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Article ; Online: Ophthalmologic evaluation in infants of mothers with Zika: A report from Colombia.

Alvarado-Socarras, Jorge L / Aux-Cadena, Claudia Paola / Murillo-García, David R / Rodríguez-Morales, Alfonso J

2019 Volume 32, Page(s) 101449

Language	English
Publishing date	2019-07-09
Publishing country	Netherlands
Document type	Letter
ZDB-ID	2170891-5
ISSN	1873-0442 ; 1477-8939
ISSN (online)	1873-0442
ISSN	1477-8939
DOI	10.1016/j.tmaid.2019.07.005
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Article ; Online: Chikungunya in Bolivia: Still a Neglected Disease?

Escalera-Antezana, Juan Pablo / Murillo-García, David R / Rodriguez-Morales, Alfonso J

Archives of medical research

2018 Volume 49, Issue 4, Page(s) 288

MeSH term(s)	Arthralgia ; Bolivia ; Chikungunya Fever ; Cohort Studies ; Humans ; Neglected Diseases
Language	English
Publishing date	2018-09-27
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	1156844-6
ISSN	1873-5487 ; 0188-4409 ; 0188-0128
ISSN (online)	1873-5487
ISSN	0188-4409 ; 0188-0128
DOI	10.1016/j.arcmed.2018.09.002
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Article: Chikungunya in Bolivia: Domestic imported case series in Cochabamba.

Escalera-Antezana, Juan Pablo / Murillo-García, David R / Gómez, Christian / Unzueta-Quiroga, Roberto Carlos / Rodríguez-Morales, Alfonso J

Journal of the Formosan Medical Association = Taiwan yi zhi

2018 Volume 117, Issue 12, Page(s) 1133–1134

MeSH term(s)	Aedes ; Animals ; Bolivia ; Chikungunya virus ; Taiwan
Language	English
Publishing date	2018-10-30
Publishing country	Singapore
Document type	Letter ; Comment
ZDB-ID	2096659-3
ISSN	1876-0821 ; 0929-6646
ISSN (online)	1876-0821
ISSN	0929-6646
DOI	10.1016/j.jfma.2018.10.009
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Article: Paederus dermatitis - A bibliometric analysis of an emerging disease in travelers.

Osorio-Velásquez, Brahyan / García-Zuluaga, Luisa M / López-Bueno, Isaac / Soto-Vásquez, Jessica P / Vásquez-Castañeda, Danna L / Cortés-Bonilla, Isabella / Murillo-García, David R / Rodríguez-Morales, Alfonso J

Le infezioni in medicina

2020 Volume 28, Issue 1, Page(s) 130–132

Abstract: Not available. ...

Abstract	Not available.
MeSH term(s)	Animals ; Bibliometrics ; Coleoptera/chemistry ; Dermatitis, Allergic Contact/parasitology ; Humans ; Pyrans/toxicity ; Travel-Related Illness
Chemical Substances	Pyrans ; pederin (B8F7J348GJ)
Language	English
Publishing date	2020-04-11
Publishing country	Italy
Document type	Letter
ZDB-ID	2041081-5
ISSN	1124-9390
ISSN	1124-9390
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Article: Anaerobic Bacteremias in Left Ventricular Assist Devices and Advanced Heart Failure.

Murillo-Garcia, David R / Galindo, Julian / Pinto, Natalia / Motoa, Gabriel / Benamu, Esther / Franco-Paredes, Carlos / Chastain, Daniel B / Henao-Martínez, Andrés F

Case reports in infectious diseases

2019 Volume 2019, Page(s) 7571606

Abstract: Left ventricular assisted devices (LVADs) have revolutionized the treatment of advanced heart failure, providing meaningful increases in survival, functional capacity, and quality of life. There are two categories of LVADs patients: (1) bridge-to- ... ...

Abstract	Left ventricular assisted devices (LVADs) have revolutionized the treatment of advanced heart failure, providing meaningful increases in survival, functional capacity, and quality of life. There are two categories of LVADs patients: (1) bridge-to-transplant and (2) destination therapy. Advanced heart failure and destination LVADs often carry a poor prognosis. The overall 1-year mortality rate remains as high as 30%. LVAD-specific infections, LVAD-related infections, and non-LVAD-related infections represent important emerging clinical problems in this setting. With an incidence ranging from 30 to 50%, these lead to high rates of hospitalization, morbidity, and mortality. Bacteremias caused by anaerobic pathogens in patients with LVAD are underreported. Herein, we describe the microbiological findings, treatment, and clinical outcome of four patients with LVADs and advanced heart failure with anaerobic bacteremias.
Language	English
Publishing date	2019-12-19
Publishing country	Egypt
Document type	Case Reports
ZDB-ID	2627642-2
ISSN	2090-6633 ; 2090-6625
ISSN (online)	2090-6633
ISSN	2090-6625
DOI	10.1155/2019/7571606
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Article ; Online: Mitigation of the global impact of Lassa fever: Have we investigated enough about this Arenavirus? - A bibliometric analysis of Lassa Fever research.

Almeida-Guerrero, Alejandro / Olaya-Gómez, Juan C / Sánchez-Ramírez, Nicolás / Murillo-García, David R / Cardona-Ospina, Jaime A / Lagos-Grisales, Guillermo J / Rodríguez-Morales, Alfonso J

Travel medicine and infectious disease

2018 Volume 24, Page(s) 13–14

MeSH term(s)	Arenavirus ; Bibliometrics ; Humans ; Lassa Fever
Language	English
Publishing date	2018-07
Publishing country	Netherlands
Document type	Letter ; Comment
ZDB-ID	2170891-5
ISSN	1873-0442 ; 1477-8939
ISSN (online)	1873-0442
ISSN	1477-8939
DOI	10.1016/j.tmaid.2018.06.012
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Article ; Online: Susceptibility to endemic Aedes-borne viruses among pregnant women in Risaralda, Colombia.

Cardona-Ospina, Jaime A / Trujillo, Adriana M / Jiménez-Posada, Erika V / Sepúlveda-Arias, Juan C / Tabares-Villa, Fredy A / Altieri-Rivera, Joanne S / Monsalve, Alejandro / Restrepo-Chica, Juliana / Osorio, Daniela / Espinoza, Daniel / Zhu, Yerun / Castrillón-Spitia, Juan D / Henao-SanMartin, Valentina / Murillo-Garcia, David R / Millán, Natalia / Olaya, Sandra X / Valencia-Montoya, Ana M / Bedoya-Arias, Hugo A / Villamizar-Peña, Rhuvi /

Gutierrez-Ocampo, Estefanía / Holguin-Rivera, Yeimer / Cortés-Bonilla, Isabella / Cardona-Trujillo, Maria C / García-Barco, Alejandra / Bonilla-Aldana, D Katterine / Lagos-Grisales, Guillermo J / Rodríguez-Morales, Alfonso J / Collins, Matthew H

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

2022 Volume 122, Page(s) 832–840

Abstract: Objectives: Aedes-borne viruses (ABV) affect humans on every inhabited continent and frequently cause epidemics. Recent epidemics of chikungunya and Zika viruses (ZIKV) highlight that preparedness for future epidemics requires assessment of ... ...

Abstract	Objectives: Aedes-borne viruses (ABV) affect humans on every inhabited continent and frequently cause epidemics. Recent epidemics of chikungunya and Zika viruses (ZIKV) highlight that preparedness for future epidemics requires assessment of susceptibility, particularly among high-risk groups. We sought to determine immunity against the three major circulating ABV among pregnant women in an ABV-endemic area of Colombia. Methods: A cross-sectional seroprevalence study was performed, enrolling women presenting to Labor and Delivery. Cord blood and maternal peripheral blood samples were obtained. IgG seroprevalence to flaviviruses and chikungunya was determined by ELISA. An abbreviated neutralization test was used to estimate the frequency and magnitude of immunity to Zika and four dengue serotypes. Cluster analyses explored epidemiologic factors associated with seroprevalence. Results: Most women exhibited high levels of neutralizing antibodies to one or more ABV; however, nearly 20% were seronegative for flaviviruses. Our research took place after the epidemic peak of the ZIKV outbreak in Colombia in 2016. However, only 20% of pregnant women had high levels of Zika-neutralizing antibodies consistent with likely protective immunity to ZIKV. Conclusion: Hence, a high proportion of pregnant women in Risaralda remain susceptible to one or more ABV including the teratogenic ZIKV, indicating a risk for future epidemics in this region.
MeSH term(s)	Aedes ; Animals ; Antibodies, Neutralizing ; Antibodies, Viral ; Chikungunya Fever/epidemiology ; Colombia/epidemiology ; Cross-Sectional Studies ; Dengue/epidemiology ; Dengue Virus ; Female ; Humans ; Pregnancy ; Pregnant Women ; Seroepidemiologic Studies ; Zika Virus ; Zika Virus Infection
Chemical Substances	Antibodies, Neutralizing ; Antibodies, Viral
Language	English
Publishing date	2022-07-09
Publishing country	Canada
Document type	Journal Article
ZDB-ID	1331197-9
ISSN	1878-3511 ; 1201-9712
ISSN (online)	1878-3511
ISSN	1201-9712
DOI	10.1016/j.ijid.2022.07.017
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Article: Post-chikungunya chronic inflammatory rheumatism: results from a retrospective follow-up study of 283 adult and child cases in La Virginia, Risaralda, Colombia.

Rodriguez-Morales, Alfonso J / Gil-Restrepo, Andrés F / Ramírez-Jaramillo, Valeria / Montoya-Arias, Cindy P / Acevedo-Mendoza, Wilmer F / Bedoya-Arias, Juan E / Chica-Quintero, Laura A / Murillo-García, David R / García-Robledo, Juan E / Castrillón-Spitia, Juan D / Londoño, Jose J / Bedoya-Rendón, Hector D / Cárdenas-Pérez, Javier de Jesús / Cardona-Ospina, Jaime A / Lagos-Grisales, Guillermo J

F1000Research

2016 Volume 5, Page(s) 360

Abstract: Objective: There are limited studies in Latin America regarding the chronic consequences of the Chikungunya virus (CHIK), such as post-CHIK chronic inflammatory rheumatism (pCHIK-CIR). We assessed the largest cohort so far of pCHIK-CIR in Latin America, ...

Abstract	Objective: There are limited studies in Latin America regarding the chronic consequences of the Chikungunya virus (CHIK), such as post-CHIK chronic inflammatory rheumatism (pCHIK-CIR). We assessed the largest cohort so far of pCHIK-CIR in Latin America, at the municipality of La Virginia, Risaralda, a new endemic area of CHIK in Colombia. Methods: We conducted a cohort retrospective study in Colombia of 283 patients diagnosed with CHIK that persisted with pCHIK-CIR after a minimum of 6 weeks and up to a maximum of 26.1 weeks. pCHIK cases were identified according to validated criteria via telephone. Results: Of the total CHIK-infected subjects, 152 (53.7%) reported persistent rheumatological symptoms (pCHIK-CIR). All of these patients reported joint pains (chronic polyarthralgia, pCHIK-CPA), 49.5% morning stiffness, 40.6% joint edema, and 16.6% joint redness. Of all patients, 19.4% required and attended for care prior to the current study assessment (1.4% consulting rheumatologists). Significant differences in the frequency were observed according to age groups and gender. Patients aged >40 years old required more medical attention (39.5%) than those ≤40 years-old (12.1%) (RR=4.748, 95%CI 2.550-8.840). Conclusions: According to our results, at least half of the patients with CHIK developed chronic rheumatologic sequelae, and from those with pCHIK-CPA, nearly half presented clinical symptoms consistent with inflammatory forms of the disease. These results support previous estimates obtained from pooled data of studies in La Reunion (France) and India and are consistent with the results published previously from other Colombian cohorts in Venadillo (Tolima) and Since (Sucre).
Language	English
Publishing date	2016-03-16
Publishing country	England
Document type	Journal Article
ZDB-ID	2699932-8
ISSN	2046-1402
ISSN	2046-1402
DOI	10.12688/f1000research.8235.2
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Article ; Online: Diagnosis and outcomes of pregnant women with Zika virus infection in two municipalities of Risaralda, Colombia: Second report of the ZIKERNCOL study.

Rodriguez-Morales, Alfonso J / Cardona-Ospina, Jaime A / Ramirez-Jaramillo, Valeria / Gaviria, Javier A / González-Moreno, Gloria María / Castrillón-Spitia, Juan D / López-Villegas, Alejandra / Morales-Jiménez, Estefania / Ramírez-Zapata, Valentina / Rueda-Merchán, German Eduardo / Trujillo, Adriana M / Tabares-Villa, Fredy A / Henao-SanMartin, Valentina / Murillo-Garcia, David R / Herrera-Soto, Johana Andrea / Buitrago-Cañas, Marta Liliana / Collins, Matthew H / Sepúlveda-Arias, Juan Carlos / Londoño, José J /

Bedoya-Rendón, Héctor D / de Jesús Cárdenas-Pérez, Javier / Olaya, Sandra X / Lagos-Grisales, Guillermo J

Travel medicine and infectious disease

2018 Volume 25, Page(s) 20–25

Abstract: Background: Zika virus (ZIKV) infection has emerged as a significant threat for pregnant women and newborns in populations living in or visiting Latin America. We previously reported a preliminary analysis in Sucre, Colombia, as the first group of ... ...

Abstract	Background: Zika virus (ZIKV) infection has emerged as a significant threat for pregnant women and newborns in populations living in or visiting Latin America. We previously reported a preliminary analysis in Sucre, Colombia, as the first group of pregnant women with RT-PCR-confirmed ZIKV (ZIKa enEmbarazadas yReciénNacidos enCOLombia, ZIKERNCOL). Methods: In this second report, findings of the first 86 pregnant women from La Virginia and Dosquebradas (municipalities), Risaralda, Colombia, with RT-PCR-confirmed ZIKV infection are reported. Clinical, demographical and obstetrical findings are described. Results: All women reported ZIKV symptoms during pregnancy: 79.1% rash, 55.8% fever, among others. In addition to ZIKV, RT-PCR was positive for dengue in 18.6%; 45.3% Dengue IgM+; 5.8% RT-PCR positive for chikungunya; 3.6% Chikungunya IgM+. STORCH screening in mother: 11.6% IgG + anti-Toxoplasma gondii, 6% IgG + anti-rubella, 4.7% IgG + CMV. The rest of STORCH tests were negative. Microcephaly was observed in 2.4% of the newborns. No calcifications or other CNS alterations were detected. One newborn had cleft palate and one had bilateral renal ectopy. Conclusions: The rate of microcephaly in our cohort was consistent with other studies. Pregnant women in endemic areas should be followed and tested according to standard protocols, and asymptomatic ZIKV infection should be considered. Long-term follow-up of children is required in the congenital Zika syndrome (CZS) assessment.
MeSH term(s)	Adolescent ; Adult ; Antibodies, Viral ; Chikungunya Fever/immunology ; Cohort Studies ; Colombia/epidemiology ; Dengue/diagnosis ; Dengue/immunology ; Female ; Humans ; Immunoglobulin G ; Infant, Newborn ; Microcephaly/virology ; Pregnancy ; Pregnancy Complications, Infectious/virology ; Retrospective Studies ; Rubella/immunology ; Toxoplasmosis ; Young Adult ; Zika Virus Infection/diagnosis ; Zika Virus Infection/epidemiology
Chemical Substances	Antibodies, Viral ; Immunoglobulin G
Language	English
Publishing date	2018-06-09
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2170891-5
ISSN	1873-0442 ; 1477-8939
ISSN (online)	1873-0442
ISSN	1477-8939
DOI	10.1016/j.tmaid.2018.06.006
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Article: Zika virus and HIV co-infection in five patients from two areas of Colombia.

Villamil-Gómez, Wilmer E / Sánchez-Herrera, Álvaro Rosendo / Hernández-Prado, Hugo / Hernández-Iriarte, Jayder / Díaz-Ricardo, Kelly / Vergara-Serpa, Oscar / Castellanos, Jaime / Portela-Gaviria, Juan Esteban / Patiño-Valencia, Sarita / Vargas-Bedoya, Dana C / Orozco-Villa, Andrés F / Reyes-Guerrero, Sara S / Castrillón-Spitia, Juan Daniel / Murillo-García, David R / Henao-SanMartin, Valentina / Londoño, José J / Bedoya-Rendón, Héctor / de Jesús Cárdenas-Pérez, Javier / Cardona-Ospina, Jaime A /

Lagos-Grisales, Guillermo J / Rodríguez-Morales, Alfonso J

Journal of the Formosan Medical Association = Taiwan yi zhi

2018 Volume 117, Issue 9, Page(s) 856–858

MeSH term(s)	Coinfection ; Colombia ; HIV ; Humans ; Motivation ; Taiwan ; Zika Virus ; Zika Virus Infection
Language	English
Publishing date	2018-06-18
Publishing country	Singapore
Document type	Letter ; Comment
ZDB-ID	2096659-3
ISSN	1876-0821 ; 0929-6646
ISSN (online)	1876-0821
ISSN	0929-6646
DOI	10.1016/j.jfma.2018.05.019
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