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  1. AU="Nakonezny, Paul A"
  2. AU="Sun, Yuan-Yuan"
  3. AU="Palazuelos Molinero, Jorge"
  4. AU="Papamikos, Vassilios"
  5. AU="Toledano-Osorio, Manuel"
  6. AU="Aston, Kenneth"
  7. AU="Crowe, Remle"
  8. AU="El-Yazbi, Amira F"
  9. AU=Wong Kai Yau AU=Wong Kai Yau
  10. AU="Wais, Verena"
  11. AU=Barbieri Lavinia AU=Barbieri Lavinia
  12. AU=McKay Jennifer S
  13. AU="Frohn, Marina"
  14. AU="Blaksley, C"
  15. AU="Heri Hermasyah"
  16. AU="Charlier, Filip"
  17. AU="Mihalopoulos, N"
  18. AU="Fernandez, S Gomez"

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  1. Artikel ; Online: The relationship between patient-reported outcomes and preoperative pain characteristics in patients who underwent total hip arthroplasty.

    Everett, Brandon Paul / Sherrill, Garrett / Nakonezny, Paul A / Wells, Joel E

    Bone & joint open

    2022  Band 3, Heft 4, Seite(n) 332–339

    Abstract: Aims: This study aims to answer the following questions in patients with hip osteoarthritis (OA) who underwent total hip arthroplasty (THA): are patient-reported outcome measures (PROMs) affected by the location of the maximum severity of pain?; are ... ...

    Abstract Aims: This study aims to answer the following questions in patients with hip osteoarthritis (OA) who underwent total hip arthroplasty (THA): are patient-reported outcome measures (PROMs) affected by the location of the maximum severity of pain?; are PROMs affected by the presence of non-groin pain?; are PROMs affected by the severity of pain?; and are PROMs affected by the number of pain locations?
    Methods: We reviewed 336 hips (305 patients) treated with THA for hip OA from December 2016 to November 2019 using pain location/severity questionnaires, modified Harris Hip Score (mHHS), Hip Outcome Score (HOS), international Hip Outcome Tool (iHOT-12) score, and radiological analysis. Descriptive statistics, analysis of covariance (ANCOVA), and Spearman partial correlation coefficients were used.
    Results: There was a significant difference in iHOT-12 scores between groups experiencing the most severe pain in the groin and the trochanter (p = 0.039). Additionally, more favourable mHHS scores were related to the presence of preoperative pain in trochanter (p = 0.049), lower back (p = 0.056), lateral thigh (p = 0.034), and posterior thigh (p = 0.005). Finally, the maximum severity of preoperative pain and number of pain locations had no significant relationship with PROMs (maximum severity: HHS: p = 0.928, HOS: p = 0.163, iHOT-12 p = 0.233; number of pain locations: HHS: p = 0.211; HOS: p = 0.801; iHOT-12: p = 0.112).
    Conclusion: Although there was a significant difference in iHOT-12 scores between patients with the most severe pain in the groin or trochanter, and the presence of pain in the trochanter, lower back, lateral thigh, or posterior thigh was related to higher mHHS scores, the majority of preoperative pain characteristics did not have a significant impact on outcomes. Therefore, a broad array of patients with hip OA might expect similar, favourable outcomes from THA notwithstanding preoperative pain characteristics. Cite this article:
    Sprache Englisch
    Erscheinungsdatum 2022-04-20
    Erscheinungsland England
    Dokumenttyp Journal Article
    ISSN 2633-1462
    ISSN (online) 2633-1462
    DOI 10.1302/2633-1462.34.BJO-2021-0206.R1
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Hip Preservation Surgery in Patients With Femoroacetabular Impingement Syndrome and Acetabular Dysplasia Improves Functional Measures and Pain Catastrophizing.

    Gaddis, John M / de Souza, Rafael / Montanez, Benjamin / Nakonezny, Paul A / Laboret, Bretton / Bialaszewski, Ryan / Wells, Joel E

    Cureus

    2024  Band 16, Heft 1, Seite(n) e52461

    Abstract: Background Chronic hip pain is a debilitating condition that severely reduces one's quality of life. Prior studies uncovered a link between hip pathologies and pain catastrophizing, anxiety, and depression. The purpose of this study was to investigate ... ...

    Abstract Background Chronic hip pain is a debilitating condition that severely reduces one's quality of life. Prior studies uncovered a link between hip pathologies and pain catastrophizing, anxiety, and depression. The purpose of this study was to investigate whether hip preservation surgery in patients with femoroacetabular impingement syndrome (FAIS) and acetabular dysplasia (AD) improves functional outcomes and pain catastrophizing. Methods Patients with FAIS and AD were requested to complete a hip questionnaire both preoperatively and postoperatively at a single academic center (University of Texas Southwestern Medical Center, Dallas, Texas, USA). Pain catastrophizing was evaluated using the pain catastrophizing scale, and pain level was assessed using the visual analog scale. Assessments of hip functional outcomes included the hip outcome score (HOS) and the hip disability and osteoarthritis outcome score (HOOS). Outcome measures before and after treatment were compared using the dependent samples t-test. A correlation analysis, using the Spearman partial correlation coefficient (rs), was conducted to evaluate the relationship between variables. Results The results indicated a clinically significant improvement in functional measures and pain catastrophizing in patients who underwent hip preservation surgery. The most significant discovery was an inverse relationship between both HOOS quality of life (rs=-0.293, p=0.0065, false discovery rate (FDR)=0.0210) and HOS activities of daily living (rs=-0.242, p=0.0254, FDR=0.0423) and pain catastrophizing; however, similar improvements were seen in pain catastrophizing with improvements in other functional outcomes. Conclusion Undergoing hip preservation surgery for patients with AD or FAIS improved their hip functional measures and decreased pain catastrophizing postoperatively. The improvement of hip function, quality of life, and pain catastrophizing reveals an intricate link between the functional outcomes of hip preservation surgery and pain catastrophizing.
    Sprache Englisch
    Erscheinungsdatum 2024-01-17
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.52461
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: A retrospective, naturalistic study of deep brain stimulation and vagal nerve stimulation in young patients.

    Yuruk, Deniz / Ozger, Can / Garzon, Juan F / Nakonezny, Paul A / Vande Voort, Jennifer L / Croarkin, Paul E

    Brain and behavior

    2024  Band 14, Heft 3, Seite(n) e3452

    Abstract: Introduction: Invasive neuromodulation interventions such as deep brain stimulation (DBS) and vagal nerve stimulation (VNS) are important treatments for movement disorders and epilepsy, but literature focused on young patients treated with DBS and VNS ... ...

    Abstract Introduction: Invasive neuromodulation interventions such as deep brain stimulation (DBS) and vagal nerve stimulation (VNS) are important treatments for movement disorders and epilepsy, but literature focused on young patients treated with DBS and VNS is limited. This retrospective study aimed to examine naturalistic outcomes of VNS and DBS treatment of epilepsy and dystonia in children, adolescents, and young adults.
    Methods: We retrospectively assessed patient demographic and outcome data that were obtained from electronic health records. Two researchers used the Clinical Global Impression scale to retrospectively rate the severity of neurologic and psychiatric symptoms before and after patients underwent surgery to implant DBS electrodes or a VNS device. Descriptive and inferential statistics were used to examine clinical effects.
    Results: Data from 73 patients were evaluated. Neurologic symptoms improved for patients treated with DBS and VNS (p < .001). Patients treated with DBS did not have a change in psychiatric symptoms, whereas psychiatric symptoms worsened for patients treated with VNS (p = .008). The frequency of postoperative complications did not differ between VNS and DBS groups.
    Conclusion: Young patients may have distinct vulnerabilities for increased psychiatric symptoms during treatment with invasive neuromodulation. Child and adolescent psychiatrists should consider a more proactive approach and greater engagement with DBS and VNS teams that treat younger patients.
    Mesh-Begriff(e) Child ; Adolescent ; Young Adult ; Humans ; Retrospective Studies ; Deep Brain Stimulation/adverse effects ; Vagus Nerve Stimulation/adverse effects ; Epilepsy/etiology ; Dystonia/etiology ; Treatment Outcome ; Drug Resistant Epilepsy/therapy
    Sprache Englisch
    Erscheinungsdatum 2024-03-11
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2623587-0
    ISSN 2162-3279 ; 2162-3279
    ISSN (online) 2162-3279
    ISSN 2162-3279
    DOI 10.1002/brb3.3452
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: The effect of parent-adolescent discrepancies in reports of familial dysfunction and depression on suicidal ideation in adolescents.

    Sachs, Raney / Nakonezny, Paul A / Balzen, Kennedy M / Heerschap, Jessica / Kennard, Betsy D / Emslie, Graham J / Stewart, Sunita M

    Suicide & life-threatening behavior

    2024  

    Abstract: Introduction: Parents and adolescents are often discrepant in their reports of adolescent psychosocial factors. Few studies have addressed parent-adolescent discrepancies in subjective ratings of familial dysfunction and depression as longitudinal ... ...

    Abstract Introduction: Parents and adolescents are often discrepant in their reports of adolescent psychosocial factors. Few studies have addressed parent-adolescent discrepancies in subjective ratings of familial dysfunction and depression as longitudinal predictor variables, and none have done so in a treatment setting for adolescents with acute suicidality. This study examined how parent-adolescent discrepancies in familial dysfunction and depression impact adolescent treatment response in an intensive outpatient program for suicidality.
    Methods: Adolescents (N = 315) were assessed at treatment entry and exit for familial dysfunction, depression, and suicidal ideation. Parents received parallel assessments of familial dysfunction and adolescent depression at each time point. A polynomial regression was conducted to determine whether parent-adolescent discrepancies in reports of familial dysfunction and depression at entry related to the treatment outcome of adolescent-reported depression and suicide ideation at exit.
    Results: Significant discrepancies were present with on average adolescents reporting more depression and familial dysfunction than parents. Entry discrepancy in familial dysfunction (but not depression) predicted suicide ideation at exit.
    Conclusions: Our results suggest that parent-adolescent discrepancies in perception of familial dysfunction is a risk factor for poor outcomes in suicidal youth and might be a fruitful target in treatment programs.
    Sprache Englisch
    Erscheinungsdatum 2024-02-22
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 750058-0
    ISSN 1943-278X ; 0047-4592 ; 0363-0234
    ISSN (online) 1943-278X
    ISSN 0047-4592 ; 0363-0234
    DOI 10.1111/sltb.13062
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: The Relationship Between Pelvic Tilt and Clinical Outcomes After Hip Preservation Surgery in Femoroacetabular Impingement Syndrome and Hip Dysplasia.

    Thummala, Abhinav / Nakonezny, Paul A / Mulligan, Edward P / Chhabra, Avneesh / Wells, Joel

    Orthopedics

    2023  Band 46, Heft 6, Seite(n) e341–e346

    Abstract: Pelvic tilt is thought to be a compensatory mechanism in hip pathology, specifically in patients with femoroacetabular impingement syndrome (FAIS) and hip dysplasia. This study investigated the relationship between preoperative pelvic tilt and ... ...

    Abstract Pelvic tilt is thought to be a compensatory mechanism in hip pathology, specifically in patients with femoroacetabular impingement syndrome (FAIS) and hip dysplasia. This study investigated the relationship between preoperative pelvic tilt and postoperative outcomes in patients undergoing hip preservation surgery for FAIS or hip dysplasia. We reviewed a prospective hip preservation database for demographic, radiographic, and outcome data for 89 patients who underwent hip preservation surgery with a primary diagnosis of FAIS or dysplasia from 2016 to 2020. Pelvic tilt was assessed on the standing anteroposterior radiograph with the pubic symphysis to sacroiliac joint (PS-SI) distance measurement. The International Hip Outcome Tool 12 (iHOT-12), Hip Outcome Score, Harris Hip Score, UCLA activity score, and European Quality of Life-Visual Analog Scale were used to assess hip function and pain preoperatively and postoperatively. The mean pelvic tilt (PS-SI distance) was 86.4±18.3 mm for the FAIS group and 96.2±15.1 mm for the dysplasia group. The statistical analysis demonstrated a positive relationship between pelvic tilt and change in iHOT-12 score (
    Mesh-Begriff(e) Humans ; Femoracetabular Impingement/diagnostic imaging ; Femoracetabular Impingement/surgery ; Hip Dislocation/diagnostic imaging ; Hip Dislocation/surgery ; Hip Joint/surgery ; Quality of Life ; Treatment Outcome ; Hip Dislocation, Congenital ; Arthroscopy/methods ; Retrospective Studies ; Activities of Daily Living
    Sprache Englisch
    Erscheinungsdatum 2023-04-12
    Erscheinungsland United States
    Dokumenttyp Review ; Journal Article
    ZDB-ID 424447-3
    ISSN 1938-2367 ; 0147-7447
    ISSN (online) 1938-2367
    ISSN 0147-7447
    DOI 10.3928/01477447-20230407-04
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Predictors of Failure to Rescue After Postoperative Respiratory Failure: A Retrospective Cohort Analysis of 13,047 Patients Using the ACS-NSQIP Dataset.

    Karamchandani, Kunal / Khorsand, Sarah / Ebeling, Callie / Yan, Luying / Nakonezny, Paul A / Carr, Zyad J

    The Journal of surgical research

    2023  Band 293, Seite(n) 482–489

    Abstract: Introduction: Death after suffering a postoperative complication (failure to rescue) is an area of concern, and its occurrence after postoperative respiratory failure (PRF) is not well defined. We seek to identify the predictors of failure to rescue in ... ...

    Abstract Introduction: Death after suffering a postoperative complication (failure to rescue) is an area of concern, and its occurrence after postoperative respiratory failure (PRF) is not well defined. We seek to identify the predictors of failure to rescue in patients who develop PRF.
    Methods: A retrospective cohort study of adults undergoing noncardiac surgery who developed PRF (postoperative unplanned intubation and receipt of mechanical ventilation for longer than 48 h) was conducted using the American College of Surgeons National Surgical Quality Improvement Project database. Predictors of failure to rescue after PRF were identified using the Least Absolute Shrinkage and Selection Operator (LASSO)-penalized variable selection method, with the Bayesian information criterion, in the context of a multiple logistic regression model (with Firth's bias correction).
    Results: Of the 13,047 patients that formed our final evaluable study cohort, 3669 (28.1%) patients died within 30 days of surgery. We identified age, sex, American Society of Anesthesiologists physical status, presence of preoperative ascites, disseminated cancer, bleeding disorders, elevated preoperative creatinine, and low preoperative prealbumin levels as predictors of failure to rescue. The area under the curve for the final model was 0.6804, with a standard error of 0.0104 (95% CI area under the curve: 0.6600 to 0.7008).
    Conclusions: We observed that almost 30% of patients that develop respiratory failure after noncardiac surgery die within 30 days of surgery. The validated eight-variable perioperative predictive model provides a risk estimate for death after PRF and may be useful for the purposes of preoperative planning, prognostication, decision making and resource allocation in patients who develop this complication.
    Mesh-Begriff(e) Adult ; Humans ; Retrospective Studies ; Bayes Theorem ; Cohort Studies ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Respiratory Insufficiency/etiology ; Respiratory Insufficiency/therapy ; Risk Factors ; Risk Assessment/methods
    Sprache Englisch
    Erscheinungsdatum 2023-10-10
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 80170-7
    ISSN 1095-8673 ; 0022-4804
    ISSN (online) 1095-8673
    ISSN 0022-4804
    DOI 10.1016/j.jss.2023.09.030
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: The Effect of Length of Hospital Stay and Patient Factors on Patient Satisfaction in an Academic Hospital.

    Diwan, Waqaar / Nakonezny, Paul A / Wells, Joel

    Orthopedics

    2020  Band 43, Heft 6, Seite(n) 373–379

    Abstract: The Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) is a metric for patient satisfaction consisting of 19 questions divided into 10 domains. Scores affect hospital reimbursements and accreditation and may play a role in patient ... ...

    Abstract The Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) is a metric for patient satisfaction consisting of 19 questions divided into 10 domains. Scores affect hospital reimbursements and accreditation and may play a role in patient outcomes. It is unclear how length of stay and other factors affect each of the 10 domains. This retrospective review gathered data of 600 patients between December 2008 and January 2017 who completed the HCAHPS survey. The odds of complete satisfaction in each of the 10 domains was evaluated. The results suggest increased length of stay is associated with lower odds of patient satisfaction and decreased likelihood of recommending the hospital. The odds of being completely satisfied regarding communication with physicians, discharge information, and responsiveness of the hospital staff, as well as the odds of recommending the hospital to others, were lower if the care provider was younger than the patient. Obese patients were also more likely to be satisfied with responsiveness and care transition. Male patients were more satisfied with communication about medications (odds ratio [OR], 1.694), care transition (OR, 1.489), and cleanliness (OR, 2.120). Medicare and fewer consults were related to increased odds of patient satisfaction with care transition (OR, 1.748 and 0.573, respectively). Males, older patients, and White patients were more likely to recommend the hospital (OR, 1.476, 1.025, and 1.690, respectively). Length of stay affects patient satisfaction and likelihood of recommending the hospital to others. Other factors such as a younger provider age than the patient, lower body mass index, female sex, non-Medicare insurance, and higher number of consults are also associated with lower satisfaction in various domains. Hospital systems can bolster patient satisfaction by strategizing day-of-surgery and weekend staffing to reduce length of stay. [Orthopedics. 2020;43(6):373-379.].
    Mesh-Begriff(e) Age Factors ; Aged ; Female ; Hospitals/standards ; Humans ; Length of Stay ; Male ; Medicare ; Middle Aged ; Orthopedic Procedures ; Patient Satisfaction ; Physician-Patient Relations ; Retrospective Studies ; United States
    Sprache Englisch
    Erscheinungsdatum 2020-09-22
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 424447-3
    ISSN 1938-2367 ; 0147-7447
    ISSN (online) 1938-2367
    ISSN 0147-7447
    DOI 10.3928/01477447-20200910-02
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel: The relationship between pre-operative pain characteristics and periacetabular osteotomy outcomes in patients with acetabular dysplasia.

    Everett, Brandon P / Nakonezny, Paul A / Mulligan, Edward P / Chhabra, Avneesh / Wells, Joel

    Journal of hip preservation surgery

    2022  Band 9, Heft 1, Seite(n) 44–50

    Abstract: The aims of this study were to determine if pre-operative pain characteristics (location of maximum severity of pain, presence of non-groin pain, maximum severity of pain and number of pain locations) affect patient-reported outcome measures in patients ... ...

    Abstract The aims of this study were to determine if pre-operative pain characteristics (location of maximum severity of pain, presence of non-groin pain, maximum severity of pain and number of pain locations) affect patient-reported outcome measures in patients undergoing periacetabular osteotomy (PAO) for acetabular dysplasia. We reviewed 52 hips (48 patients) treated with PAO for acetabular dysplasia from February 2017 to July 2020 using modified Harris Hip Score (mHHS), Hip Outcome Score (HOS) and international Hip Outcome Tool (iHOT-12) score, radiographic analysis and pain location/severity questionnaires. Descriptive statistics, analysis of covariance and Spearman partial correlation coefficients were implemented. Twenty-six hips experienced the most severe pre-operative pain in the groin, and 26 hips experienced equal or greater pain in a non-groin location. Outcome scores between these groups were not significantly different (mHHS
    Sprache Englisch
    Erscheinungsdatum 2022-01-21
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2773022-0
    ISSN 2054-8397
    ISSN 2054-8397
    DOI 10.1093/jhps/hnac004
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Dysplastic hips demonstrate increased joint translation at higher body mass index.

    Zhang, Angela W / Nakonezny, Paul A / Chhabra, Avneesh / Fey, Nicholas / Wells, Joel

    Skeletal radiology

    2022  Band 52, Heft 4, Seite(n) 715–723

    Abstract: Objective: To determine which radiographic measures used to define the severity of hip dysplasia are associated with hip joint translation and to investigate relationships between position, body mass index, and joint translation.: Materials and ... ...

    Abstract Objective: To determine which radiographic measures used to define the severity of hip dysplasia are associated with hip joint translation and to investigate relationships between position, body mass index, and joint translation.
    Materials and methods: This is a cross-sectional retrospective study evaluating 10 validated radiographic measures of dysplasia on weight-bearing AP pelvis and supine 45-degree bilateral Dunn radiographs of 93 young adults with symptomatic hip dysplasia presenting to a single academic institution between October 2016 and May 2019. We determined the difference between standing and supine measurements for each hip and the correlation of each measure with the patient's body mass index.
    Results: Femoral head extrusion index was 2.49% lower on supine X-ray (p = 0.0020). Patients with higher body mass index had higher center gap distance (p = 0.0274), femoral head extrusion (p = 0.0170), and femoral head lateralization (p = 0.0028) when standing. They also had higher Tönnis angle (p
    Conclusion: Translation of the hip joint with position change is demonstrated by decreased femoral head extrusion index on supine X-ray. Patients with higher body mass index had more dysplastic hips, as measured by five of six radiographic outcomes of dysplasia, and experienced more translation with weight-bearing, reflected by increased femoral head lateralization.
    Mesh-Begriff(e) Young Adult ; Humans ; Hip Dislocation/diagnostic imaging ; Retrospective Studies ; Cross-Sectional Studies ; Body Mass Index ; Osteotomy ; Hip Joint/diagnostic imaging ; Acetabulum
    Sprache Englisch
    Erscheinungsdatum 2022-10-13
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 527592-1
    ISSN 1432-2161 ; 0364-2348
    ISSN (online) 1432-2161
    ISSN 0364-2348
    DOI 10.1007/s00256-022-04205-3
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Predicting Remission From Depression in Youth Receiving Outpatient Medication Management.

    Balzen, Kennedy M / Hensley, Jane K / Nakonezny, Paul A / Jones, Jessica / Kennard, Betsy D / Emslie, Graham J

    The Journal of clinical psychiatry

    2023  Band 84, Heft 4

    Abstract: Objective:: Methods:: Results:: Conclusions: ...

    Abstract Objective:
    Methods:
    Results:
    Conclusions:
    Mesh-Begriff(e) Male ; Humans ; Adolescent ; Female ; Depression/diagnosis ; Depression/drug therapy ; Outpatients ; Medication Therapy Management ; Anxiety/therapy ; Suicidal Ideation ; Treatment Outcome
    Sprache Englisch
    Erscheinungsdatum 2023-05-17
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 716287-x
    ISSN 1555-2101 ; 0160-6689
    ISSN (online) 1555-2101
    ISSN 0160-6689
    DOI 10.4088/JCP.22m14581
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