads to ... ...

    Abstract Background and objective: Many studies about the high prevalence of cardiovascular disease in adults with congenital heart disease (CHD) have been published in response to the growing number of adult patients with CHD. The aging process leads to hypertension and cardiovascular disease, which is caused by a degenerative change in the systemic arterial system characterized by the stiffening of elastic arteries (known as arteriosclerosis) and the enlargement of aorta. In patients with CHD, aortic dilatation (so-called aortopathy) is one of the most frequent complications. It is well known the anatomical and histological changes in aortopathy are similar to those in aging process. The increase of pulse wave velocity (PWV) enhances pressure wave reflection, and it augments left ventricular afterload and impairs the coronary supply-workload balance in aging. This article reviews the aortic function in patients with CHD, aiming to provide a new direction for the management of their cardiovascular aging process.
    Methods: Papers on vascular physiology in CHD were retrieved. I searched all original papers and reviews about the vascular physiology in CHD using PubMed, published from January 1, 1973 to June 30, 2022, in English.
    Key content and findings: Enhancement of pressure wave reflection has been reported in many CHDs. Although PWV in whole aorta is not necessarily elevated, the abnormal arterial stiffness gradient is common in patients with CHD.
    Conclusions: Many reports concerning functional abnormalities of the aorta have been reported. The abnormalities can result in cardiovascular disease and organ damage. The practitioners should carefully treat patients with CHD while paying attention to their aging process.
    Language English
    Publishing date 2022-08-01
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 2685043-6
    ISSN 2223-3660 ; 2223-3652
    ISSN (online) 2223-3660
    ISSN 2223-3652
    DOI 10.21037/cdt-22-218
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Rejuvenation of diabetic macular edema with senolytic therapy.

    Murakami, Tomoaki / Gardner, Thomas W

    Nature medicine

    2024  Volume 30, Issue 2, Page(s) 346–347

    MeSH term(s) Humans ; Macular Edema/drug therapy ; Diabetic Retinopathy/drug therapy ; Senotherapeutics ; Rejuvenation ; Vascular Endothelial Growth Factor A ; Diabetes Mellitus
    Chemical Substances Senotherapeutics ; Vascular Endothelial Growth Factor A
    Language English
    Publishing date 2024-02-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1220066-9
    ISSN 1546-170X ; 1078-8956
    ISSN (online) 1546-170X
    ISSN 1078-8956
    DOI 10.1038/s41591-024-02804-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4212: Show issues Location:
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    Zs.MG 39: Show issues

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  10. Article ; Online: OCT Angiography Image Stack Casts Light on Multifaceted Pathophysiologic Features in Diabetic Microaneurysms.

    Murakami, Tomoaki

    Ophthalmology. Retina

    2020  Volume 4, Issue 2, Page(s) 187–188

    MeSH term(s) Diabetes Mellitus ; Fluorescein Angiography ; Humans ; Microaneurysm ; Retinal Vessels ; Tomography, Optical Coherence
    Language English
    Publishing date 2020-02-04
    Publishing country United States
    Document type Editorial ; Comment
    ISSN 2468-7219
    ISSN (online) 2468-7219
    DOI 10.1016/j.oret.2019.10.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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