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  1. Article ; Online: Immune Response in Severe Infection

    Maja Surbatovic / Jasna Jevdjic / Milic Veljovic / Nada Popovic / Dragan Djordjevic / Sonja Radakovic

    The Scientific World Journal, Vol

    Could Life-Saving Drugs Be Potentially Harmful?

    2013  Volume 2013

    Abstract: Critically ill patients suffer a high rate of nosocomial infection with secondary sepsis being a common cause of death. Usage of antibiotics and catecholamines is often necessary, but it can compromise complex immune response to infection. This review ... ...

    Abstract Critically ill patients suffer a high rate of nosocomial infection with secondary sepsis being a common cause of death. Usage of antibiotics and catecholamines is often necessary, but it can compromise complex immune response to infection. This review explores influence of these life-saving drugs on host immune response to severe infection.
    Keywords Technology ; T ; Medicine ; R ; Science ; Q
    Language English
    Publishing date 2013-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Structure and morphology of nano-sized W–Ti/Si thin films

    BORIVOJE ADNADJEVIC / DAVOR PERUSKO / NADA POPOVIC / NENAD BUNDALESKI / MILAN RADOVIC / BILJANA GAKOVIC / ZLATKO RAKOCEVIC

    Journal of the Serbian Chemical Society, Vol 71, Iss 8-9, Pp 969-

    2006  Volume 976

    Abstract: Thin films were deposited by d.c. sputtering onto a silicon substrate. The influence of the W–Ti thin film thickness to its structural and morphological characteristics of a nano-scale were studied. The phase composition and grain size were studied by X- ... ...

    Abstract Thin films were deposited by d.c. sputtering onto a silicon substrate. The influence of the W–Ti thin film thickness to its structural and morphological characteristics of a nano-scale were studied. The phase composition and grain size were studied by X-ray diffraction (XRD), while the surface morphology and surface roughness were determined by scanning tunneling microscopy (STM). The analysis of the phase composition show that the thin films had a polycrystalline structure – they were composed of a b.c.c. Wphase with the presence of a h.c.p. Ti phase. The XRD peak in the scattering angle interval of 38o–43o was interpreted as an overlap of peaks corresponding to the W(110) and Ti(101) planes. The grain size and the mean surface roughness both increase with the thikness of the thin film. The chemical composition of the thin film surface was also analysed by low energy ions scattering (LEIS). The results show the surface segregation of titanium, as well as a substantial presence of oxygen an the surface.
    Keywords PVDW-Ti thin film ; scanning tunnelling microscopy (STM) ; low energy ions scattering (LEIS) ; X-ray diffraction (XRD) ; Chemistry ; QD1-999
    Subject code 530
    Language English
    Publishing date 2006-09-01T00:00:00Z
    Publisher Serbian Chemical Society
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: SIRS score on admission and initial concentration of IL-6 as severe acute pancreatitis outcome predictors.

    Gregoric, Pavle / Pavle, Gregoric / Sijacki, Ana / Ana, Sijacki / Stankovic, Sanja / Sanja, Stankovic / Radenkovic, Dejan / Dejan, Radenkovic / Ivancevic, Nenad / Nenad, Ivancevic / Karamarkovic, Aleksandar / Aleksandar, Karamarkovic / Popovic, Nada / Nada, Popovic / Karadzic, Borivoje / Borivoje, Karadzic / Stijak, Lazar / Stefanovic, Branislav / Branislav, Stefanovic /
    Milosevic, Zoran / Zoran, Milosević / Bajec, Djordje / Djordje, Bajec

    Hepato-gastroenterology

    2010  Volume 57, Issue 98, Page(s) 349–353

    Abstract: Background/aims: Early recognition of severe form of acute pancreatitis is important because these patients need more agressive diagnostic and therapeutical approach an can develope systemic complications such as: sepsis, coagulopathy, Acute Lung Injury ...

    Abstract Background/aims: Early recognition of severe form of acute pancreatitis is important because these patients need more agressive diagnostic and therapeutical approach an can develope systemic complications such as: sepsis, coagulopathy, Acute Lung Injury (ALI), Acute Respiratory Distress Syndrome (ARDS), Multiple Organ Dysfunction Syndrome (MODS), Multiple Organ Failure (MOF). To determine role of the combination of Systemic Inflammatory Response Syndrome (SIRS) score and serum Interleukin-6 (IL-6) level on admission as predictor of illness severity and outcome of Severe Acute Pancreatitis (SAP).
    Methodology: We evaluated 234 patients with first onset of SAP appears in last twenty four hours. A total of 77 (33%) patients died. SIRS score and serum IL-6 concentration were measured in first hour after admission.
    Results: In 105 patients with SIRS score 3 and higher, initial measured IL-6 levels were significantly higher than in the group of remaining 129 patients (72 +/- 67 pg/mL, vs 18 +/- 15 pg/mL). All nonsurvivals were in the first group, with SIRS score 3 and 4 and initial IL-6 concentration 113 +/- 27 pg/mL. The values of C-reactive Protein (CRP) measured after 48h, Acute Physiology and Chronic Health Evaluation (APACHE II) score on admission and Ranson score showed the similar correlation, but serum amylase level did not correlate significantly with Ranson score, IL-6 concentration and APACHE II score.
    Conclusion: The combination of SIRS score on admission and IL-6 serum concentration can be early, predictor of illness severity and outcome in SAP.
    MeSH term(s) Adult ; Aged ; Biomarkers/blood ; C-Reactive Protein/metabolism ; Female ; Humans ; Interleukin-6/blood ; Male ; Middle Aged ; Pancreatitis/blood ; Predictive Value of Tests ; Severity of Illness Index ; Survival Rate ; Systemic Inflammatory Response Syndrome/blood
    Chemical Substances Biomarkers ; Interleukin-6 ; C-Reactive Protein (9007-41-4)
    Language English
    Publishing date 2010-03
    Publishing country Greece
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 801013-4
    ISSN 0172-6390
    ISSN 0172-6390
    Database MEDical Literature Analysis and Retrieval System OnLINE

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