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  1. Book ; Online ; E-Book: Atlas of ocular anatomy

    Ansari, Mohammad Wakeel / Nadeem, Ahmed

    2016  

    Author's details Mohammad Wakeel Ansari, Ahmed Nadeem
    Keywords Auge ; Anatomie
    Subject Mensch ; Tiere ; Tieranatomie ; Kunst der Zergliederung ; Zergliederungskunst ; Sehorgan
    Language English
    Size 1 Online-Ressource (XI, 106 Seiten), Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019441938
    ISBN 978-3-319-42781-2 ; 9783319427805 ; 3-319-42781-4 ; 3319427806
    DOI 10.1007/978-3-319-42781-2
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Point mutations in the gene encoding IP3 receptor subtype 3 cause impairment in T-cell and B-cell immune responses via dysfunctional Ca

    Nadeem, Ahmed / Ahmad, Sheikh F

    Cellular & molecular immunology

    2023  Volume 20, Issue 2, Page(s) 214–216

    MeSH term(s) Point Mutation ; Inositol 1,4,5-Trisphosphate Receptors/genetics ; Inositol 1,4,5-Trisphosphate Receptors/metabolism ; T-Lymphocytes/metabolism ; Calcium/metabolism
    Chemical Substances Inositol 1,4,5-Trisphosphate Receptors ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2023-01-04
    Publishing country China
    Document type Letter ; Comment
    ZDB-ID 2435097-7
    ISSN 2042-0226 ; 1672-7681
    ISSN (online) 2042-0226
    ISSN 1672-7681
    DOI 10.1038/s41423-022-00938-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: An electronic health record system implementation in a resource limited country-lessons learned.

    Ali, Sayed K / Khan, Haroon / Shah, Jasmit / Nadeem Ahmed, K

    Digital health

    2023  Volume 9, Page(s) 20552076231203660

    Abstract: Electronic health records have revolutionized the medical world by improving medical care, refining provider documentation, standardizing care, and minimizing sentinel events. Successful implementation of electronic health records remains a daunting task ...

    Abstract Electronic health records have revolutionized the medical world by improving medical care, refining provider documentation, standardizing care, and minimizing sentinel events. Successful implementation of electronic health records remains a daunting task and requires careful strategic planning and buy-in from key stakeholders. Much has been published in resource-rich settings and high-income countries about implementations of electronic health records. However, little is known about the experience in resource-limited settings where challenges remain unique and distinct from other parts of the world. Our intention is to share lessons learned during implementation of a web-based electronic health record at a tertiary care center in Kenya.
    Language English
    Publishing date 2023-09-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2819396-9
    ISSN 2055-2076
    ISSN 2055-2076
    DOI 10.1177/20552076231203660
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Prediction of deleterious non-synonymous SNPs of TMPRSS2 protein combined with Molecular Dynamics Simulations and free energy analysis to identify the potential peptide substrates against SARS-CoV-2.

    Ramachandran, Balajee / Nadeem, Ahmed / Mohanprasanth, Aruchamy / Saravanan, Muthupandian

    Journal of biomolecular structure & dynamics

    2024  , Page(s) 1–15

    Abstract: Globally the SARS-CoV-2 viral infection demands for the new drugs, the TMPRSS2 target plays a vital role in facilitating the virus entry. The aim of the present study is to identify the potential peptide substrate from the Anti-viral database against ... ...

    Abstract Globally the SARS-CoV-2 viral infection demands for the new drugs, the TMPRSS2 target plays a vital role in facilitating the virus entry. The aim of the present study is to identify the potential peptide substrate from the Anti-viral database against TMPRSS2 of SARS-CoV-2. The compound screening and variation analysis were performed using molecular docking analysis and online tools such as PROVEAN and SNAP2 server, respectively. The re-docked crystal structure peptide substrate exhibits -128.151 kcal/mol whereas the RRKK peptide substrate shows -134.158 kcal/mol. Further, the selected compounds were proceeded with Molecular Dynamics Simulation, it explores the stability of the complex by revealing the hotspot residues (His296 and Ser441) were active for nucleophilic attack against TMPRSS2. The average Binding Free Energy values computed through MM/GBSA for RRKK, Camostat, and Crystal Structure were shown -69.9278 kcal/mol, -64.5983 kcal/mol, and -63.9755 kcal/mol, respectively against TMPRSS2. The 'rate of acylation' emerges as an indicator for RRKK's efficacy, it maintains the distance of 3.2 Å with Ser441 resembles, whilst its -NH backbone stabilizes at 2.5 Å 'Michaelis Complex' which leads to prevent the entry of SARS-CoV-2 to human cells. The sequence variation analysis explores that the V160 and G6 substitutions are essential to emphasize the uncover possibilities for the ongoing drug discovery research. Therefore, the identified peptide substrate found to be potent against SARS-CoV-2 and these results will be valuable for ongoing drug discovery research.Communicated by Ramaswamy H. Sarma.
    Language English
    Publishing date 2024-04-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 49157-3
    ISSN 1538-0254 ; 0739-1102
    ISSN (online) 1538-0254
    ISSN 0739-1102
    DOI 10.1080/07391102.2024.2330710
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Maisotsenko Cycle for Heat Recovery in Gas Turbines

    Rasikh Tariq / Hakan Caliskan / Nadeem Ahmed Sheikh

    Global Challenges, Vol 7, Iss 11, Pp n/a-n/a (2023)

    A Fundamental Thermodynamic Assessment

    2023  

    Abstract: Abstract This paper reports the Maisotsenko's cycle‐based waste heat recovery system with enhanced humidification to exploit the maximum waste heat recovery potential of the gas turbine. This research uses an integrated methodology coupling thermodynamic ...

    Abstract Abstract This paper reports the Maisotsenko's cycle‐based waste heat recovery system with enhanced humidification to exploit the maximum waste heat recovery potential of the gas turbine. This research uses an integrated methodology coupling thermodynamic balances with heat transfer model of air saturator. The performance of the system is deduced which are assisted with sensitivity analysis indicating the optimal mass flow rate ratio (0.7–0.8) and pressure ratio (4.5–5.0) between the topping and bottoming cycles, and the air saturator split (extraction) ratio (0.5). The net‐work output, energy, and exergy efficiencies of the system are found to be ≈58.39 MW, ≈55.85%, and ≈52.79%, respectively. The maximum exergy destruction ratios are found as 68.2% for the combustion chamber, 16.0% for the topping turbine, 5.7% for topping compressor, 4.9% air saturator. The integration of Maisotsenko's cycle‐based waste heat recovery system with a comprehensive thermodynamic model, as demonstrated in this research, offers valuable insights into enhancing the efficiency, cost‐effectiveness, and environmental impact of gas turbines. By presenting fundamental equations related to thermodynamic balances, this work serves as an invaluable educational resource, equipping future researchers and students with the knowledge and skills needed to advance the study of thermodynamics and sustainable energy solutions.
    Keywords educational innovation ; exergy analysis ; gas turbines ; maisotsenko cycle ; waste heat recovery ; Technology ; T ; Environmental sciences ; GE1-350
    Subject code 690
    Language English
    Publishing date 2023-11-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Incidental Detection of Adrenal Myelolipoma in a middle age female patient

    Muhammad Nadeem Ahmed Khan / Shaheena Begum

    Liaquat National Journal of Primary Care, Vol 5, Iss 2, Pp 123-

    a case report

    2023  Volume 125

    Abstract: Adrenal myelolipoma is a rare benign neoplastic lesion, mostly asymptomatic and unilateral. It originates from the adrenal gland and is made up of mature adipose tissues with the hematopoietic series. Adrenal lipomas are extremely rare and always benign ... ...

    Abstract Adrenal myelolipoma is a rare benign neoplastic lesion, mostly asymptomatic and unilateral. It originates from the adrenal gland and is made up of mature adipose tissues with the hematopoietic series. Adrenal lipomas are extremely rare and always benign and non-secreting. We describe a case of a hypertensive female patient who presented with abdominal pain. Physical examination and investigations were unremarkable. Ultrasound abdomen showed a hyperechoic mass on the left side of the abdomen. Contrastenhanced abdomen illustrated a large heterogeneous mix density lesion in the left suprarenal gland showing enhancing soft tissue and macroscopic fat components suggesting adrenal myelolipoma. Although the patient did not have any related complications but owing to the large size of the tumor, surgical resection was planned which was later done successfully
    Keywords myelolipoma ; adrenal gland ; lipoma ; Medicine (General) ; R5-920
    Subject code 630
    Language English
    Publishing date 2023-08-01T00:00:00Z
    Publisher Liaquat National Hospital and Medical College
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: KNOWLEDGE, ATTITUDE AND PRACTICE SURVEY REGARDING NOISE-INDUCED HEARING LOSS IN AIR AND GROUND CREW OF PAKISTAN AIR FORCE BASE MASROOR

    Nadeem Ahmed Sheikh

    Pakistan Armed Forces Medical Journal, Vol 69, Iss 4, Pp 742-

    2019  Volume 747

    Abstract: Objectives: To assess the pattern of knowledge, attitude and practice regarding occupational noise-induced hearing loss, amongst the air and ground crew of Pakistan Air Force Base Masroor, Karachi. Study Design: KAP survey. Place and Duration of Study: ... ...

    Abstract Objectives: To assess the pattern of knowledge, attitude and practice regarding occupational noise-induced hearing loss, amongst the air and ground crew of Pakistan Air Force Base Masroor, Karachi. Study Design: KAP survey. Place and Duration of Study: Department of ENT, PAF Hospital Masroor, Karachi; and Flight Surgeon’s Inspection Room, PAF Base Masroor, Karachi. The study was conducted from January 2016 till October 2016. Patients and Methods: 137 aviation personnel who worked for 6 to 8 hours on a weekday; 5 days a week, in an ambient noise greater than 95dB SPL were requested to respond to constructs of a specially modified valid questionnaire. Results: Only weak areas in knowledge section were awareness about appearance of early indication of noise induced hearing loss and a misunderstanding regarding medical cure of the disorder. Precise comprehension, attitude and practices were attributed to literate background and high standard of professional training of individuals in the organization. Conclusion: Realization of understanding the risks and setting up correct practical approach by following technical guidelines and adopting counteractive measures ensure wellness of individuals and their outright efficacy at workplace.
    Keywords hearing loss ; occupational noise ; Medicine ; R ; Medicine (General) ; R5-920
    Language English
    Publishing date 2019-08-01T00:00:00Z
    Publisher Army Medical College Rawalpindi
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: A systematic review of simulation training for lower extremity bypass procedures.

    Siddiqui, Nadeem Ahmed / Javed, Aden / Pirzada, Ammar

    Vascular

    2023  , Page(s) 17085381231192689

    Abstract: Objectives: Simulation is used across surgical specialties for skill enhancement. The choice and assessment method of a simulator varies across literature. In the age of endovascular approach, trainees have limited exposure to open lower limb bypass ... ...

    Abstract Objectives: Simulation is used across surgical specialties for skill enhancement. The choice and assessment method of a simulator varies across literature. In the age of endovascular approach, trainees have limited exposure to open lower limb bypass procedures which needs attention. This review aims to assess the utility of simulation training in lower limb bypass surgery using Kirkpatrick's model.
    Methods: Using PRISMA statement, we included all the studies done on simulators in lower limb bypass surgical procedures for this systematic review. The primary outcome was to assess the effectiveness of different types of simulation used for lower limb bypass surgery using the Kirkpatrick's model for training evaluation.
    Results: An initial search identified 295 articles out of which 7 articles were found to be eligible for this systematic review. A variety of simulators were used including cadavers and synthetic models. Most studies (
    Conclusion: Most of the existing studies are at level 2 of Kirkpatrick's model which reflects learning changes in trainees after simulation. Feedback mechanism needs to be evolved where the improvement after simulation training can be gauged by its replication in clinical practice and improved patient care practices corresponding to the highest level of Kirkpatrick's model.
    Language English
    Publishing date 2023-07-26
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2137151-9
    ISSN 1708-539X ; 1708-5381
    ISSN (online) 1708-539X
    ISSN 1708-5381
    DOI 10.1177/17085381231192689
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Maisotsenko Cycle for Heat Recovery in Gas Turbines: A Fundamental Thermodynamic Assessment.

    Tariq, Rasikh / Caliskan, Hakan / Sheikh, Nadeem Ahmed

    Global challenges (Hoboken, NJ)

    2023  Volume 7, Issue 11, Page(s) 2300178

    Abstract: This paper reports the Maisotsenko's cycle-based waste heat recovery system with enhanced humidification to exploit the maximum waste heat recovery potential of the gas turbine. This research uses an integrated methodology coupling thermodynamic balances ...

    Abstract This paper reports the Maisotsenko's cycle-based waste heat recovery system with enhanced humidification to exploit the maximum waste heat recovery potential of the gas turbine. This research uses an integrated methodology coupling thermodynamic balances with heat transfer model of air saturator. The performance of the system is deduced which are assisted with sensitivity analysis indicating the optimal mass flow rate ratio (0.7-0.8) and pressure ratio (4.5-5.0) between the topping and bottoming cycles, and the air saturator split (extraction) ratio (0.5). The net-work output, energy, and exergy efficiencies of the system are found to be ≈58.39 MW, ≈55.85%, and ≈52.79%, respectively. The maximum exergy destruction ratios are found as 68.2% for the combustion chamber, 16.0% for the topping turbine, 5.7% for topping compressor, 4.9% air saturator. The integration of Maisotsenko's cycle-based waste heat recovery system with a comprehensive thermodynamic model, as demonstrated in this research, offers valuable insights into enhancing the efficiency, cost-effectiveness, and environmental impact of gas turbines. By presenting fundamental equations related to thermodynamic balances, this work serves as an invaluable educational resource, equipping future researchers and students with the knowledge and skills needed to advance the study of thermodynamics and sustainable energy solutions.
    Language English
    Publishing date 2023-10-15
    Publishing country Germany
    Document type Journal Article
    ISSN 2056-6646
    ISSN (online) 2056-6646
    DOI 10.1002/gch2.202300178
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Role of stem cells in arteriovenous access: perspective from Lower Middle Income Countries.

    Siddiqui, Nadeem Ahmed / Javed, Aden / Raja, Ahsan Raza

    JPMA. The Journal of the Pakistan Medical Association

    2023  Volume 73Suppl 1, Issue 2, Page(s) S160–S163

    Abstract: Adequately created well functional haemodialysis access is an important part for the physical and mental wellbeing of renal failure patients. Every effort should be made to enhance the patency of these accesses. Recently, stem cell treatment modalities ... ...

    Abstract Adequately created well functional haemodialysis access is an important part for the physical and mental wellbeing of renal failure patients. Every effort should be made to enhance the patency of these accesses. Recently, stem cell treatment modalities have opened new avenues in the better patency of arteriovenous fistula. Use of mesenchymal stromal cells (MSC) to prevent venous neointimal hyperplasia have been studied with good success rates. Adopting such costly treatment modalities in low middle income class country like Pakistan is associated with significant challenges. This short report discusses the current role of stem cells in arteriovenous access and how this exciting modality can be utilized in our country.
    MeSH term(s) Humans ; Arteriovenous Shunt, Surgical ; Vascular Patency ; Developing Countries ; Risk Factors ; Renal Dialysis ; Stem Cells ; Treatment Outcome ; Retrospective Studies
    Language English
    Publishing date 2023-02-14
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 603873-6
    ISSN 0030-9982
    ISSN 0030-9982
    DOI 10.47391/JPMA.AKUS-26
    Database MEDical Literature Analysis and Retrieval System OnLINE

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