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  1. Article ; Online: Kulbulahat [Hindi]

    Neha Sharma

    Research and Humanities in Medical Education, Vol 7, Pp 45-

    2020  Volume 46

    Keywords covid19 ; coronavirus ; कुलबुलाहट ; health humanities ; medical humanities ; physician ; pandemic ; poem ; poetry in medicine ; Medicine (General) ; R5-920 ; Medical philosophy. Medical ethics ; R723-726
    Language English
    Publishing date 2020-04-01T00:00:00Z
    Publisher University College of Medical Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Bio-psycho-social Intervention for Relapse Prevention among Males with Substance Dependence

    NEHA SHARMA

    Dev Sanskriti: Interdisciplinary International Journal, Vol

    2018  Volume 12

    Abstract: Relapse poses a fundamental barrier to the treatment of substance dependence. Preventing relapse is therefore a prerequisite for any attempt to facilitate successful and long-term behavioral changes in substance dependents. Relapse can be caused by ... ...

    Abstract Relapse poses a fundamental barrier to the treatment of substance dependence. Preventing relapse is therefore a prerequisite for any attempt to facilitate successful and long-term behavioral changes in substance dependents. Relapse can be caused by biological, psychological and socio-cultural reasons hence this study was aimed to develop and implement a bio-psycho-social intervention program for relapse prevention. 100 male subjects having multiple substance dependence from 16 to 60 years of age were selected through purposive sampling. Subjects were assessed on ‘Advance warning of relapse questionnaire’ followed by a follow up study through telephonic interview for six months. Two null hypotheses were formulated to see the effect of intervention on relapse prevention. Between two groups research design was used for the study with 50 subjects in each group. Data was analyzed by using t and 2x2 contingency χ2 tests. For first hypothesis was significant at 0.01 level and concluded that intervention program reduced advance warning signs of relapse. For second hypothesis 74% experimental group subjects were abstinent till six months after intervention as compared to 22% of control group. It was concluded that bio-psycho-social intervention program is significantly effective in relapse prevention among males with substance dependence.
    Keywords substance dependence ; advance warning of relapse ; relapse prevention ; bio-psycho-social intervention ; Other systems of medicine ; RZ201-999
    Subject code 796
    Language English
    Publishing date 2018-07-01T00:00:00Z
    Publisher Dr. Chinmay Pandya
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Dietary factors associated with gastric cancer - a review

    Richa / Neha Sharma / Geetanjali Sageena

    Translational Medicine Communications, Vol 7, Iss 1, Pp 1-

    2022  Volume 11

    Abstract: Abstract Background Cancer is considered one of the primary illnesses that cause morbidity and mortality in millions of people worldwide and due to its prevalence, there is undoubtedly an unmet need to discover novel anticancer drugs. As most of the ... ...

    Abstract Abstract Background Cancer is considered one of the primary illnesses that cause morbidity and mortality in millions of people worldwide and due to its prevalence, there is undoubtedly an unmet need to discover novel anticancer drugs. As most of the target-specific anticancer drugs failed to achieve the expected result so far, new multi-targeted therapies using natural products have become significant. Natural products are readily applicable, inexpensive, accessible and acceptable therapeutic approaches with minimum cytotoxicity. This review explores the relationship between dietary factors and the probability of development of gastric cancer. Over the years, it has been proven that there are many natural products that have chemo-preventative effects such as vitamins, probiotics and prebiotics, green tea, and resveratrol on gastric cancer. Many investigations have looked into the links between dietary components and the risk of stomach cancer and a variety of protective and deleterious factors have been identified in our diet that is associated with gastric cancer. In this study, we have summarized the preventive and injurious components that affect the incidence of gastric cancer. Conclusion Based on the potential of natural products for the discovery of new compounds for the treatment of diseases, the purpose of the present review was to investigate the importance of dietary products mitigating the impacts due to the development of gastric cancer. The current analysis proves the protective as well as harmful roles of many elements which are found in our diet in the development of gastric cancer. Our findings can have significant public health implications in terms of gastric cancer prevention. There is an inherent need to offer an insight into benefits and risks, clinical trial designs future translational and cohort studies before effectively clinically translated.
    Keywords Gastric cancer ; Diet ; Alcohol in stomach cancer ; Carcinogens in diet ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Deep temporal networks for EEG-based motor imagery recognition

    Neha Sharma / Avinash Upadhyay / Manoj Sharma / Amit Singhal

    Scientific Reports, Vol 13, Iss 1, Pp 1-

    2023  Volume 12

    Abstract: Abstract The electroencephalogram (EEG) based motor imagery (MI) signal classification, also known as motion recognition, is a highly popular area of research due to its applications in robotics, gaming, and medical fields. However, the problem is ill- ... ...

    Abstract Abstract The electroencephalogram (EEG) based motor imagery (MI) signal classification, also known as motion recognition, is a highly popular area of research due to its applications in robotics, gaming, and medical fields. However, the problem is ill-posed as these signals are non-stationary and noisy. Recently, a lot of efforts have been made to improve MI signal classification using a combination of signal decomposition and machine learning techniques but they fail to perform adequately on large multi-class datasets. Previously, researchers have implemented long short-term memory (LSTM), which is capable of learning the time-series information, on the MI-EEG dataset for motion recognition. However, it can not model very long-term dependencies present in the motion recognition data. With the advent of transformer networks in natural language processing (NLP), the long-term dependency issue has been widely addressed. Motivated by the success of transformer algorithms, in this article, we propose a transformer-based deep learning neural network architecture that performs motion recognition on the raw BCI competition III IVa and IV 2a datasets. The validation results show that the proposed method achieves superior performance than the existing state-of-the-art methods. The proposed method produces classification accuracy of 99.7% and 84% on the binary class and the multi-class datasets, respectively. Further, the performance of the proposed transformer-based model is also compared with LSTM.
    Keywords Medicine ; R ; Science ; Q
    Subject code 006
    Language English
    Publishing date 2023-11-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Chronic Tubulointerstitial Nephropathy of Agricultural Communities

    Sourabh Sharma / Neha Sharma / Urmila Anandh / Swarnalata Gowrishankar

    Kidney and Dialysis, Vol 3, Iss 21, Pp 229-

    2023  Volume 243

    Abstract: Chronic interstitial nephritis in agricultural communities is an emerging public health concern affecting numerous agricultural communities in tropical countries, including regions in India, with a significant impact on the health and well-being of ... ...

    Abstract Chronic interstitial nephritis in agricultural communities is an emerging public health concern affecting numerous agricultural communities in tropical countries, including regions in India, with a significant impact on the health and well-being of affected individuals. The affected individuals suffer from various psychosocial, nutritional, and metabolic challenges due to organ failure, which affects their quality of life. The etiology remains poorly understood, and various risk factors, which include various environmental and occupational hazards, have been implicated in its development. The recent discovery of lysosomal proximal tubulopathy has reignited interest in its pathogenesis. Along with the representative feature of chronic interstitial nephritis, changes suggestive of tubular injury have also been reported. It is suggested to use the term “chronic tubulointerstitial nephropathy of agricultural community” instead of chronic interstitial nephritis of the agricultural communities. Chronic tubulointerstitial nephropathy in agricultural communities is a slowly progressive disease that initially does not cause any symptoms in patients and most patients have a delayed onset of symptoms. Several diagnostic criteria have been introduced over the past years and one introduced by the Ministry of Health of Sri Lanka is widely used. The management of this chronic illness is no different from other causes of chronic interstitial nephritis and our focus should be on implementing various preventive strategies to reduce its incidence in agricultural communities and protect the health and well-being of agricultural workers. By disseminating knowledge about chronic tubulointerstitial nephropathy in agricultural communities, we can contribute to the development of evidence-based interventions to reduce the burden of the disease on affected communities. Moreover, we would like to sensitize physicians to this entity to increase awareness and identify potential endemic areas in various agricultural communities.
    Keywords chronic interstitial nephritis ; chronic interstitial nephritis of agricultural communities ; preventive nephrology ; lysosomal proximal tubulopathy ; CKDu ; Internal medicine ; RC31-1245
    Subject code 306
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Can Steam Sterilization Affect the Accuracy of Point-of-Care 3D Printed Polyetheretherketone (PEEK) Customized Cranial Implants? An Investigative Analysis

    Neha Sharma / Jokin Zubizarreta-Oteiza / Céline Tourbier / Florian M. Thieringer

    Journal of Clinical Medicine, Vol 12, Iss 2495, p

    2023  Volume 2495

    Abstract: Polyetheretherketone (PEEK) has become the biomaterial of choice for repairing craniofacial defects over time. Prospects for the point-of-care (POC) fabrication of PEEK customized implants have surfaced thanks to the developments in three-dimensional (3D) ...

    Abstract Polyetheretherketone (PEEK) has become the biomaterial of choice for repairing craniofacial defects over time. Prospects for the point-of-care (POC) fabrication of PEEK customized implants have surfaced thanks to the developments in three-dimensional (3D) printing systems. Consequently, it has become essential to investigate the characteristics of these in-house fabricated implants so that they meet the necessary standards and eventually provide the intended clinical benefits. This study aimed to investigate the effects of the steam sterilization method on the dimensional accuracy of POC 3D-printed PEEK customized cranial implants. The objective was to assess the influence of standard sterilization procedures on material extrusion-based 3D-printed PEEK customized implants with non-destructive material testing. Fifteen PEEK customized cranial implants were fabricated using an in-house material extrusion-based 3D printer. After fabrication, the cranial implants were digitalized with a professional-grade optical scanner before and after sterilization. The dimensional changes for the 3D-printed PEEK cranial implants were analyzed using medically certified 3D image-based engineering software. The material extrusion 3D-printed PEEK customized cranial implants displayed no statistically significant dimensional difference with steam sterilization ( p > 0.05). Evaluation of the cranial implants’ accuracy revealed that the dimensions were within the clinically acceptable accuracy level with deviations under 1.00 mm. Steam sterilization does not significantly alter the dimensional accuracy of the in-house 3D-printed PEEK customized cranial implants.
    Keywords accuracy ; alloplastic implant ; computer-assisted ; cranioplasty ; material extrusion ; patient-specific ; Medicine ; R
    Subject code 660
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: ‘Triangle Ester’ Molecules as Blending Components in Mineral Oil

    Neha Sharma / Sunil Kumar / Gananath D. Thakre / Anjan Ray

    Lubricants, Vol 11, Iss 144, p

    A Theoretical and Experimental Investigation

    2023  Volume 144

    Abstract: The present work explored the use of fatty acid ‘Triangle ester’ molecules (Epoxidized Ester (EE), and Thiirane Ester (TE)) as antifriction and antiwear additives at varying levels for Group I and Group II mineral base oils using the standard ASTMD-4172B ...

    Abstract The present work explored the use of fatty acid ‘Triangle ester’ molecules (Epoxidized Ester (EE), and Thiirane Ester (TE)) as antifriction and antiwear additives at varying levels for Group I and Group II mineral base oils using the standard ASTMD-4172B four-ball test. Relative to neat base oil, EE blends showed improved antifriction by ~61% and ~42% and antiwear properties by ~32% and ~41% in Group I and Group II base oils, respectively, while the TE blends showed friction reduction by ~65% and ~40% and wear reduction by ~93% and ~50% relative to the same neat base stock. Time evolution of the ‘Triangle ester’ molecules and their blends with mineral oil (modeled as hexadecane) w.r.t. conformational changes, adsorption energy, intermolecular energy, and effect of the applied stress were estimated theoretically using MD simulations. Further, optimized levels of these additives were explored for their effectiveness as a blending component for commercial engine oil (CEO) and could reduce the friction and wear of CEO by ~50% and ~30%, respectively.
    Keywords triangle ester ; additives ; molecular dynamics ; friction ; wear ; Science ; Q
    Subject code 670
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Rice straw-derived cellulose

    Neha Sharma / Benjamin James Allardyce / Rangam Rajkhowa / Ruchi Agrawal

    Scientific Reports, Vol 13, Iss 1, Pp 1-

    a comparative study of various pre-treatment technologies and its conversion to nanofibres

    2023  Volume 12

    Abstract: Abstract Rice straw is a waste product generated after the harvesting of rice crops and is commonly disposed of by burning it off in open fields. This study explored the potential for the extraction and conversion of cellulose to cellulose nanofibres ( ... ...

    Abstract Abstract Rice straw is a waste product generated after the harvesting of rice crops and is commonly disposed of by burning it off in open fields. This study explored the potential for the extraction and conversion of cellulose to cellulose nanofibres (CNFs) to be used as smart delivery systems for fertilizers applications. In this study, alkali, steam explosion, and organosolv treatments were investigated for cellulose extraction efficiency. The morphological characterization of cellulose showed smooth fibrillar structures. Fourier transform infrared spectroscopy represented significant removal of non-cellulosic components in treatments. The crystallinity increased from 52.2 to 65% in CNFs after fibrillation. Cellulose nanofibres (CNFs) had an average diameter of 37.4 nm and − 25.2 mV surface charges as determined by SEM and zeta potential, respectively, which have desired properties for holding fertilizers. Therefore, this study paves the way for value-added uses of rice straw as alternatives to current environmentally harmful practices.
    Keywords Medicine ; R ; Science ; Q
    Subject code 620
    Language English
    Publishing date 2023-09-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: A regioselective synthesis of β-difluoromethoxy vinyl sulfones

    Ishu, Km / Prabhakar, Neha Sharma / Singh, Krishna Nand

    Organic & biomolecular chemistry

    2023  Volume 21, Issue 32, Page(s) 6588–6594

    Abstract: A practical synthesis of new β-difluoromethoxy vinyl sulfones has been explored ... ...

    Abstract A practical synthesis of new β-difluoromethoxy vinyl sulfones has been explored by
    Language English
    Publishing date 2023-08-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2097583-1
    ISSN 1477-0539 ; 1477-0520
    ISSN (online) 1477-0539
    ISSN 1477-0520
    DOI 10.1039/d3ob01142a
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  10. Article ; Online: Visible-Light-Mediated Synthesis of α-Ketoamides via Oxidative Amination of 2-Bromoacetophenones Using Eosin Y as a Photoredox Catalyst.

    Kishor, Kaushal / Prabhakar, Neha Sharma / Singh, Krishna Nand

    Chemistry, an Asian journal

    2023  Volume 18, Issue 19, Page(s) e202300669

    Abstract: An oxidative amination of 2-bromoacetophenones has been accomplished to provide α-ketoamides by using photoredox catalysis with air as oxidant. The reactants are readily accessible, and the method is endowed with broad substrate scope and good functional ...

    Abstract An oxidative amination of 2-bromoacetophenones has been accomplished to provide α-ketoamides by using photoredox catalysis with air as oxidant. The reactants are readily accessible, and the method is endowed with broad substrate scope and good functional group tolerance. The practicality of the approach is also shown by a gram-scale reaction.
    Language English
    Publishing date 2023-09-05
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2233006-9
    ISSN 1861-471X ; 1861-4728
    ISSN (online) 1861-471X
    ISSN 1861-4728
    DOI 10.1002/asia.202300669
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