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  1. Article ; Online: Optical Fiber Sensors for Rapid Screening of COVID-19.

    Nag, Pooja / Sadani, Kapil / Mukherji, Soumyo

    Transactions of the Indian National Academy of Engineering : an international journal of engineering and technology

    2020  Volume 5, Issue 2, Page(s) 233–236

    Abstract: Rapid diagnosis of coronavirus disease COVID-19 is challenging in developing countries due to diverse clinical presentations and limited healthcare infrastructure. Biosensors hold immense prospects for diagnosis of the disease. Two approaches are ... ...

    Abstract Rapid diagnosis of coronavirus disease COVID-19 is challenging in developing countries due to diverse clinical presentations and limited healthcare infrastructure. Biosensors hold immense prospects for diagnosis of the disease. Two approaches are proposed: the first involves measurement of host immune response and second, the detection of viruses or viral cell surface proteins using suitable bioreceptors. The article provides an overview of evanescent wave absorbance and localized surface plasmon resonance-based optic fiber platform for potential screening of COVID-19.
    Language English
    Publishing date 2020-06-19
    Publishing country Singapore
    Document type Journal Article
    ISSN 2662-5423
    ISSN (online) 2662-5423
    DOI 10.1007/s41403-020-00128-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Evanescent Wave Optical Fiber Sensors Using Enzymatic Hydrolysis on Nanostructured Polyaniline for Detection of β-Lactam Antibiotics in Food and Environment.

    Nag, Pooja / Sadani, Kapil / Mohapatra, Sanjeeb / Mukherji, Suparna / Mukherji, Soumyo

    Analytical chemistry

    2021  Volume 93, Issue 4, Page(s) 2299–2308

    Abstract: β-Lactam antibiotics such as penicillins and cephalosporins are extensively used for human infection therapy. Consistent unintended exposure to these antibiotics via food and water is known to promote antibiotic-resistant bacterial pathogenesis with high ...

    Abstract β-Lactam antibiotics such as penicillins and cephalosporins are extensively used for human infection therapy. Consistent unintended exposure to these antibiotics via food and water is known to promote antibiotic-resistant bacterial pathogenesis with high morbidity and mortality in humans. An optical enzymatic biosensor for rapid and point-of-use detection of these antibiotics in food and water has been developed and tested. Enzymatic hydrolysis of β-lactams, on the electroactive polyaniline nanofibers, altered the polymeric backbone of the nanofibers, from emeraldine base form to emeraldine salt, which was measured as an increase in evanescent wave absorbance at 435 nm. The sensors were calibrated by spiking antibiotic-free milk with ceftazidime (as a model β-lactam analyte) in a linear range of 0.36-3600 nM (
    MeSH term(s) Aniline Compounds/chemistry ; Animals ; Anti-Bacterial Agents/chemistry ; Chickens ; Drug Residues/chemistry ; Environmental Monitoring/methods ; Environmental Pollutants/chemistry ; Food Contamination ; Hydrolysis ; Meat/analysis ; Milk/chemistry ; Molecular Structure ; Nanostructures ; Optical Fibers ; Waste Water/chemistry ; beta-Lactams/chemistry
    Chemical Substances Aniline Compounds ; Anti-Bacterial Agents ; Environmental Pollutants ; Waste Water ; beta-Lactams ; polyaniline
    Language English
    Publishing date 2021-01-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1508-8
    ISSN 1520-6882 ; 0003-2700
    ISSN (online) 1520-6882
    ISSN 0003-2700
    DOI 10.1021/acs.analchem.0c04169
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: LSPR based optical fiber sensor with chitosan capped gold nanoparticles on BSA for trace detection of Hg (II) in water, soil and food samples.

    Sadani, Kapil / Nag, Pooja / Mukherji, Soumyo

    Biosensors & bioelectronics

    2019  Volume 134, Page(s) 90–96

    Abstract: Mercury is a diversely bioaccumulating heavy metal pollutant toxic to all life forms. In this work, an optical biosensor has been developed and calibrated for universal detection and quantification of mercuric ions, in the range 0.1-540 parts per billion, ...

    Abstract Mercury is a diversely bioaccumulating heavy metal pollutant toxic to all life forms. In this work, an optical biosensor has been developed and calibrated for universal detection and quantification of mercuric ions, in the range 0.1-540 parts per billion, in biological and environmental samples. Chitosan capped gold nanoparticles on bovine serum albumin are proposed as an ultrasensitive plasmonic mercury receptor on U-bend optical fiber platform. The sensor was calibrated and tested with tap water, sewage contaminated water, marine water, long lived sea fish tissue, fossil fuel fly ash contaminated soil and vegetable samples. The sensor performance was validated with real samples inherently containing mercury. Overall standard error of less than 15% and a coefficient of variation less than 12% (n = 3) was found across all samples, indicating good fitness for diverse usage. Experimentally determined limit of detection of mercuric ions was 0.1 parts per billion in tap water (twenty times lesser than the Environment protection agency limit of 2 parts per billion in drinking water) and 0.2 parts per billion in sea fish and vegetable samples with negligible cross sensitivity towards other metal ions.
    MeSH term(s) Animals ; Cattle ; Chitosan/chemistry ; Drinking Water/analysis ; Equipment Design ; Food Analysis/instrumentation ; Food Contamination/analysis ; Gold/chemistry ; Immobilized Proteins/chemistry ; Limit of Detection ; Mercury/analysis ; Nanoparticles/chemistry ; Seafood/analysis ; Serum Albumin, Bovine/chemistry ; Soil/chemistry ; Soil Pollutants/analysis ; Surface Plasmon Resonance/instrumentation ; Vegetables/chemistry ; Water Pollutants, Chemical/analysis
    Chemical Substances Drinking Water ; Immobilized Proteins ; Soil ; Soil Pollutants ; Water Pollutants, Chemical ; Serum Albumin, Bovine (27432CM55Q) ; Gold (7440-57-5) ; Chitosan (9012-76-4) ; Mercury (FXS1BY2PGL)
    Language English
    Publishing date 2019-03-22
    Publishing country England
    Document type Evaluation Studies ; Journal Article
    ZDB-ID 1011023-9
    ISSN 1873-4235 ; 0956-5663
    ISSN (online) 1873-4235
    ISSN 0956-5663
    DOI 10.1016/j.bios.2019.03.046
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Optical Fiber Sensors for Rapid Screening of COVID-19

    Nag, Pooja / Sadani, Kapil / Mukherji, Soumyo

    Transactions of the Indian National Academy of Engineering

    Abstract: Rapid diagnosis of coronavirus disease COVID-19 is challenging in developing countries due to diverse clinical presentations and limited healthcare infrastructure Biosensors hold immense prospects for diagnosis of the disease Two approaches are proposed: ...

    Abstract Rapid diagnosis of coronavirus disease COVID-19 is challenging in developing countries due to diverse clinical presentations and limited healthcare infrastructure Biosensors hold immense prospects for diagnosis of the disease Two approaches are proposed: the first involves measurement of host immune response and second, the detection of viruses or viral cell surface proteins using suitable bioreceptors The article provides an overview of evanescent wave absorbance and localized surface plasmon resonance-based optic fiber platform for potential screening of COVID-19
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #608527
    Database COVID19

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  5. Article ; Online: Optical Fiber Sensors for Rapid Screening of COVID-19

    Nag, Pooja / Sadani, Kapil / Mukherji, Soumyo

    Transactions of the Indian National Academy of Engineering

    2020  Volume 5, Issue 2, Page(s) 233–236

    Keywords covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ISSN 2662-5415
    DOI 10.1007/s41403-020-00128-4
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Polyphenol stabilized copper nanoparticle formulations for rapid disinfection of bacteria and virus on diverse surfaces.

    Sadani, Kapil / Nag, Pooja / Pisharody, Lakshmi / Thian, Xiao Yun / Bajaj, Geetika / Natu, Gayatri / Mukherji, Suparna / Mukherji, Soumyo

    Nanotechnology

    2021  Volume 33, Issue 3

    Abstract: Rapid and sustained disinfection of surfaces is necessary to check the spread of pathogenic microbes. The current study proposes a method of synthesis and use of copper nanoparticles (CuNPs) for contact disinfection of pathogenic microorganisms. ... ...

    Abstract Rapid and sustained disinfection of surfaces is necessary to check the spread of pathogenic microbes. The current study proposes a method of synthesis and use of copper nanoparticles (CuNPs) for contact disinfection of pathogenic microorganisms. Polyphenol stabilized CuNPs were synthesized by successive reductive disassembly and reassembly of copper phenolic complexes. Morphological and compositional characterization by transmission electron microscope (TEM), selected area diffraction and electron energy loss spectroscopy revealed monodispersed spherical (
    MeSH term(s) Bacteria/classification ; Bacteria/drug effects ; Coated Materials, Biocompatible/pharmacology ; Copper/chemistry ; Disinfectants/chemical synthesis ; Disinfectants/chemistry ; Disinfectants/pharmacology ; Disinfection/methods ; Metal Nanoparticles/chemistry ; Microbial Sensitivity Tests ; Polyphenols/chemistry ; Virus Inactivation/drug effects ; Viruses/classification ; Viruses/drug effects
    Chemical Substances Coated Materials, Biocompatible ; Disinfectants ; Polyphenols ; Copper (789U1901C5)
    Language English
    Publishing date 2021-10-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362365-5
    ISSN 1361-6528 ; 0957-4484
    ISSN (online) 1361-6528
    ISSN 0957-4484
    DOI 10.1088/1361-6528/ac2e77
    Database MEDical Literature Analysis and Retrieval System OnLINE

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