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Article ; Online: Research progress on occupational hazards of cosmic radiation for aircrew

Yizhe SUN / Yongbin LUO / Na TU

环境与职业医学, Vol 39, Iss 3, Pp 337-

2022 Volume 342

Abstract: According to the data released by the Civil Aviation Administration of China in 2020, there are more than 60000 pilots and more than 100000 flight attendants in China working with certificates in various airlines. The health of these aircrew is the basis ...

Abstract	According to the data released by the Civil Aviation Administration of China in 2020, there are more than 60000 pilots and more than 100000 flight attendants in China working with certificates in various airlines. The health of these aircrew is the basis for maintaining and continuing the smooth development of civil aviation. Aircrew are exposed to cosmic radiation at high altitudes. However, because the types of cosmic radiation are complex, changeable, and difficult to measure accurately, there is no definite conclusion as to whether it has any effect on the health of aircrew. This paper introduced the impacts of cosmic radiation on aircrew, reviewed the estimation of cosmic radiation dose at home and abroad, and summarized the cosmic radiation dose measurement methods and their limitations. It also pointed out the shortcomings of existing occupational health management of aircrew and put forward new suggestions on strengthening the health management of radiation hazards for aircrew.
Keywords	aircrew ; cosmic radiation ; radiation hazard ; cosmic radiation dose ; method of dose estimation ; Medicine (General) ; R5-920 ; Toxicology. Poisons ; RA1190-1270
Subject code	535
Language	English
Publishing date	2022-03-01T00:00:00Z
Publisher	Editorial Committee of Journal of Environmental and Occupational Medicine
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Whole-exome sequencing and genome-wide evolutionary analyses identify novel candidate genes associated with infrared perception in pit vipers

Na Tu / Dan Liang / Peng Zhang

Scientific Reports, Vol 10, Iss 1, Pp 1-

2020 Volume 13

Abstract: Abstract Pit vipers possess a unique thermal sensory system consisting of facial pits that allow them to detect minute temperature fluctuations within their environments. Biologists have long attempted to elucidate the genetic basis underlying the ... ...

Abstract	Abstract Pit vipers possess a unique thermal sensory system consisting of facial pits that allow them to detect minute temperature fluctuations within their environments. Biologists have long attempted to elucidate the genetic basis underlying the infrared perception of pit vipers. Early studies have shown that the TRPA1 gene is the thermal sensor associated with infrared detection in pit vipers. However, whether genes other than TRPA1 are also involved in the infrared perception of pit vipers remains unknown. Here, we sequenced the whole exomes of ten snake species and performed genome-wide evolutionary analyses to search for novel candidate genes that might be involved in the infrared perception of pit vipers. We applied both branch-length-comparison and selection-pressure-alteration analyses to identify genes that specifically underwent accelerated evolution in the ancestral lineage of pit vipers. A total of 47 genes were identified. These genes were significantly enriched in the ion transmembrane transporter, stabilization of membrane potential, and temperature gating activity functional categories. The expression levels of these candidate genes in relevant nerve tissues (trigeminal ganglion, dorsal root ganglion, midbrain, and cerebrum) were also investigated in this study. We further chose one of our candidate genes, the potassium channel gene KCNK4, as an example to discuss its possible role in the infrared perception of pit vipers. Our study provides the first genome-wide survey of infrared perception-related genes in pit vipers via comparative evolutionary analyses and reveals valuable candidate genes for future functional studies.
Keywords	Medicine ; R ; Science ; Q
Subject code	572
Language	English
Publishing date	2020-08-01T00:00:00Z
Publisher	Nature Publishing Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Ecological stoichiometric characteristics of soil-moss C, N, and P in restoration stages of karst rocky desertification.

Wenping Meng / Quanhou Dai / Qingqing Ren / Na Tu / Tingjiao Leng

PLoS ONE, Vol 16, Iss 6, p e

2021 Volume 0252838

Abstract: Rocky desertification is the most serious ecological disaster in karst areas. Comprehensive control of rocky desertification plays an important role in promoting the economic development of karst areas. Studying the stoichiometric characteristics of ... ...

Abstract	Rocky desertification is the most serious ecological disaster in karst areas. Comprehensive control of rocky desertification plays an important role in promoting the economic development of karst areas. Studying the stoichiometric characteristics of mosses and soil can provide a powerful reference for the ecological restoration and evaluation of ecosystems experiencing rocky desertification. Soil and mosses were collected from sites representing different stages of ecological restoration (bare rock, grassland, shrubland, and secondary forest), and the contents of carbon (C), nitrogen (N), and phosphorus (P) were detected for ecological stoichiometric analysis. The results indicate that in different restoration stages following karst rocky desertification, the contents of soil organic carbon (SOC), total nitrogen (TN), and total phosphorus (TP) and the stoichiometric ratios in the shrub habitat are higher than those in the bare rock, grassland, and secondary forest habitats. However, the TP and available P contents were low at all stages (0.06 g/kg and 0.62 mg/kg, respectively). The N and P contents and stoichiometric ratios in the mosses showed no significant differences among the succession stages. The C contents in the mosses had a significant positive correlation with SOC and TN and TP content, and the P content had a significant positive correlation with the soil available P. However, there was a significant negative correlation between the C: N and C:P ratios of the bryophytes and soil C: N. In summary, during the process of natural restoration of karst rocky desertification areas, SOC and soil TN contents accumulate with each succession stage. Soil nutrients are higher in shrub habitats than in other succession stages. Mosses have a strong effect on improving soil nutrients in rocky desertification areas.
Keywords	Medicine ; R ; Science ; Q
Subject code	910
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The Mitochondrial Response to DNA Damage

Ziye Rong / Peipei Tu / Peiqi Xu / Yan Sun / Fangfang Yu / Na Tu / Lixia Guo / Yanan Yang

Frontiers in Cell and Developmental Biology, Vol

2021 Volume 9

Abstract: Mitochondria are double membrane organelles in eukaryotic cells that provide energy by generating adenosine triphosphate (ATP) through oxidative phosphorylation. They are crucial to many aspects of cellular metabolism. Mitochondria contain their own DNA ... ...

Abstract	Mitochondria are double membrane organelles in eukaryotic cells that provide energy by generating adenosine triphosphate (ATP) through oxidative phosphorylation. They are crucial to many aspects of cellular metabolism. Mitochondria contain their own DNA that encodes for essential proteins involved in the execution of normal mitochondrial functions. Compared with nuclear DNA, the mitochondrial DNA (mtDNA) is more prone to be affected by DNA damaging agents, and accumulated DNA damages may cause mitochondrial dysfunction and drive the pathogenesis of a variety of human diseases, including neurodegenerative disorders and cancer. Therefore, understanding better how mtDNA damages are repaired will facilitate developing therapeutic strategies. In this review, we focus on our current understanding of the mtDNA repair system. We also discuss other mitochondrial events promoted by excessive DNA damages and inefficient DNA repair, such as mitochondrial fusion, fission, and mitophagy, which serve as quality control events for clearing damaged mtDNA.
Keywords	mitochondrial DNA ; DNA repair ; mitochondrial fusion ; mitochondrial fission ; mitophagy ; Biology (General) ; QH301-705.5
Subject code	612
Language	English
Publishing date	2021-05-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Initial Analysis on the Characteristics and Synthesis of Exopolysaccharides from Sclerotium rolfsii with Different Sugars as Carbon Sources

Jia Song / Yu-Xiang Jia / Yan Su / Xiao-Yu Zhang / Lin-Na Tu / Zhi-Qiang Nie / Yu Zheng / Min Wang

Polymers, Vol 12, Iss 2, p

2020 Volume 348

Abstract: Scleroglucan is widely used in the food and chemical industries because of its good rheological property, stability, and emulsification activity. To investigate the influence of different carbon sources on the properties and synthesis of ... ...

Abstract	Scleroglucan is widely used in the food and chemical industries because of its good rheological property, stability, and emulsification activity. To investigate the influence of different carbon sources on the properties and synthesis of exopolysaccharides (EPS), the three EPSs (GEPS, glucose was used as the carbon source; LEPS, lactose was used as the carbon source; and SEPS, sucrose was used as the carbon source) were determined, respectively. It was found that the yield and viscosity of exopolysaccharides were different. When sucrose and glucose were used as the carbon sources, the viscosity and yield of EPS were both higher than lactose. The scanning electron microscopy (SEM) images showed that the three EPSs had different morphologies, but the monosaccharide analysis showed that they were all composed of glucose units. Fourier transform infrared spectroscopy (FT-IR) proved that there were no additional substituents for the three EPSs. Furthermore, the high performance liquid chromatography (HPLC) results showed that SEPS and LEPS had two fractions. Through the analysis of proteomics data, there were few differences in the metabolic pathways between GEPS and SEPS, but a significant difference between LEPS and SEPS. Our study provides a theoretical basis and reference for understanding the biosynthesis of exopolysaccharides and the development of different types of EPS products.
Keywords	sclerotium rolfsii ; exopolysaccharides ; carbon sources ; characteristic ; proteome ; Organic chemistry ; QD241-441
Subject code	540
Language	English
Publishing date	2020-02-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Exposures to IARC Carcinogenic Agents in Work Settings Not Traditionally Associated with Sinonasal Cancer Risk: The Experience of the Italian National Sinonasal Cancer Registry.

Binazzi, Alessandra / Mensi, Carolina / Miligi, Lucia / Di Marzio, Davide / Zajacova, Jana / Galli, Paolo / Camagni, Angela / Calisti, Roberto / Balestri, Anna / Murano, Stefano / Piro, Sara / d'Errico, Angelo / Bonzini, Matteo / Massacesi, Stefania / Sorasio, Denise / Marinaccio, Alessandro / On Behalf Of ReNaTuNS Working Group

International journal of environmental research and public health

2021 Volume 18, Issue 23

Abstract: The aim of this study is to highlight tasks and jobs not commonly considered at high risk for sinonasal cancer (SNC) identified by Regional Operating Centers currently active in the Italian National Sinonasal Cancer Registry (ReNaTuNS), which retrieve ... ...

Abstract	The aim of this study is to highlight tasks and jobs not commonly considered at high risk for sinonasal cancer (SNC) identified by Regional Operating Centers currently active in the Italian National Sinonasal Cancer Registry (ReNaTuNS), which retrieve occupational histories through a standardized questionnaire. Data on exposures to IARC carcinogenic agents in work settings unknown to be associated with SNC risk were collected and analyzed. Out of 2,208 SNC cases recorded in the ReNaTuNS database, 216 cases and their worked exposure periods were analyzed. Unsuspected jobs with exposure to wood dust include construction-related tasks, production of resins, agriculture and livestock jobs (straw and sawdust), and heel factory work (cork dust). Other examples are hairdressers, bakers (formaldehyde), dressmakers, technical assistants, wool and artificial fiber spinners, and upholsterers (textile dusts). Moreover, settings with coexposure to different agents (e.g., wood with leather dusts and chromium-nickel compounds) were recognized. The study describes jobs where the existence of carcinogenic agents associated with SNC risk is unexpected or not resulting among primary materials employed. The systematic epidemiological surveillance of all epithelial SNC cases with a detailed collection of their work history, as performed by a dedicated population registry, is essential for detecting all potential occupational cases and should be considered in the context of forensic medicine and the compensation process.
MeSH term(s)	Carcinogens/toxicity ; Dust ; Humans ; Occupational Diseases/chemically induced ; Occupational Diseases/epidemiology ; Occupational Exposure ; Paranasal Sinus Neoplasms/chemically induced ; Paranasal Sinus Neoplasms/epidemiology ; Registries
Chemical Substances	Carcinogens ; Dust
Language	English
Publishing date	2021-11-29
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph182312593
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Exposures to IARC Carcinogenic Agents in Work Settings Not Traditionally Associated with Sinonasal Cancer Risk

Alessandra Binazzi / Carolina Mensi / Lucia Miligi / Davide Di Marzio / Jana Zajacova / Paolo Galli / Angela Camagni / Roberto Calisti / Anna Balestri / Stefano Murano / Sara Piro / Angelo d’Errico / Matteo Bonzini / Stefania Massacesi / Denise Sorasio / Alessandro Marinaccio / on behalf of ReNaTuNS Working group

International Journal of Environmental Research and Public Health, Vol 18, Iss 12593, p

The Experience of the Italian National Sinonasal Cancer Registry

2021 Volume 12593

Abstract	The aim of this study is to highlight tasks and jobs not commonly considered at high risk for sinonasal cancer (SNC) identified by Regional Operating Centers currently active in the Italian National Sinonasal Cancer Registry (ReNaTuNS), which retrieve occupational histories through a standardized questionnaire. Data on exposures to IARC carcinogenic agents in work settings unknown to be associated with SNC risk were collected and analyzed. Out of 2,208 SNC cases recorded in the ReNaTuNS database, 216 cases and their worked exposure periods were analyzed. Unsuspected jobs with exposure to wood dust include construction-related tasks, production of resins, agriculture and livestock jobs (straw and sawdust), and heel factory work (cork dust). Other examples are hairdressers, bakers (formaldehyde), dressmakers, technical assistants, wool and artificial fiber spinners, and upholsterers (textile dusts). Moreover, settings with coexposure to different agents (e.g., wood with leather dusts and chromium–nickel compounds) were recognized. The study describes jobs where the existence of carcinogenic agents associated with SNC risk is unexpected or not resulting among primary materials employed. The systematic epidemiological surveillance of all epithelial SNC cases with a detailed collection of their work history, as performed by a dedicated population registry, is essential for detecting all potential occupational cases and should be considered in the context of forensic medicine and the compensation process.
Keywords	sinonasal cancer ; occupational exposure ; occupational cancer ; epidemiological surveillance ; Medicine ; R
Subject code	610
Language	English
Publishing date	2021-11-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Oxidation resistance of flavonoids in Chinese jujube stone

Zhang Na, Tarim University, Alar (China), College of Life Sciences / Yang Baoqiu, Tarim University, Alar (China), College of Life Sciences / Wang Qian, Tarim University, Alar (China), College of Life Sciences

Agricultural Science and Technology

Jan. 2011 , Issue (8)

Abstract: Objective] The aim was to study on the oxidation resistance of flavonoids in Chinese jujube stone. [Method] The extract of flavonoids from Chinese jujube stone was added to fresh rapeseed oil and lard to explore the oxidation resistance of flavonoids; ... ...

Abstract	[Objective] The aim was to study on the oxidation resistance of flavonoids in Chinese jujube stone. [Method] The extract of flavonoids from Chinese jujube stone was added to fresh rapeseed oil and lard to explore the oxidation resistance of flavonoids; the removal rates of it to O2-_ DPPH_and �OH were also studied. [Result] The flavonoids from Chinese jujube stone had good oxidation resistance on rapeseed oil and lard, and the effects showed dose-dependent; citric acid and vitamin C appeared synergistic effects to the flavonoids; in free-radical reaction experiment, the flavonoids from Chinese Jujube stone also showed strong scavenging ability on O2-_ DPPH_and �OH, in addition, the scavenging ability increased with concentration increasing. [Conclusion] The result of this study had provided theoretical basis for the further development and utilization of Chinese jujube resource.
Keywords	ZIZIPHUS ; FLAVONOIDS ; OXIDATION ; ZIZIPHUS ; FLAVONOIDE ; OXYDATION ; ZIZIPHUS ; FLAVONOIDES ; OXIDACION ; http://www.fao.org/aos/agrovoc#c_8525 ; http://www.fao.org/aos/agrovoc#c_2964 ; http://www.fao.org/aos/agrovoc#c_5472
Language	zho
Document type	Article
ISSN	1009-4229
Database	AGRIS - International Information System for the Agricultural Sciences and Technology

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Article: [Correlates of bronchial asthma in Uygur and Han adults in Turpan prefecture, Xinjiang].

Wang, Jing / Qi, Man-Gu-Li Wu-Shou-Er / Li, Xia / He, Yuan-bing / Ke, Li-Bie-Na Tu-Er-Xun / Wen, Jin / Ju, Lai-Ti Mu-Ta-Li-Fu

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine

2009 Volume 43, Issue 10, Page(s) 907–912

Abstract: Objective: To analyze possible difference in bronchial asthma between ethnic and geographic groups and explore its correlates among Uygur and Han adults in Turpan Prefecture, Xinjiang.: Methods: One hundred and sixty-six clinically diagnosed ... ...

Abstract	Objective: To analyze possible difference in bronchial asthma between ethnic and geographic groups and explore its correlates among Uygur and Han adults in Turpan Prefecture, Xinjiang. Methods: One hundred and sixty-six clinically diagnosed asthmatic patients at Turpan Prefecture Hospital, Xinjiang, 86 of Uygur and 80 of Han ethnic, and 166 1:1 matched controls from ophthalmological outpatient department at the same hospital were recruited into the study. Interview with questionnaire was conducted and serum levels of eosinophilic cation protein (S-ECP), total IgE (T-IgE) and specific IgE (S-IgE) were measured for all of the participants to study related factors for asthma with univariate and multivariate conditional logistic regression analyses. Results: Bronchial infection (OR(U) = 5.111, 95%CI: 1.203 - 21.710; OR(H) = 2.498, 95%CI: 1.471 - 5.069), family history of asthma (OR(U) = 3.078, 95%CI: 1.812 - 5.188; OR(H) = 2.711, 95%CI: 1.010 - 6.176), personal allergy history (OR(U) = 2.083, 95%CI: 1.043 - 4.162; OR(H) = 3.998, 95%CI: 1.739 - 9.198), weather change (OR(U) = 2.218, 95%CI: 1.199 - 3.778; OR(H) = 1.733, 95%CI: 1.004 - 2.994) and positive S-IgE (OR(U) = 1.592, 95%CI: 1.018 - 2.491; OR(H) = 3.858, 95%CI: 2.246 - 8.507) correlated with asthma in patients of both Uygur and Han ethnic. Percentage of asthma attack induced by respiratory infection [59.30% (51/86)] and weather change [36.05% (31/86)] in Uygur patients was significantly higher than that in Han ethnic [42.50% (34/80) and 21.25% (17/80), respectively], but percentage of those with personal allergy history [48.75% (39/80)] and positive S-IgE [52.50% (42/80)] in Han ethnic was significantly higher than that in Uygur [32.56% (28/86) and 30.23% (26/86), respectively]. Levels of S-ECP and T-IgE in patients with moderate and severe asthma of both Uygur and Han ethnic [(S-ECP(U) = 7.95 +/- 3.98) microg/L, S-ECP(H) = (11.21 +/- 4.74) microg/L, T- IgE(U) = (72.23 +/- 45.92) kU/L, T-IgE(H) = (108.81 +/- 64.07) kU/L, respectively]were significantly higher than those in controls of the same ethnic [S- ECP(U) = (1.94 +/- 1.16) microg/L, S-ECP(H) = (2.07 +/- 1.63) microg/L, T-IgE(U) = (46.19 +/- 32.47) kU/L, T-IgE(H) = (50.97 +/- 38.51) kU/L; t values were 8.96, 10.52, 2.81, 4.97, P < 0.01], higher in Han ethnic than those in Uygur (t values were 3.01, 2.68, P < 0.01). Conclusion: Bronchial infection, family asthma history, personal allergy history, weather change and positive S-IgE all were important correlates of asthma in Turpan Prefecture, Xinjiang. Levels of S-ECP and T-IgE in patients with moderate and severe asthma increased during its attacks, higher in Han ethnic than those in Uygur. Genetic and environmental factors may be involved in occurrence and development of asthma.
MeSH term(s)	Adult ; Asthma/blood ; Asthma/epidemiology ; Asthma/ethnology ; Causality ; China/epidemiology ; Climate ; Environmental Exposure ; Eosinophil Cationic Protein/blood ; Female ; Humans ; Immunoglobulin E/blood ; Logistic Models ; Male ; Pedigree ; Surveys and Questionnaires
Chemical Substances	Immunoglobulin E (37341-29-0) ; Eosinophil Cationic Protein (EC 3.1.27.-)
Language	Chinese
Publishing date	2009-10
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	604575-3
ISSN	0253-9624
ISSN	0253-9624
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Influence of rainfall run-off in hydrologic process on non-point pollution

Jiang Jin, Tongji University, Shanghai （China）, National Key Lab of Pollution Control and Resource Study / An Na, Tongji University, Shanghai （China）, National Key Lab of Pollution Control and Resource Study / Gao Neiyun, Tongji University, Shanghai （China）, National Key Lab of Pollution Control and Resource Study

Agricultural Science and Technology

Feb.2012 Volume v. 13, Issue (2), Page(s) p. 380–383, 444

Abstract: 目的]研究降雨径流对非点源污染的影响，拟通过控制降雨径流产生的污染来减少非点源污染。[方法]通过分析降雨径流的水文过程、其与非点源污染物的作用机理及其对非点源污染的影响，以及水文模型在该研究中的应用，探讨如何有效的减少非点源污染。[结果]降雨径流是非点源污染的主要原因，通过源头控制，加强地表非点源污染物清除和控制，在坡地上种植植被，可有效减少降雨径流对土地的冲刷和侵蚀，减少水土流失。水文模型的应用使该研究简单化。[结论]研究表明对降雨径流过程进行控制将有效减少非点源污染。 ...

Abstract	[目的]研究降雨径流对非点源污染的影响，拟通过控制降雨径流产生的污染来减少非点源污染。[方法]通过分析降雨径流的水文过程、其与非点源污染物的作用机理及其对非点源污染的影响，以及水文模型在该研究中的应用，探讨如何有效的减少非点源污染。[结果]降雨径流是非点源污染的主要原因，通过源头控制，加强地表非点源污染物清除和控制，在坡地上种植植被，可有效减少降雨径流对土地的冲刷和侵蚀，减少水土流失。水文模型的应用使该研究简单化。[结论]研究表明对降雨径流过程进行控制将有效减少非点源污染。
Keywords	POLLUTION ; RAIN ; HYDROLOGY ; POLLUTION ; PLUIE ; HYDROLOGIE ; POLUCION ; LLUVIA ; HIDROLOGIA ; http://www.fao.org/aos/agrovoc#c_6077 ; http://www.fao.org/aos/agrovoc#c_6435 ; http://www.fao.org/aos/agrovoc#c_3731
Language	zho
Document type	Article
ISSN	1009-4229
Database	AGRIS - International Information System for the Agricultural Sciences and Technology

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