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  1. Book ; Online ; E-Book: A forest environment tax scheme in Japan

    Nakayama, Keiko

    toward water source cultivation

    2022  

    Author's details Keiko Nakayama
    Keywords Forest conservation
    Subject code 910.5
    Language English
    Size 1 online resource (132 pages)
    Publisher Springer
    Publishing place Singapore
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 981-16-9352-8 ; 981-16-9351-X ; 978-981-16-9351-9 ; 978-981-16-9352-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Coming of Age in Science: Just Look?

    Nakayama, Ken

    Annual review of vision science

    2021  Volume 7, Page(s) 1–17

    Abstract: With Professor Patrick Cavanagh, I started the Harvard Vision Sciences Laboratory in 1990. Blessed with the largesse of a wealthy university, we occupied a very large common space. Here, students pursued their own projects in a uniquely cooperative and ... ...

    Abstract With Professor Patrick Cavanagh, I started the Harvard Vision Sciences Laboratory in 1990. Blessed with the largesse of a wealthy university, we occupied a very large common space. Here, students pursued their own projects in a uniquely cooperative and exciting scientific environment. The times were just right in the emerging and expanding field of vision science. With good thesis projects under their belt, most of the students went on to successful careers. However, my own coming of age in science did not have such a promising start. It only started well into my thirties when I joined the Smith Kettlewell Eye Research Institute in San Francisco. Providentially, it was there that I had the rare and unique opportunity to work closely and essentially only with peers (not students). Through these intense collaborations, I found my way as a scientist. Most of this account describes these formative years.
    Language English
    Publishing date 2021-06-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2805730-2
    ISSN 2374-4650 ; 2374-4642
    ISSN (online) 2374-4650
    ISSN 2374-4642
    DOI 10.1146/annurev-vision-100419-120946
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: [The Influence of Echo Train Duration on Heavily T

    Ariya, Wataru / Nakayama, Kansuke

    Nihon Hoshasen Gijutsu Gakkai zasshi

    2023  Volume 79, Issue 7, Page(s) 708–716

    Abstract: Magnetic resonance cholangiopancreatography (MRCP) is a valuable non-invasive technique that depicts bile or pancreatic juice as hyperintense in heavily ... ...

    Abstract Magnetic resonance cholangiopancreatography (MRCP) is a valuable non-invasive technique that depicts bile or pancreatic juice as hyperintense in heavily T
    MeSH term(s) Cholangiopancreatography, Magnetic Resonance/methods ; Phantoms, Imaging ; Magnetic Resonance Imaging/methods
    Language Japanese
    Publishing date 2023-06-09
    Publishing country Japan
    Document type English Abstract ; Journal Article
    ZDB-ID 2269092-X
    ISSN 1881-4883 ; 0369-4305
    ISSN (online) 1881-4883
    ISSN 0369-4305
    DOI 10.6009/jjrt.2023-1369
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Signatures of adaptation in myopia-related genes on the sunlight exposure hypothesis.

    Xia, Tian / Nakayama, Kazuhiro

    Journal of physiological anthropology

    2023  Volume 42, Issue 1, Page(s) 25

    Abstract: Background: Myopia is a common eye disorder that results from gene-environment interactions. The prevalence of myopia varies across populations, and exposure to bright sunlight may prevent its development. We hypothesize that local adaptation to light ... ...

    Abstract Background: Myopia is a common eye disorder that results from gene-environment interactions. The prevalence of myopia varies across populations, and exposure to bright sunlight may prevent its development. We hypothesize that local adaptation to light environments during human migration played a role in shaping the genetic basis of myopia, and we aim to investigate how the environment influences the genetic basis of myopia.
    Method: We utilized the whole-genome variant data of the 1000 Genomes Project for analysis. We searched myopia-associated loci that were under selection in Europeans using population branch statistics and the number of segregating sites by length statistics. The outliers of these statistics were enriched in the Kyoto Encyclopedia of Genes and Genomes pathways and the gene ontology biological process terms in searching for pathways that were under selection. We applied Bayesian inference to estimate the correlation between environmental factors and allele frequencies of the selected loci and performed causal inference of myopia using two-sample Mendelian randomization analysis.
    Results: We detected signatures of adaptation in vision and light perception pathways, supporting our hypothesis of sunlight adaptation. We discovered a strong correlation between latitude and allele frequencies in genes that are under significant selection, and we found pleiotropic effects of pigmentation or circadian rhythm genes on myopia, indicating that sunlight exposure influences the genetic diversity of myopia.
    Conclusions: Myopia genes involved in light perception showed signs of selection. Local adaptation during human migration shaped the genetic basis of myopia and may have influenced its global prevalence distribution.
    MeSH term(s) Humans ; Bayes Theorem ; Circadian Rhythm ; Gene Frequency ; Myopia/genetics ; Sunlight ; Mendelian Randomization Analysis
    Language English
    Publishing date 2023-11-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2248072-9
    ISSN 1880-6805 ; 1880-6791 ; 1345-3475
    ISSN (online) 1880-6805
    ISSN 1880-6791 ; 1345-3475
    DOI 10.1186/s40101-023-00341-4
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2899: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Arene C-H Amination with

    Nakayama, Kaii / Okada, Yohei

    The Journal of organic chemistry

    2023  Volume 88, Issue 9, Page(s) 5913–5922

    Abstract: Arene C-H aminations using catalytic amounts of a 2,3-dichloro-5,6-dicyano- ...

    Abstract Arene C-H aminations using catalytic amounts of a 2,3-dichloro-5,6-dicyano-
    Language English
    Publishing date 2023-04-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.3c00293
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4473: Show issues Location:
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  6. Article ; Online: Characteristics of throwing arm movement for an elongated implement: a comparison of the javelin and baseball throwing.

    Makino, Mizuki / Nakayama, Koichi / Ando, Yuka / Tauchi, Kenji

    The Journal of sports medicine and physical fitness

    2024  

    Abstract: Background: In javelin, although many previous studies have examined throwing movements that can increase initial velocity, the characteristics of throwing arm movement an elongated implement have not been clarified. The purpose of the present study was ...

    Abstract Background: In javelin, although many previous studies have examined throwing movements that can increase initial velocity, the characteristics of throwing arm movement an elongated implement have not been clarified. The purpose of the present study was to examine the characteristics of the throwing movement of an elongated implement by comparing throwing movement between a javelin and baseball.
    Methods: Twelve male javelin throwers were asked to perform a javelin throw (JT) and a baseball long toss (LT) twice. The three-dimensional coordinates of reflective markers attached to the athlete's body, javelin, and baseball were measured using an optical motion capture system. %Trajectory was used as an index to evaluate the degree to which the hand was moved linearly during the throw. A smaller value of this indicator meant that the hand was move closer to a straight line. The joint angles in the throwing arm were obtained by calculating the Euler angles between body segments. These data were used to compare JT and LT.
    Results: %Trajectory showed that JT was significantly smaller than LT. Significant differences in the joint angles of the throwing arm were noted between JT and LT.
    Conclusions: JT showed a kinematic pattern in which the hand was moved more linearly than in baseball long toss.
    Language English
    Publishing date 2024-02-06
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 410823-1
    ISSN 1827-1928 ; 0022-4707
    ISSN (online) 1827-1928
    ISSN 0022-4707
    DOI 10.23736/S0022-4707.24.15706-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 326: Show issues Location:
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  7. Article ; Online: Artifactual atomic displacements on surfaces using annular dark-field images with image simulation.

    Kobayashi, Shunsuke / Ooe, Kousuke / Nakayama, Kei / Kuwabara, Akihide

    Microscopy (Oxford, England)

    2024  

    Abstract: We investigated artifactual atomic displacements on a Pt (111) surface using annular dark-field (ADF) scanning transmission electron microscopy (STEM) images under ideal conditions with multi-slice image simulation. Pt atomic columns on the surface ... ...

    Abstract We investigated artifactual atomic displacements on a Pt (111) surface using annular dark-field (ADF) scanning transmission electron microscopy (STEM) images under ideal conditions with multi-slice image simulation. Pt atomic columns on the surface exhibited artifact displacement. The bright spots shifted slightly toward the interior of the crystal, indicating that ADF imaging underestimates atomic distance measurements on the crystal surface. Multiple peak fitting is an effective method for determining the positions of bright spots and obtaining more accurate atomic positions while reducing the impact of surface-related artifacts. This is important for the measurement of interatomic distances on crystal surfaces, particularly for catalyst particles.
    Language English
    Publishing date 2024-01-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2707496-1
    ISSN 2050-5701 ; 2050-5698
    ISSN (online) 2050-5701
    ISSN 2050-5698
    DOI 10.1093/jmicro/dfae001
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    Zs.B 1211: Show issues Location:
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  8. Article ; Online: A randomized controlled trial on the effects of decision aids for choosing discharge destinations of older stroke patients.

    Aoki, Yoriko / Nakayama, Kazuhiro / Yonekura, Yuki

    PloS one

    2024  Volume 19, Issue 1, Page(s) e0272115

    Abstract: Background: In Japanese medical practice, older stroke survivors are overwhelmed with information regarding their discharge locations, creating more decision-making challenges. A randomized controlled trial evaluated the influence of decision aids (DAs) ...

    Abstract Background: In Japanese medical practice, older stroke survivors are overwhelmed with information regarding their discharge locations, creating more decision-making challenges. A randomized controlled trial evaluated the influence of decision aids (DAs) for matching older stroke patients and their families' values concerning decisional conflict and participation in discharge destination decisions.
    Methods: Participants were randomly allocated to intervention and control groups. The intervention spanned two months, from admission to discharge, at which times participants were surveyed. DAs were provided to the intervention group, and brochures to the control group. The primary endpoint was decisional conflict, assessed using the Decisional Conflict Scale (DCS). The secondary endpoint decision-making participation was assessed using the Control Preference Scale (CPS) decision-making roles and a 10-point Visual Analog Scale for participation rate. An independent t-test analyzed decisional conflict scores and participation rates to examine between-group differences. The chi-square independence test evaluated roles in decision-making scores. Post hoc subgroup analyses were performed.
    Results: Ninety-nine participants (intervention group n = 51; control group n = 48) were included in the full analysis set, with a dropout rate of 38.4%. No significant group differences were found in decision-making conflict [t (99) = 0.69, p = 0.49, d = 0.14] and roles in decision-making scores [χ2 (5) = 3.65, p = 0.46]. However, a significant group difference was found in the participation rate [t (99) = 2.24, p = 0.03, d = 0.45]. DA tended to reduce uncertainty and promote participation rates, especially in participants living alone and unable to decide their discharge destination.
    Conclusions: The use of DA with older stroke patients did not significantly decrease decisional conflicts. In addition, the participation rate in decision-making increased, but their active role did not. Further studies should be conducted to understand the methods of offering DA, their ideal durations, and identify their beneficiaries.
    MeSH term(s) Humans ; Cerebral Infarction ; Decision Making ; Decision Support Techniques ; Patient Discharge ; Patient Participation ; Uncertainty ; Aged
    Language English
    Publishing date 2024-01-25
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0272115
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  9. Article ; Online: Current concept of low-grade serous ovarian carcinoma.

    Nakayama, Kentaro / Razia, Sultana / Ishibashi, Tomoka / Kyo, Satoru

    Translational cancer research

    2024  Volume 13, Issue 1, Page(s) 6–10

    Language English
    Publishing date 2024-01-25
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2901601-0
    ISSN 2219-6803 ; 2218-676X
    ISSN (online) 2219-6803
    ISSN 2218-676X
    DOI 10.21037/tcr-23-1161
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Nucleus accumbens degeneration in spinocerebellar ataxia type 2: a preliminary study.

    Nakayama, Kenjiro / Nemoto, Kiyotaka / Arai, Tetsuaki

    Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society

    2024  Volume 24, Issue 2, Page(s) 345–354

    Abstract: Background: Spinocerebellar ataxia type 2 (SCA2) exhibits mainly cerebellar and oculomotor dysfunctions but also, frequently, cognitive impairment and neuropsychological symptoms. The mechanism of the progression of SCA2 remains unclear. This study ... ...

    Abstract Background: Spinocerebellar ataxia type 2 (SCA2) exhibits mainly cerebellar and oculomotor dysfunctions but also, frequently, cognitive impairment and neuropsychological symptoms. The mechanism of the progression of SCA2 remains unclear. This study aimed to evaluate longitudinal structural changes in the brains of SCA2 patients based on atrophy rate.
    Methods: The OpenNeuro Dataset ds001378 was used. It comprises the demographic data and two magnetic resonance images each of nine SCA2 patients and 16 healthy controls. All structural images were preprocessed using FreeSurfer software, and each region's bilateral volume was summed. Atrophy rates were calculated based on the concept of symmetrised percent change and compared between SCA2 patients and healthy controls using non-parametric statistics. As post hoc analysis, correlation analysis was performed between infratentorial volume ratio and the accumbens area atrophy rates in SCA2 patients.
    Results: There were no significant differences between groups for age, gender, and the time between scans. Statistical analysis indicated a significantly larger atrophy rate of the accumbens area in SCA2 patients than in controls. Additionally, the infratentorial volume ratio and accumbens area atrophy rates showed moderate negative correlation.
    Conclusions: This study found that nucleus accumbens (NAc) atrophy was significantly accelerated in SCA2 patients. Anatomically, the NAc is densely connected with infratentorial brain regions, so it is reasonable to posit that degeneration propagates from the cerebellum and brainstem to the NAc and other supratentorial areas. Functionally, the NAc is essential for appropriate behaviour, so NAc degeneration might contribute to neuropsychological symptoms in SCA2 patients.
    MeSH term(s) Humans ; Atrophy ; Brain ; Cognitive Dysfunction ; Nucleus Accumbens/pathology ; Spinocerebellar Ataxias/pathology
    Language English
    Publishing date 2024-01-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2213105-X
    ISSN 1479-8301 ; 1346-3500
    ISSN (online) 1479-8301
    ISSN 1346-3500
    DOI 10.1111/psyg.13080
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6210: Show issues Location:
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