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Article: Cutaneous & subcutaneous phaeohyphomycosis by

Nag, Soumyabrata / Marak, Rungmei S K

2022 Volume 152, Issue Suppl 1, Page(s) S175–S176

MeSH term(s)	Administration, Cutaneous ; Ascomycota ; Humans ; Phaeohyphomycosis/diagnosis ; Skin
Language	English
Publishing date	2022-03-08
Publishing country	India
Document type	Journal Article
ZDB-ID	390883-5
ISSN	0971-5916 ; 0019-5340
ISSN	0971-5916 ; 0019-5340
DOI	10.4103/ijmr.IJMR_2270_19
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Peri-prosthetic Joint Infection due to Candida albicans in a Young Immunocompetent Patient - A Rare Case Report.

Tiwari, Vivek / Shendre, Pooja / Nag, Soumyabrata / Mishra, Meena / Roy, Mainak / Dwidmuthe, Samir

Journal of orthopaedic case reports

2024 Volume 14, Issue 2, Page(s) 160–164

Abstract: Introduction: The recent surge in joint replacement surgeries in India, particularly total knee and hip replacements, is notable. The majority of patients undergoing these procedures suffered from knee osteoarthritis or femoral head avascular necrosis. ... ...

Abstract	Introduction: The recent surge in joint replacement surgeries in India, particularly total knee and hip replacements, is notable. The majority of patients undergoing these procedures suffered from knee osteoarthritis or femoral head avascular necrosis. However, this increase in joint replacements has also led to a rise in periprosthetic joint infections (PJI), a severe and costly complication. PJI is responsible for 25% of total knee arthroplasty failures and 15% of total hip arthroplasty failures. Various risk factors, such as diabetes, fractures, and arthritis, are associated with PJI development. Bacterial infections, notably Staphylococcus species, are the primary cause of PJI, but rare fungal infections are often caused by Candida and Aspergillus. There is a lack of clinical trials and limited knowledge about the prevalence and treatment of fungal PJIs. Case report: This report presents a unique case of delayed PJI caused by Candida albicans in an otherwise healthy patient. Conclusion: This case report emphasizes the need for further research and standardized treatment guidelines. Treatment typically involves a two-stage revision with extended antifungal therapy. The optimal duration of antifungal treatment remains uncertain.
Language	English
Publishing date	2024-01-26
Publishing country	India
Document type	Case Reports
ZDB-ID	2658169-3
ISSN	2250-0685
ISSN	2250-0685
DOI	10.13107/jocr.2024.v14.i02.4256
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Article: Chaetomium globosum

Gade, Neeta / Nag, Soumyabrata / Prathipati, Kiran Kumar / Mishra, Meena / Shete, Vishal

Medical mycology case reports

2023 Volume 43, Page(s) 100618

Abstract: Atypical fungal co-infections in post-COVID-19 patients may have been underreported due to limited diagnostic methods. We present a case ... ...

Abstract	Atypical fungal co-infections in post-COVID-19 patients may have been underreported due to limited diagnostic methods. We present a case of
Language	English
Publishing date	2023-12-03
Publishing country	Netherlands
Document type	Case Reports
ZDB-ID	2670415-8
ISSN	2211-7539
ISSN	2211-7539
DOI	10.1016/j.mmcr.2023.100618
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Article ; Online: Asymptomatic filariasis and leprosy co-morbidity in a patient with suspected Guillain-Barrè syndrome: the first case report of an incidental finding in a slit-skin smear.

Nag, Soumyabrata / Gupta, Sneha / Sisodia, Juhi / Misra, Richa

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2019 Volume 1, Issue 8, Page(s) e000046

Abstract: Introduction: Lymphatic filariasis (LF) and leprosy are both endemic in India. These diseases are on the World Health Organization (WHO) list of neglected tropical diseases (NTDs), as they affect the most marginalized communities in the world, resulting ...

Abstract	Introduction: Lymphatic filariasis (LF) and leprosy are both endemic in India. These diseases are on the World Health Organization (WHO) list of neglected tropical diseases (NTDs), as they affect the most marginalized communities in the world, resulting in deformities and functional limitation. We report the first case of asymptomatic filariasis and leprosy co-morbidity in a patient with suspected Guillain-Barré syndrome. Case presentation: A 55-year-old male who was a farmer by occupation presented to the Neurology Outpatient Department (OPD) of our institute with complaints of weakness in all four limbs for the last 15 days. After admission, a detailed history revealed that the patient had been taking multi-drug therapy (MDT) for leprosy for the previous 6 months. After symptomatic management of the presenting complaints, the patient was sent to the Department of Microbiology for a consultation and six-site slit-skin sampling. The initial screening of Ziehl-Neelsen (ZN)-stained smears under a 10× objective led to the incidental finding of sheathed structures resembling microfilaria (Mf) on the smear made from ear lobules. In addition, short acid-fast bacilli (AFB) were also observed under the oil-immersion objective. Conclusion: We emphasize that a high index of suspicion and thorough screening of smears by a microbiologist is essential in specimens obtained from any body site.
Language	English
Publishing date	2019-07-26
Publishing country	England
Document type	Case Reports
ISSN	2516-8290
ISSN (online)	2516-8290
DOI	10.1099/acmi.0.000046
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Article: Investigating the Clinico-Demographic Characteristics of Dengue Fever and Its Seroprevalence at a Tertiary Care Hospital in Northern India.

Gupta, Shefali / Shakya, Akhalesh / Mishra, Namita / Islahi, Sana / Singh, Sweta / Nag, Soumyabrata / Dwivedi, Arti / Shukla, Mukesh / Sen, Somdatt / Dwivedi, Priyanka / Agarwal, Mayank / Mukherjee, Anirudh

Cureus

2024 Volume 16, Issue 4, Page(s) e57640

Abstract: Background and objective Dengue virus (DENV) is a major global health threat, causing over 50,000 deaths annually. The state of Uttar Pradesh (UP) in India faces significant challenges due to the increasing number of dengue cases detected. This study ... ...

Abstract	Background and objective Dengue virus (DENV) is a major global health threat, causing over 50,000 deaths annually. The state of Uttar Pradesh (UP) in India faces significant challenges due to the increasing number of dengue cases detected. This study aimed to assess DENV seropositivity in the Raebareli district of UP, to offer crucial insights into the region's effective control and management strategies. Materials and methods This study, after obtaining approval from the ethics committee, analyzed blood samples of individuals suspected of having dengue at a teaching hospital in rural UP between January and December 2022. To determine the disease's seroprevalence, both dengue NS1 antigen ELISA and dengue IgM Microlisa were conducted. Furthermore, RT-PCR was performed on NS1-positive samples to confirm the serotypes. The collected data were analyzed using Epi Info 7.0. Results Of the 589 suspected dengue cases, 86 (14.60%) tested positive for dengue NS1 and/or IgM. Our findings showed that males (n=330, 56.03%) and adolescents and young adults (n=301, 51.1%) from rural areas (n=523, 88.4%) were predominantly affected. Cases peaked post-monsoon, and platelet levels were notably low in NS1-positive cases. Dengue serotype 2 (DEN-2) was found in all RT-PCR-positive samples. Our results revealed a dengue seroprevalence of 14.60% (n=86), which peaked in post-monsoon months. The higher incidence among males and young adults from rural areas attending the outpatient department highlights the importance of targeted interventions and community surveillance. RT-PCR confirmed the circulation of a single serotype in the region. Conclusions This study contributes crucial insights into dengue's epidemiology and clinical profile and its findings are all the more significant now as India prepares for phase 3 trials of a quadrivalent dengue-virus vaccine in 2024. Adolescent and young adult males have an increased likelihood of acquiring the virus, and this demographic can be prioritized for vaccine trials.
Language	English
Publishing date	2024-04-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.57640
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Article ; Online: Isolation, characterization and acyclovir susceptibility of herpes simplex virus isolates among immunocompromised patients.

Nag, Soumyabrata / Sengupta, Mallika / Sarkar, Soma / Ray, Yogiraj / Chattopadhyay, Debprasad / Sengupta, Manideepa

Indian journal of sexually transmitted diseases and AIDS

2021 Volume 42, Issue 1, Page(s) 19–23

Abstract: Introduction: Herpes simplex virus (HSV) Type 2 primarily causes genital herpes, while HSV Type 1 is responsible for oral and facial lesions. The objective of this study was to isolate and characterize HSV from herpetic lesions among human ... ...

Abstract	Introduction: Herpes simplex virus (HSV) Type 2 primarily causes genital herpes, while HSV Type 1 is responsible for oral and facial lesions. The objective of this study was to isolate and characterize HSV from herpetic lesions among human immunodeficiency virus (HIV) infected patients and to evaluate their acyclovir susceptibility pattern. Materials and methods: Blister fluid and swabs from ulcers were collected from patients with clinical diagnosis of HSV infection among patients attending the HIV clinic of two tertiary care centers - Medical College, Kolkata, and School of Tropical Medicine, Kolkata. These samples were cultured in the Vero cell line. Growth of virus was noted by observing the characteristic cytopathic effect of HSV, which was further confirmed by immunofluorescence and polymerase chain reaction (PCR). These isolates were then subjected to the Vero cells with serial dilutions of acyclovir for determining the susceptibility pattern. Results: Among the 52 samples received, 8 (15.38%) showed growth of HSV. After confirmation by immunofluorescence and PCR, all seven isolates from genital samples were identified as HSV-2 and the lone isolate from oral lesion was confirmed as HSV 1. Out of the eight isolates, 25% showed resistance to acyclovir. The overall isolation rate was more from genital blister than genital ulcer which was 46.15% and 2.86%, respectively. Conclusion: HSV was isolated in 15.38% of cases of clinical herpes. There was a higher isolation rate of virus from blister fluid as compared to ulcer scrapings. Acyclovir resistance in 25% of cases is alarmingly high.
Language	English
Publishing date	2021-04-08
Publishing country	India
Document type	Journal Article
ZDB-ID	2622183-4
ISSN	2589-0565 ; 2589-0565
ISSN (online)	2589-0565
ISSN	2589-0565
DOI	10.4103/ijstd.IJSTD_60_17
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Article ; Online: Incidence of COVID-19 infection and its variation with demographic and clinical profile: lessons learned at a COVID-19 RT-PCR laboratory in Nagpur, India.

Gade, Neeta / Nag, Soumyabrata / Mishra, Meena / Akkilagunta, Sujiv / Shete, Vishal / Bidkar, Vijay / Shendre, Pooja / Patil, Divya

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2022 Volume 4, Issue 3, Page(s) 330

Abstract: Introduction. ...

Abstract	Introduction.
Language	English
Publishing date	2022-03-04
Publishing country	England
Document type	Journal Article
ISSN	2516-8290
ISSN (online)	2516-8290
DOI	10.1099/acmi.0.000330
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Article ; Online: Genetic Characterisation of Colistin Resistant

Singh, Sanjay / Pathak, Ashutosh / Rahman, Mohibur / Singh, Avinash / Nag, Soumyabrata / Sahu, Chinmoy / Prasad, Kashi Nath

Frontiers in cellular and infection microbiology

2021 Volume 11, Page(s) 666030

Abstract: Background: Increasing use of colistin has led to the world-wide emergence of mobile colistin resistant gene (: Methods: Twenty-two colistin resistant : Results: Nineteen colistin resistant : Conclusions: Colistin resistance ... ...

Abstract	Background: Increasing use of colistin has led to the world-wide emergence of mobile colistin resistant gene ( Methods: Twenty-two colistin resistant Results: Nineteen colistin resistant Conclusions: Colistin resistance in
MeSH term(s)	Anti-Bacterial Agents/pharmacology ; Bacterial Proteins/genetics ; Bacterial Proteins/pharmacology ; Colistin/pharmacology ; Drug Resistance, Bacterial/genetics ; Humans ; India ; Klebsiella Infections ; Klebsiella pneumoniae/genetics ; Microbial Sensitivity Tests ; Multilocus Sequence Typing ; Plasmids ; beta-Lactamases/genetics
Chemical Substances	Anti-Bacterial Agents ; Bacterial Proteins ; beta-Lactamases (EC 3.5.2.6) ; Colistin (Z67X93HJG1)
Language	English
Publishing date	2021-06-21
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2619676-1
ISSN	2235-2988 ; 2235-2988
ISSN (online)	2235-2988
ISSN	2235-2988
DOI	10.3389/fcimb.2021.666030
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Article ; Online: Influence of plant extracts mixed with endodontic sealers on the growth of oral pathogens in root canal: An

Saha, Sonali / Dhinsa, Gurpreet / Ghoshal, Ujjala / Afzal Hussain, Amrin Nayani Fatima / Nag, Soumyabrata / Garg, Aarti

Journal of the Indian Society of Pedodontics and Preventive Dentistry

2019 Volume 37, Issue 1, Page(s) 39–45

Abstract: Introduction: Microbes are considered as the primary etiological agents in endodontic diseases. Ways of reducing these agents are root canal debridement and antibacterial filling materials. One of the factors in determining the success of endodontic ... ...

Abstract	Introduction: Microbes are considered as the primary etiological agents in endodontic diseases. Ways of reducing these agents are root canal debridement and antibacterial filling materials. One of the factors in determining the success of endodontic treatment previously was sealing root canals with materials possessing potent bactericidal effect. Due to cytotoxic reactions of sealers and their inability to eliminate bacteria completely from dentinal tubules, trend to use natural plants extracts have been introduced. Aim: To compare antimicrobial activity of endodontic sealers added to herbal extracts. Materials and method: Three sealers mixed with three herbal extracts were evaluated against seven strains of bacteria at various time intervals using Agar Diffusion Test. The mean zones of inhibition were measured. Statistical analysis: All statistical analysis was performed using the SPSS 15 statistical software version, Chicago. Intergroup comparison was evaluated using Kruskal Walls test along with Mann Whitney U test. The Intragroup comparison was evaluatd using Friedman test along with Wilcoxon test. Results: Statistically significant zones of bacterial growth inhibition were observed largest with Zinc Oxide Eugenol based sealer when mixed with Glycyrrhiza glabra (Licorice) followed in descending order by zinc oxide eugenol based sealer mixed with Tinospora cordifolia (Guduchi) and Mimusops elengi (Bakul) respectively. Conclusion: Zinc Oxide Eugenol based sealer with herbal extracts produced largest inhibitory zones followed in descending order by Resin based sealer and Calcium hydroxide along with three herbal extracts respectively.
MeSH term(s)	Anti-Infective Agents/pharmacology ; Bacteroides fragilis/drug effects ; Dental Pulp Cavity/microbiology ; Enterococcus faecalis/drug effects ; Escherichia coli/drug effects ; Glycyrrhiza/chemistry ; In Vitro Techniques ; Microbial Sensitivity Tests ; Mimusops/chemistry ; Peptostreptococcus/drug effects ; Plant Extracts/pharmacology ; Pseudomonas aeruginosa/drug effects ; Root Canal Filling Materials/pharmacology ; Staphylococcus aureus/drug effects ; Streptococcus/drug effects ; Tinospora/chemistry ; Zinc Oxide-Eugenol Cement/pharmacology
Chemical Substances	Anti-Infective Agents ; Plant Extracts ; Root Canal Filling Materials ; Zinc Oxide-Eugenol Cement
Language	English
Publishing date	2019-01-18
Publishing country	India
Document type	Journal Article
ZDB-ID	1425154-1
ISSN	1998-3905 ; 0970-4388
ISSN (online)	1998-3905
ISSN	0970-4388
DOI	10.4103/JISPPD.JISPPD_66_18
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: First report of peritonitis caused by the vancomycin-resistant coccus

Gupta, Shefali / Sahu, Chinmoy / Nag, Soumyabrata / Saha, Uma Shankar / Prasad, Narayan / Prasad, Kashi Nath

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2019 Volume 1, Issue 5, Page(s) e000007

Abstract: Introduction: Worldwide, about one-tenth of end-stage renal disease (ESRD) patients are on peritoneal dialysis (PD). Peritonitis is a major cause of PD failure and change of therapy to haemodialysis. An update on peritoneal dialysis-related infections ... ...

Abstract	Introduction: Worldwide, about one-tenth of end-stage renal disease (ESRD) patients are on peritoneal dialysis (PD). Peritonitis is a major cause of PD failure and change of therapy to haemodialysis. An update on peritoneal dialysis-related infections has recommended the use of a first generation cephalosporin or vancomycin as an empirical therapy for Gram-positive organisms. Case presentation: An elderly female patient of ESRD on continuous ambulatory peritoneal dialysis (CAPD) was admitted with complaints of high fever and cloudy PD effluent for 2 days. She was started with vancomycin and imipenem empirically but did not improve even after 4 days. Pus cells were seen when PD fluid was examined microscopically. BACTEC culture of PD fluid isolated growth of Gram-positive cocci, which was confirmed as Conclusion: This is the first case report of
Language	English
Publishing date	2019-04-23
Publishing country	England
Document type	Case Reports
ISSN	2516-8290
ISSN (online)	2516-8290
DOI	10.1099/acmi.0.000007
Database	MEDical Literature Analysis and Retrieval System OnLINE

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