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  1. Article ; Online: Validity of C-Reactive Protein as a Surrogate Marker for Infectious Complications After Surgery for Colorectal Cancer.

    Nam, Jin Hoon / Noh, Gyoung Tae / Chung, Soon Sup / Kim, Kwang Ho / Lee, Ryung-Ah

    Surgical infections

    2023  Volume 24, Issue 5, Page(s) 488–494

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Humans ; C-Reactive Protein/analysis ; Retrospective Studies ; Early Detection of Cancer/adverse effects ; Biomarkers ; Postoperative Complications/diagnosis ; Postoperative Complications/epidemiology ; Anastomotic Leak/diagnosis ; Anastomotic Leak/epidemiology ; ROC Curve ; Colorectal Neoplasms/surgery ; Predictive Value of Tests
    Chemical Substances C-Reactive Protein (9007-41-4) ; Biomarkers
    Language English
    Publishing date 2023-05-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1440120-4
    ISSN 1557-8674 ; 1096-2964
    ISSN (online) 1557-8674
    ISSN 1096-2964
    DOI 10.1089/sur.2022.392
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Article: Is restrictive transfusion sufficient in colorectal cancer surgery? A retrospective study before and during the COVID-19 pandemic in Korea.

    Kim, Hyeon Kyeong / Kim, Ho Seung / Noh, Gyoung Tae / Nam, Jin Hoon / Chung, Soon Sup / Kim, Kwang Ho / Lee, Ryung-Ah

    Annals of coloproctology

    2023  Volume 39, Issue 6, Page(s) 493–501

    Abstract: Purpose: Blood transfusion is one of the most common procedures used to treat anemia in colorectal surgery. Despite controversy regarding the adverse effects of blood products, surgeons have maintained standards for administering blood transfusions. ... ...

    Abstract Purpose: Blood transfusion is one of the most common procedures used to treat anemia in colorectal surgery. Despite controversy regarding the adverse effects of blood products, surgeons have maintained standards for administering blood transfusions. However, this trend was restrictive during the COVID-19 pandemic because of a shortage of blood products. In this study, we conducted an analysis to investigate whether the restriction of blood transfusions affected postoperative surgical outcomes.
    Methods: Medical records of 318 patients who underwent surgery for colon and rectal cancer at Ewha Womans University Mokdong Hospital between June 2018 and March 2022 were reviewed retrospectively. The surgical outcomes between the liberal and restrictive transfusion strategies in pre- and post-COVID-19 groups were analyzed.
    Results: In univariate analysis, postoperative transfusion was associated with infectious complications (odds ratio [OR], 1.705; 95% confidence interval [CI], 1.015-2.865; P=0.044). However, postoperative transfusion was not an independent risk factor for the development of infectious complications in multivariate analysis (OR, 1.305; 95% CI, 0.749-2.274; P=0.348). In subgroup analysis, there was no significant association between infectious complications and the hemoglobin threshold level for the administration of a transfusion (OR, 1.249; 95% CI, 0.928-1.682; P=0.142).
    Conclusion: During colorectal surgery, the decision to perform a blood transfusion is an important step in ensuring favorable surgical outcomes. According to the results of this study, restrictive transfusion is sufficient for favorable surgical outcomes compared with liberal transfusion. Therefore, modification of guidelines is suggested to minimize unnecessary transfusion-related side effects and prevent the overuse of blood products.
    Language English
    Publishing date 2023-12-28
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2711906-3
    ISSN 2287-9722 ; 2287-9714
    ISSN (online) 2287-9722
    ISSN 2287-9714
    DOI 10.3393/ac.2023.00437.0062
    Database MEDical Literature Analysis and Retrieval System OnLINE

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