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  1. Article: Abdominal Surgical Emergencies in Patients with Hematological Disorders: An Exacting Experience for Surgeons.

    Nadarajan, Abinaya R / Varghese, Gigi

    Cureus

    2019  Volume 11, Issue 2, Page(s) e4017

    Abstract: Management of surgical emergencies in patients with underlying hematological disorder is challenging due to increased incidence of peri-operative morbidity. We report two cases of abdominal surgical emergencies with pre-existing hematological conditions. ...

    Abstract Management of surgical emergencies in patients with underlying hematological disorder is challenging due to increased incidence of peri-operative morbidity. We report two cases of abdominal surgical emergencies with pre-existing hematological conditions. The first case report is that of a patient diagnosed with pelvic abscess in a previously diagnosed case of Glanzmann's thrombasthenia and the second is a case of intestinal infarction previously diagnosed with paroxysmal nocturnal hemoglobinuria (PNH).
    Language English
    Publishing date 2019-02-05
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.4017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Spectrum of malignant scalp tumours and its impact on management-a tertiary care cancer centre experience.

    Varghese, Bipin T / Nadarajan, Abinaya R / Thomas, Shaji / Iype, Elizabeth Mathew / George, Nebu Abraham / K M, Jagathnath Krishna / Lal, Sahya S / Somanathan, Thara

    World journal of surgical oncology

    2023  Volume 21, Issue 1, Page(s) 330

    Abstract: Background: Tumours on the scalp are diverse and often exhibit site- and histology-specific characteristics. Reconstructing the scalp after oncological resection has always been challenging because of its unique anatomy.: Methodology: A retrospective ...

    Abstract Background: Tumours on the scalp are diverse and often exhibit site- and histology-specific characteristics. Reconstructing the scalp after oncological resection has always been challenging because of its unique anatomy.
    Methodology: A retrospective review of patients with malignant scalp tumour operated on at a single institution over 10 years was performed. Data were collected and analysed regarding the scalp tumour profile, treatment, and the outcome of these procedures.
    Results: Of the 66 patients in our study, 33 (50%) had SCC. In addition to this, 21% were sarcomas, 17% were appendageal carcinomas, 11% were BCCs, and 1% was neuroendocrine carcinoma. Cortical erosion was observed in 6 patients in the CT imaging, all with SCC histology. Among the eight patients with pathological nodal involvement, three had angiosarcoma, three had SCC, one had appendageal carcinoma, and one had neuroendocrine carcinoma. The mean surgical defect size was 67.4 cm
    Conclusion: Scalp tumours are heterogeneous in their clinical profiles. Often, its tumour biology and microscopic extent are underestimated. High suspicion, histological diagnosis, and clear surgical margins are all requirements in successfully treating scalp tumours. In order to minimize morbidity and restore an aesthetic and functional outcome, it is critical to use the simplest scalp reconstruction whenever possible.
    MeSH term(s) Humans ; Scalp/surgery ; Tertiary Healthcare ; Surgical Flaps ; Sarcoma/pathology ; Soft Tissue Neoplasms/pathology ; Carcinoma, Neuroendocrine/pathology ; Retrospective Studies ; Skin Neoplasms/surgery ; Skin Neoplasms/pathology
    Language English
    Publishing date 2023-10-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2118383-1
    ISSN 1477-7819 ; 1477-7819
    ISSN (online) 1477-7819
    ISSN 1477-7819
    DOI 10.1186/s12957-023-03200-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Impact of COVID-19 on Disease Progression and Postoperative Complications in Patients with Head and Neck Cancer.

    Nadarajan, Abinaya R / George, Nebu Abraham / Thomas, Shaji / Varghese, Bipin T / Iype, Elizabeth Mathew / K M, Jagathnath Krishna

    Indian journal of surgical oncology

    2023  , Page(s) 1–5

    Abstract: The COVID-19 pandemic has created a remarkable challenge for the healthcare system. The delayed presentation, diagnosis, and treatment of head and neck cancer during the COVID-19 pandemic is expected to adversely affect outcomes. COVIDSurg collaborative ... ...

    Abstract The COVID-19 pandemic has created a remarkable challenge for the healthcare system. The delayed presentation, diagnosis, and treatment of head and neck cancer during the COVID-19 pandemic is expected to adversely affect outcomes. COVIDSurg collaborative group in 2020 concluded surgery ≥ 4 weeks after a positive COVID-19 swab result was associated with a lower risk of postoperative mortality. The aim of this study is to assess the disease progression due to COVID-19 infection in patients with head and neck cancer planned for surgery and to analyze the postoperative complications in head and neck cancer patients who underwent surgery after COVID-19 infection. This is an ambispective observational study and included patients with head and neck cancer who recovered from COVID-19 infection and underwent surgery from June 2020 to May 2022. There were a total of 1849 patients with head and neck cancer operated in the mentioned study period during COVID-19 pandemic. One hundred fifty-nine patients had documented COVID-19 infection. One hundred two patients had oral cavity carcinoma (64%), and 38 patients had thyroid carcinoma (23.8%). Early disease was noted in 49 patients (30.8%) and locally advanced disease in 108 patients (67.9%). Mean duration of delay in surgery was 4 weeks. Disease progression was noted in 27 patients (17%) out of which 15 patients were inoperable. Thirty-seven out of 159 patients (23%) had postoperative complications, and it included 2 mortality. There was increased trend noted in pulmonary complications and hemorrhage when compared to pre-COVID-19 era. Due to COVID-19 pandemic, delayed elective head and neck cancer surgery has resulted in higher rates of inoperability. COVID-19 has been associated with increased postoperative pulmonary complications and hemorrhage.
    Language English
    Publishing date 2023-06-08
    Publishing country India
    Document type Journal Article
    ZDB-ID 2568289-1
    ISSN 0976-6952 ; 0975-7651
    ISSN (online) 0976-6952
    ISSN 0975-7651
    DOI 10.1007/s13193-023-01779-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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