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Article: Postoperative Textiloma Mimicking Intracranial Rebleeding in a Patient with Spontaneous Hemorrhage: Case Report and Review of the Literature.

Montemurro, Nicola / Murrone, Domenico / Romanelli, Bruno / Ierardi, Aldo

2020 Volume 12, Issue 1, Page(s) 7–12

Abstract: During craniotomy, hemostatic materials such as oxidized cellulose and cotton pads, commonly used to control bleeding, may cause a granulomatous reaction that may produce space-occupying mass lesions termed textiloma (or gossypiboma). We present a 46- ... ...

Abstract	During craniotomy, hemostatic materials such as oxidized cellulose and cotton pads, commonly used to control bleeding, may cause a granulomatous reaction that may produce space-occupying mass lesions termed textiloma (or gossypiboma). We present a 46-year-old female who underwent a right frontotemporal craniotomy and surgical removal of intraparenchymal cerebral hemorrhage, and who developed a textiloma during the postoperative period causing seizures. Granulomatous reactions due to hemostatic agents have been reported experimentally, as well as after cranial and spinal operations. We emphasize that although it is rare, an adverse reaction such as a postoperative textiloma due to hemostatic material and subsequent granuloma formation can result in a false image of rebleeding, tumor recurrence, radiation necrosis, or postoperative abscess, depending on the particular clinical history of each patient.
Language	English
Publishing date	2020-01-09
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2505302-4
ISSN	1662-680X
ISSN	1662-680X
DOI	10.1159/000505233
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Article ; Online: Minimally Invasive Transforaminal Interbody Fusion Versus Microdiscectomy Without Fusion for Recurrent Lumbar Disk Herniation: A Prospective Comparative Study.

D'Oria, Salvatore / Giraldi, David / Murrone, Domenico / Salamone, Giuseppe Giovanni / Tomatis, Alberto / Colamaria, Antonio / Carbone, Francesco / Rossitto, Martina / Fanelli, Vincenzo

The Journal of the American Academy of Orthopaedic Surgeons

2023 Volume 31, Issue 22, Page(s) 1157–1164

Abstract: Objective: The objective of this study was to compare the clinical outcome of minimally invasive transforaminal lumbar interbody fusion (MIS TLIF) versus standard revision diskectomy for recurrent lumbar disk herniation (RLDH).: Background: RLDH is ... ...

Abstract	Objective: The objective of this study was to compare the clinical outcome of minimally invasive transforaminal lumbar interbody fusion (MIS TLIF) versus standard revision diskectomy for recurrent lumbar disk herniation (RLDH). Background: RLDH is the most common cause of redo surgery after a microdiscectomy. Commonly, in patients without evidence of spinal instability, many surgeons would simply redo microdiscectomy, while others proceed to a redo microdiscectomy with arthrodesis. According to the literature, there is no evidence of what the best management of an RLDH would be. Methods: This study involved 90 patients who underwent lumbar microdiscectomy in the past and were now experiencing a new lumbar disk herniation for the first time. The patients were divided into two groups, each with 45 patients: group A received standard revision microdiscectomy, whereas group B received revision microdiscectomy with MIS TLIF.The Japanese Orthopaedic Association score, operating time, blood loss, duration of hospital stay, costs, and complications were all prospectively recorded in a database and examined. Back and leg discomfort were measured using the visual analog scale. Results: The mean total postoperative Japanese Orthopaedic Association score across the groups exhibited no statistically significant difference, nor did the preoperative clinical and epidemiological data. Although postoperative leg pain was comparable in both groups, postoperative lower back pain in group A was much worse than that in group B. Additional revision surgery was necessary for six individuals in group A. Group A had higher rates of dural rupture and postoperative neurological impairment. Group A experienced much less intraoperative blood loss, longer operation times, and postoperative hospital stays. Conclusion: In patients with RLDH, revision microdiscectomy is effective. In comparison with conventional microdiscectomy, MIS TLIF reduces intraoperative risk of dural rupture or neural injury, postoperative incidence of mechanical instability or recurrence, and postoperative lower back pain. Study design: Prospective, randomized, multicenter, comparative study.
MeSH term(s)	Humans ; Diskectomy ; Intervertebral Disc Displacement/surgery ; Low Back Pain/surgery ; Lumbar Vertebrae/surgery ; Minimally Invasive Surgical Procedures ; Pain, Postoperative ; Prospective Studies ; Retrospective Studies ; Spinal Fusion ; Treatment Outcome
Language	English
Publishing date	2023-08-08
Publishing country	United States
Document type	Journal Article ; Multicenter Study ; Randomized Controlled Trial
ZDB-ID	1200524-1
ISSN	1940-5480 ; 1067-151X
ISSN (online)	1940-5480
ISSN	1067-151X
DOI	10.5435/JAAOS-D-23-00123
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Zs.A 4048: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article: Postural instability after lumbar spinal surgery: are there any predictive factors? A case control study.

Chirchiglia, Domenico / Chirchiglia, Pasquale / Murrone, Domenico

Chinese neurosurgical journal

2018 Volume 4, Page(s) 40

Abstract: Background: The surgical spinal degenerative pathology mainly concerns the herniated intervertebral disks. Surgery is indicated when the pain becomes chronic and intense, and when motor signs appear. The results are positive in about 90% of cases, ... ...

Abstract	Background: The surgical spinal degenerative pathology mainly concerns the herniated intervertebral disks. Surgery is indicated when the pain becomes chronic and intense, and when motor signs appear. The results are positive in about 90% of cases, leading to the solution of the problem. However, an estimated percentage of 4% to 20% reported residual pain and postural instability after the surgical treatment of discectomy. Method: We have examined a sample of patients, retrospectively registered, undergoing surgical treatment for degenerative lumbar disease. Some of them developed postural instability. They were subjected to cycles of postural gymnastics. Postural gymnastics has proved to be a tool capable of solving unstable post-surgical posture. It included an exercise of breathing, one or two of muscular distension, one of muscular reinforcement, and one of postural correction. We used an evaluation form we created in agreement with the physiatrist for postural exercises that was based on some basic parameters such as muscle and respiratory function. At each cycle, a score was attributed to the performance of muscular and respiratory exercise to evaluate the function and therefore the degree of instability (1-3 = mild, 4-7 = medium, 8-10 = severe). Results: Results were satisfactory, with return to normal posture. The improvement of postural instability has been demonstrated both by the score of the evaluation forms that have highlighted the transition from a state of severe intensity to one of normality and by a clinical aspect, concerning the static and dynamic posture. Conclusions: The postural instability has a multifactorial genesis, and different mechanisms are involved: the vertebral bone structures and the pelvis, the paraspinal muscular structures, and the nerve structures. These structures are altered after surgery due to predisposing factors, and for the action of conditions acquired as obesity.
Language	English
Publishing date	2018-12-11
Publishing country	England
Document type	Journal Article
ISSN	2095-9370
ISSN	2095-9370
DOI	10.1186/s41016-018-0147-2
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Article ; Online: Clinical-neurophysiological-neuroradiological discordance in lumbar degenerative disc disease: should the neurosurgeon have the last word?

Chirchiglia, Domenico / Chirchiglia, Pasquale / Murrone, Domenico / Signorelli, Francesco

Journal of neurosurgical sciences

2018 Volume 64, Issue 3, Page(s) 307–308

MeSH term(s)	Adult ; Electromyography ; Female ; Humans ; Intervertebral Disc Degeneration/diagnostic imaging ; Intervertebral Disc Degeneration/surgery ; Low Back Pain/surgery ; Lumbar Vertebrae/diagnostic imaging ; Lumbar Vertebrae/surgery ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Neurosurgeons ; Neurosurgical Procedures/methods ; Radiculopathy/etiology ; Tomography, X-Ray Computed
Language	English
Publishing date	2018-06-14
Publishing country	Italy
Document type	Journal Article
ZDB-ID	193139-8
ISSN	1827-1855 ; 0390-5616 ; 0026-4881
ISSN (online)	1827-1855
ISSN	0390-5616 ; 0026-4881
DOI	10.23736/S0390-5616.18.04508-3
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Article: Sporadic hemangioblastoma of cauda equina: A case report and brief literature review.

D' Oria, Salvatore / Giraldi, David / Flores, Daniel Andres Alvarado / Murrone, Domenico / D' Angelo, Vincenzo / Chaurasia, Bipin

Journal of craniovertebral junction & spine

2022 Volume 13, Issue 3, Page(s) 265–270

Abstract: Background: Hemangioblastomas (HBs) are rare lesions accounting for 1%-5% of all spinal cord tumors, and are mostly associated with Von Hippel-Lindau (VHL) syndrome. Localization in the cauda equina is uncommon.: Aim: In this manuscript, we aimed to ... ...

Abstract	Background: Hemangioblastomas (HBs) are rare lesions accounting for 1%-5% of all spinal cord tumors, and are mostly associated with Von Hippel-Lindau (VHL) syndrome. Localization in the cauda equina is uncommon. Aim: In this manuscript, we aimed to describe a rare case of sporadic intradural extramedullary HB of the cauda equina and present a literature review. Mathods: A systematic research was performed on PubMed, MEDLINE, and Google Scholar, using the keywords "spinal HB" and "cauda equina tumors." The previous literature is integrated by the description of the present case. A 49-year-old female presented in August 2020 to our institution with a magnetic resonance imaging (MRI) which showed an intradural mass at L1/2 level and angiography that showing a nidus of serpiginous vessels inside the lesion. Symptoms were right sciatica and paresthesia in right L5 radicular dermatome for more than 3 months. Neurological examination revealed claudicatio spinalis and hypoesthesia on right L5 dermatome and weakness of right anterior tibialis muscle. Microsurgical en bloc resection of lesion was performed with adjuvant neurophysiological intraoperative monitoring. The histological examination provided the diagnosis of HB. Results: After surgery, symptoms and neurological impairment gradually improved. Postoperative MRI showed no residual tumor. Conclusions: Although intradural extramedullary HB of the cauda equina without VHL syndrome is a rare pathological entity, this diagnosis must be taken in consideration when a mass affects cauda equina. Preoperative embolization is an option to minimize intraoperative bleeding. Radiosurgery seems to prevent recurrences when the tumor is not completely excised. A complete surgical removal of the lesion is usually possible and it leads to a low likelihood of recurrence.
Language	English
Publishing date	2022-09-14
Publishing country	India
Document type	Journal Article ; Review
ZDB-ID	2573344-8
ISSN	0976-9285 ; 0974-8237
ISSN (online)	0976-9285
ISSN	0974-8237
DOI	10.4103/jcvjs.jcvjs_87_22
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Article: Acute onset of paraganglioma of filum terminale: A case report and surgical treatment.

Murrone, Domenico / Romanelli, Bruno / Vella, Giuseppe / Ierardi, Aldo

International journal of surgery case reports

2017 Volume 36, Page(s) 126–129

Abstract: Introduction: Paragangliomas of filum terminale are rare benign tumors, arising from the adrenal medulla or extra-adrenal paraganglia. These lesions usually present with chronic back pain and radiculopathy and only two cases of acute neurological ... ...

Abstract	Introduction: Paragangliomas of filum terminale are rare benign tumors, arising from the adrenal medulla or extra-adrenal paraganglia. These lesions usually present with chronic back pain and radiculopathy and only two cases of acute neurological deficit have been reported in literature. Presentation of case: A case with an acute paraplegia and cauda equina syndrome due to an hemorrhagic paraganglioma of the filum terminale is described. Magnetic resonance imaging showed an intradural tumor extending from L1 to L2 compressing the cauda equina, with an intralesional and intradural bleed. An emergent laminectomy with total removal of the tumor was performed allowing a post-operative partial sensory recovery. Histopathological examination diagnosed paraganglioma. Discussion: Paragangliomas are solid, slow growing tumors arising from specialized neural crest cells, mostly occurring in the head and neck and rarely in cauda equina or filum terminale. MRI is gold standard radiological for diagnosis and follow-up of these lesions. They have no pathognomonic radiological and clinical features and are frequently misdiagnosed as other spinal lesions. No significant correlation was observed between the duration of symptoms and tumor dimension. Acute presentation is unusual and emergent surgical treatment is fondamental. The outcome is very good after complete excision and radiotherapical treatment is recommended after an incomplete resection. Conclusion: Early radiological assessment and timely surgery are mandatory to avoid progressive neurological deficits in case of acute clinical manifestation of paraganglioma of filum terminale.
Language	English
Publishing date	2017-05-19
Publishing country	Netherlands
Document type	Journal Article
ISSN	2210-2612
ISSN	2210-2612
DOI	10.1016/j.ijscr.2017.05.016
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Article: Surgical case series of multiple aneurysms: A single-centre experience of 16 years.

Murrone, Domenico / Romanelli, Bruno / Ierardi, Aldo

International journal of surgery case reports

2017 Volume 42, Page(s) 191–195

Abstract: Introduction: Multiple aneurysms are present in 10% in patients with intracranial aneurysms. An analysis of the literature, focusing on the different treatments, and a description of our experience are performed.: Presentation of case series: A ... ...

Abstract	Introduction: Multiple aneurysms are present in 10% in patients with intracranial aneurysms. An analysis of the literature, focusing on the different treatments, and a description of our experience are performed. Presentation of case series: A surgical series with multiple intracranial aneurysms from 2000 to 2016, describing demographic, radiological and clinical features, is showed. In all patients a pre- and post-operative angiography was performed and surgical treatment, based on accurate indications, provided good outcomes in most cases. Discussion: Successful treatment of multiple intracranial aneurysms can be achieved by an interdisciplinary approach and the main factors influencing surgical treatment are discussed. Conclusions: Surgery always remains a definitive treatment and, considering intrinsic lesional features and patient's characteristics, it offers good results for intracranial multiple aneurysms.
Language	English
Publishing date	2017-12-15
Publishing country	Netherlands
Document type	Journal Article
ISSN	2210-2612
ISSN	2210-2612
DOI	10.1016/j.ijscr.2017.12.011
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Article ; Online: Ogilvie's Syndrome following spinal surgery.

Chirchiglia, Domenico / Chirchiglia, Pasquale / Vescio, Giuseppina / Murrone, Domenico

Journal of neurosurgical sciences

2017 Volume 63, Issue 5, Page(s) 612–613

MeSH term(s)	Colonic Pseudo-Obstruction/diagnosis ; Colonic Pseudo-Obstruction/surgery ; Female ; Humans ; Middle Aged ; Neurosurgical Procedures ; Postoperative Complications/diagnosis ; Postoperative Complications/etiology ; Postoperative Complications/surgery ; Spine/surgery ; Treatment Outcome
Language	English
Publishing date	2017-10-23
Publishing country	Italy
Document type	Case Reports ; Letter
ZDB-ID	193139-8
ISSN	1827-1855 ; 0390-5616 ; 0026-4881
ISSN (online)	1827-1855
ISSN	0390-5616 ; 0026-4881
DOI	10.23736/S0390-5616.17.04218-7
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Article: Falcine meningioma in Von Hippel-Lindau disease: An unusual association.

Murrone, Domenico / Romanelli, Bruno / Montemurro, Nicola / Chirchiglia, Domenico / Ierardi, Aldo

Surgical neurology international

2018 Volume 9, Page(s) 37

Abstract: Background: Von Hippel-Lindau (VHL) disease is an autosomal dominant condition characterized by formation of multiple benign and malignant tumors. In this disease supratentorial lesions are rare and no falcine meningioma has been previously reported. ... ...

Abstract	Background: Von Hippel-Lindau (VHL) disease is an autosomal dominant condition characterized by formation of multiple benign and malignant tumors. In this disease supratentorial lesions are rare and no falcine meningioma has been previously reported. Differential diagnosis is very difficult and the histopathological examination is the definitive method for diagnosis. Case description: A patient with VHL underwent a suboccipital craniotomy for removal of cerebellar hemangioblastoma and after 2 years magnetic resonance imaging (MRI) showed an iperintense solid mass located at posterior part of the falx. Histological diagnosis revealed meningioma. Conclusion: The only case in the literature of falcine meningioma in a patient with Von Hippel-Lindau disease, discovered during radiological follow-up, is described and a surgical management is proposed.
Language	English
Publishing date	2018-02-14
Publishing country	United States
Document type	Case Reports
ISSN	2229-5097
ISSN	2229-5097
DOI	10.4103/sni.sni_398_17
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Article: An unusual association of headache, epilepsy, and late-onset Kleist's pseudodepression syndrome in frontal lobe cavernoma of the cerebral left hemisphere.

Chirchiglia, Domenico / Della Torre, Attilio / Murrone, Domenico / Chirchiglia, Pasquale / Marotta, Rosa

International medical case reports journal

2017 Volume 10, Page(s) 163–166

Abstract: Cerebral cavernous angioma or cavernoma is a benign vascular malformation, usually asymptomatic. It is infrequent and often its discovery is incidental, a so-called incidentaloma. However, these lesions can be symptomatic, causing headaches, epilepsy, ... ...

Abstract	Cerebral cavernous angioma or cavernoma is a benign vascular malformation, usually asymptomatic. It is infrequent and often its discovery is incidental, a so-called incidentaloma. However, these lesions can be symptomatic, causing headaches, epilepsy, cerebral hemorrhage and other neurological signs depending on the brain area involved. Frontal localization is responsible for psychiatric disorders, particularly the prefrontal region, leading to prefrontal syndrome, a condition common in all frontal lobe tumors. Psychopathological syndrome can be depression-type, pseudodepression syndrome or maniac-type, pseudomaniac syndrome. Surgical treatment of lesions like this may not always be possible due to their location in eloquent areas. In this study, we describe an unusual association of migraine-like headache, epilepsy and frontal lobe pseudodepression late-onset syndrome in the same patient. We have considered this case interesting mainly for the rarity of both a headache with migraine features and for the late onset of pseudodepression syndrome. Pathophysiology underlying migraine-like headache and that concerning the late-onset pseudodepression frontal lobe syndrome seems to be unclear. This case leads to further hypotheses about the mechanisms responsible for headache syndromes and psychopathological disorders, in the specific case when caused by a cerebral frontal lobe lesion.
Language	English
Publishing date	2017-05-05
Publishing country	New Zealand
Document type	Case Reports
ZDB-ID	2495077-4
ISSN	1179-142X
ISSN	1179-142X
DOI	10.2147/IMCRJ.S133465
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