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  1. Article: Effect of Right Nostril Breathing on Cardiorespiratory Parameters and Reaction Time in Young, Healthy Humans: An Interventional Study.

    Bargal, Sheela / Nalgirkar, Vivek / Patil, Anant / Langade, Deepak

    Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine

    2024  Volume 49, Issue 2, Page(s) 303–307

    Abstract: Background and objective: Yogic breathing helps in reduction of stress and strain in the body. Right and left nostril breathings (RNB and LNB, respectively) have different effects on cardiorespiratory parameters. The study was performed to examine the ... ...

    Abstract Background and objective: Yogic breathing helps in reduction of stress and strain in the body. Right and left nostril breathings (RNB and LNB, respectively) have different effects on cardiorespiratory parameters. The study was performed to examine the effect of RNB exercise on cardiorespiratory parameters and reaction time in young, healthy human volunteers.
    Materials and methods: In this prospective, interventional study, 110 young healthy volunteers underwent systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse rate (PR), respiratory rate (RR), vital capacity (VC), peak expiratory flow rate (PEFR), and reaction time (RT) examination before and after 2 weeks of performing 45 min of RNB exercise daily.
    Results: There was notable increment in SBP (113.39 ± 17.72 vs. 117.74 ± 10.83 mmHg,
    Conclusion: RNB results in increase in blood pressure, heart rate, VC, and PEFR and decrease in ART and VRT. Further studies in patients with cardiorespiratory diseases are necessary to understand its clinical utility.
    Language English
    Publishing date 2024-03-07
    Publishing country India
    Document type Journal Article
    ZDB-ID 2085330-0
    ISSN 1998-3581 ; 0970-0218
    ISSN (online) 1998-3581
    ISSN 0970-0218
    DOI 10.4103/ijcm.ijcm_544_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Evaluation of the Effect of Left Nostril Breathing on Cardiorespiratory Parameters and Reaction Time in Young Healthy Individuals.

    Bargal, Sheela / Nalgirkar, Vivek / Patil, Anant / Langade, Deepak

    Cureus

    2022  Volume 14, Issue 2, Page(s) e22351

    Abstract: Background: Pranayama, a yogic breathing practice, produces several physiological responses in healthy individuals. Hypertension is a critical and booming public health challenge all over the world. Yoga is one of the effective methods to reduce blood ... ...

    Abstract Background: Pranayama, a yogic breathing practice, produces several physiological responses in healthy individuals. Hypertension is a critical and booming public health challenge all over the world. Yoga is one of the effective methods to reduce blood pressure (BP) and pulse rate (PR).
    Objective: To evaluate the effect of left nostril breathing (LNB) exercise on cardiorespiratory parameters and reaction time (RT) in young healthy individuals.
    Materials and methods: In this study, 106 young healthy individuals between 18 and 25 years of age were included. The systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse rate (PR), respiratory rate (RR), vital capacity (VC), peak expiratory flow rate (PEFR), and reaction time (RT) of volunteers were recorded at baseline (before exercise) and after two weeks of left nostril breathing exercise performed 45 minutes daily.
    Results:  There was a significant reduction in SBP (126.64 ± 15.51 mmHg versus 116.29 ± 11.91 mmHg; Cohen's d (effect size): 0.87; p < 0.0001)), DBP (76.57 ± 14.87 mmHg versus 71.07 ± 11.39 mmHg; Cohen's d: 0.48; p < 0.0001), PR (85.32 ± 15.44/minute versus 81.77 ± 13.02/minute; Cohen's d: 0.27; p < 0.0001), and RR (14.26 ± 2.15/minute to 13.17 ± 2.03/minute; Cohen's d: 0.54; p < 0.0001). A significant increase was observed in VC (3.42 ± 0.62 versus 3.67 ± 0.65; Cohen's d: 0.39; p < 0.0001) and PEFR (467.81 ± 46.66 versus 498.29 ± 51.50; Cohen's d: 0.59; p < 0.0001). There was a significant decrement in auditory reaction time (ART) (164.36 ± 27.20 ms versus 143.84 ± 20.32 ms; Cohen's d: 0.85; p < 0.0001) and visual reaction time (VRT) (190.25 ± 31.48 ms versus 163.75 ± 21.72 ms; Cohen's d: 0.98; p < 0.0001). There was no significant change in maximum heart rate (MHR) after cardiorespiratory activity (CRA) (p > 0.434).
    Conclusion: Left nostril breathing is associated with a decrease in cardiovascular parameters and an increase in VC and PEFR. This technique may be useful for putting up a fight against the stress and strain of daily life. This simple exercise may also be a beneficial adjuvant to pharmacological therapy in hypertensive patients.
    Language English
    Publishing date 2022-02-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.22351
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Angiogenic potential of Bambusa vulgaris leaves: Results of an in-vitro study with Chicken Embryo Chorioallantoic Membrane (CAM) model

    Gupta, Vijaykumar / Nalgirkar, Vivek / Head / Patil, Anant / Mirdha, Priyanka / Gajanan Ranade, Geetanjali

    Journal of Ayurveda and integrative medicine. 2022 July 13,

    2022  

    Abstract: The objective of study was to evaluate angiogenic potential of Bambusa vulgaris Schrad. plant extract. Chicken embryo chorioallantoic membrane model was used for estimation of angiogenic potential of Bambusa vulgaris leaves extract with different ... ...

    Abstract The objective of study was to evaluate angiogenic potential of Bambusa vulgaris Schrad. plant extract. Chicken embryo chorioallantoic membrane model was used for estimation of angiogenic potential of Bambusa vulgaris leaves extract with different concentrations. Angiogenic potential was estimated using focal application method and AbGelᵀᴹ sponge application method. The test samples were loaded on eight embryonic development day of embryonic development of chick embryo and angiogenesis was observed on eleventh embryonic development day. Counting of blood vessels and photographic evaluation was done for estimation of angiogenic potential. The sponge specimen was examined for histological changes. Angiogenic potential of Bambusa vulgaris leaves extract was compared against Plermin©. All tested concentrations (85 mcg, 170 mcg, 255 mcg, 340 mcg and 425 mcg/disc) of Bambusa vulgaris showed angiogenic potential as indicated by increase in the number of blood vessels. Maximum growth in blood vessels was seen at the concentration of 255 mcg. Photographic evaluation showed changes in angiogenesis with Bambusa vulgaris leaves extract. Angiogenic potential was also confirmed on histological examination. Plermin control groups also showed the growth of blood vessels measured by counting the number of blood vessels in photographic evaluation. The growth of blood vessels with Plermin 40 mcg was similar to Bambusa vulgaris 255 mcg. The results of current study suggest angiogenic potential of Bambusa vulgaris Schrad leaves as confirmed by visual observation and histological examination.
    Keywords Ayurvedic medicine ; Bambusa vulgaris ; angiogenesis ; blood ; chick embryos ; chorioallantoic membrane ; embryogenesis ; histology ; in vitro studies ; models
    Language English
    Dates of publication 2022-0713
    Publishing place Elsevier B.V.
    Document type Article
    Note Pre-press version
    ISSN 0975-9476
    DOI 10.1016/j.jaim.2022.100629
    Database NAL-Catalogue (AGRICOLA)

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  4. Book ; Online: Role of Respiratory Muscle Strength using MIP Testing Following COVID-19 Infection

    Agrawal, Anita / Nalgirkar, Vivek

    2020  

    Abstract: Maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) are measures of respiratory muscle strength and may be more sensitive in detecting early respiratory muscle impairment compared with spirometry. Respiratory muscle strength is a ... ...

    Abstract Maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) are measures of respiratory muscle strength and may be more sensitive in detecting early respiratory muscle impairment compared with spirometry. Respiratory muscle strength is a proven conjecturer of many diseases like muscular dystrophy, neuromuscular disease, amyotrophic lateral sclerosis and spinal muscular atrophy. Maximal inspiratory pressure is gaining interest as a test to improvise impaired respiratory muscle strength of COVID-19 patients following infection. The primary aim of this study is to discuss the potential role of respiratory muscle performance followed by coronavirus infection. The sensitivity and specificity of MIP and MEP was estimated on patients suffering with chronic lung disease. This study proposes a hypothesis that aims to screen for respiratory muscle impairment in patients with dyspnea or characteristics associated with increased risk of severe respiratory complaints.
    Keywords Maximal Inspiratory Pressure ; Maximal Expiratory Pressure ; Forced Vital Capacity ; covid19
    Language English
    Publishing date 2020-07-24
    Publisher AIJR Preprints
    Publishing country in
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  5. Article: Angiogenic potential of Bambusa vulgaris leaves: Results of an in-vitro study with chicken embryo chorioallantoic membrane (CAM) model.

    Gupta, Vijaykumar / Nalgirkar, Vivek / Patil, Anant / Mirdha, Priyanka / Ranade, Geetanjali Gajanan

    Journal of Ayurveda and integrative medicine

    2022  Volume 13, Issue 3, Page(s) 100629

    Abstract: Background: Herbal compounds have an important place in the management of wounds. However, very few compounds have been tested for their proangiogenic potential.: Objective: The objective of study was to evaluate angiogenic potential of Bambusa ... ...

    Abstract Background: Herbal compounds have an important place in the management of wounds. However, very few compounds have been tested for their proangiogenic potential.
    Objective: The objective of study was to evaluate angiogenic potential of Bambusa vulgaris Schrad. plant extract.
    Material and methods: Chicken embryo chorioallantoic membrane model was used for estimation of angiogenic potential of B. vulgaris leaves extract with different concentrations. Angiogenic potential was estimated using focal application method and AbGel™ sponge application method. The test samples were loaded on eight embryonic development day of embryonic development of chick embryo and angiogenesis was observed on eleventh embryonic development day. Counting of blood vessels and photographic evaluation was done for estimation of angiogenic potential. The sponge specimen was examined for histological changes. Angiogenic potential of B. vulgaris leaves extract was compared against Plermin©.
    Results: All tested concentrations (85 mcg, 170 mcg, 255 mcg, 340 mcg and 425 mcg/disc) of B. vulgaris showed angiogenic potential as indicated by increase in the number of blood vessels. Maximum growth in blood vessels was seen at the concentration of 255 mcg. Photographic evaluation showed changes in angiogenesis with B. vulgaris leaves extract. Angiogenic potential was also confirmed on histological examination. Plermin control groups also showed the growth of blood vessels measured by counting the number of blood vessels in photographic evaluation. The growth of blood vessels with Plermin 40 mcg was similar to B. vulgaris 255 mcg.
    Conclusion: The results of current study suggest angiogenic potential of B. vulgaris Schrad leaves as confirmed by visual observation and histological examination.
    Language English
    Publishing date 2022-09-21
    Publishing country United States
    Document type Journal Article
    ISSN 0975-9476
    ISSN 0975-9476
    DOI 10.1016/j.jaim.2022.100629
    Database MEDical Literature Analysis and Retrieval System OnLINE

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