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  1. Article ; Online: Phylogenomic characterization and signs of microevolution in the 2022 multi-country outbreak of monkeypox virus.

    Isidro, Joana / Borges, Vítor / Pinto, Miguel / Sobral, Daniel / Santos, João Dourado / Nunes, Alexandra / Mixão, Verónica / Ferreira, Rita / Santos, Daniela / Duarte, Silvia / Vieira, Luís / Borrego, Maria José / Núncio, Sofia / de Carvalho, Isabel Lopes / Pelerito, Ana / Cordeiro, Rita / Gomes, João Paulo

    Nature medicine

    2022  Volume 28, Issue 8, Page(s) 1569–1572

    Abstract: The largest monkeypox virus (MPXV) outbreak described so far in non-endemic countries was identified in May 2022 (refs. ...

    Abstract The largest monkeypox virus (MPXV) outbreak described so far in non-endemic countries was identified in May 2022 (refs.
    MeSH term(s) Disease Outbreaks ; Humans ; Mpox (monkeypox)/epidemiology ; Mpox (monkeypox)/genetics ; Monkeypox virus/genetics ; Phylogeny
    Language English
    Publishing date 2022-06-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1220066-9
    ISSN 1546-170X ; 1078-8956
    ISSN (online) 1546-170X
    ISSN 1078-8956
    DOI 10.1038/s41591-022-01907-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Addendum: Phylogenomic characterization and signs of microevolution in the 2022 multi-country outbreak of monkeypox virus.

    Isidro, Joana / Borges, Vítor / Pinto, Miguel / Sobral, Daniel / Santos, João Dourado / Nunes, Alexandra / Mixão, Verónica / Ferreira, Rita / Santos, Daniela / Duarte, Silvia / Vieira, Luís / Borrego, Maria José / Núncio, Sofia / de Carvalho, Isabel Lopes / Pelerito, Ana / Cordeiro, Rita / Gomes, João Paulo

    Nature medicine

    2022  Volume 28, Issue 10, Page(s) 2220–2221

    MeSH term(s) Disease Outbreaks ; Monkeypox virus/genetics ; Phylogeny
    Language English
    Publishing date 2022-09-21
    Publishing country United States
    Document type Journal Article ; Published Erratum
    ZDB-ID 1220066-9
    ISSN 1546-170X ; 1078-8956
    ISSN (online) 1546-170X
    ISSN 1078-8956
    DOI 10.1038/s41591-022-02036-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Ongoing monkeypox virus outbreak, Portugal, 29 April to 23 May 2022.

    Perez Duque, Mariana / Ribeiro, Sofia / Martins, João Vieira / Casaca, Pedro / Leite, Pedro Pinto / Tavares, Margarida / Mansinho, Kamal / Duque, Luís Miguel / Fernandes, Cândida / Cordeiro, Rita / Borrego, Maria José / Pelerito, Ana / de Carvalho, Isabel Lopes / Núncio, Sofia / Manageiro, Vera / Minetti, Corrado / Machado, Jorge / Haussig, Joana M / Croci, Roberto /
    Spiteri, Gianfranco / Casal, Ana Sofia / Mendes, Diana / Souto, Tiago / Pocinho, Sara / Fernandes, Teresa / Firme, Ana / Vasconcelos, Paula / Freitas, Graça

    Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

    2022  Volume 27, Issue 22

    Abstract: Up to 27 May 2022, Portugal has detected 96 confirmed cases of monkeypox. We describe 27 confirmed cases (median age: 33 years (range: 22-51); all males), with an earliest symptom onset date of 29 April. Almost all cases (n = 25) live in the Lisbon and ... ...

    Abstract Up to 27 May 2022, Portugal has detected 96 confirmed cases of monkeypox. We describe 27 confirmed cases (median age: 33 years (range: 22-51); all males), with an earliest symptom onset date of 29 April. Almost all cases (n = 25) live in the Lisbon and Tagus Valley health region. Most cases were neither part of identified transmission chains, nor linked to travel or had contact with symptomatic persons or with animals, suggesting the possible previously undetected spread of monkeypox.
    MeSH term(s) Disease Outbreaks ; Humans ; Male ; Mpox (monkeypox)/diagnosis ; Mpox (monkeypox)/epidemiology ; Monkeypox virus/genetics ; Portugal/epidemiology ; Travel
    Language English
    Publishing date 2022-06-03
    Publishing country Sweden
    Document type Journal Article
    ZDB-ID 1338803-4
    ISSN 1560-7917 ; 1025-496X
    ISSN (online) 1560-7917
    ISSN 1025-496X
    DOI 10.2807/1560-7917.ES.2022.27.22.2200424
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The medical and veterinary role of Ornithodoros erraticus complex ticks (Acari: Ixodida) on the Iberian Peninsula.

    Boinas, Fernando / Ribeiro, Rita / Madeira, Sara / Palma, Mariana / de Carvalho, Isabel Lopes / Núncio, Sofia / Wilson, Anthony James

    Journal of vector ecology : journal of the Society for Vector Ecology

    2014  Volume 39, Issue 2, Page(s) 238–248

    Abstract: Argasid ticks of the Ornithodoros erraticus complex are associated with traditional pig-farming practices on the Iberian Peninsula and are also found elsewhere in North Africa, West Africa, and western Asia. The ticks associated with pig farming on the ... ...

    Abstract Argasid ticks of the Ornithodoros erraticus complex are associated with traditional pig-farming practices on the Iberian Peninsula and are also found elsewhere in North Africa, West Africa, and western Asia. The ticks associated with pig farming on the Iberian Peninsula are the only biological vectors of African swine fever virus (ASFV) known to occur in Europe, and their ecology makes them an extremely effective reservoir of both ASFV and the Borrelia species which cause tick-borne relapsing fever (TBRF) in humans. The recent reappearance of ASFV in the European Union, coupled with evidence that Portuguese tick populations continue to harbor Borrelia despite a lack of confirmed human infections, suggest that these populations merit closer attention. In Portugal, a series of surveys over the last twenty-five years indicates that the number of farm sites with tick infestations has declined and suggest that populations are sensitive to changes in farm management, particularly the use of modern pig housing. Various technologies have been suggested for the control of farm-associated Ornithodoros ticks and related species but, in our opinion, farm management changes are still the most effective strategy for population control. Furthermore, we suggest that this species could probably be eradicated from Iberian pig farms.
    MeSH term(s) African Swine Fever/prevention & control ; African Swine Fever/transmission ; African Swine Fever/virology ; African Swine Fever Virus/pathogenicity ; Animals ; Europe ; Insect Control/methods ; Insect Vectors/virology ; Ornithodoros/virology ; Swine
    Language English
    Publishing date 2014-12
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2212806-2
    ISSN 1948-7134 ; 1081-1710
    ISSN (online) 1948-7134
    ISSN 1081-1710
    DOI 10.1111/jvec.12098
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Human brucellosis in Portugal-Retrospective analysis of suspected clinical cases of infection from 2009 to 2016.

    Pelerito, Ana / Cordeiro, Rita / Matos, Rita / Santos, Maria Augusta / Soeiro, Sofia / Santos, João / Manita, Carla / Rio, Carla / Santo, M / Paixão, Eleonora / Nunes, Alexandra / Núncio, Sofia

    PloS one

    2017  Volume 12, Issue 7, Page(s) e0179667

    Abstract: Brucellosis is a zoonosis that is emerging in some regions of the world. Although brucellosis is a disease of obligatory declaration and is not eradicated in Portugal, no prevalence data is available in this country. In this study, we retrospectively ... ...

    Abstract Brucellosis is a zoonosis that is emerging in some regions of the world. Although brucellosis is a disease of obligatory declaration and is not eradicated in Portugal, no prevalence data is available in this country. In this study, we retrospectively analyzed the data available at the Reference Laboratory at the Portuguese National Institute of Health during the past 7 years (2009-2016) in order to get insight into the epidemiological scenario of brucellosis in Portugal. A total of 2313 biological samples from patients with clinical suspicion of brucellosis were subjected to immunological techniques for laboratory diagnosis. From 2010 to 2015, a subset of 259 samples was subjected to molecular methods. According to the available data, 167 out of 2313 (7.2%) samples had positive serology for Brucella spp. and 43 out of 259 samples (16.6%) were positive for B. melitensis by real time PCR, being classified as biovar 1 and 3. This study draws attention to the importance of integrating clinical and laboratory data of human cases in order to increase the efficacy of the response measures in case of outbreaks.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Brucellosis/epidemiology ; Child ; Female ; Humans ; Male ; Middle Aged ; Portugal/epidemiology ; Retrospective Studies ; Young Adult
    Language English
    Publishing date 2017
    Publishing country United States
    Document type Journal Article
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0179667
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  6. Article: Burkholderia pseudomallei: First case of melioidosis in Portugal.

    Pelerito, Ana / Nunes, Alexandra / Coelho, Susana / Piedade, Cátia / Paixão, Paulo / Cordeiro, Rita / Sampaio, Daniel / Vieira, Luís / Gomes, João Paulo / Núncio, Sofia

    IDCases

    2016  Volume 3, Page(s) 10–11

    Abstract: Burkholderia pseudomallei is a Gram-negative bacillus and the causative agent of melioidosis, a serious infection associated with high mortality rate in humans. It can be naturally found as an environmental saprophyte in soil or stagnant water, and rice ... ...

    Abstract Burkholderia pseudomallei is a Gram-negative bacillus and the causative agent of melioidosis, a serious infection associated with high mortality rate in humans. It can be naturally found as an environmental saprophyte in soil or stagnant water, and rice paddies that predominate in regions of endemicity such as Northeast Thailand. B. pseudomallei is a Biosafety Level 3 organism due to risks of aerosolization and severe disease and is now included in formal emergency preparedness plans and guidelines issued by various authorities in the United States and Europe. Here, we report the first case of imported melioidosis in Portugal. B. pseudomallei was isolated from the patient's blood as well as from a left gluteal abscess pus. The isolate strain showed the unusual resistance profile to first-line eradication therapy trimethroprim/sulfamethoxazole. Whole genome sequencing revealed its similarity with isolates from Southeast Asia, suggesting the Thai origin of this Portuguese isolate, which is in agreement with a recent patient's travel to Thailand.
    Language English
    Publishing date 2016-01-25
    Publishing country Netherlands
    Document type Journal Article ; Case Reports
    ZDB-ID 2745454-X
    ISSN 2214-2509
    ISSN 2214-2509
    DOI 10.1016/j.idcr.2016.01.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Ticks and tick-borne pathogens in wild birds in Greece.

    Diakou, Anastasia / Norte, Ana Cláudia / Lopes de Carvalho, Isabel / Núncio, Sofia / Nováková, Markéta / Kautman, Matej / Alivizatos, Haralambos / Kazantzidis, Savas / Sychra, Oldřich / Literák, Ivan

    Parasitology research

    2016  Volume 115, Issue 5, Page(s) 2011–2016

    Abstract: Wild birds are common hosts of ticks and can transport them for long distances, contributing to the spreading of tick-borne pathogens. The information about ticks on birds and tick-borne pathogens in Greece is limited. The present study aimed to evaluate ...

    Abstract Wild birds are common hosts of ticks and can transport them for long distances, contributing to the spreading of tick-borne pathogens. The information about ticks on birds and tick-borne pathogens in Greece is limited. The present study aimed to evaluate the prevalence and species of ticks infesting wild resident birds (mostly small passerines) in Greece, and to assess Borrelia and Rickettsia infection in the collected ticks. Detection of Borrelia burgdorferi s.l. was performed by nested PCR targeting the flaB gene. Rickettsia spp. were detected by PCR targeting the gltA and ompA genes. Seven (2 %) out of 403 birds examined in northern Greece in 2013 were infested with 15 ticks, identified as Ixodes frontalis, Ixodes acuminatus, Hyalomma marginatum, Hyalomma aegyptium and Hyalomma sp. All ticks were negative for Borrelia spp. while four of them were positive for rickettsiae (Rickettsia aeschlimannii in H. aegyptium and Rickettsia sp. in I. frontalis, H. aegyptium and H. marginatum). Ixodes acuminatus is reported for the first time in Greece and Sylvia borin is reported as a new host record for I. acuminatus.
    MeSH term(s) Animals ; Animals, Wild ; Bird Diseases/epidemiology ; Bird Diseases/microbiology ; Bird Diseases/parasitology ; Birds ; Borrelia/isolation & purification ; Greece/epidemiology ; Ixodidae/microbiology ; Passeriformes ; Rickettsia/isolation & purification ; Tick Infestations/epidemiology ; Tick Infestations/parasitology ; Tick Infestations/veterinary
    Language English
    Publishing date 2016-05
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 284966-5
    ISSN 1432-1955 ; 0932-0113 ; 0044-3255
    ISSN (online) 1432-1955
    ISSN 0932-0113 ; 0044-3255
    DOI 10.1007/s00436-016-4943-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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