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  1. Article ; Online: Allergen-specific IgG Antibodies for Cat Allergy?

    Nadeau, Kari C

    American journal of respiratory and critical care medicine

    2021  Volume 204, Issue 1, Page(s) 1–2

    MeSH term(s) Allergens ; Animals ; Cats ; Hypersensitivity ; Immunoglobulin E ; Immunoglobulin G
    Chemical Substances Allergens ; Immunoglobulin G ; Immunoglobulin E (37341-29-0)
    Language English
    Publishing date 2021-04-15
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202103-0662ED
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  2. Article ; Online: Effect of air pollution on asthma.

    Zhou, Xiaoying / Sampath, Vanitha / Nadeau, Kari C

    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology

    2024  Volume 132, Issue 4, Page(s) 426–432

    Abstract: Asthma is a chronic inflammatory airway disease characterized by respiratory symptoms, variable airflow obstruction, bronchial hyperresponsiveness, and airway inflammation. Exposure to air pollution has been linked to an increased risk of asthma ... ...

    Abstract Asthma is a chronic inflammatory airway disease characterized by respiratory symptoms, variable airflow obstruction, bronchial hyperresponsiveness, and airway inflammation. Exposure to air pollution has been linked to an increased risk of asthma development and exacerbation. This review aims to comprehensively summarize recent data on the impact of air pollution on asthma development and exacerbation. Specifically, we reviewed the effects of air pollution on the pathogenic pathways of asthma, including type 2 and non-type 2 inflammatory responses, and airway epithelial barrier dysfunction. Air pollution promotes the release of epithelial cytokines, driving T
    MeSH term(s) Humans ; Air Pollution/adverse effects ; Air Pollution/analysis ; Asthma/etiology ; Asthma/complications ; Air Pollutants/adverse effects ; Air Pollutants/analysis ; Inflammation ; Cytokines ; Pulmonary Disease, Chronic Obstructive
    Chemical Substances Air Pollutants ; Cytokines
    Language English
    Publishing date 2024-01-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1228189-x
    ISSN 1534-4436 ; 0003-4738 ; 1081-1206
    ISSN (online) 1534-4436
    ISSN 0003-4738 ; 1081-1206
    DOI 10.1016/j.anai.2024.01.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Human and planetary health on fire.

    Akdis, Cezmi A / Nadeau, Kari C

    Nature reviews. Immunology

    2022  Volume 22, Issue 11, Page(s) 651–652

    Language English
    Publishing date 2022-08-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 2062776-2
    ISSN 1474-1741 ; 1474-1733
    ISSN (online) 1474-1741
    ISSN 1474-1733
    DOI 10.1038/s41577-022-00776-3
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  4. Article ; Online: Can artificial intelligence (AI) replace oral food challenge?

    Tang, Sindy K Y / Castaño, Nicolas / Nadeau, Kari C / Galli, Stephen J

    The Journal of allergy and clinical immunology

    2024  Volume 153, Issue 3, Page(s) 666–668

    MeSH term(s) Humans ; Artificial Intelligence ; Allergens ; Basophils ; Food ; Food Hypersensitivity/diagnosis
    Chemical Substances Allergens
    Language English
    Publishing date 2024-01-21
    Publishing country United States
    Document type Editorial
    ZDB-ID 121011-7
    ISSN 1097-6825 ; 1085-8725 ; 0091-6749
    ISSN (online) 1097-6825 ; 1085-8725
    ISSN 0091-6749
    DOI 10.1016/j.jaci.2024.01.008
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  5. Article ; Online: Effects of Extreme Weather on Health in Underserved Communities.

    Leap, Sotheany R / Soled, Derek R / Sampath, Vanitha / Nadeau, Kari C

    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology

    2024  

    Abstract: Increased fossil fuel usage has increased CO2 concentrations leading to global warming and climate change with increased frequency and intensity of extreme weather events such as thunderstorms, wildfires, droughts, heat waves, and others. These changes ... ...

    Abstract Increased fossil fuel usage has increased CO2 concentrations leading to global warming and climate change with increased frequency and intensity of extreme weather events such as thunderstorms, wildfires, droughts, heat waves, and others. These changes increase the risk of adverse health effects for all human beings. However, these experiences do not impact everyone equally. Underserved communities, including people of color, the elderly, people living with chronic conditions, and socioeconomically disadvantaged groups have greater vulnerability to the impacts of climate change. These vulnerabilities are a result of multiple factors such as disparities in healthcare, lower educational status, systemic racism, and many others. These social inequities are exacerbated by extreme weather events, which act as threat multipliers increasing disparities in health outcomes. It is clear that without human action, these global temperatures will continue to increase to unbearable levels creating an existential crisis. There is now global consensus that climate change is caused by anthropogenic activity and that actions to mitigate and adapt to climate change are urgently needed. The 2015 Paris Accord was the first truly global commitment that set goals to limit further warming. It also aimed to implement equity in action, founded on the principle of common but differentiated responsibilities. Meeting these goals require individual, community, organizational, national, and global cooperation. Health care professionals, often in the frontline with firsthand knowledge of the health impacts of climate change, can play a key role in advocating for just and equitable climate change adaptation and mitigation.
    Language English
    Publishing date 2024-04-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1228189-x
    ISSN 1534-4436 ; 0003-4738 ; 1081-1206
    ISSN (online) 1534-4436
    ISSN 0003-4738 ; 1081-1206
    DOI 10.1016/j.anai.2024.04.018
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  6. Article ; Online: Climate crisis paralysis: Accelerating global action for health resilience in a changing world.

    Orasche, Jürgen / Nadeau, Kari C / Schuster, Antonia / Rockström, Johan / Akdis, Cezmi A / Traidl-Hoffmann, Claudia

    Allergy

    2024  

    Language English
    Publishing date 2024-03-04
    Publishing country Denmark
    Document type Editorial
    ZDB-ID 391933-x
    ISSN 1398-9995 ; 0105-4538
    ISSN (online) 1398-9995
    ISSN 0105-4538
    DOI 10.1111/all.16096
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  7. Article ; Online: WHO Academy education: globally oriented, multicultural approaches to climate change and health.

    Prats, Elena Villalobos / Neville, Tara / Nadeau, Kari C / Campbell-Lendrum, Diarmid

    The Lancet. Planetary health

    2023  Volume 7, Issue 1, Page(s) e10–e11

    MeSH term(s) Climate Change ; Curriculum ; World Health Organization
    Language English
    Publishing date 2023-01-03
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2542-5196
    ISSN (online) 2542-5196
    DOI 10.1016/S2542-5196(22)00252-2
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  8. Article ; Online: Mechanisms of climate change and related air pollution on the immune system leading to allergic disease and asthma.

    Sampath, Vanitha / Aguilera, Juan / Prunicki, Mary / Nadeau, Kari C

    Seminars in immunology

    2023  Volume 67, Page(s) 101765

    Abstract: Climate change is considered the greatest threat to global health. Greenhouse gases as well as global surface temperatures have increased causing more frequent and intense heat and cold waves, wildfires, floods, drought, altered rainfall patterns, ... ...

    Abstract Climate change is considered the greatest threat to global health. Greenhouse gases as well as global surface temperatures have increased causing more frequent and intense heat and cold waves, wildfires, floods, drought, altered rainfall patterns, hurricanes, thunderstorms, air pollution, and windstorms. These extreme weather events have direct and indirect effects on the immune system, leading to allergic disease due to exposure to pollen, molds, and other environmental pollutants. In this review, we will focus on immune mechanisms associated with allergy and asthma-related health risks induced by climate change events. We will review current understanding of the molecular and cellular mechanisms by which the changing environment mediates these effects.
    MeSH term(s) Climate Change ; Air Pollution ; Asthma/immunology ; Hypersensitivity/immunology ; Immune System ; Disasters ; Humans ; Animals
    Language English
    Publishing date 2023-04-25
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 1018141-6
    ISSN 1096-3618 ; 1044-5323
    ISSN (online) 1096-3618
    ISSN 1044-5323
    DOI 10.1016/j.smim.2023.101765
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  9. Article ; Online: Health implications of the West Virginia v Environmental Protection Agency US Supreme Court decision.

    Kizer, Kenneth W / Perera, Frederica P / Nadeau, Kari C

    The Lancet. Planetary health

    2022  Volume 6, Issue 11, Page(s) e847–e848

    MeSH term(s) Supreme Court Decisions ; United States ; United States Environmental Protection Agency ; West Virginia ; Public Health ; Greenhouse Gases ; Power Plants ; Greenhouse Effect
    Chemical Substances Greenhouse Gases
    Language English
    Publishing date 2022-10-27
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2542-5196
    ISSN (online) 2542-5196
    DOI 10.1016/S2542-5196(22)00249-2
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  10. Article ; Online: World Health Organization global air quality guideline recommendations: Executive summary.

    Goshua, Anna / Akdis, Cezmi A / Nadeau, Kari C

    Allergy

    2022  Volume 77, Issue 7, Page(s) 1955–1960

    Abstract: Air pollution is a leading cause of death globally and has resulted in the loss of millions of healthy years of life. Moreover, the health burden has fallen disproportionately upon people in many low- and middle-income countries, where air quality ... ...

    Abstract Air pollution is a leading cause of death globally and has resulted in the loss of millions of healthy years of life. Moreover, the health burden has fallen disproportionately upon people in many low- and middle-income countries, where air quality continues to deteriorate. To assist authorities and civil society in improving air quality, World Health Organization has published the first global update to its 2005 air quality guidelines based on a significantly improved body of evidence. To facilitate the implementation of the World Health Organization Global Air Quality Guideline recommendations, this article summarizes the purpose and rationale of the quantitative air quality guidelines and interim target levels for six key pollutants: particulate matter 2.5, particulate matter 10, sulfur dioxide, nitrogen dioxide, ozone, and carbon monoxide. In addition, good practice statements are established for the management of pollutants of concern that lack sufficient evidence to substantiate numerical targets.
    MeSH term(s) Air Pollutants/adverse effects ; Air Pollutants/analysis ; Air Pollution/adverse effects ; Air Pollution/analysis ; Humans ; Nitrogen Dioxide/analysis ; Ozone/analysis ; Particulate Matter/adverse effects ; World Health Organization
    Chemical Substances Air Pollutants ; Particulate Matter ; Ozone (66H7ZZK23N) ; Nitrogen Dioxide (S7G510RUBH)
    Language English
    Publishing date 2022-02-08
    Publishing country Denmark
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 391933-x
    ISSN 1398-9995 ; 0105-4538
    ISSN (online) 1398-9995
    ISSN 0105-4538
    DOI 10.1111/all.15224
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