Article ; Online: Exploring the potential of Mustard (Brassica spp.) seeds through 'Kolhu' traditional method of extraction and novel identification of an anti-cancer dipeptide, Aurantiamide acetate (Asperglaucide) on ultra-performance liquid chromatography-mass spectrometry coupled with quadrupole time-of-flight (UPLC/MS-QToF) analytical platform.
2024 Volume 446, Page(s) 138870
Abstract: Mustard (Brassica spp.) is one of the world's oldest condiments in the food basket, which holds a significant place in the global culinary landscape due to historical prominence and perceived health benefits. This study explores the extraction of oils ... ...
| Abstract | Mustard (Brassica spp.) is one of the world's oldest condiments in the food basket, which holds a significant place in the global culinary landscape due to historical prominence and perceived health benefits. This study explores the extraction of oils from Mustard seeds by employing traditional 'Kolhu' method, modern supercritical fluid, and solvent extraction techniques. This study, for the first-time, identified Aurantiamide acetate, a potent anti-cancer dipeptide in Mustard seeds using ultra-performance liquid chromatography-mass spectrometry coupled with quadrupole time-of-flight (UPLC/MS-QToF) analytical platform. The analytical methodology was meticulously validated encompassing optimal parameters such as limit of detection, limit of quantification, precision, accuracy, linearity and robustness, within the range. Interestingly, 'Kolhu' method of oil extraction exhibited better yield of Aurantiamide acetate, suggesting superior efficiency of traditional methods. This study accentuates the importance of classical extraction methods, used traditionally, and emphasizes that naturally occurring substances indeed could be harnessed for better health. |
|---|---|
| MeSH term(s) | Chromatography, High Pressure Liquid/methods ; Tandem Mass Spectrometry/methods ; Mustard Plant ; Liquid Chromatography-Mass Spectrometry ; Dipeptides ; Seeds |
| Chemical Substances | N-benzoylphenylalanylphenylalinol acetate (56121-42-7) ; Dipeptides |
| Language | English |
| Publishing date | 2024-02-28 |
| Publishing country | England |
| Document type | Journal Article |
| ZDB-ID | 243123-3 |
| ISSN | 1873-7072 ; 0308-8146 |
| ISSN (online) | 1873-7072 |
| ISSN | 0308-8146 |
| DOI | 10.1016/j.foodchem.2024.138870 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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