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  1. AU="Nakeshbandi, Mohamed"
  2. AU=Sonthalia Nikhil AU=Sonthalia Nikhil
  3. AU="Kohanbash, Gary" AU="Kohanbash, Gary"
  4. AU=Nawrocki Mariusz J.
  5. AU="Jayme Borensztajn"
  6. AU=Schaerf Raymond H M
  7. AU="Chachar, Aijaz Zeeshan Khan"
  8. AU=Forster H V
  9. AU=Yang G-F
  10. AU="Kaplan, Robert C"
  11. AU="Rood, Julian I."
  12. AU="Manhes, Caroline"
  13. AU="Jacobsen, Cristiane Cavalcanti"
  14. AU="Anja Kukic"
  15. AU="Zhang, N"
  16. AU="Cunningham, Thomas J"
  17. AU="Wu, Y P"
  18. AU="Sumbul, Sabiha"
  19. AU="Razolli, Daniela S"
  20. AU="Asif, Mohsin"
  21. AU="Choudhary, Diksha"
  22. AU="Liu, Yongmei"
  23. AU=Goldshaid Liat
  24. AU="Sandeep Dhayade"
  25. AU="Ashkin, David"
  26. AU="Yukioka, Hideo"
  27. AU="Giles, M"
  28. AU="Keshavarzian, Tina"
  29. AU="Richard Holtmeier"
  30. AU=Sanborn Keri B
  31. AU=Crestani Larissa AU=Crestani Larissa
  32. AU=Nassiri Amir Ahmad
  33. AU="Keiser, Olivia"
  34. AU="Scholz, Martin"
  35. AU="Vassilis Pigadas" AU="Vassilis Pigadas"
  36. AU="Schlievert, Patrick M"
  37. AU=Egan Katie G
  38. AU="Benzadón, Mariano"
  39. AU="Truong, Thérèse"
  40. AU="de Oliveira, Aline Lima"
  41. AU="Lehto, Sonya G"
  42. AU="Simi Jacob"
  43. AU="Shipman, Michael"
  44. AU=Pons Linda
  45. AU="Notoya, A"
  46. AU="Williams, Olajide A"
  47. AU=Errington Jeff
  48. AU="Tortolani, Christina C"
  49. AU="Patel, Jenil R"
  50. AU="Aires, Rafaela"
  51. AU="Habibelahi, Abbas"
  52. AU="Temes, Javier"
  53. AU="Miwa, Toru"
  54. AU="Jaller, Elvira"
  55. AU="Manso Sanchez, L M"

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  1. Artikel ; Online: Adherence to Procalcitonin Measurement in Inpatient Care: a Guide for Antibiotic Stewardship and High Value Care.

    Dronamraju, Veena / Moffat, Gordon T / Nakeshbandi, Mohamed

    Journal of general internal medicine

    2019  Band 35, Heft 2, Seite(n) 609–610

    Mesh-Begriff(e) Anti-Bacterial Agents/therapeutic use ; Antimicrobial Stewardship ; Biomarkers ; Diagnostic Tests, Routine ; Humans ; Inpatients ; Procalcitonin ; Respiratory Tract Infections/drug therapy
    Chemische Substanzen Anti-Bacterial Agents ; Biomarkers ; Procalcitonin
    Sprache Englisch
    Erscheinungsdatum 2019-07-24
    Erscheinungsland United States
    Dokumenttyp Letter
    ZDB-ID 639008-0
    ISSN 1525-1497 ; 0884-8734
    ISSN (online) 1525-1497
    ISSN 0884-8734
    DOI 10.1007/s11606-019-05197-y
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Association between Influenza Vaccination and severe COVID-19 outcomes at a designated COVID-only hospital in Brooklyn.

    Umasabor-Bubu, Ogie Q / Bubu, Omonigho M / Mbah, Alfred K / Nakeshbandi, Mohamed / Taylor, Tonya N

    American journal of infection control

    2021  Band 49, Heft 10, Seite(n) 1327–1330

    Abstract: Maintaining influenza vaccination at high coverage has the potential to prevent a proportion of COVID-19 morbidity and mortality. We examined whether flu-vaccination is associated with severe corona virus disease 2019 (COVID-19) disease, as measured by ... ...

    Abstract Maintaining influenza vaccination at high coverage has the potential to prevent a proportion of COVID-19 morbidity and mortality. We examined whether flu-vaccination is associated with severe corona virus disease 2019 (COVID-19) disease, as measured by intensive care unit (ICU)-admission, ventilator-use, and mortality. Other outcome measures included hospital length of stay and total ICU days. Our findings showed that flu-vaccination was associated with a significantly reduced likelihood of an ICU admission especially among aged <65 and non-obese patients. Public health promotion of flu-vaccination may help mitigate the overwhelming demand for critical COVID-19 care pending the large-scale availability of COVID-19 vaccines.
    Mesh-Begriff(e) COVID-19 ; COVID-19 Vaccines ; Hospital Mortality ; Hospitals ; Humans ; Influenza, Human/prevention & control ; Intensive Care Units ; SARS-CoV-2 ; Vaccination
    Chemische Substanzen COVID-19 Vaccines
    Sprache Englisch
    Erscheinungsdatum 2021-04-20
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 392362-9
    ISSN 1527-3296 ; 0196-6553
    ISSN (online) 1527-3296
    ISSN 0196-6553
    DOI 10.1016/j.ajic.2021.04.006
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: COVID-19 related deaths in an urban academic medical center in Brooklyn - a descriptive case series.

    McCracken, James Andrew / Nakeshbandi, Mohamed / Arace, Jeffrey / Riley, Wayne J / Sharma, Roopali

    Translational medicine communications

    2020  Band 5, Heft 1, Seite(n) 12

    Abstract: Background: Available studies are lacking in analysis of baseline demographics and hospital presentation of patients at risk of expiring due to coronavirus disease 2019 (COVID-19), particularly Black American patients. We conducted a retrospective chart ...

    Abstract Background: Available studies are lacking in analysis of baseline demographics and hospital presentation of patients at risk of expiring due to coronavirus disease 2019 (COVID-19), particularly Black American patients. We conducted a retrospective chart review to determine similarities in demographics and hospital presentation among patients who expired due to COVID-19 at an academic medical center in Brooklyn, New York.
    Study design and methods: This is a retrospective observational study of 200 patients who expired due to complications of COVID-19. Patients were included in this study if they had laboratory-confirmed SARS-CoV-2 infection and expired during their admission. Data were collected on patients who expired between March 17 and April 16, 2020.
    Results: A vast majority of patients were Black Americans (89%) with no history of international travel who had more than one comorbidity (81%), with the most common comorbidities being hypertension (84·5%), diabetes mellitus (57·5%), and obesity (41·5%). Fifty-five percent of our patient population had three or more comorbidities. Among patients with available data, C-reactive protein, lactate dehydrogenase, and ferritin values were elevated above normal limits at admission. Dyspnea was the most common presenting symptom (92·5%). Most (90·5%) presented within the first week of symptoms, with a median time of symptoms prior to expiration being 8·42 days (IQR 5·57-12·72).
    Interpretation: Socioeconomic status and healthcare inequalities have greatly affected the Black population of Brooklyn, New York, and these disparities become even more apparent in COVID-19 infection. Patients presenting with numerous comorbidities and elevated inflammatory markers represent a population at high risk of in-hospital mortality.
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-08-13
    Erscheinungsland England
    Dokumenttyp Journal Article
    ISSN 2396-832X
    ISSN (online) 2396-832X
    DOI 10.1186/s41231-020-00065-y
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: Diagnosing Common Deadly Infections in the Era of COVID-19: A Case Report.

    Zyablitskaya, Mariya / Suarez, Maria J / Gupta, Aanchal / Samaroo-Campbell, Jevon / Nakeshbandi, Mohamed / Chapnick, Edward K / Ghitan, Monica

    Infectious diseases in clinical practice (Baltimore, Md.)

    2021  Band 29, Heft 6, Seite(n) e462–e464

    Abstract: The COVID-19 pandemic has challenged clinicians to recognize COVID-19 as one of the diagnostic explanation for common presentations, including fever, cough, and shortness of breath. Latent tuberculosis is responsible for 80% of active tuberculosis cases ... ...

    Abstract The COVID-19 pandemic has challenged clinicians to recognize COVID-19 as one of the diagnostic explanation for common presentations, including fever, cough, and shortness of breath. Latent tuberculosis is responsible for 80% of active tuberculosis cases in the United States, and presentation can vary from asymptomatic to disseminated disease. This potential diagnosis should be thoroughly investigated in foreign-born patients in US hospitals, regardless of travel history and presenting symptoms. We report a patient diagnosed with postpartum disseminated tuberculosis with hematogenous spread to the fetus.
    Sprache Englisch
    Erscheinungsdatum 2021-05-25
    Erscheinungsland United States
    Dokumenttyp Case Reports
    ZDB-ID 1162378-0
    ISSN 1056-9103
    ISSN 1056-9103
    DOI 10.1097/IPC.0000000000001042
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: COVID-19 related deaths in an urban academic medical center in Brooklyn – a descriptive case series

    McCracken, James Andrew / Nakeshbandi, Mohamed / Arace, Jeffrey / Riley, Wayne J. / Sharma, Roopali

    Translational Medicine Communications

    2020  Band 5, Heft 1

    Schlagwörter covid19
    Sprache Englisch
    Verlag Springer Science and Business Media LLC
    Erscheinungsland us
    Dokumenttyp Artikel ; Online
    ISSN 2396-832X
    DOI 10.1186/s41231-020-00065-y
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Artikel: COVID-19 related deaths in an urban academic medical center in Brooklyn – a descriptive case series

    McCracken, James Andrew / Nakeshbandi, Mohamed / Arace, Jeffrey / Riley, Wayne J. / Sharma, Roopali

    Translational Medicine Communications

    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #713824
    Datenquelle COVID19

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  7. Artikel: Impact of Sepsis Intervention Protocol (SIP) on Adherence to Three-hour and Six-hour Bundles and Mortality Outcomes in the Emergency Department

    Igiebor, Osagie / Nakeshbandi, Mohamed / Mehta, Ninfa / Ozaki, Randi / Lucchesi, Michael / Daley, Maryanne / Salifu, Moro O / McFarlane, Samy I

    Abstract: Sepsis is a commonly encountered diagnosis affecting nearly 1.7 million adults in the USA annually. According to Center for Disease Control (CDC), over 270,000 Americans die of sepsis each year and 1 in 3 hospital mortalities is attributed to sepsis. The ...

    Abstract Sepsis is a commonly encountered diagnosis affecting nearly 1.7 million adults in the USA annually. According to Center for Disease Control (CDC), over 270,000 Americans die of sepsis each year and 1 in 3 hospital mortalities is attributed to sepsis. The Surviving Sepsis Campaign (SSC) Guidelines for management of severe sepsis and septic shock published in 2004 provide key elements in the treatment of sepsis that are organized into two bundles of care, the "resuscitation" and "management" bundles, including interventions to be accomplished within specified timeframes. In this quality improvement study, we implemented a sepsis intervention protocol (SIP) intended to increase adherence to 3-hour and 6-hour bundles, and to examine the impact on mortality of patients presenting with severe sepsis and septic shock in our emergency department. We analyzed data from our emergency department as reported to the New York State Department of Health (NYSDOH) from 2017Q2 to 2018Q2 (April 2017 -June 2018), the period prior to implementation of SIP, compared to data from 2018Q3 to 2019Q2 (July 2018 to June 2019) after implementation of SIP. The implementation of SIP resulted in increased3-hour and 6-hour bundle adherence and showed a clinically significant reduction of the mean pre-intervention hospital percent mortality of 40.3% to a mean post-intervention hospital percent mortality of 28.7%. A t-test analysis of the pre and post intervention mean hospital percent mortality revealed a reduction in mortality outcomes that was also statistically significant (p <0.05). Our study demonstrates that a well-designed and implemented SIP can increase bundle adherence and is highly effective in reducing mortality among high-risk population.
    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #730074
    Datenquelle COVID19

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  8. Artikel ; Online: The impact of obesity on COVID-19 complications: a retrospective cohort study.

    Nakeshbandi, Mohamed / Maini, Rohan / Daniel, Pia / Rosengarten, Sabrina / Parmar, Priyanka / Wilson, Clara / Kim, Julie Minjae / Oommen, Alvin / Mecklenburg, Max / Salvani, Jerome / Joseph, Michael A / Breitman, Igal

    International journal of obesity (2005)

    2020  Band 44, Heft 9, Seite(n) 1832–1837

    Abstract: Background: Obesity is an epidemic in New York City, the global epicenter of the coronavirus pandemic. Previous studies suggest that obesity is a possible risk factor for adverse outcomes in COVID-19.: Objective: To elucidate the association between ... ...

    Abstract Background: Obesity is an epidemic in New York City, the global epicenter of the coronavirus pandemic. Previous studies suggest that obesity is a possible risk factor for adverse outcomes in COVID-19.
    Objective: To elucidate the association between obesity and COVID-19 outcomes.
    Design: Retrospective cohort study of COVID-19 hospitalized patients tested between March 10 and April 13, 2020.
    Setting: SUNY Downstate Health Sciences University, a COVID-only hospital in New York.
    Participants: In total, 684 patients were tested for COVID-19 and 504 were analyzed. Patients were categorized into three groups by BMI: normal (BMI 18.50-24.99), overweight (BMI 25.00-29.99), and obese (BMI ≥ 30.00).
    Measurements: Primary outcome was 30-day in-hospital mortality, and secondary outcomes were intubation, acute kidney injury (AKI), acute respiratory distress syndrome (ARDS), and acute cardiac injury (ACI).
    Results: There were 139 patients (27%) with normal BMI, 150 patients who were overweight (30%), and 215 patients with obesity (43%). After controlling for age, gender, diabetes, hypertension, and qSOFA score, there was a significantly increased risk of mortality in the overweight (RR 1.4, 95% CI 1.1-1.9) and obese groups (RR 1.3, 95% CI 1.0-1.7) compared with those with normal BMI. Similarly, there was a significantly increased relative risk for intubation in the overweight (RR 2.0, 95% CI 1.2-3.3) and obese groups (RR 2.4, 95% CI 1.5-4.0) compared with those with normal BMI. Obesity did not affect rates of AKI, ACI, or ARDS. Furthermore, obesity appears to significantly increase the risk of mortality in males (RR 1.4, 95% CI 1.0-2.0, P = 0.03), but not in females (RR 1.2, 95% CI 0.77-1.9, P = 0.40).
    Conclusion: This study reveals that patients with overweight and obesity who have COVID-19 are at increased risk for mortality and intubation compared to those with normal BMI. These findings support the hypothesis that obesity is a risk factor for COVID-19 complications and should be a consideration in management of COVID-19.
    Mesh-Begriff(e) Acute Kidney Injury/epidemiology ; Adult ; Aged ; Betacoronavirus ; Body Mass Index ; COVID-19 ; Comorbidity ; Coronavirus Infections/complications ; Coronavirus Infections/epidemiology ; Coronavirus Infections/mortality ; Diabetes Mellitus, Type 2/epidemiology ; Female ; Humans ; Hypertension/epidemiology ; Intubation, Intratracheal/statistics & numerical data ; Male ; Middle Aged ; New York City/epidemiology ; Obesity/epidemiology ; Overweight/epidemiology ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/mortality ; Retrospective Studies ; Risk Factors ; SARS-CoV-2
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-07-25
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 752409-2
    ISSN 1476-5497 ; 0307-0565
    ISSN (online) 1476-5497
    ISSN 0307-0565
    DOI 10.1038/s41366-020-0648-x
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1325: Hefte anzeigen Standort:
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  9. Artikel: The impact of obesity on COVID-19 complications: a retrospective cohort study

    Nakeshbandi, Mohamed / Maini, Rohan / Daniel, Pia / Rosengarten, Sabrina / Parmar, Priyanka / Wilson, Clara / Kim, Julie Minjae / Oommen, Alvin / Mecklenburg, Max / Salvani, Jerome / Joseph, Michael A / Breitman, Igal

    Int J Obes (Lond)

    Abstract: BACKGROUND: Obesity is an epidemic in New York City, the global epicenter of the coronavirus pandemic. Previous studies suggest that obesity is a possible risk factor for adverse outcomes in COVID-19. OBJECTIVE: To elucidate the association between ... ...

    Abstract BACKGROUND: Obesity is an epidemic in New York City, the global epicenter of the coronavirus pandemic. Previous studies suggest that obesity is a possible risk factor for adverse outcomes in COVID-19. OBJECTIVE: To elucidate the association between obesity and COVID-19 outcomes. DESIGN: Retrospective cohort study of COVID-19 hospitalized patients tested between March 10 and April 13, 2020. SETTING: SUNY Downstate Health Sciences University, a COVID-only hospital in New York. PARTICIPANTS: In total, 684 patients were tested for COVID-19 and 504 were analyzed. Patients were categorized into three groups by BMI: normal (BMI 18.50-24.99), overweight (BMI 25.00-29.99), and obese (BMI ≥ 30.00). MEASUREMENTS: Primary outcome was 30-day in-hospital mortality, and secondary outcomes were intubation, acute kidney injury (AKI), acute respiratory distress syndrome (ARDS), and acute cardiac injury (ACI). RESULTS: There were 139 patients (27%) with normal BMI, 150 patients who were overweight (30%), and 215 patients with obesity (43%). After controlling for age, gender, diabetes, hypertension, and qSOFA score, there was a significantly increased risk of mortality in the overweight (RR 1.4, 95% CI 1.1-1.9) and obese groups (RR 1.3, 95% CI 1.0-1.7) compared with those with normal BMI. Similarly, there was a significantly increased relative risk for intubation in the overweight (RR 2.0, 95% CI 1.2-3.3) and obese groups (RR 2.4, 95% CI 1.5-4.0) compared with those with normal BMI. Obesity did not affect rates of AKI, ACI, or ARDS. Furthermore, obesity appears to significantly increase the risk of mortality in males (RR 1.4, 95% CI 1.0-2.0, P = 0.03), but not in females (RR 1.2, 95% CI 0.77-1.9, P = 0.40). CONCLUSION: This study reveals that patients with overweight and obesity who have COVID-19 are at increased risk for mortality and intubation compared to those with normal BMI. These findings support the hypothesis that obesity is a risk factor for COVID-19 complications and should be a consideration in management of COVID-19.
    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #680193
    Datenquelle COVID19

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  10. Artikel ; Online: The impact of obesity on COVID-19 complications

    Nakeshbandi, Mohamed / Maini, Rohan / Daniel, Pia / Rosengarten, Sabrina / Parmar, Priyanka / Wilson, Clara / Kim, Julie Minjae / Oommen, Alvin / Mecklenburg, Max / Salvani, Jerome / Joseph, Michael A. / Breitman, Igal

    International Journal of Obesity

    a retrospective cohort study

    2020  Band 44, Heft 9, Seite(n) 1832–1837

    Schlagwörter Nutrition and Dietetics ; Medicine (miscellaneous) ; Endocrinology, Diabetes and Metabolism ; covid19
    Sprache Englisch
    Verlag Springer Science and Business Media LLC
    Erscheinungsland us
    Dokumenttyp Artikel ; Online
    ZDB-ID 752409-2
    ISSN 1476-5497 ; 0307-0565
    ISSN (online) 1476-5497
    ISSN 0307-0565
    DOI 10.1038/s41366-020-0648-x
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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