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Article ; Online: Should authors of overviews of systematic reviews invite the authors of the systematic reviews they analyzed to re-evaluate or validate their methodological analysis?

Faggion, Clovis Mariano / Nagendrababu, Venkateshbabu / Dummer, Paul M H

2023 Volume 158, Page(s) 177–178

MeSH term(s)	Humans ; Systematic Reviews as Topic ; Evidence-Based Medicine ; Research Design
Language	English
Publishing date	2023-03-28
Publishing country	United States
Document type	Letter
ZDB-ID	639306-8
ISSN	1878-5921 ; 0895-4356
ISSN (online)	1878-5921
ISSN	0895-4356
DOI	10.1016/j.jclinepi.2023.03.021
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Article ; Online: Changes to the 'Author Guidelines' for animal and laboratory studies submitted to the International Endodontic Journal.

Nagendrababu, Venkateshbabu / Dummer, Paul M H

International endodontic journal

2021 Volume 54, Issue 9, Page(s) 1423–1424

MeSH term(s)	Animals ; Humans ; Laboratories ; Publishing ; Research Design
Language	English
Publishing date	2021-06-17
Publishing country	England
Document type	Editorial
ZDB-ID	603734-3
ISSN	1365-2591 ; 0143-2885
ISSN (online)	1365-2591
ISSN	0143-2885
DOI	10.1111/iej.13568
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Article ; Online: Vital pulp therapy-Factors influencing decision-making for permanent mature teeth with irreversible pulpitis: A systematic review.

Alfaisal, Yasmen / Idris, Ghassan / Peters, Ove A / Zafar, Sobia / Nagendrababu, Venkateshbabu / Peters, Christine I

International endodontic journal

2024 Volume 57, Issue 5, Page(s) 505–519

Abstract: Background: There is an increased tendency towards adopting minimally invasive interventions in dentistry, supported by advancement in materials and techniques. However, the decision-making process in choosing conservative or invasive treatments is ... ...

Abstract	Background: There is an increased tendency towards adopting minimally invasive interventions in dentistry, supported by advancement in materials and techniques. However, the decision-making process in choosing conservative or invasive treatments is influenced by several factors, particularly in permanent teeth with irreversible pulpitis. Objectives: The objective of the study was to systematically review the literature regarding factors that influence decision-making for vital pulp therapy (VPT) as definitive treatment option in permanent mature teeth diagnosed with irreversible pulpitis. Methods: Two independent reviewers searched five electronic databases (PubMed, Embase, Web of Science, Scopus and Cochrane Library). Grey literature was searched through Google Scholar and contact with experts. Defined search keys were applied, and all peer-reviewed literature published with no language nor publication date limits were included. The All studies investigating the factors influencing treatment decision-making in mature permanent teeth with irreversible pulpitis were included. The quality of included studies was assessed by two independent reviewers using the Joanna Briggs Institute quality assessment tool. Results: Six articles were included in the review. All included studies used questionnaires to characterize clinician preferences and attitudes in choosing treatment options for mature permanent teeth with irreversible pulpitis. The available evidence suggests that dentist-related factors have a significant influence on the chosen treatment in teeth with irreversible pulpitis, with speciality training and years of experience influencing the choice of VPT over other treatment options. COVID-19 reportedly swayed the dentists' decision to favour VPT. Only one article studied the influence of patient-related factors, such as age and presence of spontaneous pain on decision-making. Of note, a history of cardiovascular disease moved dentists towards prescribing VPT. Discussion: Collectively, the included studies demonstrated an overriding influence of dentist-related factors on choosing among treatment options for painful teeth diagnosed with irreversible pulpitis. Patient-related factors were acknowledged but there are also potential factors such as socio-economic constraints that were not included in the component studies. Conclusion: In teeth with irreversible pulpitis clinicians educational background influence the decision towards a specific treatment option. Further data, preferably derived from clinical records, is necessary in future investigations to explore the effect of other important factors related to both dentists and patients. Registration: PROSPERO database (CRD42022339653).
MeSH term(s)	Humans ; Pulpitis/therapy ; Dentition, Permanent ; Dental Care ; Pain ; Pulpotomy/methods
Language	English
Publishing date	2024-02-07
Publishing country	England
Document type	Systematic Review ; Journal Article ; Review
ZDB-ID	603734-3
ISSN	1365-2591 ; 0143-2885
ISSN (online)	1365-2591
ISSN	0143-2885
DOI	10.1111/iej.14036
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Article ; Online: Guided tooth autotransplantation of a palatally impacted maxillary canine into the site of a failed maxillary canine implant.

Moreno-Pérez, Jesús / Rubio Flores, David / Fernández Villares, Carlos / Nagendrababu, Venkateshbabu / Abella Sans, Francesc

Australian endodontic journal : the journal of the Australian Society of Endodontology Inc

2024

Abstract: The aim of this report is to demonstrate the guided tooth autotransplantation of a palatally impacted maxillary canine into the site of a failed maxillary canine dental implant. A 47-year-old woman visited a dental clinic complaining of loose dental ... ...

Abstract	The aim of this report is to demonstrate the guided tooth autotransplantation of a palatally impacted maxillary canine into the site of a failed maxillary canine dental implant. A 47-year-old woman visited a dental clinic complaining of loose dental implant in the left maxillary canine site, tooth #11, as well as pain and swelling of the gum around the implant. The clinical examination revealed a mobile implant along with swollen soft tissues with bleeding on probing. A periapical radiograph demonstrated peri-implant marginal bone loss. Cone beam computed tomography sections revealed that tooth #11 was impacted palatally. The implant was removed and replaced with the impacted canine via guided autotransplantation and posterior orthodontic alignment. The patient was recalled at 1, 3, 6, 9, 12, 24 and 48 months after the procedure. During this period, the patient was symptom-free and radiographic examination at 2 years revealed no periapical pathosis or root resorption.
Language	English
Publishing date	2024-03-21
Publishing country	Australia
Document type	Case Reports
ZDB-ID	2146484-4
ISSN	1747-4477 ; 1329-1947
ISSN (online)	1747-4477
ISSN	1329-1947
DOI	10.1111/aej.12840
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Article ; Online: Restoration of Teeth with Severely Compromised Tooth Structure using Digital Planning Combined with Orthodontic Magnetic Extrusion-A Report of 2 Cases.

Casaponsa, Jaume / Vinothkumar, Thilla Sekar / Dummer, Paul M H / Nagendrababu, Venkateshbabu / Abella Sans, Francesc

Journal of endodontics

2024 Volume 50, Issue 6, Page(s) 852–858

Abstract: This report outlines 2 digitally planned cases in which the teeth underwent magnetic extrusion to preserve the supracrestal tissue attachment and regain the ferrule, followed by their restoration. Case 1: A 42-year-old man with the chief concern of a ... ...

Abstract	This report outlines 2 digitally planned cases in which the teeth underwent magnetic extrusion to preserve the supracrestal tissue attachment and regain the ferrule, followed by their restoration. Case 1: A 42-year-old man with the chief concern of a fractured right maxillary second premolar. Following the completion of root canal treatment, the remaining tooth structure was insufficient to create a ferrule for tooth restoration. For this scenario, a rapid magnetic extrusion technique was performed on tooth #4 to obtain an approximate 3-mm ferrule. The condition of both the dentition and the restorative margin was acceptable 18 months following treatment. Case 2: A 62-year-old man with the chief complaint of mobility on both sides of the maxillary arch in relation to a tooth-supported fixed partial denture (FPD). Following removal of the FPD, multiple extractions were carried out and tooth #6 was subjected to magnetic extrusion in 3 stages to a maximum of 4 mm to obtain a ferrule. At the 18-month and 3-year follow-up appointments, the tooth had no symptoms and the gingiva around the restorations had optimal architecture and margins. The 3-dimensional digital planning was helpful in precisely positioning the magnets within the tooth and the provisional restorations to facilitate axial extrusion. The extruded teeth were restored with zirconia crowns in both cases. The beneficial outcomes observed from these cases provides evidence that the integration of digital planning and magnetic extrusion holds promise as a method for reconstructing teeth with crowns that are significantly compromised.
MeSH term(s)	Humans ; Male ; Middle Aged ; Adult ; Orthodontic Extrusion/methods ; Bicuspid/diagnostic imaging ; Dental Restoration, Permanent/methods ; Magnetics ; Tooth Fractures/diagnostic imaging ; Tooth Fractures/therapy ; Root Canal Therapy/methods ; Computer-Aided Design ; Denture, Partial, Fixed
Language	English
Publishing date	2024-02-29
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	752412-2
ISSN	1878-3554 ; 0099-2399
ISSN (online)	1878-3554
ISSN	0099-2399
DOI	10.1016/j.joen.2024.02.017
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Article ; Online: Endodontic Applications of Propolis in Primary and Permanent Teeth: A Scoping Review of Clinical Studies.

Alghutaimel, Hayat / Matoug-Elwerfelli, Manal / Nagendrababu, Venkateshbabu / Howell Dummer, Paul Michael

European endodontic journal

2024

Abstract: Objective: The use of propolis-based materials within endodontics to promote pulp wound healing or disinfect the root canal system has been a recent focus of scientists and clinicians. This is mainly because of the well-documented antimicrobial, anti- ... ...

Abstract	Objective: The use of propolis-based materials within endodontics to promote pulp wound healing or disinfect the root canal system has been a recent focus of scientists and clinicians. This is mainly because of the well-documented antimicrobial, anti-inflammatory, immunomodulatory and wound healing properties of propolis. This scoping review critically appraises the literature on the clinical applications of propolis-based compounds during endodontic therapy of primary and permanent teeth. Methods: An electronic literature search was performed in Scopus, PubMed, and Web of Science up to and including October 2023 to identify studies assessing the use of propolis during endodontic therapy of primary and permanent teeth. A combination of relevant MeSh terms and keywords was used. Only human clinical studies written in English were included. The identified manuscripts were screened and assessed for inclusion by two independent authors. Eligible manuscripts were then subjected to critical appraisal and data extraction with the information being summarised according to their clinical application. Results: A total of 26 human clinical studies were identified and included in the analysis. Propolis was investigated for use in the primary and permanent dentitions as a direct pulp capping or pulpotomy material as well as in root canal disinfection and root filling of teeth with non-vital pulps. Overall, the studies reported that the use of propolis was associated with promising outcomes in terms of efficacy to control inflammation, enhance tissue repair, and disinfection of the root canal system. However, a critical appraisal of the studies revealed a range of methodological and reporting deficiencies, resulting in unreliable results and conclusions in terms of the clinical outcomes reported. Conclusion: Although the studies on the use of propolis-based materials in endodontics reported promising clinical outcomes, they had a range of methodological and reporting flaws. Further well-designed and properly reported controlled clinical studies are essential to derive sound evidence-based conclusions on propolis-based materials. Furthermore, guidelines for quality assurance and safe use of propolis-based materials are necessary to enhance their production for commercial use in endodontics.
Language	English
Publishing date	2024-05-17
Publishing country	Turkey
Document type	Journal Article
ISSN	2548-0839
ISSN (online)	2548-0839
DOI	10.14744/eej.2024.65487
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Article ; Online: Propolis Use in Dentistry: A Narrative Review of Its Preventive and Therapeutic Applications.

Alghutaimel, Hayat / Matoug-Elwerfelli, Manal / Alhaji, Mayada / Albawardi, Fatimah / Nagendrababu, Venkateshbabu / Dummer, Paul Michael Howell

International dental journal

2024 Volume 74, Issue 3, Page(s) 365–386

Abstract: Propolis is a resinous substance produced naturally by bees, and it consists of the exudates of plants mixed with enzymes, wax, and pollen. Propolis continues to gain considerable scientific interest due to its potential health benefits. The modern-day ... ...

Abstract	Propolis is a resinous substance produced naturally by bees, and it consists of the exudates of plants mixed with enzymes, wax, and pollen. Propolis continues to gain considerable scientific interest due to its potential health benefits. The modern-day use of propolis in pharmaceutical preparations, such as toothpastes, mouthwashes, chewable tablets, mucoadhesive gels, and sprays, is increasing. However, the effectiveness of using propolis-containing pharmaceuticals in dentistry is not clear. The present paper aims to review the literature on the dental applications of propolis in preventive dentistry, periodontics, oral medicine, and restorative dentistry and discuss its clinical effectiveness. A literature search was conducted using Scopus, PubMed, and Web of Science databases. In total, 104 studies were included, of which 46 were laboratory studies, 5 animal studies, and 53 human clinical studies. Overall, the laboratory studies revealed a range of antimicrobial effects of propolis on oral pathogens. Clinical investigations of propolis in biofilm and dental caries control as well as adjuvant periodontal therapies reported positive outcomes in terms of plaque control, pathogenic microbial count reduction, and periodontal tissue inflammation control. Additional investigations included the use of propolis for the management of recurrent aphthous stomatitis, oral mucositis, and cavity disinfection after caries removal as well as the development of a range of restorative dental materials. Based on the reported outcomes of the studies, the clinical usage of propolis has potential. However, the majority of the evidence is derived from studies with flaws in their methodological design, making their results and conclusions questionable. As a consequence, properly designed and well-reported clinical studies are required to affirm the effectiveness of propolis for dental applications. Additionally, the safety of propolis and the optimal concentrations and extraction methods for its clinical use warrant further investigation. Utilisation of standardised propolis extracts will help in quality control of propolis-based products and lead to the achievement of reproducible outcomes in research studies.
MeSH term(s)	Propolis/therapeutic use ; Humans ; Dental Caries/prevention & control ; Anti-Infective Agents/therapeutic use ; Animals ; Preventive Dentistry ; Biofilms/drug effects ; Stomatitis, Aphthous/drug therapy ; Stomatitis, Aphthous/prevention & control
Language	English
Publishing date	2024-02-19
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	218262-2
ISSN	1875-595X ; 0020-6539
ISSN (online)	1875-595X
ISSN	0020-6539
DOI	10.1016/j.identj.2024.01.018
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Article ; Online: Reporting guidelines enhance the quality and impact of research in Dental Traumatology.

Nagendrababu, Venkateshbabu / Duncan, Henry F / Abbott, Paul V / Dummer, Paul M H

Dental traumatology : official publication of International Association for Dental Traumatology

2023 Volume 39, Issue 3, Page(s) 285–290

Abstract: Reporting guidelines assist basic scientists, translational healthcare researchers and clinicians to publish manuscripts of the highest standard by improving the accuracy, transparency and completeness of the publications they submit to journals. This ... ...

Abstract	Reporting guidelines assist basic scientists, translational healthcare researchers and clinicians to publish manuscripts of the highest standard by improving the accuracy, transparency and completeness of the publications they submit to journals. This paper provides an overview of reporting guidelines relevant for the specialty of dental traumatology and discusses their application, significance and potential impact. The Preferred Reporting Items for study Designs in Endodontology (PRIDE) suite of reporting guidelines includes a range of study designs that can be used within the broad field of Endodontics but they are also applicable to dental traumatology and other dental disciplines (Preferred Reporting Items for Case reports in Endodontics [PRICE] 2020, Preferred Reporting Items for RAndomized Trials in Endodontics [PRIRATE] 2020; Preferred Reporting Items for Animal Studies in Endodontology [PRIASE] 2021; Preferred Reporting Items for Laboratory studies in Endodontology [PRILE] 2021 and Preferred Reporting items for OBservational studies in Endodontics [PROBE] 2023). The PRIDE guidelines were developed by an extensive network of globally renowned academics, researchers and expert clinicians working within dentistry using an accepted and validated consensus methodology. The aim of the PRIDE guidelines is to improve the overall quality of manuscripts describing case reports, randomized trials, animal research, laboratory studies and observational studies. Although attention to reporting guidelines adds a degree of complexity when writing reports, such guidelines provide a template for authors to develop standardized manuscripts of the highest quality, which will allow colleagues, readers and the wider public to have confidence that their findings are valid and robust. They also provide evidence to editors that manuscripts submitted to journals comply with the highest global standards of reporting within their respective discipline. Endorsement of the PRIDE guidelines by editors will lead to improvements in the reporting quality of manuscripts submitted to their journals.
MeSH term(s)	Animals ; Traumatology ; Research Report ; Endodontics ; Research Design ; Consensus
Language	English
Publishing date	2023-02-10
Publishing country	Denmark
Document type	Journal Article
ZDB-ID	2030722-6
ISSN	1600-9657 ; 1600-4469
ISSN (online)	1600-9657
ISSN	1600-4469
DOI	10.1111/edt.12824
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Article ; Online: Effectiveness of continuous chelation irrigation protocol in endodontics: a scoping review of laboratory studies.

La Rosa, Giusy Rita Maria / Plotino, Gianluca / Nagendrababu, Venkateshbabu / Pedullà, Eugenio

Odontology

2023 Volume 112, Issue 1, Page(s) 1–18

Abstract: This scoping review aimed to synthesize and explore the current boundaries and limitations of laboratory research on the effectiveness of continuous chelation irrigation protocol in endodontics. This scoping review was reported according to the Preferred ...

Abstract	This scoping review aimed to synthesize and explore the current boundaries and limitations of laboratory research on the effectiveness of continuous chelation irrigation protocol in endodontics. This scoping review was reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Extension for Scoping Reviews. Literature search was conducted on Pubmed and Scopus to identify all laboratory studies evaluating smear layer and hard-tissue debris removal or, antimicrobial efficacy, or dentine erosion induced by continuous chelation. Two independent reviewers performed the all review steps and the relevant items were recorded. Seventy-seven potentially relevant studies were identified. Finally, 23 laboratory studies met the eligibility criteria for qualitative synthesis. Seven studies focused on the smear layer/debris removal outcome, 10 on antimicrobial activity, and 10 on dentine erosion. In general, the continuous chelation protocol was equally or more effective in the cleanliness of root canals and antimicrobial activity compared with traditional sequential protocol. In addition, etidronate solutions seemed to be milder chelating agents compared to those with EDTA, thus resulting in reduced or no dentine erosion and roughness modification. Yet, the methodological differences among the included studies limit the results' generalizability. The continuous chelation seems to be equally or more effective in all investigated outcomes when compared with the traditional sequential protocol. The methodological variability among the studies and shortcomings in the methods employed limit the generalizability and clinical relevance of the results. Standardized laboratory conditions combined with reliable three-dimensional investigation approaches are necessary to obtain clinically informative findings.
MeSH term(s)	Humans ; Smear Layer ; Chelating Agents/pharmacology ; Anti-Infective Agents/pharmacology ; Dental Care ; Systematic Reviews as Topic
Chemical Substances	Chelating Agents ; Anti-Infective Agents
Language	English
Publishing date	2023-07-11
Publishing country	Japan
Document type	Journal Article ; Review
ZDB-ID	2092085-4
ISSN	1618-1255 ; 1618-1247
ISSN (online)	1618-1255
ISSN	1618-1247
DOI	10.1007/s10266-023-00835-8
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Article ; Online: Assessment of biomechanical behavior of immature non-vital incisors with various treatment modalities by means of three-dimensional quasi-static finite element analysis.

Hassouneh, Layla / Matoug-Elwerfelli, Manal / Al-Omari, Taher / Setzer, Frank C / Nagendrababu, Venkateshbabu

Scientific reports

2023 Volume 13, Issue 1, Page(s) 17491

Abstract: The objectives of this study were to evaluate the stress distribution and risk of fracture of a non-vital immature maxillary central incisor subjected to various clinical procedures using finite element analysis (FEA). A three-dimensional model of an ... ...

Abstract	The objectives of this study were to evaluate the stress distribution and risk of fracture of a non-vital immature maxillary central incisor subjected to various clinical procedures using finite element analysis (FEA). A three-dimensional model of an immature central incisor was developed, from which six main models were designed: untreated immature tooth (C), standard apical plug (AP), resin composite (RC), glass-fibre post (GFP), regeneration procedure (RET), and regeneration with induced root maturation (RRM). Mineral trioxide aggregate (MTA) or Biodentine
MeSH term(s)	Incisor ; Finite Element Analysis ; Silicates ; Calcium Compounds
Chemical Substances	tricalcium silicate (404G39282C) ; Silicates ; Calcium Compounds
Language	English
Publishing date	2023-10-15
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-44609-2
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