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  1. Article ; Online: Independent Confirmation.

    Herweh, Christian / Nagel, Simon

    Annals of neurology

    2022  Volume 93, Issue 2, Page(s) 424–425

    Language English
    Publishing date 2022-12-25
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80362-5
    ISSN 1531-8249 ; 0364-5134
    ISSN (online) 1531-8249
    ISSN 0364-5134
    DOI 10.1002/ana.26578
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    Zs.A 1370: Show issues Location:
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  2. Book ; Thesis: MR-tomographisches und molekulares Monitoring der Infarktentwicklung und der postischämischen Blut-Hirnschrankenstörung unter Normo- und Hypothermie in einem fokalen zerebralen Ischämiemodell der Ratte

    Nagel, Simon

    2003  

    Author's details vorgelegt von Simon Nagel
    Language German
    Size 97 Bl. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Heidelberg, Univ., Diss., 2003
    HBZ-ID HT014181604
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2004 E 1954 order for loan Magazin

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  3. Article ; Online: Response to Zhu and Wu's comment on "Endovascular therapy versus no endovascular therapy in patients receiving best medical management for acute isolated occlusion of the posterior cerebral artery: A systematic review and meta-analysis".

    Finitsis, Stephanos / Berberich, Anne / Nguyen, Thanh N / Nagel, Simon

    European journal of neurology

    2023  Volume 30, Issue 7, Page(s) 2135

    MeSH term(s) Humans ; Posterior Cerebral Artery ; Stroke/therapy ; Brain Ischemia/therapy
    Language English
    Publishing date 2023-04-05
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Letter ; Comment
    ZDB-ID 1280785-0
    ISSN 1468-1331 ; 1351-5101 ; 1471-0552
    ISSN (online) 1468-1331
    ISSN 1351-5101 ; 1471-0552
    DOI 10.1111/ene.15797
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    Zs.MO 592: Show issues

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  4. Article ; Online: Author Response: Endovascular vs Medical Management for Late Anterior Large Vessel Occlusion With Prestroke Disability: Analysis of CLEAR and RESCUE-Japan.

    Siegler, James E / Nagel, Simon / Nguyen, Thanh N

    Neurology

    2022  Volume 100, Issue 13, Page(s) 642

    MeSH term(s) Humans ; Japan ; Stroke ; Tissue Plasminogen Activator ; Endovascular Procedures ; Treatment Outcome ; Thrombectomy ; Brain Ischemia
    Chemical Substances Tissue Plasminogen Activator (EC 3.4.21.68)
    Language English
    Publishing date 2022-12-12
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000207198
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    Zs.MO 374: Show issues

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  5. Article ; Online: Importance of the Intention-to-Treat Principle.

    Nagel, Simon / Haussen, Diogo C / Nogueira, Raul G

    JAMA neurology

    2020  Volume 77, Issue 7, Page(s) 905–906

    MeSH term(s) Humans ; Intention ; Intention to Treat Analysis ; Stroke ; Thrombectomy
    Language English
    Publishing date 2020-06-21
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2702023-X
    ISSN 2168-6157 ; 2168-6149
    ISSN (online) 2168-6157
    ISSN 2168-6149
    DOI 10.1001/jamaneurol.2020.0848
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  6. Article: Editorial: Challenges in Posterior Circulation Ischemic Stroke.

    Puetz, Volker / Strbian, Daniel / Nguyen, Thanh N / Nagel, Simon

    Frontiers in neurology

    2021  Volume 12, Page(s) 789836

    Language English
    Publishing date 2021-11-17
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2021.789836
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  7. Article ; Online: What Is the Evidence for Endovascular Thrombectomy in Posterior Circulation Stroke?

    Räty, Silja / Nguyen, Thanh N / Nagel, Simon / Puetz, Volker / Alemseged, Fana / Abdalkader, Mohamad / Schonewille, Wouter J / Strbian, Daniel

    Seminars in neurology

    2023  Volume 43, Issue 3, Page(s) 345–355

    Abstract: Posterior circulation infarcts comprise approximately 25% of ischemic strokes but are less often treated with recanalization therapy and have longer treatment delays compared with anterior circulation strokes. Among posterior circulation strokes, basilar ...

    Abstract Posterior circulation infarcts comprise approximately 25% of ischemic strokes but are less often treated with recanalization therapy and have longer treatment delays compared with anterior circulation strokes. Among posterior circulation strokes, basilar artery occlusion is associated with the most severe deficits and the worst prognosis. Endovascular thrombectomy is a standard of care for patients with anterior circulation large vessel occlusion, but not until recently were the first randomized controlled trials on endovascular thrombectomy in basilar artery occlusion published. Two of the trials were neutral, whereas two others showed better functional outcome after thrombectomy up to 24 hours of symptom onset compared with best medical treatment, which in most cases had low rates of intravenous thrombolysis. According to observational data, thrombectomy seems to be safe also in isolated posterior cerebral artery occlusions and might be an option for selected patients, even if its outcome benefit is yet to be demonstrated.
    MeSH term(s) Humans ; Stroke/surgery ; Ischemic Stroke/surgery ; Thrombectomy
    Language English
    Publishing date 2023-08-18
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 603165-1
    ISSN 1098-9021 ; 0271-8235
    ISSN (online) 1098-9021
    ISSN 0271-8235
    DOI 10.1055/s-0043-1771210
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  8. Article ; Online: Letter by Purrucker et al Regarding Article, "Door-In-Door-Out Time at Primary Stroke Centers May Predict Outcome for Emergent Large Vessel Occlusion Patients".

    Purrucker, Jan C / Nagel, Simon / Gumbinger, Christoph

    Stroke

    2019  Volume 50, Issue 7, Page(s) e212

    MeSH term(s) Brain Ischemia ; Humans ; Stroke
    Language English
    Publishing date 2019-06-03
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.118.024791
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    Zs.A 448: Show issues Location:
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  9. Article ; Online: Chronic intracranial hypertension after cerebral venous and sinus thrombosis - frequency and risk factors.

    Geisbüsch, Christina / Herweh, Christian / Gumbinger, Christoph / Ringleb, Peter A / Möhlenbruch, Markus A / Nagel, Simon

    Neurological research and practice

    2021  Volume 3, Issue 1, Page(s) 28

    Abstract: Background: Cerebral venous sinus thrombosis (CVST) can infrequently lead to chronical intracranial hypertension (IH) due to the altered venous drainage. The aim of this study was to ascertain the risk of IH after CVST and to stratify underlying risk ... ...

    Abstract Background: Cerebral venous sinus thrombosis (CVST) can infrequently lead to chronical intracranial hypertension (IH) due to the altered venous drainage. The aim of this study was to ascertain the risk of IH after CVST and to stratify underlying risk factors.
    Methods: We performed a retrospective cohort analysis of all cases treated for acute CVST at our department between 2013 and 2019. IH was diagnosed at follow-up according to the modified Dandy criteria. CVST-patients with and without IH were descriptively compared conforming to available clinical and radiological data as well as outcomes.
    Results: Our study included 102 patients with acute CVST. In 70 cases complete follow-up data was available (68.6%). Seven of these patients developed symptomatic intracranial hypertension (10%; N = 7, n = 70) within a median follow-up of 6 months. Four of these patients (57.1% (N = 4, n = 7) vs. 3.2% (N = 2, n = 63); p < 0.001) presented recurrent sinus thrombosis in the further course. There were no significant differences between patients with or without IH concerning gender, age, risk factors, occluded vessels and treatment for their CVST. However the presence of visual deterioration at initial admission was higher in patients who developed IH afterwards (57.1% (N = 4, n = 7) vs. 20.6% (N = 13, n = 63); p = 0.03). Patients with chronic IH after CVST showed significantly less likely recanalization of the occluded vessel on follow-up MRI (no recanalization in 28.6% (N = 2, n = 7) vs. 4.8% (N = 3, n = 63); p = 0.02). All patients with IH had a good outcome (mRS 0-2) at discharge and follow-up.
    Conclusion: IH occurred in around 10% after CVST. Insufficient recanalization status may facilitate IH. Patients with visual disturbances seem to develop more likely IH afterwards. Patients who present IH after CVST may develop recurrent cerebral venous thrombosis.
    Language English
    Publishing date 2021-05-17
    Publishing country England
    Document type Journal Article
    ISSN 2524-3489
    ISSN (online) 2524-3489
    DOI 10.1186/s42466-021-00127-y
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  10. Article: What Is the Evidence for Endovascular Thrombectomy in Posterior Circulation Stroke?

    Räty, Silja / Nguyen, Thanh N. / Nagel, Simon / Puetz, Volker / Alemseged, Fana / Abdalkader, Mohamad / Schonewille, Wouter J. / Strbian, Daniel

    Seminars in Neurology

    (Interventional Neurology)

    2023  Volume 43, Issue 03, Page(s) 345–355

    Abstract: Posterior circulation infarcts comprise approximately 25% of ischemic strokes but are less often treated with recanalization therapy and have longer treatment delays compared with anterior circulation strokes. Among posterior circulation strokes, basilar ...

    Series title Interventional Neurology
    Abstract Posterior circulation infarcts comprise approximately 25% of ischemic strokes but are less often treated with recanalization therapy and have longer treatment delays compared with anterior circulation strokes. Among posterior circulation strokes, basilar artery occlusion is associated with the most severe deficits and the worst prognosis. Endovascular thrombectomy is a standard of care for patients with anterior circulation large vessel occlusion, but not until recently were the first randomized controlled trials on endovascular thrombectomy in basilar artery occlusion published. Two of the trials were neutral, whereas two others showed better functional outcome after thrombectomy up to 24 hours of symptom onset compared with best medical treatment, which in most cases had low rates of intravenous thrombolysis. According to observational data, thrombectomy seems to be safe also in isolated posterior cerebral artery occlusions and might be an option for selected patients, even if its outcome benefit is yet to be demonstrated.
    Keywords basilar artery occlusion ; ischemic stroke ; endovascular thrombectomy ; posterior cerebral artery occlusion ; review
    Language English
    Publishing date 2023-06-01
    Publisher Thieme Medical Publishers, Inc.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 603165-1
    ISSN 1098-9021 ; 0271-8235
    ISSN (online) 1098-9021
    ISSN 0271-8235
    DOI 10.1055/s-0043-1771210
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