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  1. Article ; Online: Amyloidosis and the Kidney: An Update.

    Nader, Ralph / Angel-Korman, Avital / Havasi, Andrea

    Seminars in nephrology

    2023  Volume 42, Issue 6, Page(s) 151343

    Abstract: Various types of systemic amyloidosis can wreak havoc on the architecture and functioning of the kidneys. Amyloidosis should be suspected in patients with worsening kidney function, proteinuria, and multisystem involvement, but isolated kidney ... ...

    Abstract Various types of systemic amyloidosis can wreak havoc on the architecture and functioning of the kidneys. Amyloidosis should be suspected in patients with worsening kidney function, proteinuria, and multisystem involvement, but isolated kidney involvement also is possible. Confirming the amyloidosis type and specific organ dysfunction is of paramount importance to select the appropriately tailored treatment and aim for better survival while avoiding treatment-associated toxicities. Amyloid renal staging in light chain amyloidosis amyloidosis helps inform prognosis and risk for end-stage kidney disease. Biomarker-based staging systems and response assessment guide the therapeutic strategy and allow the timely identification of refractory or relapsing disease so that patients can be switched to salvage therapy. Kidney transplantation is a viable option for selected patients with amyloidosis. Because of the complex nature of the pathophysiology and treatment of amyloidosis, a multidisciplinary team-based approach should be used in the care of these patients.
    MeSH term(s) Humans ; Kidney ; Amyloidosis/therapy ; Kidney Transplantation/adverse effects ; Kidney Failure, Chronic ; Proteinuria/etiology
    Language English
    Publishing date 2023-05-04
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 604652-6
    ISSN 1558-4488 ; 0270-9295
    ISSN (online) 1558-4488
    ISSN 0270-9295
    DOI 10.1016/j.semnephrol.2023.151343
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Unsafe at any speed: the designed-in dangers of the American automobile. 1965.

    Nader, Ralph

    American journal of public health

    2011  Volume 101, Issue 2, Page(s) 254–256

    MeSH term(s) Automobiles ; Consumer Advocacy/history ; History, 20th Century ; Humans ; Politics ; Public Health/history ; Risk Assessment
    Language English
    Publishing date 2011-01-12
    Publishing country United States
    Document type Biography ; Classical Article ; Historical Article ; Journal Article ; Portrait
    ZDB-ID 121100-6
    ISSN 1541-0048 ; 0090-0036 ; 0002-9572
    ISSN (online) 1541-0048
    ISSN 0090-0036 ; 0002-9572
    DOI 10.2105/ajph.101.2.254
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online: Unstoppable

    Nader, Ralph

    The Emerging Left-Right Alliance to Dismantle the Corporate State

    2014  

    Abstract: Ralph Nader has fought for over fifty years on behalf of American citizens against the reckless influence of corporations and their government patrons on our society. Now he ramps up the fight and makes a persuasive case that Americans are not powerless. ...

    Abstract Ralph Nader has fought for over fifty years on behalf of American citizens against the reckless influence of corporations and their government patrons on our society. Now he ramps up the fight and makes a persuasive case that Americans are not powerless. In Unstoppable, he explores the emerging political alignment of the Left and the Right against converging corporate-government tyranny.Large segments from the progressive, conservative, and libertarian political camps find themselves aligned in opposition to the destruction of civil liberties, the economically draining corporate welfare state
    Language English
    Size Online-Ressource (241 p)
    Publisher Nation Books
    Publishing place New York
    Document type Book ; Online
    Note Description based upon print version of record
    ISBN 9781568584546 ; 1568584547
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  4. Book: Getting steamed to overcome corporatism

    Nader, Ralph

    build it together to win

    2011  

    Author's details Ralph Nader
    Keywords Corporate state
    Language English
    Size 201 S, 23 cm
    Edition 2. print
    Publisher Common Courage Press
    Publishing place Monroe, Me
    Document type Book
    Note Includes index
    ISBN 1567514065 ; 1567514073 ; 9781567514063 ; 9781567514070
    Database Former special subject collection: coastal and deep sea fishing

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  5. Book ; Online: Corporate Welfare

    Bennett, James T / Nader, Ralph

    Crony Capitalism That Enriches the Rich

    2015  

    Keywords Subsidies - United States
    Language English
    Size 1 Online-Ressource (239 pages)
    Edition 1st ed
    Document type Book ; Online
    ISBN 9781351525732 ; 9781412855983 ; 9781412855983 ; 1351525735 ; 1412855985 ; 1412855985
    Database ECONomics Information System

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  6. Article: Arnold imitates art.

    Nader, Ralph

    Revolution (Oakland, Calif.)

    2005  Volume 6, Issue 2, Page(s) 7–8

    MeSH term(s) California ; Health Policy/legislation & jurisprudence ; Humans ; Labor Unions/organization & administration ; Mass Media ; Nursing Staff, Hospital/legislation & jurisprudence ; Nursing Staff, Hospital/supply & distribution ; Personnel Staffing and Scheduling/legislation & jurisprudence ; Politics
    Language English
    Publishing date 2005-03
    Publishing country United States
    Document type Journal Article
    ISSN 1059-0927
    ISSN 1059-0927
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Predictors and outcomes of acute kidney injury during autologous stem cell transplantation in AL amyloidosis.

    Nader, Ralph / Zhen, Aileen / Angel-Korman, Avital / Pavlovich, Stephanie S / Pogrebinsky, Alexander / Doros, Gheorghe / Menn-Josephy, Hanni / Stern, Lauren / Sanchorawala, Vaishali / Havasi, Andrea

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    2021  Volume 37, Issue 7, Page(s) 1281–1288

    Abstract: Background: Acute kidney injury (AKI) is a common complication after high-dose melphalan and autologous stem cell transplantation (HDM/SCT) in patients with light chain (AL) amyloidosis. However, its incidence, predictors and outcomes are not well known. ...

    Abstract Background: Acute kidney injury (AKI) is a common complication after high-dose melphalan and autologous stem cell transplantation (HDM/SCT) in patients with light chain (AL) amyloidosis. However, its incidence, predictors and outcomes are not well known.
    Methods: This observational study included 223 patients with AL amyloidosis who underwent HDM/SCT. AKI was defined as an increase in serum creatinine to ≥1.5 times the baseline occurring within the first 30 days of HDM/SCT.
    Results: The median age was 58 years (range: 30-77). Kidney and cardiac involvement were present in 86.1% and 56.8%, respectively. The median estimated glomerular filtration rate (eGFR) was 83.5 mL/min/1.73 m2 (range: 9-213) and proteinuria was 2899 mg/day (range: 0-19 966). AKI occurred in 29.1% of patients. Dialysis was initiated in 15 patients (6.7%) and of these 12 (80%) were able to discontinue dialysis. Most of the episodes of AKI occurred within the first 2 weeks; with a median follow-up of 4.5 years (range: 0.1-16.5), AKI was associated with increased overall mortality [hazard rato (HR) = 4.53, 95% confidence interval (CI) 2-10.23]. The 10-year overall survival was 87.1% without AKI, versus 56.9% with AKI. AKI was also associated with an increased risk for end-stage kidney disease (ESKD) (HR = 4.6, 95% CI 1.44-14.38). The risk of developing ESKD at 10 years was 18.9% with AKI, versus 8.1% without AKI. Several risk factors were found and using multivariate logistic regression, a prediction model was developed that included three readily available variables: eGFR <60 mL/min/1.73 m2, interventricular septal thickness in diastole >12 mm and albumin <3 g/dL. This model was able to predict AKI development with an area under the curve of 0.8.
    Conclusions: AKI is common in the post-HDM/SCT period and it leads to increased risk for ESKD and death. Our prediction model is an easily deployable tool in clinical settings as part of the discussion with patients who are being prepared for HDM/SCT.
    MeSH term(s) Acute Kidney Injury/complications ; Acute Kidney Injury/etiology ; Amyloidosis/complications ; Hematopoietic Stem Cell Transplantation/adverse effects ; Humans ; Immunoglobulin Light-chain Amyloidosis/complications ; Immunoglobulin Light-chain Amyloidosis/therapy ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/therapy ; Melphalan ; Middle Aged ; Renal Dialysis ; Retrospective Studies ; Risk Factors ; Transplantation, Autologous/adverse effects
    Chemical Substances Melphalan (Q41OR9510P)
    Language English
    Publishing date 2021-05-27
    Publishing country England
    Document type Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 90594-x
    ISSN 1460-2385 ; 0931-0509
    ISSN (online) 1460-2385
    ISSN 0931-0509
    DOI 10.1093/ndt/gfab189
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2198: Show issues Location:
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    Zs.MO 329: Show issues

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  8. Book: The case against "free trade"

    Nader, Ralph

    GATT, NAFTA, and the globalization of corporate power

    1993  

    Institution General Agreement on Tariffs and Trade (Organization)
    Author's details Ralph Nader
    Keywords Free trade ; International trade
    Language English
    Size 230 S., 21 cm
    Publisher Earth Island Press
    Publishing place San Francisco, Calif. u.a.
    Document type Book
    ISBN 1556431694 ; 9781556431692
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  9. Book: The case against free trade

    Nader, Ralph

    GATT, NAFTA, and the globalization of corporate power

    1993  

    Author's details Ralph Nader
    Keywords Handelsliberalisierung ; Internationale Wirtschaftspolitik ; Nachhaltige Entwicklung ; Welt ; 14*24*34
    Language English
    Size 230 S
    Document type Book
    Note Enth. 15 Beitr.
    ISBN 1556431694 ; 9781556431692
    Database ECONomics Information System

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  10. Book: Cutting corporate welfare

    Nader, Ralph

    (The open media pamphlet series ; 18)

    2000  

    Author's details Ralph Nader; foreword by Winona LaDuke
    Series title The open media pamphlet series ; 18
    Keywords Subvention ; USA
    Language Undetermined
    Size 141 S, 18 cm
    Edition Seven Stories Press 1. ed
    Publisher Seven Stories Press
    Publishing place New York
    Document type Book
    Note Includes bibliographical references (p. 127-133)
    ISBN 158322033X ; 9781583220337
    Database ECONomics Information System

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